Click here to switch to the map view.

The map label for this gene is rpoC [H]

Identifier: 86749406

GI number: 86749406

Start: 2638678

End: 2642880

Strand: Direct

Name: rpoC [H]

Synonym: RPB_2286

Alternate gene names: 86749406

Gene position: 2638678-2642880 (Clockwise)

Preceding gene: 86749405

Following gene: 86749407

Centisome position: 49.49

GC content: 63.88

Gene sequence:

>4203_bases
ATGAACCAAGAAATCATGAATCTGTTCAATCCGACGACGCCGGCTCAGGTCTTCGACCAGATCCGGATCTCGATCGCGTC
GCCGGAGAAGATTCTGTCGTGGTCCTACGGCGAGATCAAGAAGCCGGAAACCATCAATTACCGCACCTTCAAGCCCGAGC
GCGACGGCCTGTTCTGCGCCCGCATCTTCGGGCCGATCAAGGATTACGAGTGCTTGTGCGGCAAGTACAAGCGGATGAAG
TACAAGGGCATCATCTGCGAGAAGTGCTCGGTCGAAGTGACGCTGTCGCGCGTCCGACGCGAGCGCATGGGCCACATCGA
GCTGGCGGCACCGGTCGCCCACATCTGGTTCCTGAAGTCCTTGCCGTCGCGGATCGGGCAGTTGCTCGACATGACGCTGA
AGGACCTCGAGCGGATTCTGTACTTCGAATACTACGTCGTGCTGGAGCCGGGCCTGACCGACCTCAAGGAGCGTCAGCTG
CTGTCGGAGGAGGAGTACCTCCGCGCCCAGGATCAGTACGGCCAGGACAGCTTCACCGCCATGATCGGCGCCGAAGCGAT
CCGCGAATTGCTGAAGGGACTCGAGCTCGAGAAGATCGATGCGCAGCTGCGCGTCGAGATGGCCGAGACCGACTCCGACA
TCAAGCACAAGAAGCTCGCCAAGCGGCTGAAGATCGTCGAGGCGTTCCGCTTCTCCGGCAACAAGCCGGAGTGGATGATC
CTGACCGTGGTGCCGGTGATTCCGCCGGACCTGCGGCCGCTGGTGCCGCTCGACGGCGGCCGGTTCGCGACCTCGGATCT
GAACGACCTGTATCGCCGCGTCATCAACCGTAACAACCGGTTGAAGCGGCTGATGGAGCTGCGCGCGCCGGACATCATCA
TCCGCAACGAAAAGCGGATGCTGCAGGAAGCCGTCGACGCGTTGTTCGACAACGGCCGCCGCGGCCGCGTCATCACCGGC
GCCAACAAGCGTCCGTTGAAGTCGCTCGCCGACATGCTGAAGGGCAAGCAGGGTCGGTTCCGTCAGAACCTGCTCGGCAA
GCGCGTCGACTATTCGGGCCGTTCGGTCATCGTCGTCGGCCCCGAGCTGAAGCTGCACCAGTGCGGCCTGCCGAAGAAGA
TGGCGCTCGAACTGTTCAAGCCGTTCATCTATTCGCGGCTCGACGCCAAGGGTCTGTCGACCACGGTGAAGCAGGCGAAG
AAGCTCGTCGAAAAGGAGCGTCCCGAGGTCTGGGACATCCTCGACGAAGTCATTCGCGAGCATCCGGTGCTGCTGAACCG
CGCCCCGACGCTGCATCGCCTCGGCATCCAGGCGTTCGAGCCGGTGCTGATCGAGGGCAAGGCGATCCAGCTTCACCCGC
TGGTCTGCGCCGCGTTCAACGCCGATTTCGACGGCGACCAGATGGCCGTGCACGTCCCGCTGTCGCTCGAAGCGCAGCTC
GAAGCGCGCGTGCTGATGATGTCGACCAACAACATCCTGCATCCGGCGAACGGCCAGCCGATCATCGTGCCGTCGCAGGA
CATCGTGCTCGGCCTGTACTACCTGTCGATCCTGCGGGAAGGGCTGCCGGGCGAGGGCAAGGTGTTCGGCGACCTCGCCG
AGCTGGAGCACGCGCTGTTCTCCAAGGTCATCCACCTGCACACCAAGATCAAATATCGCTGGGACTCGCTCGACGACGAG
GGCAAGCCGTACCAGCGGCTGATCGAGACCACCGCCGGCCGCATCCTGCTCGGCCAGGTTCTGCCGAAATCGGTGAAGCT
GCCGTTCGAGGTCATCAACAAGCTGATGACCAAGCGCGAGATCTCCAGCGTGATCGATCAGGTCTATCGCCACTGCGGCC
AGAAGGAGACGGTGATCTTCTGCGACCGCATCATGGCGCTGGGCTTCTTCAACGCGTTCAAGGCGGGCATCTCGTTCGGC
