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The map label for this gene is pcaR [H]

Identifier: 86747880

GI number: 86747880

Start: 845525

End: 846352

Strand: Reverse

Name: pcaR [H]

Synonym: RPB_0754

Alternate gene names: 86747880

Gene position: 846352-845525 (Counterclockwise)

Preceding gene: 86747883

Following gene: 86747879

Centisome position: 15.87

GC content: 71.98

Gene sequence:

>828_bases
ATGCTGGCGGACAGCGCCGGCGATGCCGCGTTCGCCACCACGCTCGCCAAGGGCCTGATCGTGCTCGAAGCGTTCGACGC
CGGCACGCCGCTGCTCGGCAACATGGAGATCGCGGTGCGCACCGGCATCCCGCGGCCGACGGTGGCGCGGCTGACGCATA
CGCTCGCCGAACTCGGCTATCTGCGGTTCGACCCTGCGCTGTCGAAATACGGCGTCGGCCCCCGGGCGCTGCGGATGGCG
CATCCGCTGCTCGCCGACATGCCGTTCCGTCAGCTCGCCCGGCCCCTGATGCAGGATCTGGCGGCGAGCGTGCGCGGCAC
CGTCTCGATCGGCCTGCTCGACGGCCCGTCGGTGATCTATGTCGAAACGGCTCGCTCCGGCGATGTTGGCCCGCACAGCC
CGGACATCGGCATGCCGATCCCGGTGGTGCGCACCGCGATGGGCCGTGCCGCAGCGTCGCTGCTGCCGCCCGACGAGGCC
GAGCTGCTGGCGCGGCGGATCGCTGCGGCCGACCGCTCGGCGTGGGAGCGCGACGGCGAGTTGTATCGCGCCGGCCTGGC
GCAATGCGCGCAGCGCGGCTTCTGCACCTGCTTCGGCGACTACATGCCGTCGATCCACGCCGTGGCGGCGCCGCTGTTCC
GCTCCAGCCGCTTGAAGCGGACGTTTGCGATCAATTGCGGCATCCCGGAATTCCGGCTGCAGCCGGGCCAGCTCGAAGCC
GAGATCGGCCCGCGCATCCGCGCGCTCGCGGCCGCCATCCGCGCGATGTTTCACGAAGCCGACGCCGCGGCCGCGCCACG
GTTGCGGCAGAGCCGGAACGCGAGGTGA

Upstream 100 bases:

>100_bases
TGCTCTAACAGTTGGACAGATTTCCGAAGTTCATCATAATAGGTGGATGATCGAGGACCCGCAGTCGCCTGTCGCGTTCG
CGCCCCTGCCCGCCGGAGCC

Downstream 100 bases:

>100_bases
GATGCGCGCCGCAACGGCGCGGCGAAGCGATCTGAACGGCCATCGACAGGTCCGCCGGCTCAACGAGCGGACCGGAACAA
CGACGGAGGAGACATCATGA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MLADSAGDAAFATTLAKGLIVLEAFDAGTPLLGNMEIAVRTGIPRPTVARLTHTLAELGYLRFDPALSKYGVGPRALRMA
HPLLADMPFRQLARPLMQDLAASVRGTVSIGLLDGPSVIYVETARSGDVGPHSPDIGMPIPVVRTAMGRAAASLLPPDEA
ELLARRIAAADRSAWERDGELYRAGLAQCAQRGFCTCFGDYMPSIHAVAAPLFRSSRLKRTFAINCGIPEFRLQPGQLEA
EIGPRIRALAAAIRAMFHEADAAAAPRLRQSRNAR

Sequences:

>Translated_275_residues
MLADSAGDAAFATTLAKGLIVLEAFDAGTPLLGNMEIAVRTGIPRPTVARLTHTLAELGYLRFDPALSKYGVGPRALRMA
HPLLADMPFRQLARPLMQDLAASVRGTVSIGLLDGPSVIYVETARSGDVGPHSPDIGMPIPVVRTAMGRAAASLLPPDEA
ELLARRIAAADRSAWERDGELYRAGLAQCAQRGFCTCFGDYMPSIHAVAAPLFRSSRLKRTFAINCGIPEFRLQPGQLEA
EIGPRIRALAAAIRAMFHEADAAAAPRLRQSRNAR
>Mature_275_residues
MLADSAGDAAFATTLAKGLIVLEAFDAGTPLLGNMEIAVRTGIPRPTVARLTHTLAELGYLRFDPALSKYGVGPRALRMA
HPLLADMPFRQLARPLMQDLAASVRGTVSIGLLDGPSVIYVETARSGDVGPHSPDIGMPIPVVRTAMGRAAASLLPPDEA
ELLARRIAAADRSAWERDGELYRAGLAQCAQRGFCTCFGDYMPSIHAVAAPLFRSSRLKRTFAINCGIPEFRLQPGQLEA
EIGPRIRALAAAIRAMFHEADAAAAPRLRQSRNAR

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29418; Mature: 29418

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLADSAGDAAFATTLAKGLIVLEAFDAGTPLLGNMEIAVRTGIPRPTVARLTHTLAELGY
CCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCC
LRFDPALSKYGVGPRALRMAHPLLADMPFRQLARPLMQDLAASVRGTVSIGLLDGPSVIY
HHCCCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEE
VETARSGDVGPHSPDIGMPIPVVRTAMGRAAASLLPPDEAELLARRIAAADRSAWERDGE
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LYRAGLAQCAQRGFCTCFGDYMPSIHAVAAPLFRSSRLKRTFAINCGIPEFRLQPGQLEA
HHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCCHHCCCCCCCCH
EIGPRIRALAAAIRAMFHEADAAAAPRLRQSRNAR
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLADSAGDAAFATTLAKGLIVLEAFDAGTPLLGNMEIAVRTGIPRPTVARLTHTLAELGY
CCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCC
LRFDPALSKYGVGPRALRMAHPLLADMPFRQLARPLMQDLAASVRGTVSIGLLDGPSVIY
HHCCCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEE
VETARSGDVGPHSPDIGMPIPVVRTAMGRAAASLLPPDEAELLARRIAAADRSAWERDGE
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LYRAGLAQCAQRGFCTCFGDYMPSIHAVAAPLFRSSRLKRTFAINCGIPEFRLQPGQLEA
HHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCCHHCCCCCCCCH
EIGPRIRALAAAIRAMFHEADAAAAPRLRQSRNAR
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]