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The map label for this gene is crp [C]

Identifier: 86748283

GI number: 86748283

Start: 1328703

End: 1329377

Strand: Direct

Name: crp [C]

Synonym: RPB_1158

Alternate gene names: 86748283

Gene position: 1328703-1329377 (Clockwise)

Preceding gene: 86748282

Following gene: 86748284

Centisome position: 24.92

GC content: 70.96

Gene sequence:

>675_bases
ATGAGCTTGCCAGATCTCGGCTGGTTGCAGCGCTTCCCGGCTCTGGCTGGAATGCCCGAGGCCGAGCGCGCGCCGCTGAC
CGGCGGCGCCATGGCGATGAGCCTTCCCGCCGGCACCACGGTGTTCGCGCCGGATCAGCCCTGCAGCATGTTCATCCTCG
TCACCGTCGGCACGGTGCGGGTGTTTCAGCTCGACGCCGAGGGCAACGAGATCGTGCTGTACCGGCTCGGTCCCGGCAGC
ATCTGCATTCTCACCACGCTGGCGCTGCTCGCCTGCGACAGCTACAGCGCCTTCGCCGTCACCGAGACGCCGGTCGAGGC
GGTCGGCCTGCCGGCGGCCACCTTCAACGAGCTGATGGCGCGCTCGGCGCAGTTCCGCAGCTTCGTGTTCAACGCCCAGG
CGGCGCGGATGGCCGACCTGATGGCGGTGATCCAGAACGTCGCCTTCGCCTCGATCGACTCCCGCCTCGCGGCGCGGCTG
CTCGCACTCGCCGACGACAGCCGCGGGCTGTCGATCACGCATCAGCAGCTCGCCGCCGAGATCGGCACCGCGCGCGAAGT
CGTCAGCCGACATCTCAAGACCTTCGAGCGCCGCGGCTGGGTCAGCCTCGGCCGCGGCCGGGTCGAACTGCGCAACGCCG
CGCCGTTGCGCGCCGCGGCCCAGGCCGGCCGCTGA

Upstream 100 bases:

>100_bases
AGCCGCGGCGGTTCGCCGCCGCCGCCCGTTGACAAGGATCAAACGCCCGCCGAATGCTATACGGCATACGAGTAGCAGGG
TGTGGTGAACGGCGGTCGTG

Downstream 100 bases:

>100_bases
GCCGCCCGCCGGTCGCGGGCGGTGACTTCGTCACAGACCGTGTGCCCAGCGTCCCTTACACGTCGAGTGTCACTCAACCA
AGCGAGGGGAATTCAAGATG

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Transcriptional Regulator; CRP Family Transcriptional Regulator; Transcriptional Regulator Crp Family Protein; Transcription Regulator Nnr-Type; Transcriptional Regulator Nnr-Like; Transcriptional Regulator Crp-Fnr Family

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MSLPDLGWLQRFPALAGMPEAERAPLTGGAMAMSLPAGTTVFAPDQPCSMFILVTVGTVRVFQLDAEGNEIVLYRLGPGS
ICILTTLALLACDSYSAFAVTETPVEAVGLPAATFNELMARSAQFRSFVFNAQAARMADLMAVIQNVAFASIDSRLAARL
LALADDSRGLSITHQQLAAEIGTAREVVSRHLKTFERRGWVSLGRGRVELRNAAPLRAAAQAGR

Sequences:

>Translated_224_residues
MSLPDLGWLQRFPALAGMPEAERAPLTGGAMAMSLPAGTTVFAPDQPCSMFILVTVGTVRVFQLDAEGNEIVLYRLGPGS
ICILTTLALLACDSYSAFAVTETPVEAVGLPAATFNELMARSAQFRSFVFNAQAARMADLMAVIQNVAFASIDSRLAARL
LALADDSRGLSITHQQLAAEIGTAREVVSRHLKTFERRGWVSLGRGRVELRNAAPLRAAAQAGR
>Mature_223_residues
SLPDLGWLQRFPALAGMPEAERAPLTGGAMAMSLPAGTTVFAPDQPCSMFILVTVGTVRVFQLDAEGNEIVLYRLGPGSI
CILTTLALLACDSYSAFAVTETPVEAVGLPAATFNELMARSAQFRSFVFNAQAARMADLMAVIQNVAFASIDSRLAARLL
ALADDSRGLSITHQQLAAEIGTAREVVSRHLKTFERRGWVSLGRGRVELRNAAPLRAAAQAGR

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 23892; Mature: 23761

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPDLGWLQRFPALAGMPEAERAPLTGGAMAMSLPAGTTVFAPDQPCSMFILVTVGTVR
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCEEEEEEECEEE
VFQLDAEGNEIVLYRLGPGSICILTTLALLACDSYSAFAVTETPVEAVGLPAATFNELMA
EEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCHHHHHHHHH
RSAQFRSFVFNAQAARMADLMAVIQNVAFASIDSRLAARLLALADDSRGLSITHQQLAAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
IGTAREVVSRHLKTFERRGWVSLGRGRVELRNAAPLRAAAQAGR
HHHHHHHHHHHHHHHHHCCCEEECCCEEEECCCCCHHHHHHCCC
>Mature Secondary Structure 
SLPDLGWLQRFPALAGMPEAERAPLTGGAMAMSLPAGTTVFAPDQPCSMFILVTVGTVR
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCEEEEEEECEEE
VFQLDAEGNEIVLYRLGPGSICILTTLALLACDSYSAFAVTETPVEAVGLPAATFNELMA
EEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCHHHHHHHHH
RSAQFRSFVFNAQAARMADLMAVIQNVAFASIDSRLAARLLALADDSRGLSITHQQLAAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
IGTAREVVSRHLKTFERRGWVSLGRGRVELRNAAPLRAAAQAGR
HHHHHHHHHHHHHHHHHCCCEEECCCEEEECCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA