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The map label for this gene is yliI [H]

Identifier: 86748419

GI number: 86748419

Start: 1476471

End: 1477646

Strand: Reverse

Name: yliI [H]

Synonym: RPB_1294

Alternate gene names: 86748419

Gene position: 1477646-1476471 (Counterclockwise)

Preceding gene: 86748420

Following gene: 86748414

Centisome position: 27.71

GC content: 69.22

Gene sequence:

>1176_bases
ATGAAGACGCTCCTGGTCTGGGTTTCCGGCACGCTGACGGTGGCGACGGTGATCATCGCCTCGTTCCTGATCGCGACCAA
GAGCAGCGGCGAGCCGGCCTCGTTCAAGTCCTCCGCGGGCCCGCTGGCGGTGAAGACCTTCGCACAGAATCTCGACAGCC
CCTGGGCGCTGGCGTTCCTGCCCGAGGGGCGCGTGCTGGTCACCGAGAAGCCGGGGCGGATGCGGGTGGTGTCGGCGCAG
GGTGCGCTGTCGCCGCCGGTCCGGGGCGTTCCCGAGGTCTGGGCCACCGGCCAGGGCGGGCTGCTCGACGTCGTCACCGA
CACGAACTTCGCCGCCAACCGGACGATCTATTTCTGCTACGCTGAACGCACCAGCCAGGGCGGCCGCAGCGGCGGACGCA
CCGCCGTCGCCCGCGCGGCGCTCGTCGAGAGCGACGCGCCACGGCTCGACGACGTGAACGTGATCTTCCGTCAGGACGGC
CCGCTGTCCTCGGGCAATCACTATGGCTGCCGGATCGCGCAAGGCGCCGACGGACACCTGTTCGTCACGCTCGGCGATCA
TTTCAGCTTCCGCGATCAGGCGCAGAATCTCGGCAACCATCTCGGCAAGATCATCCGCATCGCGCCGGACGGCAGCGTGC
CGGCCGGCAATCCGTTCGTCGGGCGCGCCGACGCCAGGCCGGAGATCTGGAGCTACGGCCACCGCAACCCGCAATCGCTC
GCCCTCAATCCGGCGAGCGGCGGGTTGTGGGAGATCGAGCACGGCCCGCGCGGCGGCGACGAGGTCAACATCATTCGGCC
CGGCAACAATTATGGCTGGCCGGTGATCGGCTACGGAATCGACTACAGCGGCGCCACCATCCACGAGGCGGCCGCGAAGT
CCGGTATGGAGCAGCCGGTCAAATATTGGGTGCCGTCGATCGCGCCGTCTGGGATGGCGTTCTACACCGCCAAGCTGTTT
CCGACATGGGCCGGCAGCCTGTTCACCGGCGCGCTCGCCGGCAAGATGCTGGTGCGGCTGTCGCTCGCCGGCGACAAGGT
GACCGGCGAAGAACGCCTGCTGGAGGCGCTGAACGAACGCATCCGCGACGTCCGCCAGGGCCCCGACGGCGCGCTGTGGC
TGCTGACCGACAACGCCGCCGGACGCATCCTGCGCGTGACGCCGGCCGCGGACTGA

Upstream 100 bases:

>100_bases
CGTTTGCGAACTGAACTCCCGTCTCGATCGAACGCTCCGCCTACGCAGCCGCGCTGGCGCTGATGGCATTTTGCTCCGGC
AGAAGCTTGGAGGCCTTGCG

Downstream 100 bases:

>100_bases
GCCGGCGGCCCCGGCGCTAGCGTGCAACGCCGAAGAACAGATTCGGGAAGAACAGCGCGATCTGCGGGAAGATGATCAGG
ATCAGCACGCCCAGCAGCGT

Product: glucose sorbosone dehydrogenase

Products: NA

Alternate protein names: Asd [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKTLLVWVSGTLTVATVIIASFLIATKSSGEPASFKSSAGPLAVKTFAQNLDSPWALAFLPEGRVLVTEKPGRMRVVSAQ
GALSPPVRGVPEVWATGQGGLLDVVTDTNFAANRTIYFCYAERTSQGGRSGGRTAVARAALVESDAPRLDDVNVIFRQDG
PLSSGNHYGCRIAQGADGHLFVTLGDHFSFRDQAQNLGNHLGKIIRIAPDGSVPAGNPFVGRADARPEIWSYGHRNPQSL
ALNPASGGLWEIEHGPRGGDEVNIIRPGNNYGWPVIGYGIDYSGATIHEAAAKSGMEQPVKYWVPSIAPSGMAFYTAKLF
PTWAGSLFTGALAGKMLVRLSLAGDKVTGEERLLEALNERIRDVRQGPDGALWLLTDNAAGRILRVTPAAD

Sequences:

>Translated_391_residues
MKTLLVWVSGTLTVATVIIASFLIATKSSGEPASFKSSAGPLAVKTFAQNLDSPWALAFLPEGRVLVTEKPGRMRVVSAQ
GALSPPVRGVPEVWATGQGGLLDVVTDTNFAANRTIYFCYAERTSQGGRSGGRTAVARAALVESDAPRLDDVNVIFRQDG
PLSSGNHYGCRIAQGADGHLFVTLGDHFSFRDQAQNLGNHLGKIIRIAPDGSVPAGNPFVGRADARPEIWSYGHRNPQSL
ALNPASGGLWEIEHGPRGGDEVNIIRPGNNYGWPVIGYGIDYSGATIHEAAAKSGMEQPVKYWVPSIAPSGMAFYTAKLF
PTWAGSLFTGALAGKMLVRLSLAGDKVTGEERLLEALNERIRDVRQGPDGALWLLTDNAAGRILRVTPAAD
>Mature_391_residues
MKTLLVWVSGTLTVATVIIASFLIATKSSGEPASFKSSAGPLAVKTFAQNLDSPWALAFLPEGRVLVTEKPGRMRVVSAQ
GALSPPVRGVPEVWATGQGGLLDVVTDTNFAANRTIYFCYAERTSQGGRSGGRTAVARAALVESDAPRLDDVNVIFRQDG
PLSSGNHYGCRIAQGADGHLFVTLGDHFSFRDQAQNLGNHLGKIIRIAPDGSVPAGNPFVGRADARPEIWSYGHRNPQSL
ALNPASGGLWEIEHGPRGGDEVNIIRPGNNYGWPVIGYGIDYSGATIHEAAAKSGMEQPVKYWVPSIAPSGMAFYTAKLF
PTWAGSLFTGALAGKMLVRLSLAGDKVTGEERLLEALNERIRDVRQGPDGALWLLTDNAAGRILRVTPAAD

Specific function: Aldose sugar dehydrogenase with broad substrate specificity. The physiological substrate is unknown. Can oxidize glucose to gluconolactone. Can also utilize D-arabinose, L- arabinose and 2-deoxy-glucose. Has higher activity towards oligomeric sugars, such

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PQQ oxidoreductase gdhB family [H]

Homologues:

Organism=Homo sapiens, GI187936953, Length=262, Percent_Identity=28.2442748091603, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI187936955, Length=262, Percent_Identity=28.2442748091603, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI124248546, Length=279, Percent_Identity=25.4480286738351, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1787060, Length=348, Percent_Identity=48.2758620689655, Blast_Score=316, Evalue=2e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 41585; Mature: 41585

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLLVWVSGTLTVATVIIASFLIATKSSGEPASFKSSAGPLAVKTFAQNLDSPWALAFL
CCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEE
PEGRVLVTEKPGRMRVVSAQGALSPPVRGVPEVWATGQGGLLDVVTDTNFAANRTIYFCY
CCCCEEEECCCCCEEEEECCCCCCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCEEEEEE
AERTSQGGRSGGRTAVARAALVESDAPRLDDVNVIFRQDGPLSSGNHYGCRIAQGADGHL
ECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCEE
FVTLGDHFSFRDQAQNLGNHLGKIIRIAPDGSVPAGNPFVGRADARPEIWSYGHRNPQSL
EEEECCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCE
ALNPASGGLWEIEHGPRGGDEVNIIRPGNNYGWPVIGYGIDYSGATIHEAAAKSGMEQPV
EEECCCCCEEEECCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHCCCCCCH
KYWVPSIAPSGMAFYTAKLFPTWAGSLFTGALAGKMLVRLSLAGDKVTGEERLLEALNER
HHHCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHH
IRDVRQGPDGALWLLTDNAAGRILRVTPAAD
HHHHHCCCCCEEEEEECCCCCEEEEEECCCC
>Mature Secondary Structure
MKTLLVWVSGTLTVATVIIASFLIATKSSGEPASFKSSAGPLAVKTFAQNLDSPWALAFL
CCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEE
PEGRVLVTEKPGRMRVVSAQGALSPPVRGVPEVWATGQGGLLDVVTDTNFAANRTIYFCY
CCCCEEEECCCCCEEEEECCCCCCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCEEEEEE
AERTSQGGRSGGRTAVARAALVESDAPRLDDVNVIFRQDGPLSSGNHYGCRIAQGADGHL
ECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCEE
FVTLGDHFSFRDQAQNLGNHLGKIIRIAPDGSVPAGNPFVGRADARPEIWSYGHRNPQSL
EEEECCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCE
ALNPASGGLWEIEHGPRGGDEVNIIRPGNNYGWPVIGYGIDYSGATIHEAAAKSGMEQPV
EEECCCCCEEEECCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHCCCCCCH
KYWVPSIAPSGMAFYTAKLFPTWAGSLFTGALAGKMLVRLSLAGDKVTGEERLLEALNER
HHHCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHH
IRDVRQGPDGALWLLTDNAAGRILRVTPAAD
HHHHHCCCCCEEEEEECCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]