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The map label for this gene is aer [H]

Identifier: 86748437

GI number: 86748437

Start: 1494527

End: 1495051

Strand: Direct

Name: aer [H]

Synonym: RPB_1312

Alternate gene names: 86748437

Gene position: 1494527-1495051 (Clockwise)

Preceding gene: 86748436

Following gene: 86748438

Centisome position: 28.03

GC content: 59.24

Gene sequence:

>525_bases
ATGGCCAGGCCGCCGATCAAGCCGACAGGCATCGAATGCCCGTTCGACGAGAACGAACTGATCGTCTCGAAAACCAACCT
CAAGGGTCACATCACCTACGCCAACGACGTCTTCATGCGGTTGTCGAAGTACCCACGCAACGAGGTGATCGGCGCGCCGC
ACAGCATGATCCGCCACCCCGACATGCCGCGCACGATCTTCAAGCTGCTGTGGGACACCATCCAGGAGAAGAAGGAGATC
TTCGCCTATGTGGTGAACATGGCGCGCGACGGCGACCACTACTGGGTGTTCGCGCATGTCACGCCGACGCTGGACGCCCA
GAACAACGTCATCGGCTTTCACTCCAACCGCCGCAAGCCGGACCGCGCCCAGCTCGCCAAGATCGAGCCGCTCTACGCGC
AATTGCGCGAGGAGGAAAATCGCCACCGCAATGCCAAGGACGGCATGATGAGCGGTTATGCAATGCTGACGGACATGCTG
AAGAAGCAGGGTGTGGGATATGACGAATTCATCTTCGCTGTCTAA

Upstream 100 bases:

>100_bases
CATCCATTGTTTACCGCCGATGAATTAGGAAGCTCCGATTGTTCGGATTGCGGCGCGACGATCACTTCGTATCGTCCCGT
CCGCCGGGAGGACGCAAGCA

Downstream 100 bases:

>100_bases
GGCGACGCTCGTTCTGATCGGCGCGATCGTCCTGACGGCCGCGCTCGGCGGCCTGCGGGTCGCCTACGGCCCGCTCGGGC
CGCTGTGGGAAGCGCTCGGC

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MARPPIKPTGIECPFDENELIVSKTNLKGHITYANDVFMRLSKYPRNEVIGAPHSMIRHPDMPRTIFKLLWDTIQEKKEI
FAYVVNMARDGDHYWVFAHVTPTLDAQNNVIGFHSNRRKPDRAQLAKIEPLYAQLREEENRHRNAKDGMMSGYAMLTDML
KKQGVGYDEFIFAV

Sequences:

>Translated_174_residues
MARPPIKPTGIECPFDENELIVSKTNLKGHITYANDVFMRLSKYPRNEVIGAPHSMIRHPDMPRTIFKLLWDTIQEKKEI
FAYVVNMARDGDHYWVFAHVTPTLDAQNNVIGFHSNRRKPDRAQLAKIEPLYAQLREEENRHRNAKDGMMSGYAMLTDML
KKQGVGYDEFIFAV
>Mature_173_residues
ARPPIKPTGIECPFDENELIVSKTNLKGHITYANDVFMRLSKYPRNEVIGAPHSMIRHPDMPRTIFKLLWDTIQEKKEIF
AYVVNMARDGDHYWVFAHVTPTLDAQNNVIGFHSNRRKPDRAQLAKIEPLYAQLREEENRHRNAKDGMMSGYAMLTDMLK
KQGVGYDEFIFAV

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=131, Percent_Identity=35.1145038167939, Blast_Score=100, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 20179; Mature: 20047

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPPIKPTGIECPFDENELIVSKTNLKGHITYANDVFMRLSKYPRNEVIGAPHSMIRHP
CCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHCCCCCCCCCCHHHHCCC
DMPRTIFKLLWDTIQEKKEIFAYVVNMARDGDHYWVFAHVTPTLDAQNNVIGFHSNRRKP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCC
DRAQLAKIEPLYAQLREEENRHRNAKDGMMSGYAMLTDMLKKQGVGYDEFIFAV
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEC
>Mature Secondary Structure 
ARPPIKPTGIECPFDENELIVSKTNLKGHITYANDVFMRLSKYPRNEVIGAPHSMIRHP
CCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHCCCCCCCCCCHHHHCCC
DMPRTIFKLLWDTIQEKKEIFAYVVNMARDGDHYWVFAHVTPTLDAQNNVIGFHSNRRKP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCC
DRAQLAKIEPLYAQLREEENRHRNAKDGMMSGYAMLTDMLKKQGVGYDEFIFAV
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]