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The map label for this gene is murG

Identifier: 86749117

GI number: 86749117

Start: 2265952

End: 2267052

Strand: Direct

Name: murG

Synonym: RPB_1994

Alternate gene names: 86749117

Gene position: 2265952-2267052 (Clockwise)

Preceding gene: 86749116

Following gene: 86749118

Centisome position: 42.5

GC content: 72.21

Gene sequence:

>1101_bases
ATGAGCGACGCGCCCCTCATCCTTCTCGCGGCGGGCGGCACCGGCGGGCATCTGTTCCCCGCCGAGGCGCTCGGCGTGGT
GCTGATGAAGCGCGGCCTGCGCGTGCGCCTCGTCACCGACAGCCGCGCGATGCGCTACAGCGGGTTGTTCTCCGCCGACA
TGATCGACGTGGTGCCGAGCGAGACGGTGCGCGGCAGGACGCCGTGGGCGCTGGCCCGGACCGGGCTGATGCTCGGTGCC
GGAACCGCGAAGGCGCTCGCGCTGATGCTGCGGCTGAAGCCCGCCGCAGTGGTCGGCTTCGGCGGCTATCCGACGCTGCC
GCCCTTGTTCGCGGCGCGGGCGTTGCGGATTCCGACGCTGATTCACGATTCCAATGCGGTGATGGGCCGCGCCAACCGGC
TGCTGTCGAAGGGTGTCACGGCGATCGCGACCTCATTGCCCGGCGTGCTCGACCGCGATCCGACGCTTTCCGCCAAGACC
ACCACCACCGGCACGCCGATGCGCCCGGCAATCCTCGCGGCCGCCGCGGTGCCGTTCGCGCCGCTCGCCGCGGAGGGGCC
GCTGCGGCTGCTGGTGGTCGGCGGCAGCCAGGGCGCGCGGGTGATGGCCGACATCGTGCCCGGCGCGATCGAGCAGCTCG
ATCCGGCGCTGCAGCCGCGGCTGGTGCTGACCCAGCAGGTCCGCGAGGAGGACATGGCGCGGGTCCGCGCCGTCTACGAC
CGGCTGAAGATCACCTGCGAGCTCGCTCCGTTCTTCAACGATCTGCCGGCGCGGCTGGCCGCCAGCCAATTGGTGGTATC
ACGTTCCGGTGCTGGCACCGTCGCCGAACTCGCCGCGATCGGCCGGCCGTCGATCCTGGTGCCGCTGCCCGGTGCGCTGG
ATCAGGACCAGTTCGCCAATGCCGGCGTGCTCGCCGACGCCGGCGGCGCGATCCGGATCGTGCAGGCCGACTTCACCCCC
GAGCGGCTCGCCGACGAGATCGCCGCGCTGGCCGCCGATCCGCAGAAACTCACCGCGATGGTCACCGCCGCCCGCACCGT
CGGCCGGCTCGATGCCGCGGACCGGCTGGCGGATCTGGTCGTCAAGGTGGCGAACATCTGA

Upstream 100 bases:

>100_bases
CTTGCCTATGGCGTCGGCATGATGCTGGCGTTGACCCGGCTGCGGCCGAAGACCGAGGTCAATGCCATGGGTGCCGCGGC
TGCGGGCTACGCGTGACGCC

Downstream 100 bases:

>100_bases
GATGGTTGTGCGATGCCCGATCTGCTGATCCATTCGGTTGCTGAATTTTCCGACCTGATCCTCGAGGCCCTGACCCTGGC
CGAAGCCCGCACCATCGCGG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSDAPLILLAAGGTGGHLFPAEALGVVLMKRGLRVRLVTDSRAMRYSGLFSADMIDVVPSETVRGRTPWALARTGLMLGA
GTAKALALMLRLKPAAVVGFGGYPTLPPLFAARALRIPTLIHDSNAVMGRANRLLSKGVTAIATSLPGVLDRDPTLSAKT
TTTGTPMRPAILAAAAVPFAPLAAEGPLRLLVVGGSQGARVMADIVPGAIEQLDPALQPRLVLTQQVREEDMARVRAVYD
RLKITCELAPFFNDLPARLAASQLVVSRSGAGTVAELAAIGRPSILVPLPGALDQDQFANAGVLADAGGAIRIVQADFTP
ERLADEIAALAADPQKLTAMVTAARTVGRLDAADRLADLVVKVANI

Sequences:

