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The map label for this gene is rpfG [H]

Identifier: 86749450

GI number: 86749450

Start: 2678109

End: 2679509

Strand: Direct

Name: rpfG [H]

Synonym: RPB_2330

Alternate gene names: 86749450

Gene position: 2678109-2679509 (Clockwise)

Preceding gene: 86749449

Following gene: 86749451

Centisome position: 50.23

GC content: 64.45

Gene sequence:

>1401_bases
ATGTCGGCTTGGGGTCATTCAGCGGAATGGGGAGCGGGACGGAGCGGCGAGGCGGTTCGCGGCCGTCCGCACGACGGGTT
GCGGTTGCGGCCGCTGCTGGTGTTCGACGACCCCGCCTATGAGAGCGACTTCGTTCGCTACTACAACAGATTCTACTATC
GCTACGCGCAAGTCAGCCTGATCGTCGGGATGCTGCTGGTGTCGGCCGATTTCCTCGTCGACCTGCTCGCATCCAAGGCC
ACGCCGGCGAATCTCGATCGCCTACTGCTCTGCGTGCCGCTGCTCGGCCTCGGCCTCGTCGGCTCGTTCGCCGACTACGC
GCGGCGCCACTGGCAGCCGGTGATGTCCGGACTGATCACGGCGATCGCCGGCAGCCTGTTCTGGGTGCTGCTGGTGATCG
ACAACCAGGGCGGCATGGGCATGACGTCGTGGGTCGGCATCCTCAACTTCGTATTTCTCGAATTCTATTGCTTCGTCGTT
CTCGGCGTCCAGTTCAGGTATGCGCTCGCAGCGGGTGCGATCGTTCTGGCGATGTTCGAACTCGCATTGCTGCGCGCGAT
CGGCGCGGACAGCGGCGCGTTTCTGTACTTGTCGTATCATGCGGCGACTCTGTTCATCCTGGCCGCGGGCATCGGCTGGT
GGCGGGAATTCCTGCTGCGCAAGGGGTTTGCGGCGCAGACCAGCCTGAGGGCGGCGCAGAACGTCCTGAGGAACCAGAAC
GGCCATCTCGAGCTCGAGGTGGAGAAAAGCACCCAGCGGATTCAGCGCACCCAGGACGTCACCATCGAGATCCTGACCTC
GCTGGCGGAGACCCGCGACAACGAAACCGGCAACCACATTCGCCGGACCCAGCATTATGTCAGGGCCCTGGCCCGCCGCC
TGCAGTCGCACCCGGCCTTCGCGGCCTATCTGGTGGAGGCGCAGATCGACATGCTGTTCAAATACGCGCCGCTGCACGAC
ATCGGCAAGGTCGGCATTCCCGACAGCATTCTGCTCAAGCCGGGCAAGCTCGATCCGCACGAATTCGAAATCATGAAGAC
CCACACCACGCTCGGTTACCAGACCATCGTGAACGCCGAAAAGCGGCTCGGCACGCCGGTGGCGTTTCTCGCCTGCGCCA
AGGAGATCGCGCTCAGCCATCACGAGCACTGGGACGGCAACGGCTACCCGAACCGGCTGGCGGGCGAGGCGATTCCGATC
TCGGCCCGGCTGATGGCGGTGGCCGATGTCTACGACGCGCTGACCTCGCGCCGGGTCTACAAGGACGCGATGCCGCACGA
TCGGGCGGTCGCGATCATCAAGGACGGCAGCGGCCGGCAATTCGACCCCGACGTGGTCGACGCGTTCGTCGCCATTGCCG
CCGATGAATTCAAGACGATCGCGGCCCGCTACGCGGACTGA

Upstream 100 bases:

>100_bases
TGGTGGCGCTAGCGGCTATCGATAGCGATTTGCCGCTAGTCGATGCGATCGCGCCCGGGCCCTCCGGAACGTCTCGCCAT
CGTCGGATGGGGCGTCCTCG

Downstream 100 bases:

>100_bases
GCCGGCCGGGCGGCCATATGCACCGTCACAGCGCGGCAGCCTGCCTCTGCCTGCTACGCCAATTGTTAAATAATCAAAGG
TAGCATTCGCCATCCTCGTG

Product: metal dependent phosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSAWGHSAEWGAGRSGEAVRGRPHDGLRLRPLLVFDDPAYESDFVRYYNRFYYRYAQVSLIVGMLLVSADFLVDLLASKA
TPANLDRLLLCVPLLGLGLVGSFADYARRHWQPVMSGLITAIAGSLFWVLLVIDNQGGMGMTSWVGILNFVFLEFYCFVV
LGVQFRYALAAGAIVLAMFELALLRAIGADSGAFLYLSYHAATLFILAAGIGWWREFLLRKGFAAQTSLRAAQNVLRNQN
GHLELEVEKSTQRIQRTQDVTIEILTSLAETRDNETGNHIRRTQHYVRALARRLQSHPAFAAYLVEAQIDMLFKYAPLHD
IGKVGIPDSILLKPGKLDPHEFEIMKTHTTLGYQTIVNAEKRLGTPVAFLACAKEIALSHHEHWDGNGYPNRLAGEAIPI
SARLMAVADVYDALTSRRVYKDAMPHDRAVAIIKDGSGRQFDPDVVDAFVAIAADEFKTIAARYAD

