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The map label for this gene is plp [H]

Identifier: 86749346

GI number: 86749346

Start: 2539853

End: 2540905

Strand: Direct

Name: plp [H]

Synonym: RPB_2226

Alternate gene names: 86749346

Gene position: 2539853-2540905 (Clockwise)

Preceding gene: 86749345

Following gene: 86749347

Centisome position: 47.64

GC content: 65.81

Gene sequence:

>1053_bases
ATGAGTAACAGCATCGTCGATCGCATCCGACAGGCGGCACTTGTCGGCGTCGCGACGCTGGTCCCCTTGGTTGCGGTAGC
CCAGACTGCGCCGAATCCGCCCGTGCAGAGAGCTCCGCAGGCTGCACCGCGGTCGGCCAAACAGGAACCGTCGGCGACTC
AGGCGGCCGCGCCGACGGCGACGACGAGGCCCGCTCGGGCGGCCGAAAGAATCCCGGATACGCGAAAGGCCGACGACATC
ATCGCGCGTGTCGGATCGACCAACATCTCCGCCGAGGAAATCCGCGGCTACGTCGCCGCCCTCGGCGAGCGCGATCTGGC
GGCGCTGCGTCAGGATCCGAACCTGCTCAGCCAGGCGGTGCGGATGATGCTGGCCAATCGCCTGGTGATGCAGGAAATCG
CCGCCAAGAAGTGGGATCAGCAGCCGAGTGTCGCCGAGAAGCTCGATCGGGTCCGCGAGAGCGCCGCGGTCGAATTGTAT
CTGCAGACGGTGTCGACACCGCCGGAGAGGTTCCCGAGCGAAGACGATCTGCAGAGAGTCTACGACGCCAACCGCGCCGC
GCTGCTGATGCCGCGCCAGTTCGAACTGGCGCAGATCTTCGTGGCGTTGCCGAAGGACGCCGACAAGGCCGCGGAGGACA
AGGCGAAGAAGAGCGTCGAGGATATCCAACGCAAGTTGAAGGCGCCCGGCGTAGATTTCGCGGCGGTGGCGGCCGAGGCG
GGCAACGCCAATGGCGGCGCGTTGGGCTGGGTGGCCGAGAGCCAGATCAGGCCGGAAATTCGCGCCAAGGTGATGGAACT
GTCCAAGAACGCCGTGTCGGATCCGATCAAGCTCGATGACGGCTGGCACTTCGTCAAGGTGCTGGACACCAAGGCTCCCT
ACACGCGGACCCTGCCGGAAGTTCGCGACGGGCTGATCGCTCAGATCCGGACAGAACGCGCCGCCGCTTTGCGCCGGGCG
TATCTCGCCGAGTTGTTGAAGCAGCAGCCTCCGGTGATCAACGAACTCGCCTTGGCGGGAATGCTGAACGAGCGTAGCCC
GGCGGCGCGCTAA

Upstream 100 bases:

>100_bases
CAATTGTCGCGCAGGAGTCGGTGCTCGGATTCAGACGCGTGGAAATCCAGAACAGCATTCAAGAGACCGGCGATAAATTT
CTCGATCAGAAGGTGAGCCC

Downstream 100 bases:

>100_bases
TCGAAGTCCGGAGCCACCGGCCCGGCGCCGCCATGTCCGATTTGCAATTGGAGTATTCTCATGTCCGACACCCTCATCAG
CAAGCTCGATCTTGATGGCT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase plp; Rotamase plp [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSNSIVDRIRQAALVGVATLVPLVAVAQTAPNPPVQRAPQAAPRSAKQEPSATQAAAPTATTRPARAAERIPDTRKADDI
IARVGSTNISAEEIRGYVAALGERDLAALRQDPNLLSQAVRMMLANRLVMQEIAAKKWDQQPSVAEKLDRVRESAAVELY
LQTVSTPPERFPSEDDLQRVYDANRAALLMPRQFELAQIFVALPKDADKAAEDKAKKSVEDIQRKLKAPGVDFAAVAAEA
GNANGGALGWVAESQIRPEIRAKVMELSKNAVSDPIKLDDGWHFVKVLDTKAPYTRTLPEVRDGLIAQIRTERAAALRRA
YLAELLKQQPPVINELALAGMLNERSPAAR

Sequences:

>Translated_350_residues
MSNSIVDRIRQAALVGVATLVPLVAVAQTAPNPPVQRAPQAAPRSAKQEPSATQAAAPTATTRPARAAERIPDTRKADDI
IARVGSTNISAEEIRGYVAALGERDLAALRQDPNLLSQAVRMMLANRLVMQEIAAKKWDQQPSVAEKLDRVRESAAVELY
LQTVSTPPERFPSEDDLQRVYDANRAALLMPRQFELAQIFVALPKDADKAAEDKAKKSVEDIQRKLKAPGVDFAAVAAEA
GNANGGALGWVAESQIRPEIRAKVMELSKNAVSDPIKLDDGWHFVKVLDTKAPYTRTLPEVRDGLIAQIRTERAAALRRA
YLAELLKQQPPVINELALAGMLNERSPAAR
>Mature_349_residues
SNSIVDRIRQAALVGVATLVPLVAVAQTAPNPPVQRAPQAAPRSAKQEPSATQAAAPTATTRPARAAERIPDTRKADDII
ARVGSTNISAEEIRGYVAALGERDLAALRQDPNLLSQAVRMMLANRLVMQEIAAKKWDQQPSVAEKLDRVRESAAVELYL
QTVSTPPERFPSEDDLQRVYDANRAALLMPRQFELAQIFVALPKDADKAAEDKAKKSVEDIQRKLKAPGVDFAAVAAEAG
NANGGALGWVAESQIRPEIRAKVMELSKNAVSDPIKLDDGWHFVKVLDTKAPYTRTLPEVRDGLIAQIRTERAAALRRAY
LAELLKQQPPVINELALAGMLNERSPAAR

Specific function: Ppiases Accelerate The Folding Of Proteins. Seems To Be Involved In The Folding Of Outer Membrane Proteins. Its Preference At The P1 Position Of The Peptide Substrate Is Glu > Leu > Ala > His > Val > Phe > Ile > Gly > Lys > Thr. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 38045; Mature: 37914

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSIVDRIRQAALVGVATLVPLVAVAQTAPNPPVQRAPQAAPRSAKQEPSATQAAAPTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCHHHCCCCC
TTRPARAAERIPDTRKADDIIARVGSTNISAEEIRGYVAALGERDLAALRQDPNLLSQAV
CCCHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHH
RMMLANRLVMQEIAAKKWDQQPSVAEKLDRVRESAAVELYLQTVSTPPERFPSEDDLQRV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHH
YDANRAALLMPRQFELAQIFVALPKDADKAAEDKAKKSVEDIQRKLKAPGVDFAAVAAEA
HCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
GNANGGALGWVAESQIRPEIRAKVMELSKNAVSDPIKLDDGWHFVKVLDTKAPYTRTLPE
CCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHCCCCCEECCCEEEEEEECCCCCCHHCCHH
VRDGLIAQIRTERAAALRRAYLAELLKQQPPVINELALAGMLNERSPAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SNSIVDRIRQAALVGVATLVPLVAVAQTAPNPPVQRAPQAAPRSAKQEPSATQAAAPTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCHHHCCCCC
TTRPARAAERIPDTRKADDIIARVGSTNISAEEIRGYVAALGERDLAALRQDPNLLSQAV
CCCHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHH
RMMLANRLVMQEIAAKKWDQQPSVAEKLDRVRESAAVELYLQTVSTPPERFPSEDDLQRV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHH
YDANRAALLMPRQFELAQIFVALPKDADKAAEDKAKKSVEDIQRKLKAPGVDFAAVAAEA
HCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
GNANGGALGWVAESQIRPEIRAKVMELSKNAVSDPIKLDDGWHFVKVLDTKAPYTRTLPE
CCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHCCCCCEECCCEEEEEEECCCCCCHHCCHH
VRDGLIAQIRTERAAALRRAYLAELLKQQPPVINELALAGMLNERSPAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA