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The map label for this gene is ygjG [C]

Identifier: 86748309

GI number: 86748309

Start: 1357626

End: 1358972

Strand: Reverse

Name: ygjG [C]

Synonym: RPB_1184

Alternate gene names: 86748309

Gene position: 1358972-1357626 (Counterclockwise)

Preceding gene: 86748313

Following gene: 86748308

Centisome position: 25.49

GC content: 67.63

Gene sequence:

>1347_bases
ATGTTAGACAAGAGCAAGCCCAATTCCGCCGTCAACGTCCCGAACGACCTCGATGCGTTCTGGATGCCGTTCACGGCGAA
CCGGGCCTTCAAGCGCGCGCCGAAGATGATCGCGGGCGCCAAGGACATGCACTATTTCACCACGGACGGGCGCAAGATCA
TCGACGCGGCAGCCGGCATGTGGTGCAGCAACGCCGGGCACGGCCGCCCCCAGATTTCCGCGGCGATTGCCGCCCAGGCC
GAGGCGCTGGACTTCTCGCCGCCGTTCCAGTTCGGCCAGCCGAAGGCGTTCGAACTCGCCAGCCGGATCGCGGACCTCGC
CCCCGAAGGCCTCGACCACGTGTTCTTCTGCAATTCCGGCTCGGAAGCCGCCGACACCGCGCTGAAGATCGCGATGGCCT
GGCAGCAGATCCGCGGCCAGGGCGGCCGCACCCGCTTCATCGGCCGCGAGCGCGGCTATCACGGCGTCGGCTTCGGCGGC
ACCGCGGTCGGCGGCATCGGCAACAACCGCAAGATGTTCGGCACGCTCTTGAACGGCGTCGACCATCTGCCCGCGACCTA
TGACCGCGACAAGCAGGCGTTCAGCAAGGGCGAGCCGGAGTACGGCGCGCACTTCGCCGACGCGCTCGAAGGCCTCGTCA
ATCTGCACGGCGCCAACACCATCGCGGCGGTGATCGTCGAGCCGATGGCCGGCTCCACCGGCGTGCTGCCGCCGCCGAAG
GGCTATCTCCAGAAGCTGCGCGAGATCACCAGGAAGCACGGCATCCTGCTGATCTTCGACGAGGTCATCACCGGCTTCGG
CCGTCTCGGCCACAGCTTCGCCGCCGAGCGCTACGGCGTCACCCCGGACATGATCACCTTCGCCAAGGGCGTCACCAACG
GCGCGGTGCCGATGGGCGGCGTGATCGCCAGCTCCGAGATCCACGACGCCTTCATGAGCGGGCCCGATTACGCGATCGAG
CTGTTCCACGGCTACACCTATTCGGCGCATCCCTTGGCCTGCGCGGCCGGCCTCGCCACGCTCGACCTGTATCGCGACGA
GAAGCTGTTCGAGAACGCCAAGGCGCTCGAGCCGGTGTTCGCCGACGCGGTGATGTCGCTGAAGTCCGAGCCGAACGTGG
TCGATATCCGCACCCTCGGCCTGACCGCCGGCATCGACCTGGCGCCGATGGCGGACGGACCCGGCAAGCGCGGCTTCGAG
GCGATGAACTCGGCCTTCCACGACCACGATCTGATGCTGCGGATCGCCGGCGACACCCTGGCCCTGACCCCGCCGCTGAT
CCTCAACGCGGACCAGATCGGCGAAATCGTCGACAAGGTCGGCCGGGTGATCCGCGCCATCGCCTGA

Upstream 100 bases:

>100_bases
CCCACGCAAATGTGCGGGCTCGCGGCATTTCCGGGGCAACCCGAAGCTGCTAGCCTGCCGCGCCGTTCGAAGTCCACGCC
CGCGCATGCACGAGGAGCCT

Downstream 100 bases:

>100_bases
CGCTGCCGCCTGGTTCCCCGGTTGCGGCGGACGAATCCTTTGGACTCGTCCGCCGAATCACCAATGATGGCGGGATCGTC
AGGAACAGCGGCGCTGGATG

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MLDKSKPNSAVNVPNDLDAFWMPFTANRAFKRAPKMIAGAKDMHYFTTDGRKIIDAAAGMWCSNAGHGRPQISAAIAAQA
EALDFSPPFQFGQPKAFELASRIADLAPEGLDHVFFCNSGSEAADTALKIAMAWQQIRGQGGRTRFIGRERGYHGVGFGG
TAVGGIGNNRKMFGTLLNGVDHLPATYDRDKQAFSKGEPEYGAHFADALEGLVNLHGANTIAAVIVEPMAGSTGVLPPPK
GYLQKLREITRKHGILLIFDEVITGFGRLGHSFAAERYGVTPDMITFAKGVTNGAVPMGGVIASSEIHDAFMSGPDYAIE
LFHGYTYSAHPLACAAGLATLDLYRDEKLFENAKALEPVFADAVMSLKSEPNVVDIRTLGLTAGIDLAPMADGPGKRGFE
AMNSAFHDHDLMLRIAGDTLALTPPLILNADQIGEIVDKVGRVIRAIA

Sequences:

>Translated_448_residues
MLDKSKPNSAVNVPNDLDAFWMPFTANRAFKRAPKMIAGAKDMHYFTTDGRKIIDAAAGMWCSNAGHGRPQISAAIAAQA
EALDFSPPFQFGQPKAFELASRIADLAPEGLDHVFFCNSGSEAADTALKIAMAWQQIRGQGGRTRFIGRERGYHGVGFGG
TAVGGIGNNRKMFGTLLNGVDHLPATYDRDKQAFSKGEPEYGAHFADALEGLVNLHGANTIAAVIVEPMAGSTGVLPPPK
GYLQKLREITRKHGILLIFDEVITGFGRLGHSFAAERYGVTPDMITFAKGVTNGAVPMGGVIASSEIHDAFMSGPDYAIE
LFHGYTYSAHPLACAAGLATLDLYRDEKLFENAKALEPVFADAVMSLKSEPNVVDIRTLGLTAGIDLAPMADGPGKRGFE
AMNSAFHDHDLMLRIAGDTLALTPPLILNADQIGEIVDKVGRVIRAIA
>Mature_448_residues
MLDKSKPNSAVNVPNDLDAFWMPFTANRAFKRAPKMIAGAKDMHYFTTDGRKIIDAAAGMWCSNAGHGRPQISAAIAAQA
EALDFSPPFQFGQPKAFELASRIADLAPEGLDHVFFCNSGSEAADTALKIAMAWQQIRGQGGRTRFIGRERGYHGVGFGG
TAVGGIGNNRKMFGTLLNGVDHLPATYDRDKQAFSKGEPEYGAHFADALEGLVNLHGANTIAAVIVEPMAGSTGVLPPPK
GYLQKLREITRKHGILLIFDEVITGFGRLGHSFAAERYGVTPDMITFAKGVTNGAVPMGGVIASSEIHDAFMSGPDYAIE
LFHGYTYSAHPLACAAGLATLDLYRDEKLFENAKALEPVFADAVMSLKSEPNVVDIRTLGLTAGIDLAPMADGPGKRGFE
AMNSAFHDHDLMLRIAGDTLALTPPLILNADQIGEIVDKVGRVIRAIA

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=434, Percent_Identity=28.3410138248848, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI13994255, Length=382, Percent_Identity=30.6282722513089, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI226442705, Length=434, Percent_Identity=28.3410138248848, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI226442709, Length=398, Percent_Identity=29.1457286432161, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI4557809, Length=414, Percent_Identity=25.8454106280193, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI24119277, Length=431, Percent_Identity=25.0580046403712, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI284507298, Length=330, Percent_Identity=26.6666666666667, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI188536080, Length=341, Percent_Identity=23.4604105571848, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI38679950, Length=341, Percent_Identity=23.4604105571848, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI38679946, Length=341, Percent_Identity=23.4604105571848, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI145693181, Length=400, Percent_Identity=30.5, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1786991, Length=435, Percent_Identity=27.3563218390805, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1789759, Length=402, Percent_Identity=28.6069651741293, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788044, Length=426, Percent_Identity=27.4647887323944, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789016, Length=405, Percent_Identity=28.8888888888889, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1787560, Length=345, Percent_Identity=31.5942028985507, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786349, Length=356, Percent_Identity=28.3707865168539, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI32564660, Length=440, Percent_Identity=30, Blast_Score=162, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=434, Percent_Identity=27.1889400921659, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=424, Percent_Identity=25, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25144274, Length=232, Percent_Identity=29.7413793103448, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323470, Length=436, Percent_Identity=27.7522935779816, Blast_Score=162, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6324386, Length=477, Percent_Identity=24.1090146750524, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6324432, Length=412, Percent_Identity=26.2135922330097, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21357415, Length=426, Percent_Identity=24.8826291079812, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI161085790, Length=435, Percent_Identity=26.8965517241379, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28574759, Length=378, Percent_Identity=28.042328042328, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21356575, Length=421, Percent_Identity=27.3159144893112, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 47856; Mature: 47856

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKSKPNSAVNVPNDLDAFWMPFTANRAFKRAPKMIAGAKDMHYFTTDGRKIIDAAAGM
CCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHCHHHHCCCCCCEEEECCCHHHHHHHHCC
WCSNAGHGRPQISAAIAAQAEALDFSPPFQFGQPKAFELASRIADLAPEGLDHVFFCNSG
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCC
SEAADTALKIAMAWQQIRGQGGRTRFIGRERGYHGVGFGGTAVGGIGNNRKMFGTLLNGV
CHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEECCCCCCHHHHHHHHHHH
DHLPATYDRDKQAFSKGEPEYGAHFADALEGLVNLHGANTIAAVIVEPMAGSTGVLPPPK
HCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCH
GYLQKLREITRKHGILLIFDEVITGFGRLGHSFAAERYGVTPDMITFAKGVTNGAVPMGG
HHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCC
VIASSEIHDAFMSGPDYAIELFHGYTYSAHPLACAAGLATLDLYRDEKLFENAKALEPVF
EEECHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAVMSLKSEPNVVDIRTLGLTAGIDLAPMADGPGKRGFEAMNSAFHDHDLMLRIAGDTL
HHHHHHHCCCCCEEEEEEECEECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCEE
ALTPPLILNADQIGEIVDKVGRVIRAIA
EECCCEEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDKSKPNSAVNVPNDLDAFWMPFTANRAFKRAPKMIAGAKDMHYFTTDGRKIIDAAAGM
CCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHCHHHHCCCCCCEEEECCCHHHHHHHHCC
WCSNAGHGRPQISAAIAAQAEALDFSPPFQFGQPKAFELASRIADLAPEGLDHVFFCNSG
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCC
SEAADTALKIAMAWQQIRGQGGRTRFIGRERGYHGVGFGGTAVGGIGNNRKMFGTLLNGV
CHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEECCCCCCHHHHHHHHHHH
DHLPATYDRDKQAFSKGEPEYGAHFADALEGLVNLHGANTIAAVIVEPMAGSTGVLPPPK
HCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCH
GYLQKLREITRKHGILLIFDEVITGFGRLGHSFAAERYGVTPDMITFAKGVTNGAVPMGG
HHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCC
VIASSEIHDAFMSGPDYAIELFHGYTYSAHPLACAAGLATLDLYRDEKLFENAKALEPVF
EEECHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAVMSLKSEPNVVDIRTLGLTAGIDLAPMADGPGKRGFEAMNSAFHDHDLMLRIAGDTL
HHHHHHHCCCCCEEEEEEECEECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCEE
ALTPPLILNADQIGEIVDKVGRVIRAIA
EECCCEEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]