AAGGACGACATGGTCGTGCCGGCCTCGAAGTGGAAGATCGTCGACACCACGCGTACGCTGGCGAAGGATTTCGAGCAGCA
GTACAACGACGGTCTGATCACCCACGGCGAGAAGTACAACAAGGTGGTCGACGCCTGGTCGAAGGCCACCGAGGAAATCG
CCAAGGAGATGATGAAGGAGATCTCCGCGGTCCGGAAGAACGCATCCGGCGCGGAGACCCAGGTCAACTCGATCTACATG
ATGGCCCATTCCGGCGCGCGTGGTTCGCCCGCCCAGATGCGTCAGCTCGCCGGCATGCGCGGCCTGATGGCCAAGCCGTC
GGGTGAGATCATCGAGACGCCGATCATCTCGAACTTCAAGGAAGGCCTCTCGGTTCTCGAGTACTTCAACTCGACCCACG
GCGCCCGTAAGGGCCTCGCGGACACCGCGTTGAAGACCGCGAACTCCGGCTACCTGACCCGCCGTCTGGTCGACGTGGCG
CAGGACTGCATCATCACCCAGGATGATTGCGGCACCTCGCTCGGCATCAAGATGCGGGCGATCATCGACGCCGGCACCGT
GGTGGCGTCGCTCGGCTCGCGCATCCTCGGCCGCACCGCGGGCGAAGACGTGCGCGATCCGCAGACCAACGAGGTGATCG
TCAAGAAGGGCCAGCTGATGGAGGAGCGCGACGTCGAGGCGATCCACCAGGCCGGCGTCCAGGAAGTGAAGATCCGCTCG
GCGCTGACCTGCGAACTGGTCAACGGCATCTGCGGCAAGTGCTACGGGCGCGATCTCGCCCGCGGCACCCCGGTCAACCA
CGGCGAGGCGGTCGGTGTCATCGCCGCGCAGTCGATCGGCGAACCCGGCACGCAGCTGACGATGCGTACCTTCCACATCG
GCGGCGCGGCGCAGATCAACGAGCAGTCGGTGATCGAGTCGAACTTCGAGGGTAAGGTCGTCATCAAGAACAAGGCGATC
GCCCGCAACGGCGAGAACCACAGCGTCGCGATGGTTCGCAACATGGTGGTTGCGATCGTCGATCCGGACGGCACCGAACG
GGCGACCCACCGCATCCAGTACGGCGCGCGCATGCACGTCGACGAGGGCGACACGGTGAAGCGCGGCCAGCGCATCGCCG
AGTGGGATCCGTACAGCCGCCCGGTGCTGACCGAGGTCGAGGGCACGATCGATTTCGAGGATCTGGTCGAAGACCAGTCG
ATCTCGGAAACGCTCGACGAATCCACCGGCATCGCCAAGCGTATCGTCATCGACTGGCGCTCGACCCGCGGCGGCGCCGA
TCTGCGCCCGGCGATCGTGGTCAAGGGCAAGGACGGCAAGGTGCTGAAGCTGGCGCGCGGCGGTGACGCCCGCTACATGC
TGTCGGTCGACGCCATTCTGTCGGTCGACGTCGGCGCCAAGGTGAAGCCGGGCGACATCCTCGCGCGTATCTCGACCGAG
AGCGCGAAGACCCGCGACATCACCGGCGGTCTGCCGCGCGTCGCCGAACTGTTCGAGGCCCGCAAGCCGAAGGACGCGGC
GATCATCGCGGAAATCGCCGGCACCATCCGGTTCGGCCGCGACTACAAGAACAAGCGTCGGATCTCGATCGAACCGATGG
ACAGCGAAGAAGAGGCGCGCGAGTACCTGATCCCGAAGGGCAAGCACATCCACCTTCAGGACGGCGACATCGTGGAAAAG
GGCGACTTCATCGTCGAAGGCAACCCGGCGCCGCACGACATCCTGGCGATCAAGGGCATCGAGGAACTCGCTGCCTATCT
GGTCAACGAAATCCAGGAGGTCTACCGGCTCCAGGGCGTGTTGATCAACGACAAGCACATCGAGGTGATCGTTCGCCAGA
TGCTGCAGAAGGTCGAGATCACCGACCAGGGCGAGACCGACATGATCTCGGGCGAACAGATCGACAAGATCGAGTTCGAC
CAGCTCAACGCCAAGGCGCGCGACGAGGGCAAGAAGATCGCCACGGGAACGCCGGTTCTGCTCGGCATCACCAAGGCGAG
CCTGCAGACCCGCTCGTTCTTCTCGGCGGCGTCGTTCCAGGAGACCACCCGCGTGCTCACCGAAGCCGCCGTCAACGGCA
AGGTGGACCCGCTGGAAGGCCTCAAGGAAAACGTCATCGTCGGCCGGCTGATCCCGGCCGGCACCGGCGCCTCGATGGCC
AAGCTCCGCGAAGTCGCGATGAAGCGGGATCGCATGATCCTCGACGAACGCGAGAAGCAGGCGACCATCGTGCCGCCCGC
GGCCCCGGAAGCCGAGCCGCTGGCGCTGCCGCCGGTCGAATAA

