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The map label for this gene is acoC [H]

Identifier: 86749255

GI number: 86749255

Start: 2426445

End: 2427197

Strand: Direct

Name: acoC [H]

Synonym: RPB_2134

Alternate gene names: 86749255

Gene position: 2426445-2427197 (Clockwise)

Preceding gene: 86749254

Following gene: 86749256

Centisome position: 45.51

GC content: 69.59

Gene sequence:

>753_bases
ATGCCGAGCTTTGATCACGGCGGAGTCACTATCGCGTATCTCGACGACGGCGAGGGCGATCCGATCGTGCTCGTGCACGG
CTTCGCGTCGAACAAGAACGTCAACTGGGTGTATCCGTCGTGGCTGTCGGAGCTGAAGCGCGCCGGGCGTCGCGTCGTCG
CGCTCGACAATCGCGGCCACGGCGAATCGTCCAAGCTGTACGATCCCGCCGATTACGGGCTGACCACGATGGCCGGCGAC
GTGATCGCGCTGATGGATCATCTGGCGATCGATCGCGCCGATATCATGGGCTACTCGCTCGGCGGCCGCATCACCGCGAC
GCTGGCGCGGCGGCATCCCGAGCGCGTCCGCGCGGCGATCCTCGGCGGTATCGGCAGCGGCCTGGTGGTCGGCGGCGGGC
CGGGCGAGACCGTGGCGCTGGCGCTCGAGGCGCCGTCGCTCGACGACGTCAGCGATCCGGTCGGCCGCACCTTCCGCGCC
TTCGCCGATCAGACCCGCTCCGATCGCAAGGCGCTGGCCGCCTGCCTGCGCGGCTCGCGGACGCTGATGAGCGAAGACGA
GGTCGCGCAGATCGCGGTGCCGGTGCTGATCGCGGTCGGCACCGTCGACGACGTCGCCGGCTCGGCGCATCAGCTCAGCG
GCATGATCCCCGGCTCCGAAGTGCTCGACATCCCGCGCCGCGACCACATGCGCGCGGTCGGCGATCGCGTTTTCAAGGAA
GGCGTCGTCGATTTTCTCGGGCGCCGGCCGTGA

Upstream 100 bases:

>100_bases
CTGTCGGTTTCGTAGTTGTCGGGCGACGTCGTGACTCTCTATCCTGCCGCTGTCCACACGACGACCTCACCATCTCCTTC
AACAACTCATCGGACGGTCG

Downstream 100 bases:

>100_bases
CCGGCCGGGCGGTGGCTTCGCCGGCAGCTTGAACCCGGCGATGCGCTCCCCATGTCGAGTGTCGCAACACCGACAAGGGC
AGCCGCCGGCCGGATGAATG

Product: alpha/beta hydrolase fold

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MPSFDHGGVTIAYLDDGEGDPIVLVHGFASNKNVNWVYPSWLSELKRAGRRVVALDNRGHGESSKLYDPADYGLTTMAGD
VIALMDHLAIDRADIMGYSLGGRITATLARRHPERVRAAILGGIGSGLVVGGGPGETVALALEAPSLDDVSDPVGRTFRA
FADQTRSDRKALAACLRGSRTLMSEDEVAQIAVPVLIAVGTVDDVAGSAHQLSGMIPGSEVLDIPRRDHMRAVGDRVFKE
GVVDFLGRRP

Sequences:

>Translated_250_residues
MPSFDHGGVTIAYLDDGEGDPIVLVHGFASNKNVNWVYPSWLSELKRAGRRVVALDNRGHGESSKLYDPADYGLTTMAGD
VIALMDHLAIDRADIMGYSLGGRITATLARRHPERVRAAILGGIGSGLVVGGGPGETVALALEAPSLDDVSDPVGRTFRA
FADQTRSDRKALAACLRGSRTLMSEDEVAQIAVPVLIAVGTVDDVAGSAHQLSGMIPGSEVLDIPRRDHMRAVGDRVFKE
GVVDFLGRRP
>Mature_249_residues
PSFDHGGVTIAYLDDGEGDPIVLVHGFASNKNVNWVYPSWLSELKRAGRRVVALDNRGHGESSKLYDPADYGLTTMAGDV
IALMDHLAIDRADIMGYSLGGRITATLARRHPERVRAAILGGIGSGLVVGGGPGETVALALEAPSLDDVSDPVGRTFRAF
ADQTRSDRKALAACLRGSRTLMSEDEVAQIAVPVLIAVGTVDDVAGSAHQLSGMIPGSEVLDIPRRDHMRAVGDRVFKEG
VVDFLGRRP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=119, Percent_Identity=31.9327731092437, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 26566; Mature: 26435

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSFDHGGVTIAYLDDGEGDPIVLVHGFASNKNVNWVYPSWLSELKRAGRRVVALDNRGH
CCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCEECHHHHHHHHHCCCEEEEECCCCC
GESSKLYDPADYGLTTMAGDVIALMDHLAIDRADIMGYSLGGRITATLARRHPERVRAAI
CCCCCCCCCHHCCHHHHHHHHHHHHHHHHHCHHHHCEECCCCCHHHHHHHHCHHHHHHHH
LGGIGSGLVVGGGPGETVALALEAPSLDDVSDPVGRTFRAFADQTRSDRKALAACLRGSR
HHCCCCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCC
TLMSEDEVAQIAVPVLIAVGTVDDVAGSAHQLSGMIPGSEVLDIPRRDHMRAVGDRVFKE
CCCCCHHHHHHHHHHHHEECCHHHHCCCHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHH
GVVDFLGRRP
HHHHHHCCCC
>Mature Secondary Structure 
PSFDHGGVTIAYLDDGEGDPIVLVHGFASNKNVNWVYPSWLSELKRAGRRVVALDNRGH
CCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCEECHHHHHHHHHCCCEEEEECCCCC
GESSKLYDPADYGLTTMAGDVIALMDHLAIDRADIMGYSLGGRITATLARRHPERVRAAI
CCCCCCCCCHHCCHHHHHHHHHHHHHHHHHCHHHHCEECCCCCHHHHHHHHCHHHHHHHH
LGGIGSGLVVGGGPGETVALALEAPSLDDVSDPVGRTFRAFADQTRSDRKALAACLRGSR
HHCCCCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCC
TLMSEDEVAQIAVPVLIAVGTVDDVAGSAHQLSGMIPGSEVLDIPRRDHMRAVGDRVFKE
CCCCCHHHHHHHHHHHHEECCHHHHCCCHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHH
GVVDFLGRRP
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]