>Translated_366_residues
MSDAPLILLAAGGTGGHLFPAEALGVVLMKRGLRVRLVTDSRAMRYSGLFSADMIDVVPSETVRGRTPWALARTGLMLGA
GTAKALALMLRLKPAAVVGFGGYPTLPPLFAARALRIPTLIHDSNAVMGRANRLLSKGVTAIATSLPGVLDRDPTLSAKT
TTTGTPMRPAILAAAAVPFAPLAAEGPLRLLVVGGSQGARVMADIVPGAIEQLDPALQPRLVLTQQVREEDMARVRAVYD
RLKITCELAPFFNDLPARLAASQLVVSRSGAGTVAELAAIGRPSILVPLPGALDQDQFANAGVLADAGGAIRIVQADFTP
ERLADEIAALAADPQKLTAMVTAARTVGRLDAADRLADLVVKVANI
>Mature_365_residues
SDAPLILLAAGGTGGHLFPAEALGVVLMKRGLRVRLVTDSRAMRYSGLFSADMIDVVPSETVRGRTPWALARTGLMLGAG
TAKALALMLRLKPAAVVGFGGYPTLPPLFAARALRIPTLIHDSNAVMGRANRLLSKGVTAIATSLPGVLDRDPTLSAKTT
TTGTPMRPAILAAAAVPFAPLAAEGPLRLLVVGGSQGARVMADIVPGAIEQLDPALQPRLVLTQQVREEDMARVRAVYDR
LKITCELAPFFNDLPARLAASQLVVSRSGAGTVAELAAIGRPSILVPLPGALDQDQFANAGVLADAGGAIRIVQADFTPE
RLADEIAALAADPQKLTAMVTAARTVGRLDAADRLADLVVKVANI

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=367, Percent_Identity=32.6975476839237, Blast_Score=150, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_RHOP2 (Q2IYK8)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_485613.1
- ProteinModelPortal:   Q2IYK8
- SMR:   Q2IYK8
- STRING:   Q2IYK8
- GeneID:   3909500
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_1994
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   RPAL316058:RPB_1994-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38025; Mature: 37894

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAPLILLAAGGTGGHLFPAEALGVVLMKRGLRVRLVTDSRAMRYSGLFSADMIDVVPS
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCCCHHHHCCC
ETVRGRTPWALARTGLMLGAGTAKALALMLRLKPAAVVGFGGYPTLPPLFAARALRIPTL
CCCCCCCCHHHHHHCCEEECCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCEE
IHDSNAVMGRANRLLSKGVTAIATSLPGVLDRDPTLSAKTTTTGTPMRPAILAAAAVPFA
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
PLAAEGPLRLLVVGGSQGARVMADIVPGAIEQLDPALQPRLVLTQQVREEDMARVRAVYD
CCCCCCCEEEEEEECCCCCCHHHHHCCHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHH
RLKITCELAPFFNDLPARLAASQLVVSRSGAGTVAELAAIGRPSILVPLPGALDQDQFAN
HHEEEEEECCHHHHHHHHHHHHHHHEECCCCCHHHHHHHCCCCEEEEECCCCCCHHHHCC
AGVLADAGGAIRIVQADFTPERLADEIAALAADPQKLTAMVTAARTVGRLDAADRLADLV
CCEEEECCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKVANI
HHHHCC
>Mature Secondary Structure 
SDAPLILLAAGGTGGHLFPAEALGVVLMKRGLRVRLVTDSRAMRYSGLFSADMIDVVPS
CCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCCCHHHHCCC
ETVRGRTPWALARTGLMLGAGTAKALALMLRLKPAAVVGFGGYPTLPPLFAARALRIPTL
CCCCCCCCHHHHHHCCEEECCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCEE
IHDSNAVMGRANRLLSKGVTAIATSLPGVLDRDPTLSAKTTTTGTPMRPAILAAAAVPFA
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
PLAAEGPLRLLVVGGSQGARVMADIVPGAIEQLDPALQPRLVLTQQVREEDMARVRAVYD
CCCCCCCEEEEEEECCCCCCHHHHHCCHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHH
RLKITCELAPFFNDLPARLAASQLVVSRSGAGTVAELAAIGRPSILVPLPGALDQDQFAN
HHEEEEEECCHHHHHHHHHHHHHHHEECCCCCHHHHHHHCCCCEEEEECCCCCCHHHHCC
AGVLADAGGAIRIVQADFTPERLADEIAALAADPQKLTAMVTAARTVGRLDAADRLADLV
CCEEEECCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKVANI
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA