Click here to switch to the map view.

The map label for this gene is nuoA

Identifier: 86748472

GI number: 86748472

Start: 1535871

End: 1536260

Strand: Direct

Name: nuoA

Synonym: RPB_1347

Alternate gene names: 86748472

Gene position: 1535871-1536260 (Clockwise)

Preceding gene: 86748467

Following gene: 86748473

Centisome position: 28.81

GC content: 67.44

Gene sequence:

>390_bases
GTGAGTGACTCGATCTTCCCGATCAATCCGGATGCCGCGCTGGCGATCCATGTCGCGCTCTCCGCGGGCATCGTGGCGGC
GATCATCGTCGTTGCCGCCTTGTTGCGCGAGAAGCGCGCCGGCGCGCGCCCCGACGTGCCGTATGAGGGCGGCGTGCTGC
CGGCCGCGCCGCAGCAGGGGCCGATCAACGCACCATATTTCCTGATCGCTGCGCTGTTCGTCATCTTCGACATGGAAGTC
GCGATTCTGTTCGCCTGGGCGGTCGCGGCGCGCGACACCGGCTGGTTCGGGCTGATCGAGGCGGCGGTATTCATCGGCGT
GCTGCTGCTGGCGCTGGTCTATCTGTGGGCCGACGGCGCGCTCGACTGGCACAAGGAGCGCAAGCGATGA

Upstream 100 bases:

>100_bases
GACCTGGATGACATGGTCACCATGACGCACGGGCGGTCCGGATTCCAGACGGGTTCGAATCGCGCGCGTTGCTGTTTGCC
GTTCGCCAGGAGCCTCGTCG

Downstream 100 bases:

>100_bases
CTGACCTGCCGCCCCATGCGCTTCAGCCGGCCGAGCCGGTCTCCGTCGAACAACACATGGCGCTGTCGAGCCTGTTCACC
ACGCTCGAGGACCTGACCGC

Product: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MSDSIFPINPDAALAIHVALSAGIVAAIIVVAALLREKRAGARPDVPYEGGVLPAAPQQGPINAPYFLIAALFVIFDMEV
AILFAWAVAARDTGWFGLIEAAVFIGVLLLALVYLWADGALDWHKERKR

Sequences:

>Translated_129_residues
MSDSIFPINPDAALAIHVALSAGIVAAIIVVAALLREKRAGARPDVPYEGGVLPAAPQQGPINAPYFLIAALFVIFDMEV
AILFAWAVAARDTGWFGLIEAAVFIGVLLLALVYLWADGALDWHKERKR
>Mature_128_residues
SDSIFPINPDAALAIHVALSAGIVAAIIVVAALLREKRAGARPDVPYEGGVLPAAPQQGPINAPYFLIAALFVIFDMEVA
ILFAWAVAARDTGWFGLIEAAVFIGVLLLALVYLWADGALDWHKERKR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=129, Percent_Identity=38.7596899224806, Blast_Score=91, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_RHOP2 (Q2J0F3)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_484968.1
- STRING:   Q2J0F3
- GeneID:   3907855
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_1347
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- OMA:   ALDWHKE
- ProtClustDB:   CLSK589914
- BioCyc:   RPAL316058:RPB_1347-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 13822; Mature: 13691

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b793aac)-; HASH(0x19d59704)-; HASH(0x1c1710e0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSIFPINPDAALAIHVALSAGIVAAIIVVAALLREKRAGARPDVPYEGGVLPAAPQQG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PINAPYFLIAALFVIFDMEVAILFAWAVAARDTGWFGLIEAAVFIGVLLLALVYLWADGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LDWHKERKR
CCHHHHCCH
>Mature Secondary Structure 
SDSIFPINPDAALAIHVALSAGIVAAIIVVAALLREKRAGARPDVPYEGGVLPAAPQQG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PINAPYFLIAALFVIFDMEVAILFAWAVAARDTGWFGLIEAAVFIGVLLLALVYLWADGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LDWHKERKR
CCHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA