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The map label for this gene is ftsW [H]

Identifier: 86749116

GI number: 86749116

Start: 2264802

End: 2265947

Strand: Direct

Name: ftsW [H]

Synonym: RPB_1993

Alternate gene names: 86749116

Gene position: 2264802-2265947 (Clockwise)

Preceding gene: 86749115

Following gene: 86749117

Centisome position: 42.48

GC content: 66.23

Gene sequence:

>1146_bases
ATGATTTCCCGTGAGCAACGCACCCCGTTCAGCGAATGGTGGTGGACCATCGACCGCGTGCTGCTGGTGGCGCTGATCGC
GCTGATGCTGGCGGGCGTCATCCTGTCGCTGGCGGCGTCGCCGCCGGTCGCGACGCGGATCGGGCTCGACCCGTTCCATT
TCTTCAACCGCCATGTGCTGTTCCTGGCGCCGTCGCTGATCGTGCTGATCGGGGTGTCGTTCCTGTCGCCGCGGCAGATC
CGGCGTGCCGCGCTGATCGTGTTCGCGCTCAGCATCGTGCTGATCGTCGCGACCCTGTTGTTCGGCCCGGAGGTGAAGGG
CTCCCGGCGCTGGATCACGCTGCTCGGCCTCAATATTCAGGCCTCCGAAATCGCCAAACCGTCCTTCGTGGTGCTGGCGG
CGTGGCTGTTCTCGGAAGCGGCGCGGCGGCCGGAAATGCCGGCGACCTCGATGTCGCTGGCGCTGCTGCTGACGCTGGTG
TCGCTGCTGGTGATGGAGCCGGATTTCGGCCAGACCATGCTGGTGCTGATGGTGTGGGGCGCGCTGTTCTTCATCGCGGG
GATGCGGATCGTCTGGGTGTTCGGGCTGGCCGGCGTCGCCGCAGGCGGCCTGTTCGCCGCCTATCTGTTCGTCCCGCACG
TCGCCGGCCGGATCAAGCGGTTCATGAACCCGGCATCGGGCGATACTTTCCAGGTCGACATGGCGAGCGAGGCGTTCAGC
AACGGCGGCTGGTTCGGTCTCGGGCCCGGCGAGGGCATCGCCAAGCGCAGCCTGCCGGACAGTCACACCGACTTCGTGTT
TGCCGTGGCCGGCGAGGAATTCGGCATCATCCTGTGCCTGGCGCTGCTGGCGCTGTTCACCTTCATCGTGATGCGCACGC
TGTCGCGCGCCTACAAGTCGGACGATCTGTTCGCGCGCTTCGCCGCGTCCGGGCTGGCCATCCTGTTCGGCATCCAGGCC
GCGATCAACATGTCGGTCAATCTGCAACTGATCCCGGCCAAGGGCATGACGCTGCCGTTCATCTCCTATGGCGGCTCGTC
GATGGTGTCACTTGCCTATGGCGTCGGCATGATGCTGGCGTTGACCCGGCTGCGGCCGAAGACCGAGGTCAATGCCATGG
GTGCCGCGGCTGCGGGCTACGCGTGA

Upstream 100 bases:

>100_bases
GGCAGGTCGGCGTTCACAACCTCAACTCTTCCCCTTTCCATTAACTTTCTGGCAACCACGACGGCGCACCAATAAGCCGA
CCTCTGGCCCAGGATCGCCG

Downstream 100 bases:

>100_bases
CGCCATGAGCGACGCGCCCCTCATCCTTCTCGCGGCGGGCGGCACCGGCGGGCATCTGTTCCCCGCCGAGGCGCTCGGCG
TGGTGCTGATGAAGCGCGGC

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MISREQRTPFSEWWWTIDRVLLVALIALMLAGVILSLAASPPVATRIGLDPFHFFNRHVLFLAPSLIVLIGVSFLSPRQI
RRAALIVFALSIVLIVATLLFGPEVKGSRRWITLLGLNIQASEIAKPSFVVLAAWLFSEAARRPEMPATSMSLALLLTLV
SLLVMEPDFGQTMLVLMVWGALFFIAGMRIVWVFGLAGVAAGGLFAAYLFVPHVAGRIKRFMNPASGDTFQVDMASEAFS
NGGWFGLGPGEGIAKRSLPDSHTDFVFAVAGEEFGIILCLALLALFTFIVMRTLSRAYKSDDLFARFAASGLAILFGIQA
AINMSVNLQLIPAKGMTLPFISYGGSSMVSLAYGVGMMLALTRLRPKTEVNAMGAAAAGYA

Sequences:

>Translated_381_residues
MISREQRTPFSEWWWTIDRVLLVALIALMLAGVILSLAASPPVATRIGLDPFHFFNRHVLFLAPSLIVLIGVSFLSPRQI
RRAALIVFALSIVLIVATLLFGPEVKGSRRWITLLGLNIQASEIAKPSFVVLAAWLFSEAARRPEMPATSMSLALLLTLV
SLLVMEPDFGQTMLVLMVWGALFFIAGMRIVWVFGLAGVAAGGLFAAYLFVPHVAGRIKRFMNPASGDTFQVDMASEAFS
NGGWFGLGPGEGIAKRSLPDSHTDFVFAVAGEEFGIILCLALLALFTFIVMRTLSRAYKSDDLFARFAASGLAILFGIQA
AINMSVNLQLIPAKGMTLPFISYGGSSMVSLAYGVGMMLALTRLRPKTEVNAMGAAAAGYA
>Mature_381_residues
MISREQRTPFSEWWWTIDRVLLVALIALMLAGVILSLAASPPVATRIGLDPFHFFNRHVLFLAPSLIVLIGVSFLSPRQI
RRAALIVFALSIVLIVATLLFGPEVKGSRRWITLLGLNIQASEIAKPSFVVLAAWLFSEAARRPEMPATSMSLALLLTLV
SLLVMEPDFGQTMLVLMVWGALFFIAGMRIVWVFGLAGVAAGGLFAAYLFVPHVAGRIKRFMNPASGDTFQVDMASEAFS
NGGWFGLGPGEGIAKRSLPDSHTDFVFAVAGEEFGIILCLALLALFTFIVMRTLSRAYKSDDLFARFAASGLAILFGIQA
AINMSVNLQLIPAKGMTLPFISYGGSSMVSLAYGVGMMLALTRLRPKTEVNAMGAAAAGYA

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=361, Percent_Identity=32.6869806094183, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786853, Length=322, Percent_Identity=29.8136645962733, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41113; Mature: 41113

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISREQRTPFSEWWWTIDRVLLVALIALMLAGVILSLAASPPVATRIGLDPFHFFNRHVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHCCHHH
FLAPSLIVLIGVSFLSPRQIRRAALIVFALSIVLIVATLLFGPEVKGSRRWITLLGLNIQ
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
ASEIAKPSFVVLAAWLFSEAARRPEMPATSMSLALLLTLVSLLVMEPDFGQTMLVLMVWG
HHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ALFFIAGMRIVWVFGLAGVAAGGLFAAYLFVPHVAGRIKRFMNPASGDTFQVDMASEAFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHC
NGGWFGLGPGEGIAKRSLPDSHTDFVFAVAGEEFGIILCLALLALFTFIVMRTLSRAYKS
CCCEEECCCCCCCHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDLFARFAASGLAILFGIQAAINMSVNLQLIPAKGMTLPFISYGGSSMVSLAYGVGMMLA
CHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCEECEEECCCCHHHHHHHHHHHHHH
LTRLRPKTEVNAMGAAAAGYA
HHHCCCCCHHHHCCCHHCCCC
>Mature Secondary Structure
MISREQRTPFSEWWWTIDRVLLVALIALMLAGVILSLAASPPVATRIGLDPFHFFNRHVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHCCHHH
FLAPSLIVLIGVSFLSPRQIRRAALIVFALSIVLIVATLLFGPEVKGSRRWITLLGLNIQ
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
ASEIAKPSFVVLAAWLFSEAARRPEMPATSMSLALLLTLVSLLVMEPDFGQTMLVLMVWG
HHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ALFFIAGMRIVWVFGLAGVAAGGLFAAYLFVPHVAGRIKRFMNPASGDTFQVDMASEAFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHC
NGGWFGLGPGEGIAKRSLPDSHTDFVFAVAGEEFGIILCLALLALFTFIVMRTLSRAYKS
CCCEEECCCCCCCHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDLFARFAASGLAILFGIQAAINMSVNLQLIPAKGMTLPFISYGGSSMVSLAYGVGMMLA
CHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCEECEEECCCCHHHHHHHHHHHHHH
LTRLRPKTEVNAMGAAAAGYA
HHHCCCCCHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]