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The map label for this gene is hsaA [H]

Identifier: 86747822

GI number: 86747822

Start: 782939

End: 784159

Strand: Direct

Name: hsaA [H]

Synonym: RPB_0696

Alternate gene names: 86747822

Gene position: 782939-784159 (Clockwise)

Preceding gene: 86747821

Following gene: 86747823

Centisome position: 14.68

GC content: 65.52

Gene sequence:

>1221_bases
ATGAACCACATGAATGTGTCCAAGGGCGAATCCTGGAGCGGGTCGCGCGCGTCCGACTTCGACTACAGGGCCGCGGCTCG
CGCGATCCTGCCACGCCTGGCCGCGACGTCGGACAGCAGCGAGCGCCTGCGCAGGCTGGACGACGATGCCGCCGCGGCAC
TCCGCGGATCGGGCCTGGCCCGCGTTCTGACGCCGAAGAAATTCGGCGGCTTCGAGCTCTCCCCAAGCGCCCACATCTGG
ACCTGTGCGGAACTCGCCCAGGGCTGTTCGGCCGCAAGCTGGGTGTTGATGGTTTGTGTGGCCCACGACTACATCGTCGG
ACGGTTCTCGGAAGAGTGCCAGAAGGAAGTCTATGACGGCGACGCCGACAACCTGCTCGCCGGCGCCCTGGCTCCGCAGG
GCACGATCGAACGCACCGCCGGCGGTTGGCGTCTCAATGGGCGTTGGCAATTCGGCAGCGGCTGCGACCATTCTCCCTGG
TTCATTCTCGGCACCAAGGTGGTCAATCCGGACTCGGGCGGCTATCTCAACTACCATGTGATGGTGCCGCGGGCGGACAT
CGAGATCGACGATACGTGGTACACGCTCGGCATGCGCGGAACAGGATCGAAAGATCTCGTCGCACGCGATGTGCTCGTGC
CCGACTATCGGGCGATGCCGACCTATCCGACCTTCATGGGGTCGACCCCGCATACGAACAGTCCCGTCTATCGCTTGCCC
GTCTATGCCGGTCTTTCGTCGATGCTGTCGGGCACCGTGCTCGGGATGGCGGAGCGCGGCTTGAAGCACTTCATCGAGCG
GACCTCCGCCCGCAGGACCGCCCATGGCGTATCGAAGGCGGAGAACGCCAACATGCAACAACGAGTGGCGGAGTCGACGG
CCGAAGTCGCCGCCGCCCGGCGGCTGCTGGAAAACATCTGCGAGCGCTTCGATCAGGCGATGGTTGCCGACCAGGGGCCG
ATGTCCGCCAGCGACCGCGTCCAGTTCCGGTGGGACGCGGCCTATGTCGTCGAACTGAGCCGACGGGCGATCGATCGGGT
GTTCGCCGCTTCCGGCGCACACGGAGTCTACGAGGGCAGCCCGGTGTATCGCGCCTACCGCGATATCAACACGGCCTGCC
ATCACGCGGTGATCGACTTCGACACGGTCTCTGGATTACGCGGGCAGATCGCCCTGCTCGGCGACATCGGCGAGAACCCC
CGTTCGGTGCCTCTCGCCTAG

Upstream 100 bases:

>100_bases
GAGGGCGTGGCGACGGCTGCGCTTGAAGATCGCAAAAGCAGTCGGGCGACACGACGACGGCGACCGAATTTGTCTCGAAA
GATCATAGAGGAGTACTCGA

Downstream 100 bases:

>100_bases
CGGCTTCCAAGCCGCCCTGGTCCGGATGGAGCATGGCACGACGGCGGGGAAACGCGGCCCCGCGCGGACTTGCTCTATCC
GGCCTCTCGCAGATCGGATC

Product: hypothetical protein

Products: NA

Alternate protein names: 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNHMNVSKGESWSGSRASDFDYRAAARAILPRLAATSDSSERLRRLDDDAAAALRGSGLARVLTPKKFGGFELSPSAHIW
TCAELAQGCSAASWVLMVCVAHDYIVGRFSEECQKEVYDGDADNLLAGALAPQGTIERTAGGWRLNGRWQFGSGCDHSPW
FILGTKVVNPDSGGYLNYHVMVPRADIEIDDTWYTLGMRGTGSKDLVARDVLVPDYRAMPTYPTFMGSTPHTNSPVYRLP
VYAGLSSMLSGTVLGMAERGLKHFIERTSARRTAHGVSKAENANMQQRVAESTAEVAAARRLLENICERFDQAMVADQGP
MSASDRVQFRWDAAYVVELSRRAIDRVFAASGAHGVYEGSPVYRAYRDINTACHHAVIDFDTVSGLRGQIALLGDIGENP
RSVPLA

