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The map label for this gene is 86749095

Identifier: 86749095

GI number: 86749095

Start: 2238228

End: 2239280

Strand: Direct

Name: 86749095

Synonym: RPB_1972

Alternate gene names: NA

Gene position: 2238228-2239280 (Clockwise)

Preceding gene: 86749094

Following gene: 86749098

Centisome position: 41.98

GC content: 66.29

Gene sequence:

>1053_bases
ATGTCCACCTTCGAACGCTATCTGACGCTGTGGGTCGCGCTGTGCATCGCCGTCGGCATCGGGCTCGGCCATGTCGTGCC
CGGCCTGTTCCAGGCGGTCGCCGCCGCCGAGATCGCCAAGGTCAATCTGCCGGTGGCGGTGCTGATCTGGCTGATGATCA
TTCCGATGCTGGTGAAGATCGATTTCGCCGCGCTGGCGCGGGTGCGCGAGCATTGGCGCGGCATCGGCGTGACGCTGTTC
ATTAACTGGGCGGTGAAGCCGTTCTCGATGGCGGCGCTGGCCTGGCTGTTCATCGGCTGGCTGTTCAGGGATCATCTGCC
GGCCGATCAGATCAATTCCTACATCGCCGGGCTGATCATTCTGGCCGCGGCGCCGTGCACCGCGATGGTGTTCGTGTGGT
CGAACCTGATCAAAGGCGAGCCGCATTTCACGCTGAGCCAGGTAGCGCTGAACGACACCATCATGGTGTTCGCCTTCGCG
CCGATCGTCGGCCTGCTGCTCGGCCTGTCGGCGATCACCGTGCCGTGGGACACGCTGATGATCTCGGTGGCGCTGTACAT
CGTGGTGCCGGTGATCATCGCGCAAATGCTGCGGCGGCGGGTGCTGGCGGCCGGCGGCGAGGCGGGATTGCAGCGCTTGC
TCGGCGCGGTTCAGCCGCTGTCGCTGGTCGCCTTGCTGGCGACGCTGGTGCTGCTGTTCGGCTTCCAGGGCGAGCAGATC
ATCCGGCAGCCGCTGGTGATCGCGCTGCTCGCGGTGCCGATCCTGATCCAGGTGTATTTCAACGCCGGGCTCGCTTATCT
GCTCAATCGCCTGAGCGGCGAGCAGCATTGCGTCGCGGGTCCCTCGGCGCTGATCGGCGCCAGCAACTTCTTCGAACTCG
CGGTGGCCGCCGCGATCAGCCTGTTCGGCTTCGAATCCGGCGCGGCGCTGGCCACCGTGGTCGGCGTGCTGATCGAGGTG
CCGGTGATGCTGACGGTGGTGTGGATCGTCAACCGCTCCAAGGGCTGGTACGAGGGCGAGGCGCGCGCCGCCGTCACGAC
CCGGCCGGGTTAG

Upstream 100 bases:

>100_bases
TTCACGGGGATGACGGCGGTGGATTGGGTCGCTTCGTTTGCAAGACAAGACGCTTTTTCGAGCGGCGCGACGCGGCGCGA
AGTGATCAAAGAGGTCCTCA

Downstream 100 bases:

>100_bases
CCGGCCCGCAGCGTCAGCCCGGTCGCGGCCTCGAGCTCGGCGATCGCCTGATCGGCGCTGACCACCTTGATCGTGGTCAT
CCCCAACTCGCGCGCCGGCT

Product: bile acid:sodium symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSTFERYLTLWVALCIAVGIGLGHVVPGLFQAVAAAEIAKVNLPVAVLIWLMIIPMLVKIDFAALARVREHWRGIGVTLF
INWAVKPFSMAALAWLFIGWLFRDHLPADQINSYIAGLIILAAAPCTAMVFVWSNLIKGEPHFTLSQVALNDTIMVFAFA
PIVGLLLGLSAITVPWDTLMISVALYIVVPVIIAQMLRRRVLAAGGEAGLQRLLGAVQPLSLVALLATLVLLFGFQGEQI
IRQPLVIALLAVPILIQVYFNAGLAYLLNRLSGEQHCVAGPSALIGASNFFELAVAAAISLFGFESGAALATVVGVLIEV
PVMLTVVWIVNRSKGWYEGEARAAVTTRPG

Sequences:

>Translated_350_residues
MSTFERYLTLWVALCIAVGIGLGHVVPGLFQAVAAAEIAKVNLPVAVLIWLMIIPMLVKIDFAALARVREHWRGIGVTLF
INWAVKPFSMAALAWLFIGWLFRDHLPADQINSYIAGLIILAAAPCTAMVFVWSNLIKGEPHFTLSQVALNDTIMVFAFA
PIVGLLLGLSAITVPWDTLMISVALYIVVPVIIAQMLRRRVLAAGGEAGLQRLLGAVQPLSLVALLATLVLLFGFQGEQI
IRQPLVIALLAVPILIQVYFNAGLAYLLNRLSGEQHCVAGPSALIGASNFFELAVAAAISLFGFESGAALATVVGVLIEV
PVMLTVVWIVNRSKGWYEGEARAAVTTRPG
>Mature_349_residues
STFERYLTLWVALCIAVGIGLGHVVPGLFQAVAAAEIAKVNLPVAVLIWLMIIPMLVKIDFAALARVREHWRGIGVTLFI
NWAVKPFSMAALAWLFIGWLFRDHLPADQINSYIAGLIILAAAPCTAMVFVWSNLIKGEPHFTLSQVALNDTIMVFAFAP
IVGLLLGLSAITVPWDTLMISVALYIVVPVIIAQMLRRRVLAAGGEAGLQRLLGAVQPLSLVALLATLVLLFGFQGEQII
RQPLVIALLAVPILIQVYFNAGLAYLLNRLSGEQHCVAGPSALIGASNFFELAVAAAISLFGFESGAALATVVGVLIEVP
VMLTVVWIVNRSKGWYEGEARAAVTTRPG

Specific function: Unknown

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=347, Percent_Identity=25.0720461095101, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 37613; Mature: 37481

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFERYLTLWVALCIAVGIGLGHVVPGLFQAVAAAEIAKVNLPVAVLIWLMIIPMLVKI
CCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
DFAALARVREHWRGIGVTLFINWAVKPFSMAALAWLFIGWLFRDHLPADQINSYIAGLII
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAAAPCTAMVFVWSNLIKGEPHFTLSQVALNDTIMVFAFAPIVGLLLGLSAITVPWDTLM
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ISVALYIVVPVIIAQMLRRRVLAAGGEAGLQRLLGAVQPLSLVALLATLVLLFGFQGEQI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IRQPLVIALLAVPILIQVYFNAGLAYLLNRLSGEQHCVAGPSALIGASNFFELAVAAAIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHH
LFGFESGAALATVVGVLIEVPVMLTVVWIVNRSKGWYEGEARAAVTTRPG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCC
>Mature Secondary Structure 
STFERYLTLWVALCIAVGIGLGHVVPGLFQAVAAAEIAKVNLPVAVLIWLMIIPMLVKI
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
DFAALARVREHWRGIGVTLFINWAVKPFSMAALAWLFIGWLFRDHLPADQINSYIAGLII
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAAAPCTAMVFVWSNLIKGEPHFTLSQVALNDTIMVFAFAPIVGLLLGLSAITVPWDTLM
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ISVALYIVVPVIIAQMLRRRVLAAGGEAGLQRLLGAVQPLSLVALLATLVLLFGFQGEQI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IRQPLVIALLAVPILIQVYFNAGLAYLLNRLSGEQHCVAGPSALIGASNFFELAVAAAIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHH
LFGFESGAALATVVGVLIEVPVMLTVVWIVNRSKGWYEGEARAAVTTRPG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]