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The map label for this gene is glnII [H]

Identifier: 86748530

GI number: 86748530

Start: 1596276

End: 1597379

Strand: Direct

Name: glnII [H]

Synonym: RPB_1405

Alternate gene names: 86748530

Gene position: 1596276-1597379 (Clockwise)

Preceding gene: 86748528

Following gene: 86748531

Centisome position: 29.94

GC content: 62.95

Gene sequence:

>1104_bases
ATGTCGGCCGCCGGGCGCGGTTCCGTCCGCTTCGGGTTCCCACCCTTTGCACTCAACAGAGAGAACCGCATGACCAAGTA
CAAGCTCGAGTACATCTGGCTCGACGGCTACACGCCGGTGCCGAACCTGCGTGGCAAGACGCAGATCAAGGAATTCGAAA
TCTATCCGACGCTCGAGCAACTGCCGCTGTGGGGCTTCGACGGCTCCTCCACCATGCAGGCCGAGGGCCGCAGCTCGGAT
TGCGTACTGAAGCCGGTCGCGATGTTCCACGACGCCACCCGCAAGAACGGCATTCTGGTGATGTGCGAAGTGATGATGCC
CGACGGCGTCACCCCGCACGCGACCAACACCCGCGCCACCATCCTCGACGATGAAGGCGCCTGGTTCGGCTTCGAGCAGG
AATACTTCTTCTACAAGGACGGCCGCCCGCTCGGTTTCCCGGAAGCCGGTTACCCGGCGCCGCAGGGCCCGTACTACACC
GGCGTCGGCTTCAAGAACGTCGGCAACATCGCGCGCAAGATCGTCGAGGAGCATCTCGACCTCTGCCTCGCCGCCGGCAT
CAACCACGAAGGCATCAACGCCGAAGTGGCGAAGGGCCAGTGGGAATTCCAGATCTTCGGCAAGGGCTCGAAGACCGCCG
CCGACCAGATGTGGATGGCGCGCTACCTGATGCTGCGGCTGTGCGAAAGCTACGGCATCGACATCGAATGGCACTGCAAG
CCGCTCGGCGACACCGACTGGAACGGCTCGGGCATGCACGCCAACTTCTCGACCAAGTACATGCGTGAAGTCGGCGGCAA
GGACTATTTCGAAGCTCTGATGGGGCAGTTCGAAAAGAACCTGCACGACCACATCGCCGTGTACGGTCCGGACAACCACA
TGCGCCTGACCGGCAAGCACGAGACCGCGCCGTGGAACAAGTTCTCCTACGGGGTGGCGGACCGCGGCGCCTCGATCCGC
GTGCCGCATTCCTTCGTCAACAACGGCTACAAGGGCTATCTGGAAGACCGCCGCCCGAACTCGATGGGCGACCCCTACCA
GATCGCGTCGCAGATCCTGAAGACGATTTCGGAAGTCCCCACCTCGAAGGCCGCTGCGGCCTGA

Upstream 100 bases:

>100_bases
GCCGCGCATATTGACGGCAGAACCCAGCGCCGATCACGCCCGCGCGAATTGTCGCAGGCCGGGCGGCATTTGGCATAACA
AATGCTTTCGTGACAGCCGG

Downstream 100 bases:

>100_bases
TCCACCCGTCACCGCGAGCGCCTCCTCCTCCAGGGCGCAAGCACACGGCCCGGACGCAAGTCCGGGCCGTTGTTTTTTGG
AGCAGGCGTCTTGCCGCGCG

Product: glutamate--ammonia ligase

Products: NA

Alternate protein names: Glutamate--ammonia ligase II; Glutamine synthetase II; GSII [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSAAGRGSVRFGFPPFALNRENRMTKYKLEYIWLDGYTPVPNLRGKTQIKEFEIYPTLEQLPLWGFDGSSTMQAEGRSSD
CVLKPVAMFHDATRKNGILVMCEVMMPDGVTPHATNTRATILDDEGAWFGFEQEYFFYKDGRPLGFPEAGYPAPQGPYYT
GVGFKNVGNIARKIVEEHLDLCLAAGINHEGINAEVAKGQWEFQIFGKGSKTAADQMWMARYLMLRLCESYGIDIEWHCK
PLGDTDWNGSGMHANFSTKYMREVGGKDYFEALMGQFEKNLHDHIAVYGPDNHMRLTGKHETAPWNKFSYGVADRGASIR
VPHSFVNNGYKGYLEDRRPNSMGDPYQIASQILKTISEVPTSKAAAA

Sequences:

>Translated_367_residues
MSAAGRGSVRFGFPPFALNRENRMTKYKLEYIWLDGYTPVPNLRGKTQIKEFEIYPTLEQLPLWGFDGSSTMQAEGRSSD
CVLKPVAMFHDATRKNGILVMCEVMMPDGVTPHATNTRATILDDEGAWFGFEQEYFFYKDGRPLGFPEAGYPAPQGPYYT
GVGFKNVGNIARKIVEEHLDLCLAAGINHEGINAEVAKGQWEFQIFGKGSKTAADQMWMARYLMLRLCESYGIDIEWHCK
PLGDTDWNGSGMHANFSTKYMREVGGKDYFEALMGQFEKNLHDHIAVYGPDNHMRLTGKHETAPWNKFSYGVADRGASIR
VPHSFVNNGYKGYLEDRRPNSMGDPYQIASQILKTISEVPTSKAAAA
>Mature_366_residues
SAAGRGSVRFGFPPFALNRENRMTKYKLEYIWLDGYTPVPNLRGKTQIKEFEIYPTLEQLPLWGFDGSSTMQAEGRSSDC
VLKPVAMFHDATRKNGILVMCEVMMPDGVTPHATNTRATILDDEGAWFGFEQEYFFYKDGRPLGFPEAGYPAPQGPYYTG
VGFKNVGNIARKIVEEHLDLCLAAGINHEGINAEVAKGQWEFQIFGKGSKTAADQMWMARYLMLRLCESYGIDIEWHCKP
LGDTDWNGSGMHANFSTKYMREVGGKDYFEALMGQFEKNLHDHIAVYGPDNHMRLTGKHETAPWNKFSYGVADRGASIRV
PHSFVNNGYKGYLEDRRPNSMGDPYQIASQILKTISEVPTSKAAAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI74271826, Length=343, Percent_Identity=44.0233236151604, Blast_Score=260, Evalue=1e-69,
Organism=Homo sapiens, GI74271837, Length=343, Percent_Identity=44.0233236151604, Blast_Score=260, Evalue=1e-69,
Organism=Homo sapiens, GI19923206, Length=343, Percent_Identity=44.0233236151604, Blast_Score=260, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI115532978, Length=343, Percent_Identity=47.5218658892128, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI115532980, Length=343, Percent_Identity=47.5218658892128, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17540008, Length=347, Percent_Identity=45.2449567723343, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17554028, Length=346, Percent_Identity=44.2196531791908, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17538856, Length=346, Percent_Identity=42.485549132948, Blast_Score=253, Evalue=8e-68,
Organism=Caenorhabditis elegans, GI17551038, Length=321, Percent_Identity=39.5638629283489, Blast_Score=211, Evalue=7e-55,
Organism=Saccharomyces cerevisiae, GI6325292, Length=335, Percent_Identity=47.7611940298507, Blast_Score=279, Evalue=4e-76,
Organism=Drosophila melanogaster, GI281360453, Length=350, Percent_Identity=44.2857142857143, Blast_Score=281, Evalue=5e-76,
Organism=Drosophila melanogaster, GI17136208, Length=350, Percent_Identity=44.2857142857143, Blast_Score=281, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24580558, Length=350, Percent_Identity=44.2857142857143, Blast_Score=281, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24641292, Length=339, Percent_Identity=48.0825958702065, Blast_Score=280, Evalue=9e-76,
Organism=Drosophila melanogaster, GI24641290, Length=339, Percent_Identity=48.0825958702065, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI45554830, Length=268, Percent_Identity=48.8805970149254, Blast_Score=228, Evalue=7e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 41223; Mature: 41092

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAGRGSVRFGFPPFALNRENRMTKYKLEYIWLDGYTPVPNLRGKTQIKEFEIYPTLEQ
CCCCCCCCEEECCCCCEECCCCCCEEEEEEEEEECCCCCCCCCCCCCEEEEEEECCCHHH
LPLWGFDGSSTMQAEGRSSDCVLKPVAMFHDATRKNGILVMCEVMMPDGVTPHATNTRAT
CEEECCCCCCEEECCCCCCCCEEHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEE
ILDDEGAWFGFEQEYFFYKDGRPLGFPEAGYPAPQGPYYTGVGFKNVGNIARKIVEEHLD
EECCCCCEECCCCCEEEEECCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHH
LCLAAGINHEGINAEVAKGQWEFQIFGKGSKTAADQMWMARYLMLRLCESYGIDIEWHCK
HHHHCCCCCCCCCCEEECCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEE
PLGDTDWNGSGMHANFSTKYMREVGGKDYFEALMGQFEKNLHDHIAVYGPDNHMRLTGKH
ECCCCCCCCCCEECCCHHHHHHHCCCHHHHHHHHHHHHHCHHHCEEEECCCCCEEEECCC
ETAPWNKFSYGVADRGASIRVPHSFVNNGYKGYLEDRRPNSMGDPYQIASQILKTISEVP
CCCCCCCEECCCCCCCCEEECCHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCC
TSKAAAA
CCCCCCC
>Mature Secondary Structure 
SAAGRGSVRFGFPPFALNRENRMTKYKLEYIWLDGYTPVPNLRGKTQIKEFEIYPTLEQ
CCCCCCCEEECCCCCEECCCCCCEEEEEEEEEECCCCCCCCCCCCCEEEEEEECCCHHH
LPLWGFDGSSTMQAEGRSSDCVLKPVAMFHDATRKNGILVMCEVMMPDGVTPHATNTRAT
CEEECCCCCCEEECCCCCCCCEEHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEE
ILDDEGAWFGFEQEYFFYKDGRPLGFPEAGYPAPQGPYYTGVGFKNVGNIARKIVEEHLD
EECCCCCEECCCCCEEEEECCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHH
LCLAAGINHEGINAEVAKGQWEFQIFGKGSKTAADQMWMARYLMLRLCESYGIDIEWHCK
HHHHCCCCCCCCCCEEECCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEE
PLGDTDWNGSGMHANFSTKYMREVGGKDYFEALMGQFEKNLHDHIAVYGPDNHMRLTGKH
ECCCCCCCCCCEECCCHHHHHHHCCCHHHHHHHHHHHHHCHHHCEEEECCCCCEEEECCC
ETAPWNKFSYGVADRGASIRVPHSFVNNGYKGYLEDRRPNSMGDPYQIASQILKTISEVP
CCCCCCCEECCCCCCCCEEECCHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCC
TSKAAAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]