Upstream 100 bases:

>100_bases
GCCGGGCGTCCTGCCGCGCAGACGCGATGCGCGCGGTCGGGAGCGACCTAAAGAAATTCGAATTTGCTGCCGGTGACGAT
CGGTACGCGAGGAGAAGACG

Downstream 100 bases:

>100_bases
GGCGGCTTCTGCAAAGCAATCTGAAAAAGGCCGGCGCAAGCCGGCCTTTTTTGCGTCTGGCCGACTTTTCGGGCTACGCA
TTACGGTCCGTTCATGTTTC

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1400; Mature: 1400

Protein sequence:

>1400_residues
MNQEIMNLFNPTTPAQVFDQIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGIICEKCSVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGQLLDMTLKDLERILYFEYYVVLEPGLTDLKERQL
LSEEEYLRAQDQYGQDSFTAMIGAEAIRELLKGLELEKIDAQLRVEMAETDSDIKHKKLAKRLKIVEAFRFSGNKPEWMI
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITG
ANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYSRLDAKGLSTTVKQAK
KLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSILREGLPGEGKVFGDLAELEHALFSKVIHLHTKIKYRWDSLDDE
GKPYQRLIETTAGRILLGQVLPKSVKLPFEVINKLMTKREISSVIDQVYRHCGQKETVIFCDRIMALGFFNAFKAGISFG
KDDMVVPASKWKIVDTTRTLAKDFEQQYNDGLITHGEKYNKVVDAWSKATEEIAKEMMKEISAVRKNASGAETQVNSIYM
MAHSGARGSPAQMRQLAGMRGLMAKPSGEIIETPIISNFKEGLSVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVA
QDCIITQDDCGTSLGIKMRAIIDAGTVVASLGSRILGRTAGEDVRDPQTNEVIVKKGQLMEERDVEAIHQAGVQEVKIRS
ALTCELVNGICGKCYGRDLARGTPVNHGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQINEQSVIESNFEGKVVIKNKAI
ARNGENHSVAMVRNMVVAIVDPDGTERATHRIQYGARMHVDEGDTVKRGQRIAEWDPYSRPVLTEVEGTIDFEDLVEDQS
ISETLDESTGIAKRIVIDWRSTRGGADLRPAIVVKGKDGKVLKLARGGDARYMLSVDAILSVDVGAKVKPGDILARISTE
SAKTRDITGGLPRVAELFEARKPKDAAIIAEIAGTIRFGRDYKNKRRISIEPMDSEEEAREYLIPKGKHIHLQDGDIVEK
GDFIVEGNPAPHDILAIKGIEELAAYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITDQGETDMISGEQIDKIEFD
QLNAKARDEGKKIATGTPVLLGITKASLQTRSFFSAASFQETTRVLTEAAVNGKVDPLEGLKENVIVGRLIPAGTGASMA
KLREVAMKRDRMILDEREKQATIVPPAAPEAEPLALPPVE

Sequences:

>Translated_1400_residues
MNQEIMNLFNPTTPAQVFDQIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGIICEKCSVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGQLLDMTLKDLERILYFEYYVVLEPGLTDLKERQL
LSEEEYLRAQDQYGQDSFTAMIGAEAIRELLKGLELEKIDAQLRVEMAETDSDIKHKKLAKRLKIVEAFRFSGNKPEWMI
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITG
ANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYSRLDAKGLSTTVKQAK
KLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSILREGLPGEGKVFGDLAELEHALFSKVIHLHTKIKYRWDSLDDE
GKPYQRLIETTAGRILLGQVLPKSVKLPFEVINKLMTKREISSVIDQVYRHCGQKETVIFCDRIMALGFFNAFKAGISFG
KDDMVVPASKWKIVDTTRTLAKDFEQQYNDGLITHGEKYNKVVDAWSKATEEIAKEMMKEISAVRKNASGAETQVNSIYM
MAHSGARGSPAQMRQLAGMRGLMAKPSGEIIETPIISNFKEGLSVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVA
QDCIITQDDCGTSLGIKMRAIIDAGTVVASLGSRILGRTAGEDVRDPQTNEVIVKKGQLMEERDVEAIHQAGVQEVKIRS
ALTCELVNGICGKCYGRDLARGTPVNHGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQINEQSVIESNFEGKVVIKNKAI
ARNGENHSVAMVRNMVVAIVDPDGTERATHRIQYGARMHVDEGDTVKRGQRIAEWDPYSRPVLTEVEGTIDFEDLVEDQS
ISETLDESTGIAKRIVIDWRSTRGGADLRPAIVVKGKDGKVLKLARGGDARYMLSVDAILSVDVGAKVKPGDILARISTE
SAKTRDITGGLPRVAELFEARKPKDAAIIAEIAGTIRFGRDYKNKRRISIEPMDSEEEAREYLIPKGKHIHLQDGDIVEK
GDFIVEGNPAPHDILAIKGIEELAAYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITDQGETDMISGEQIDKIEFD
QLNAKARDEGKKIATGTPVLLGITKASLQTRSFFSAASFQETTRVLTEAAVNGKVDPLEGLKENVIVGRLIPAGTGASMA
KLREVAMKRDRMILDEREKQATIVPPAAPEAEPLALPPVE
>Mature_1400_residues
MNQEIMNLFNPTTPAQVFDQIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGIICEKCSVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGQLLDMTLKDLERILYFEYYVVLEPGLTDLKERQL
LSEEEYLRAQDQYGQDSFTAMIGAEAIRELLKGLELEKIDAQLRVEMAETDSDIKHKKLAKRLKIVEAFRFSGNKPEWMI
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITG
ANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYSRLDAKGLSTTVKQAK
KLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSILREGLPGEGKVFGDLAELEHALFSKVIHLHTKIKYRWDSLDDE
GKPYQRLIETTAGRILLGQVLPKSVKLPFEVINKLMTKREISSVIDQVYRHCGQKETVIFCDRIMALGFFNAFKAGISFG
KDDMVVPASKWKIVDTTRTLAKDFEQQYNDGLITHGEKYNKVVDAWSKATEEIAKEMMKEISAVRKNASGAETQVNSIYM
MAHSGARGSPAQMRQLAGMRGLMAKPSGEIIETPIISNFKEGLSVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVA
QDCIITQDDCGTSLGIKMRAIIDAGTVVASLGSRILGRTAGEDVRDPQTNEVIVKKGQLMEERDVEAIHQAGVQEVKIRS
ALTCELVNGICGKCYGRDLARGTPVNHGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQINEQSVIESNFEGKVVIKNKAI
ARNGENHSVAMVRNMVVAIVDPDGTERATHRIQYGARMHVDEGDTVKRGQRIAEWDPYSRPVLTEVEGTIDFEDLVEDQS
ISETLDESTGIAKRIVIDWRSTRGGADLRPAIVVKGKDGKVLKLARGGDARYMLSVDAILSVDVGAKVKPGDILARISTE
SAKTRDITGGLPRVAELFEARKPKDAAIIAEIAGTIRFGRDYKNKRRISIEPMDSEEEAREYLIPKGKHIHLQDGDIVEK
GDFIVEGNPAPHDILAIKGIEELAAYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITDQGETDMISGEQIDKIEFD
QLNAKARDEGKKIATGTPVLLGITKASLQTRSFFSAASFQETTRVLTEAAVNGKVDPLEGLKENVIVGRLIPAGTGASMA
KLREVAMKRDRMILDEREKQATIVPPAAPEAEPLALPPVE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI39725938, Length=856, Percent_Identity=26.0514018691589, Blast_Score=184, Evalue=8e-46,
Organism=Homo sapiens, GI4505939, Length=934, Percent_Identity=23.8758029978587, Blast_Score=182, Evalue=2e-45,
Organism=Homo sapiens, GI103471997, Length=245, Percent_Identity=30.6122448979592, Blast_Score=95, Evalue=4e-19,
Organism=Escherichia coli, GI2367335, Length=1399, Percent_Identity=58.6132952108649, Blast_Score=1637, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=736, Percent_Identity=26.2228260869565, Blast_Score=174, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71987878, Length=664, Percent_Identity=26.5060240963855, Blast_Score=162, Evalue=8e-40,
Organism=Saccharomyces cerevisiae, GI6320061, Length=931, Percent_Identity=24.7046186895811, Blast_Score=176, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6324690, Length=586, Percent_Identity=26.7918088737201, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI17530899, Length=845, Percent_Identity=23.3136094674556, Blast_Score=166, Evalue=1e-40,
Organism=Drosophila melanogaster, GI281360912, Length=308, Percent_Identity=31.1688311688312, Blast_Score=133, Evalue=8e-31,
Organism=Drosophila melanogaster, GI17647875, Length=335, Percent_Identity=26.2686567164179, Blast_Score=100, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 156042; Mature: 156042

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQEIMNLFNPTTPAQVFDQIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCA
CCHHHHHHCCCCCHHHHHHHHHEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPIKDYECLCGKYKRMKYKGIICEKCSVEVTLSRVRRERMGHIELAAPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHEECCEEECCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
LPSRIGQLLDMTLKDLERILYFEYYVVLEPGLTDLKERQLLSEEEYLRAQDQYGQDSFTA
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCHHHHHHHHHHCCCHHHHH
MIGAEAIRELLKGLELEKIDAQLRVEMAETDSDIKHKKLAKRLKIVEAFRFSGNKPEWMI
HHHHHHHHHHHHCCCCHHCCHHHEEEEHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRM
EEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQEAVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PELKLHQCGLPKKMALELFKPFIYSRLDAKGLSTTVKQAKKLVEKERPEVWDILDEVIRE
CCCEEHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCEECCCC
EARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSILREGLPGEGKVFGDLAELEHALF
CEEEEEEECCCEEECCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
SKVIHLHTKIKYRWDSLDDEGKPYQRLIETTAGRILLGQVLPKSVKLPFEVINKLMTKRE
HHHHHHHHHEEEEECCCCCCCCHHHHHHHHHCCCEEEHHHCCCCCCCCHHHHHHHHHHHH
ISSVIDQVYRHCGQKETVIFCDRIMALGFFNAFKAGISFGKDDMVVPASKWKIVDTTRTL
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEHHHHHH
AKDFEQQYNDGLITHGEKYNKVVDAWSKATEEIAKEMMKEISAVRKNASGAETQVNSIYM
HHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCEEEE
MAHSGARGSPAQMRQLAGMRGLMAKPSGEIIETPIISNFKEGLSVLEYFNSTHGARKGLA
EEECCCCCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHCCHHHCCHH
DTALKTANSGYLTRRLVDVAQDCIITQDDCGTSLGIKMRAIIDAGTVVASLGSRILGRTA
HHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCC
GEDVRDPQTNEVIVKKGQLMEERDVEAIHQAGVQEVKIRSALTCELVNGICGKCYGRDLA
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RGTPVNHGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQINEQSVIESNFEGKVVIKNKAI
CCCCCCCCCEEEEEEHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHCCCCCEEEEECCHH
ARNGENHSVAMVRNMVVAIVDPDGTERATHRIQYGARMHVDEGDTVKRGQRIAEWDPYSR
HCCCCCCHHHEEECEEEEEECCCCCHHHHHHHHCCCEEECCCCCHHHHCCCCCCCCCCCC
PVLTEVEGTIDFEDLVEDQSISETLDESTGIAKRIVIDWRSTRGGADLRPAIVVKGKDGK
CEEECCCCCCCHHHHHCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCEEEEECCCCC
VLKLARGGDARYMLSVDAILSVDVGAKVKPGDILARISTESAKTRDITGGLPRVAELFEA
EEEEEECCCCEEEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHC
RKPKDAAIIAEIAGTIRFGRDYKNKRRISIEPMDSEEEAREYLIPKGKHIHLQDGDIVEK
CCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHCCCCCCEEEECCCCEEEC
GDFIVEGNPAPHDILAIKGIEELAAYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEI
CCEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHCCC
TDQGETDMISGEQIDKIEFDQLNAKARDEGKKIATGTPVLLGITKASLQTRSFFSAASFQ
CCCCCCCCCCCCCCCCCCHHHCCCCHHHCCCEEECCCCEEEEEEHHHHHHHHHHHHHHHH
ETTRVLTEAAVNGKVDPLEGLKENVIVGRLIPAGTGASMAKLREVAMKRDRMILDEREKQ
HHHHHHHHHHHCCCCCHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
ATIVPPAAPEAEPLALPPVE
CEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNQEIMNLFNPTTPAQVFDQIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCA
CCHHHHHHCCCCCHHHHHHHHHEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPIKDYECLCGKYKRMKYKGIICEKCSVEVTLSRVRRERMGHIELAAPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHEECCEEECCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
LPSRIGQLLDMTLKDLERILYFEYYVVLEPGLTDLKERQLLSEEEYLRAQDQYGQDSFTA
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCHHHHHHHHHHCCCHHHHH
MIGAEAIRELLKGLELEKIDAQLRVEMAETDSDIKHKKLAKRLKIVEAFRFSGNKPEWMI
HHHHHHHHHHHHCCCCHHCCHHHEEEEHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LTVVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIIRNEKRM
EEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQEAVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PELKLHQCGLPKKMALELFKPFIYSRLDAKGLSTTVKQAKKLVEKERPEVWDILDEVIRE
CCCEEHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCEECCCC
EARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSILREGLPGEGKVFGDLAELEHALF
CEEEEEEECCCEEECCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
SKVIHLHTKIKYRWDSLDDEGKPYQRLIETTAGRILLGQVLPKSVKLPFEVINKLMTKRE
HHHHHHHHHEEEEECCCCCCCCHHHHHHHHHCCCEEEHHHCCCCCCCCHHHHHHHHHHHH
ISSVIDQVYRHCGQKETVIFCDRIMALGFFNAFKAGISFGKDDMVVPASKWKIVDTTRTL
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEHHHHHH
AKDFEQQYNDGLITHGEKYNKVVDAWSKATEEIAKEMMKEISAVRKNASGAETQVNSIYM
HHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCEEEE
MAHSGARGSPAQMRQLAGMRGLMAKPSGEIIETPIISNFKEGLSVLEYFNSTHGARKGLA
EEECCCCCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHCCHHHCCHH
DTALKTANSGYLTRRLVDVAQDCIITQDDCGTSLGIKMRAIIDAGTVVASLGSRILGRTA
HHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCC
GEDVRDPQTNEVIVKKGQLMEERDVEAIHQAGVQEVKIRSALTCELVNGICGKCYGRDLA
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RGTPVNHGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQINEQSVIESNFEGKVVIKNKAI
CCCCCCCCCEEEEEEHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHCCCCCEEEEECCHH
ARNGENHSVAMVRNMVVAIVDPDGTERATHRIQYGARMHVDEGDTVKRGQRIAEWDPYSR
HCCCCCCHHHEEECEEEEEECCCCCHHHHHHHHCCCEEECCCCCHHHHCCCCCCCCCCCC
PVLTEVEGTIDFEDLVEDQSISETLDESTGIAKRIVIDWRSTRGGADLRPAIVVKGKDGK
CEEECCCCCCCHHHHHCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCEEEEECCCCC
VLKLARGGDARYMLSVDAILSVDVGAKVKPGDILARISTESAKTRDITGGLPRVAELFEA
EEEEEECCCCEEEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHC
RKPKDAAIIAEIAGTIRFGRDYKNKRRISIEPMDSEEEAREYLIPKGKHIHLQDGDIVEK
CCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHCCCCCCEEEECCCCEEEC
GDFIVEGNPAPHDILAIKGIEELAAYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEI
CCEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHCCC
TDQGETDMISGEQIDKIEFDQLNAKARDEGKKIATGTPVLLGITKASLQTRSFFSAASFQ
CCCCCCCCCCCCCCCCCCHHHCCCCHHHCCCEEECCCCEEEEEEHHHHHHHHHHHHHHHH
ETTRVLTEAAVNGKVDPLEGLKENVIVGRLIPAGTGASMAKLREVAMKRDRMILDEREKQ
HHHHHHHHHHHCCCCCHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
ATIVPPAAPEAEPLALPPVE
CEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA