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The map label for this gene is mcp4 [H]

Identifier: 86748438

GI number: 86748438

Start: 1495026

End: 1496330

Strand: Direct

Name: mcp4 [H]

Synonym: RPB_1313

Alternate gene names: 86748438

Gene position: 1495026-1496330 (Clockwise)

Preceding gene: 86748437

Following gene: 86748439

Centisome position: 28.04

GC content: 67.36

Gene sequence:

>1305_bases
ATGACGAATTCATCTTCGCTGTCTAAGGCGACGCTCGTTCTGATCGGCGCGATCGTCCTGACGGCCGCGCTCGGCGGCCT
GCGGGTCGCCTACGGCCCGCTCGGGCCGCTGTGGGAAGCGCTCGGCGCCGCGCTCGGCGTCGGCGCGATCGGCATCGCCC
TGTGGCTGACCAGCCGCGCGACGTCCGCGGTCCGCGAGGTCGCATCGGTGTGCGAGAGCGCCAAGCGCGGCGACCTCGAA
GTCCGCGTGATGGGCCGCCGCGACGGCGGCGAAATCGGGCGGGCGCAGGCCGGCATCAACGATGCGCTCGACATCATCGA
CGCGTTCGTCCGCGAAGCCTCGGCGTCGATGGACTATGTCAGCCACGGCAAGACCTTCCGAAAGGTGCTGACCCGCGGTT
TGCCGGGCTCGTTCAAGACCGCGTCGATCACCATCAACAACGCCTCGGACCTGCTGGATAAGAAGGTCCAGGAAGTCGCG
CGCGAAGCGCAATGCTTCGCGGCCGGCATGGACAACGTCGCCGAAATGCTGGCGACCGCCTCCGACGGCCTGAAAGTCGA
TGCCGGCTCGATGTCGACCGCGTCGGAAGAGACCAGCCGGCAGTCGATCGGCGTCGCATCCGGCGCGGAGGAGGCATCCG
CCAACGTGCAGGCGGTGGCCAGCGCGGCGGAGCAACTGACGGCGTCGATCGCCGAGATTTCACGGCAGATTCAGATGTCG
AGTGACAGCACGAACCATGCCGTCGAAGAATCGGCACAGACCACCCTCAAGATCAAGAATTTGGCGGAAGCAGCGCAGCG
GATCGGCGACGTGGTCAAGCTGATCAATGCGGTTGCGGCGCAGACTAATCTGCTGGCGCTGAACGCGACGATCGAGGCCG
CGCGCGCCGGCGAATCCGGCAAGGGTTTCGCCGTCGTCGCCTCCGAAGTGAAGGCGCTCGCCAGCCAGACGGCGAAAGCC
ACCGAGGAGATCACCGCCAGCATCGCCGAGATGCAGGCGATCACAGATCAATCGGTCGAGGCGGTGGATGCCATCAGCCG
GCGGATCGGCGAGATCAACGCGATCGCCGGCACCATCTCCGCCGCGGTGGAGCAGCAGGGCGCCGCCACGCGCGAGATCG
CCGGCAATGTGCAACAGGCGTCGGCCGGCGCCGCGTCGGTCTCGTCGAATGTCATCGGCATCAGCCACGCGGCTTCCGAC
ACCGGCGAGATCGCGGTGCGCGTCAGCAGCGTCTCGGGCGAGATCGCCGGCCAGGTCGACAAGCTGCGCAGCGAGGTGAA
GCGGTTCCTCACCAAGGTCGCGTGA

Upstream 100 bases:

>100_bases
CAATTGCGCGAGGAGGAAAATCGCCACCGCAATGCCAAGGACGGCATGATGAGCGGTTATGCAATGCTGACGGACATGCT
GAAGAAGCAGGGTGTGGGAT

Downstream 100 bases:

>100_bases
TCGCGGAATTCGGCTTCACTCATCCCGGCCGGCTGTCGTCGGCGGGATGTTTGTCCGTAATCTCCCGGAGCCGGGACCTC
CTTGACTTTGGCCGGCAAAC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MTNSSSLSKATLVLIGAIVLTAALGGLRVAYGPLGPLWEALGAALGVGAIGIALWLTSRATSAVREVASVCESAKRGDLE
VRVMGRRDGGEIGRAQAGINDALDIIDAFVREASASMDYVSHGKTFRKVLTRGLPGSFKTASITINNASDLLDKKVQEVA
REAQCFAAGMDNVAEMLATASDGLKVDAGSMSTASEETSRQSIGVASGAEEASANVQAVASAAEQLTASIAEISRQIQMS
SDSTNHAVEESAQTTLKIKNLAEAAQRIGDVVKLINAVAAQTNLLALNATIEAARAGESGKGFAVVASEVKALASQTAKA
TEEITASIAEMQAITDQSVEAVDAISRRIGEINAIAGTISAAVEQQGAATREIAGNVQQASAGAASVSSNVIGISHAASD
TGEIAVRVSSVSGEIAGQVDKLRSEVKRFLTKVA

Sequences:

>Translated_434_residues
MTNSSSLSKATLVLIGAIVLTAALGGLRVAYGPLGPLWEALGAALGVGAIGIALWLTSRATSAVREVASVCESAKRGDLE
VRVMGRRDGGEIGRAQAGINDALDIIDAFVREASASMDYVSHGKTFRKVLTRGLPGSFKTASITINNASDLLDKKVQEVA
REAQCFAAGMDNVAEMLATASDGLKVDAGSMSTASEETSRQSIGVASGAEEASANVQAVASAAEQLTASIAEISRQIQMS
SDSTNHAVEESAQTTLKIKNLAEAAQRIGDVVKLINAVAAQTNLLALNATIEAARAGESGKGFAVVASEVKALASQTAKA
TEEITASIAEMQAITDQSVEAVDAISRRIGEINAIAGTISAAVEQQGAATREIAGNVQQASAGAASVSSNVIGISHAASD
TGEIAVRVSSVSGEIAGQVDKLRSEVKRFLTKVA
>Mature_433_residues
TNSSSLSKATLVLIGAIVLTAALGGLRVAYGPLGPLWEALGAALGVGAIGIALWLTSRATSAVREVASVCESAKRGDLEV
RVMGRRDGGEIGRAQAGINDALDIIDAFVREASASMDYVSHGKTFRKVLTRGLPGSFKTASITINNASDLLDKKVQEVAR
EAQCFAAGMDNVAEMLATASDGLKVDAGSMSTASEETSRQSIGVASGAEEASANVQAVASAAEQLTASIAEISRQIQMSS
DSTNHAVEESAQTTLKIKNLAEAAQRIGDVVKLINAVAAQTNLLALNATIEAARAGESGKGFAVVASEVKALASQTAKAT
EEITASIAEMQAITDQSVEAVDAISRRIGEINAIAGTISAAVEQQGAATREIAGNVQQASAGAASVSSNVIGISHAASDT
GEIAVRVSSVSGEIAGQVDKLRSEVKRFLTKVA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=250, Percent_Identity=29.2, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788194, Length=190, Percent_Identity=33.6842105263158, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788195, Length=184, Percent_Identity=34.7826086956522, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI2367378, Length=229, Percent_Identity=31.8777292576419, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789453, Length=117, Percent_Identity=46.1538461538462, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 44280; Mature: 44149

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSSSLSKATLVLIGAIVLTAALGGLRVAYGPLGPLWEALGAALGVGAIGIALWLTSRA
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TSAVREVASVCESAKRGDLEVRVMGRRDGGEIGRAQAGINDALDIIDAFVREASASMDYV
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHH
SHGKTFRKVLTRGLPGSFKTASITINNASDLLDKKVQEVAREAQCFAAGMDNVAEMLATA
HCCHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDGLKVDAGSMSTASEETSRQSIGVASGAEEASANVQAVASAAEQLTASIAEISRQIQMS
CCCCEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDSTNHAVEESAQTTLKIKNLAEAAQRIGDVVKLINAVAAQTNLLALNATIEAARAGESG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHHHHHCCCCC
KGFAVVASEVKALASQTAKATEEITASIAEMQAITDQSVEAVDAISRRIGEINAIAGTIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVEQQGAATREIAGNVQQASAGAASVSSNVIGISHAASDTGEIAVRVSSVSGEIAGQVD
HHHHHCCCHHHHHHCCHHHHCCCHHHHCCCCEEEECCCCCCCCEEEEEECCCCHHHHHHH
KLRSEVKRFLTKVA
HHHHHHHHHHHHCC
>Mature Secondary Structure 
TNSSSLSKATLVLIGAIVLTAALGGLRVAYGPLGPLWEALGAALGVGAIGIALWLTSRA
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TSAVREVASVCESAKRGDLEVRVMGRRDGGEIGRAQAGINDALDIIDAFVREASASMDYV
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHH
SHGKTFRKVLTRGLPGSFKTASITINNASDLLDKKVQEVAREAQCFAAGMDNVAEMLATA
HCCHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDGLKVDAGSMSTASEETSRQSIGVASGAEEASANVQAVASAAEQLTASIAEISRQIQMS
CCCCEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDSTNHAVEESAQTTLKIKNLAEAAQRIGDVVKLINAVAAQTNLLALNATIEAARAGESG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHHHHHCCCCC
KGFAVVASEVKALASQTAKATEEITASIAEMQAITDQSVEAVDAISRRIGEINAIAGTIS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVEQQGAATREIAGNVQQASAGAASVSSNVIGISHAASDTGEIAVRVSSVSGEIAGQVD
HHHHHCCCHHHHHHCCHHHHCCCHHHHCCCCEEEECCCCCCCCEEEEEECCCCHHHHHHH
KLRSEVKRFLTKVA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]