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The map label for this gene is ribBA [H]

Identifier: 86748286

GI number: 86748286

Start: 1330210

End: 1331289

Strand: Direct

Name: ribBA [H]

Synonym: RPB_1161

Alternate gene names: 86748286

Gene position: 1330210-1331289 (Clockwise)

Preceding gene: 86748285

Following gene: 86748287

Centisome position: 24.95

GC content: 66.02

Gene sequence:

>1080_bases
ATGGCGCATCCGATCCAGGACGTTCTGCAAGCCTTCGCTGCCGGCGAAATCGTCGTCGTCACCGACGACGACGATCGCGA
GGGCGAAGGCGACCTCGTGGTCGCGGCCTCGCTGTGCACCGCCGAGAAGATGGCGTTCATCATCCGCCACACCTCCGGCA
TCGTCTGCGCGCCGATCACCATGGACGACGCCCGCCGGTTGCGGCTCGATCCGATGGTCGCGCACAACGACAGCAACCAC
ACCACCGCCTTCACGGTCTCGATCGACTACAAGCCCGACAACGGCACCGGCATCTCCGCCGACGAGCGCGCCTCGTGCTG
CCGGGCGCTCGCCAATCCGAACGCCGGCGCCAATGATTTCGCGCGGCCCGGCCACATCTTCCCGCTGATCGCGCGCGACG
GCGGCGTGCTGCTGCGCTCCGGCCACACCGAGGCCGCGGTCGATCTTTGTCGTTTGGCGGGTCTGCCGCCGGTCGGCGTC
ATCAGCGAATTGATGAACGACGACGGCACTGTCACCAAGGGCGCGCAGGTCGTTGAATTCGCCAGGAAGCACAACCTCAA
ACTGGTCACGATCGCCGACCTGATCGCGCATCGCCAGGCCCGCGAGAAGCTGATCGAGCGCGTCGCGACGTTCCCGCTGG
AAAGCCCGATCGGGCCGATGCAGGGCTACGCCTATCGCTCGCCGTTCGACGAGATCGCGCACGTCGCTTGCGTCTACAAC
GGCATCGGCGACGGCAGGAACGTGCTGACGAGGTTCCACAAGCCGAACATCGTGAAGGAGATCTTCACCGGCGCCCGCCG
GATGGAAGCGGTGCTCGATCACTTCAAGAAGAACGGTTCCGGCGTGCTGATCTATCTGCGCGACGGCGCCGCCGGCGTTC
CGGTCGCGCCGATCGACGAGCCGAAATCGGCGGAAGCCGATCGTCACCGGCAATGGCGCGAGATCGGTGTCGGCGCGCAG
ATCCTGCGCGACCTCGGCGTCTCGTCGATCCGGCATCTCACCTCGTCGCAGCTCGACTACAAGGGCCTGTCCGGTTTCGG
CATCGAGATCGTCGGCAACGAGCACCTTGAAGGCACCTGA

Upstream 100 bases:

>100_bases
TTCCGCTGTGCGGTAGCCGCAACCAGCCCCGCAGCGGCGCGGGTTGCGTCGCCGCGCGCGCTGCGTCATATGGTCGGCTC
TTGTTTCCAGAGAGTGGACC

Downstream 100 bases:

>100_bases
CCAACGTTTTACCTTGCTGCTGTCGCACCATGCGGCAGCGTCCCGAAAGGATGATCGATGAGCGTTCGCGCGCAAACCAA
GGACAAGCCGGCTCCCGCGA

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: 3,4-dihydroxy-2-butanone 4-phosphate synthase; DHBP synthase; GTP cyclohydrolase-2; GTP cyclohydrolase II [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MAHPIQDVLQAFAAGEIVVVTDDDDREGEGDLVVAASLCTAEKMAFIIRHTSGIVCAPITMDDARRLRLDPMVAHNDSNH
TTAFTVSIDYKPDNGTGISADERASCCRALANPNAGANDFARPGHIFPLIARDGGVLLRSGHTEAAVDLCRLAGLPPVGV
ISELMNDDGTVTKGAQVVEFARKHNLKLVTIADLIAHRQAREKLIERVATFPLESPIGPMQGYAYRSPFDEIAHVACVYN
GIGDGRNVLTRFHKPNIVKEIFTGARRMEAVLDHFKKNGSGVLIYLRDGAAGVPVAPIDEPKSAEADRHRQWREIGVGAQ
ILRDLGVSSIRHLTSSQLDYKGLSGFGIEIVGNEHLEGT

Sequences:

>Translated_359_residues
MAHPIQDVLQAFAAGEIVVVTDDDDREGEGDLVVAASLCTAEKMAFIIRHTSGIVCAPITMDDARRLRLDPMVAHNDSNH
TTAFTVSIDYKPDNGTGISADERASCCRALANPNAGANDFARPGHIFPLIARDGGVLLRSGHTEAAVDLCRLAGLPPVGV
ISELMNDDGTVTKGAQVVEFARKHNLKLVTIADLIAHRQAREKLIERVATFPLESPIGPMQGYAYRSPFDEIAHVACVYN
GIGDGRNVLTRFHKPNIVKEIFTGARRMEAVLDHFKKNGSGVLIYLRDGAAGVPVAPIDEPKSAEADRHRQWREIGVGAQ
ILRDLGVSSIRHLTSSQLDYKGLSGFGIEIVGNEHLEGT
>Mature_358_residues
AHPIQDVLQAFAAGEIVVVTDDDDREGEGDLVVAASLCTAEKMAFIIRHTSGIVCAPITMDDARRLRLDPMVAHNDSNHT
TAFTVSIDYKPDNGTGISADERASCCRALANPNAGANDFARPGHIFPLIARDGGVLLRSGHTEAAVDLCRLAGLPPVGVI
SELMNDDGTVTKGAQVVEFARKHNLKLVTIADLIAHRQAREKLIERVATFPLESPIGPMQGYAYRSPFDEIAHVACVYNG
IGDGRNVLTRFHKPNIVKEIFTGARRMEAVLDHFKKNGSGVLIYLRDGAAGVPVAPIDEPKSAEADRHRQWREIGVGAQI
LRDLGVSSIRHLTSSQLDYKGLSGFGIEIVGNEHLEGT

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=199, Percent_Identity=49.748743718593, Blast_Score=193, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320695, Length=203, Percent_Identity=45.8128078817734, Blast_Score=177, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12; =3.5.4.25 [H]

Molecular weight: Translated: 38766; Mature: 38634

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHPIQDVLQAFAAGEIVVVTDDDDREGEGDLVVAASLCTAEKMAFIIRHTSGIVCAPIT
CCCCHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHEEEEECCCEEEEEEE
MDDARRLRLDPMVAHNDSNHTTAFTVSIDYKPDNGTGISADERASCCRALANPNAGANDF
CCCCHHEECCCEEEECCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCC
ARPGHIFPLIARDGGVLLRSGHTEAAVDLCRLAGLPPVGVISELMNDDGTVTKGAQVVEF
CCCCCEEEEEECCCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHH
ARKHNLKLVTIADLIAHRQAREKLIERVATFPLESPIGPMQGYAYRSPFDEIAHVACVYN
HHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
GIGDGRNVLTRFHKPNIVKEIFTGARRMEAVLDHFKKNGSGVLIYLRDGAAGVPVAPIDE
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCC
PKSAEADRHRQWREIGVGAQILRDLGVSSIRHLTSSQLDYKGLSGFGIEIVGNEHLEGT
CCCCCHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
AHPIQDVLQAFAAGEIVVVTDDDDREGEGDLVVAASLCTAEKMAFIIRHTSGIVCAPIT
CCCHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHEEEEECCCEEEEEEE
MDDARRLRLDPMVAHNDSNHTTAFTVSIDYKPDNGTGISADERASCCRALANPNAGANDF
CCCCHHEECCCEEEECCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCC
ARPGHIFPLIARDGGVLLRSGHTEAAVDLCRLAGLPPVGVISELMNDDGTVTKGAQVVEF
CCCCCEEEEEECCCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHH
ARKHNLKLVTIADLIAHRQAREKLIERVATFPLESPIGPMQGYAYRSPFDEIAHVACVYN
HHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
GIGDGRNVLTRFHKPNIVKEIFTGARRMEAVLDHFKKNGSGVLIYLRDGAAGVPVAPIDE
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCC
PKSAEADRHRQWREIGVGAQILRDLGVSSIRHLTSSQLDYKGLSGFGIEIVGNEHLEGT
CCCCCHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA