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The map label for this gene is 86749470

Identifier: 86749470

GI number: 86749470

Start: 2700822

End: 2701970

Strand: Direct

Name: 86749470

Synonym: RPB_2350

Alternate gene names: NA

Gene position: 2700822-2701970 (Clockwise)

Preceding gene: 86749469

Following gene: 86749471

Centisome position: 50.66

GC content: 66.58

Gene sequence:

>1149_bases
TTGACAATAAGAGGCAAGGCTTTCATTGCCGGAATTTACGAACACCCCACGCGCCACGCGCCTGACAAATCCATCGCCCA
GCTCCACGCCGAAGTCGCCAAAGGCGCGCTCGAAGACGCCGGCCTGACCAAGGACGACATCGACGGCTATTTCTGCGCCG
GCGATGCACCGGGCGGCGGGATGGCGATGGTGGATTATCTCGGGCTGAAAGTCCGCCACCTCGACACCACCGACACCGGC
GGCTCCTCCTATCTGATCCTTCTCGCCCACGCCGCGGAGGCGATCGCGGCCGGCCGCTGCTCGGTGGCGTTGATCACGCT
GGCCGGCAAGCCGCGGACCGGCGCGCTGCCGCCGCGTCCGGTCGGCGCCGAGGGTGATTTCGAGCTGGCCTATGGCGCGA
CGACGCACAATGTCTATGCGATGTGCGCGGCGCGCCACATGCACGACTACGGCACCACGTCGGAGCAGCTCGCCTGGATC
AAGGTCGCGGCCTCGCATCACGCGCAATACAACGAGCACGCGATGCTGCGCGACGTCGTCACTGTCGAAGACGTGCTGAA
CTCGCCGCTGATCGCCGACCCGCTGCATCGGCTCGACTGCTGCGTCGTCACCGACGGCGGCGGCGCGCTGATCGTCACGT
CCGAGGCGATCGCGCGCAGCCTGAAGCGGCCGCTGGTGCGGTTGATCGGCGCCGGCGAGGCGGTCAAGGGGCCGCGCGGC
GGGCAGAAGCTCGACCTGACCTATTCGGCGGGCGTGTGGTCGGCGCCGCCGGCCTTCGAGATGGCCGGCATCACCCCGAA
GGATATCAAATACGCCTCGATCTACGACAGCTTCACCATCACCGTGCTGATGCAGCTCGAAGACCTCGGCTTCTGCAAGA
AAGGCGAGGGCGGCAAGTTCGTCGCCGACGGCAATCTGATTTCCGGCGTCGGCAAGCTGCCGTTCAACACCGATGGCGGC
GGACTGTGCAGCAATCATCCGGTGAATCGCGGCGGCATGACCAAGATTCTGGAAGCCGTGCGCCAGCTCCGCGGCGAAGC
GCATCCCAAGGTGCAGGTGCCGAACTGCGACCTCGCCATCGCCCACGGCACCGGCGGCATGCTCGGCATCCGCCACGCCG
CATCTACCTGCATTCTGGAGCGCGTGTGA

Upstream 100 bases:

>100_bases
TCCGTGACGTGGTAATTTCGCCTGCGCGCGAACACGCTTGCCAAGGTCGTTCCGAGCCGTCACAAAAAACCGTCCGACCA
AACGCCAGCGGAGAACTGCG

Downstream 100 bases:

>100_bases
TGAACAGCCCCGTGAAATATCCAGCGCCGCAAGGCAATCCGGAAACGAAGGCTTTCTGGGATGCGGCGAGCGAAGGCAAG
CTGCTGATCAAGCGTTGCCA

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MTIRGKAFIAGIYEHPTRHAPDKSIAQLHAEVAKGALEDAGLTKDDIDGYFCAGDAPGGGMAMVDYLGLKVRHLDTTDTG
GSSYLILLAHAAEAIAAGRCSVALITLAGKPRTGALPPRPVGAEGDFELAYGATTHNVYAMCAARHMHDYGTTSEQLAWI
KVAASHHAQYNEHAMLRDVVTVEDVLNSPLIADPLHRLDCCVVTDGGGALIVTSEAIARSLKRPLVRLIGAGEAVKGPRG
GQKLDLTYSAGVWSAPPAFEMAGITPKDIKYASIYDSFTITVLMQLEDLGFCKKGEGGKFVADGNLISGVGKLPFNTDGG
GLCSNHPVNRGGMTKILEAVRQLRGEAHPKVQVPNCDLAIAHGTGGMLGIRHAASTCILERV

Sequences:

>Translated_382_residues
MTIRGKAFIAGIYEHPTRHAPDKSIAQLHAEVAKGALEDAGLTKDDIDGYFCAGDAPGGGMAMVDYLGLKVRHLDTTDTG
GSSYLILLAHAAEAIAAGRCSVALITLAGKPRTGALPPRPVGAEGDFELAYGATTHNVYAMCAARHMHDYGTTSEQLAWI
KVAASHHAQYNEHAMLRDVVTVEDVLNSPLIADPLHRLDCCVVTDGGGALIVTSEAIARSLKRPLVRLIGAGEAVKGPRG
GQKLDLTYSAGVWSAPPAFEMAGITPKDIKYASIYDSFTITVLMQLEDLGFCKKGEGGKFVADGNLISGVGKLPFNTDGG
GLCSNHPVNRGGMTKILEAVRQLRGEAHPKVQVPNCDLAIAHGTGGMLGIRHAASTCILERV
>Mature_381_residues
TIRGKAFIAGIYEHPTRHAPDKSIAQLHAEVAKGALEDAGLTKDDIDGYFCAGDAPGGGMAMVDYLGLKVRHLDTTDTGG
SSYLILLAHAAEAIAAGRCSVALITLAGKPRTGALPPRPVGAEGDFELAYGATTHNVYAMCAARHMHDYGTTSEQLAWIK
VAASHHAQYNEHAMLRDVVTVEDVLNSPLIADPLHRLDCCVVTDGGGALIVTSEAIARSLKRPLVRLIGAGEAVKGPRGG
QKLDLTYSAGVWSAPPAFEMAGITPKDIKYASIYDSFTITVLMQLEDLGFCKKGEGGKFVADGNLISGVGKLPFNTDGGG
LCSNHPVNRGGMTKILEAVRQLRGEAHPKVQVPNCDLAIAHGTGGMLGIRHAASTCILERV

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=373, Percent_Identity=28.1501340482574, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI302344760, Length=333, Percent_Identity=27.9279279279279, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI302344762, Length=245, Percent_Identity=30.2040816326531, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI302344767, Length=245, Percent_Identity=30.2040816326531, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI55956775, Length=212, Percent_Identity=28.3018867924528, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17537653, Length=365, Percent_Identity=24.6575342465753, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24585051, Length=387, Percent_Identity=28.6821705426357, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI19921506, Length=386, Percent_Identity=27.979274611399, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 40184; Mature: 40052

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRGKAFIAGIYEHPTRHAPDKSIAQLHAEVAKGALEDAGLTKDDIDGYFCAGDAPGGG
CCCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCC
MAMVDYLGLKVRHLDTTDTGGSSYLILLAHAAEAIAAGRCSVALITLAGKPRTGALPPRP
CHHHHHHCEEEEEECCCCCCCCEEEEEEEEHHHHHHCCCCEEEEEEEECCCCCCCCCCCC
VGAEGDFELAYGATTHNVYAMCAARHMHDYGTTSEQLAWIKVAASHHAQYNEHAMLRDVV
CCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHEEEEEEEHHHCCCCCCHHHHHHHH
TVEDVLNSPLIADPLHRLDCCVVTDGGGALIVTSEAIARSLKRPLVRLIGAGEAVKGPRG
HHHHHHCCCCHHCCHHHCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCC
GQKLDLTYSAGVWSAPPAFEMAGITPKDIKYASIYDSFTITVLMQLEDLGFCKKGEGGKF
CCEEEEEEECCCCCCCCCCEECCCCHHHCEEEEECCCEEEEEEEEEHHCCCCCCCCCCEE
VADGNLISGVGKLPFNTDGGGLCSNHPVNRGGMTKILEAVRQLRGEAHPKVQVPNCDLAI
EECCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEE
AHGTGGMLGIRHAASTCILERV
EECCCCCEEHHHHHHHHHHCCC
>Mature Secondary Structure 
TIRGKAFIAGIYEHPTRHAPDKSIAQLHAEVAKGALEDAGLTKDDIDGYFCAGDAPGGG
CCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCC
MAMVDYLGLKVRHLDTTDTGGSSYLILLAHAAEAIAAGRCSVALITLAGKPRTGALPPRP
CHHHHHHCEEEEEECCCCCCCCEEEEEEEEHHHHHHCCCCEEEEEEEECCCCCCCCCCCC
VGAEGDFELAYGATTHNVYAMCAARHMHDYGTTSEQLAWIKVAASHHAQYNEHAMLRDVV
CCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHEEEEEEEHHHCCCCCCHHHHHHHH
TVEDVLNSPLIADPLHRLDCCVVTDGGGALIVTSEAIARSLKRPLVRLIGAGEAVKGPRG
HHHHHHCCCCHHCCHHHCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCC
GQKLDLTYSAGVWSAPPAFEMAGITPKDIKYASIYDSFTITVLMQLEDLGFCKKGEGGKF
CCEEEEEEECCCCCCCCCCEECCCCHHHCEEEEECCCEEEEEEEEEHHCCCCCCCCCCEE
VADGNLISGVGKLPFNTDGGGLCSNHPVNRGGMTKILEAVRQLRGEAHPKVQVPNCDLAI
EECCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEE
AHGTGGMLGIRHAASTCILERV
EECCCCCEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]