Sequences:

>Translated_466_residues
MSAWGHSAEWGAGRSGEAVRGRPHDGLRLRPLLVFDDPAYESDFVRYYNRFYYRYAQVSLIVGMLLVSADFLVDLLASKA
TPANLDRLLLCVPLLGLGLVGSFADYARRHWQPVMSGLITAIAGSLFWVLLVIDNQGGMGMTSWVGILNFVFLEFYCFVV
LGVQFRYALAAGAIVLAMFELALLRAIGADSGAFLYLSYHAATLFILAAGIGWWREFLLRKGFAAQTSLRAAQNVLRNQN
GHLELEVEKSTQRIQRTQDVTIEILTSLAETRDNETGNHIRRTQHYVRALARRLQSHPAFAAYLVEAQIDMLFKYAPLHD
IGKVGIPDSILLKPGKLDPHEFEIMKTHTTLGYQTIVNAEKRLGTPVAFLACAKEIALSHHEHWDGNGYPNRLAGEAIPI
SARLMAVADVYDALTSRRVYKDAMPHDRAVAIIKDGSGRQFDPDVVDAFVAIAADEFKTIAARYAD
>Mature_465_residues
SAWGHSAEWGAGRSGEAVRGRPHDGLRLRPLLVFDDPAYESDFVRYYNRFYYRYAQVSLIVGMLLVSADFLVDLLASKAT
PANLDRLLLCVPLLGLGLVGSFADYARRHWQPVMSGLITAIAGSLFWVLLVIDNQGGMGMTSWVGILNFVFLEFYCFVVL
GVQFRYALAAGAIVLAMFELALLRAIGADSGAFLYLSYHAATLFILAAGIGWWREFLLRKGFAAQTSLRAAQNVLRNQNG
HLELEVEKSTQRIQRTQDVTIEILTSLAETRDNETGNHIRRTQHYVRALARRLQSHPAFAAYLVEAQIDMLFKYAPLHDI
GKVGIPDSILLKPGKLDPHEFEIMKTHTTLGYQTIVNAEKRLGTPVAFLACAKEIALSHHEHWDGNGYPNRLAGEAIPIS
ARLMAVADVYDALTSRRVYKDAMPHDRAVAIIKDGSGRQFDPDVVDAFVAIAADEFKTIAARYAD

Specific function: Positively regulates the synthesis of extracellular enzymes and extracellular polysaccharides. The cell-cell signaling system encoded by rpf genes is required for full virulence and is implicated in regulation of the formation and dispersal of biofilms [H

COG id: COG3437

COG function: function code KT; Response regulator containing a CheY-like receiver domain and an HD-GYP domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR003607
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 51789; Mature: 51658

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAWGHSAEWGAGRSGEAVRGRPHDGLRLRPLLVFDDPAYESDFVRYYNRFYYRYAQVSL
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
IVGMLLVSADFLVDLLASKATPANLDRLLLCVPLLGLGLVGSFADYARRHWQPVMSGLIT
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIAGSLFWVLLVIDNQGGMGMTSWVGILNFVFLEFYCFVVLGVQFRYALAAGAIVLAMFE
HHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALLRAIGADSGAFLYLSYHAATLFILAAGIGWWREFLLRKGFAAQTSLRAAQNVLRNQN
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
GHLELEVEKSTQRIQRTQDVTIEILTSLAETRDNETGNHIRRTQHYVRALARRLQSHPAF
CCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
AAYLVEAQIDMLFKYAPLHDIGKVGIPDSILLKPGKLDPHEFEIMKTHTTLGYQTIVNAE
HHHHHHHHHHHHHHHCCCHHCCCCCCCCCEEECCCCCCCCCEEEEEHHHHHHHHHHHCCH
KRLGTPVAFLACAKEIALSHHEHWDGNGYPNRLAGEAIPISARLMAVADVYDALTSRRVY
HHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KDAMPHDRAVAIIKDGSGRQFDPDVVDAFVAIAADEFKTIAARYAD
HHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAWGHSAEWGAGRSGEAVRGRPHDGLRLRPLLVFDDPAYESDFVRYYNRFYYRYAQVSL
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
IVGMLLVSADFLVDLLASKATPANLDRLLLCVPLLGLGLVGSFADYARRHWQPVMSGLIT
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIAGSLFWVLLVIDNQGGMGMTSWVGILNFVFLEFYCFVVLGVQFRYALAAGAIVLAMFE
HHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALLRAIGADSGAFLYLSYHAATLFILAAGIGWWREFLLRKGFAAQTSLRAAQNVLRNQN
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
GHLELEVEKSTQRIQRTQDVTIEILTSLAETRDNETGNHIRRTQHYVRALARRLQSHPAF
CCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
AAYLVEAQIDMLFKYAPLHDIGKVGIPDSILLKPGKLDPHEFEIMKTHTTLGYQTIVNAE
HHHHHHHHHHHHHHHCCCHHCCCCCCCCCEEECCCCCCCCCEEEEEHHHHHHHHHHHCCH
KRLGTPVAFLACAKEIALSHHEHWDGNGYPNRLAGEAIPISARLMAVADVYDALTSRRVY
HHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KDAMPHDRAVAIIKDGSGRQFDPDVVDAFVAIAADEFKTIAARYAD
HHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11123673 [H]