Click here to switch to the map view.

The map label for this gene is hup [H]

Identifier: 86749688

GI number: 86749688

Start: 2953002

End: 2953313

Strand: Reverse

Name: hup [H]

Synonym: RPB_2570

Alternate gene names: 86749688

Gene position: 2953313-2953002 (Counterclockwise)

Preceding gene: 86749689

Following gene: 86749687

Centisome position: 55.39

GC content: 65.38

Gene sequence:

>312_bases
ATGGCGAAGAAAGCAGTTGCGAAAGCCGCGACACCCACGACCGTCACCCTGAAGCATCTCGCCGCGGCGCTCGCCGAAGA
GCACGAGTTGTCGAAGAAGCAGACCGAAGCCATCCTCGGCGACCTGGTCGGGCGCATCACCAAGCACCTGAAGAAGGGCG
AGCGGATCCGCATCGTCGGCCTCGGCATCCTGCAGGTCCGCAAGCGCGCCGCCCGCACCGGCCGCAACCCGGCCACCGGC
GAGACCATTCAGATCAAGGCCAGCAAGAAGGTCGCGTTCCGCGCCGCGAAGGAACTCAAGGAAGCCATCTGA

Upstream 100 bases:

>100_bases
CTGTTTACGGGCAAAACAGCGTATGCAGCCCCCACCCGAATCGTCTAAGGCCTGCTACGTCTTAGTTTCCTAAGCCGATA
CCAAACCCGGAGAGCTAAAA

Downstream 100 bases:

>100_bases
GCTTTCTCCTTCCACCGATCCACGCCATCCCGGAAGCCGCTCGCGGCCGCCGGGATGGCGACTGACCTGCGATCTCGTTG
TCCACGCTTTTCTGAAATCT

Product: histone-like DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 103; Mature: 102

Protein sequence:

>103_residues
MAKKAVAKAATPTTVTLKHLAAALAEEHELSKKQTEAILGDLVGRITKHLKKGERIRIVGLGILQVRKRAARTGRNPATG
ETIQIKASKKVAFRAAKELKEAI

Sequences:

>Translated_103_residues
MAKKAVAKAATPTTVTLKHLAAALAEEHELSKKQTEAILGDLVGRITKHLKKGERIRIVGLGILQVRKRAARTGRNPATG
ETIQIKASKKVAFRAAKELKEAI
>Mature_102_residues
AKKAVAKAATPTTVTLKHLAAALAEEHELSKKQTEAILGDLVGRITKHLKKGERIRIVGLGILQVRKRAARTGRNPATGE
TIQIKASKKVAFRAAKELKEAI

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=85, Percent_Identity=44.7058823529412, Blast_Score=72, Evalue=7e-15,
Organism=Escherichia coli, GI1786644, Length=80, Percent_Identity=42.5, Blast_Score=69, Evalue=9e-14,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 11115; Mature: 10984

Theoretical pI: Translated: 11.46; Mature: 11.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKAVAKAATPTTVTLKHLAAALAEEHELSKKQTEAILGDLVGRITKHLKKGERIRIVG
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
LGILQVRKRAARTGRNPATGETIQIKASKKVAFRAAKELKEAI
HHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKKAVAKAATPTTVTLKHLAAALAEEHELSKKQTEAILGDLVGRITKHLKKGERIRIVG
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
LGILQVRKRAARTGRNPATGETIQIKASKKVAFRAAKELKEAI
HHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]