Sequences:

>Translated_406_residues
MNHMNVSKGESWSGSRASDFDYRAAARAILPRLAATSDSSERLRRLDDDAAAALRGSGLARVLTPKKFGGFELSPSAHIW
TCAELAQGCSAASWVLMVCVAHDYIVGRFSEECQKEVYDGDADNLLAGALAPQGTIERTAGGWRLNGRWQFGSGCDHSPW
FILGTKVVNPDSGGYLNYHVMVPRADIEIDDTWYTLGMRGTGSKDLVARDVLVPDYRAMPTYPTFMGSTPHTNSPVYRLP
VYAGLSSMLSGTVLGMAERGLKHFIERTSARRTAHGVSKAENANMQQRVAESTAEVAAARRLLENICERFDQAMVADQGP
MSASDRVQFRWDAAYVVELSRRAIDRVFAASGAHGVYEGSPVYRAYRDINTACHHAVIDFDTVSGLRGQIALLGDIGENP
RSVPLA
>Mature_406_residues
MNHMNVSKGESWSGSRASDFDYRAAARAILPRLAATSDSSERLRRLDDDAAAALRGSGLARVLTPKKFGGFELSPSAHIW
TCAELAQGCSAASWVLMVCVAHDYIVGRFSEECQKEVYDGDADNLLAGALAPQGTIERTAGGWRLNGRWQFGSGCDHSPW
FILGTKVVNPDSGGYLNYHVMVPRADIEIDDTWYTLGMRGTGSKDLVARDVLVPDYRAMPTYPTFMGSTPHTNSPVYRLP
VYAGLSSMLSGTVLGMAERGLKHFIERTSARRTAHGVSKAENANMQQRVAESTAEVAAARRLLENICERFDQAMVADQGP
MSASDRVQFRWDAAYVVELSRRAIDRVFAASGAHGVYEGSPVYRAYRDINTACHHAVIDFDTVSGLRGQIALLGDIGENP
RSVPLA

Specific function: Catalyzes the o-hydroxylation of 3-hydroxy-9,10- seconandrost-1,3,5(10)-triene-9,17-dione (3-HSA) to 3,4-dihydroxy- 9,10-seconandrost-1,3,5(10)-triene-9,17-dione (3,4-DHSA) in the catabolism of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FADH(2)-utilizing monooxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44257; Mature: 44257

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHMNVSKGESWSGSRASDFDYRAAARAILPRLAATSDSSERLRRLDDDAAAALRGSGLA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHCCCCE
RVLTPKKFGGFELSPSAHIWTCAELAQGCSAASWVLMVCVAHDYIVGRFSEECQKEVYDG
EEECCCCCCCEEECCCCCEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DADNLLAGALAPQGTIERTAGGWRLNGRWQFGSGCDHSPWFILGTKVVNPDSGGYLNYHV
CHHHHHHHHCCCCCCCCCCCCCEEECCEEECCCCCCCCCEEEEEEEEECCCCCCEEEEEE
MVPRADIEIDDTWYTLGMRGTGSKDLVARDVLVPDYRAMPTYPTFMGSTPHTNSPVYRLP
EEECCCEEECCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCEEEEH
VYAGLSSMLSGTVLGMAERGLKHFIERTSARRTAHGVSKAENANMQQRVAESTAEVAAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHH
RLLENICERFDQAMVADQGPMSASDRVQFRWDAAYVVELSRRAIDRVFAASGAHGVYEGS
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PVYRAYRDINTACHHAVIDFDTVSGLRGQIALLGDIGENPRSVPLA
HHHHHHHHHHHHHHHHEEEHHHHCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MNHMNVSKGESWSGSRASDFDYRAAARAILPRLAATSDSSERLRRLDDDAAAALRGSGLA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHCCCCE
RVLTPKKFGGFELSPSAHIWTCAELAQGCSAASWVLMVCVAHDYIVGRFSEECQKEVYDG
EEECCCCCCCEEECCCCCEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DADNLLAGALAPQGTIERTAGGWRLNGRWQFGSGCDHSPWFILGTKVVNPDSGGYLNYHV
CHHHHHHHHCCCCCCCCCCCCCEEECCEEECCCCCCCCCEEEEEEEEECCCCCCEEEEEE
MVPRADIEIDDTWYTLGMRGTGSKDLVARDVLVPDYRAMPTYPTFMGSTPHTNSPVYRLP
EEECCCEEECCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCEEEEH
VYAGLSSMLSGTVLGMAERGLKHFIERTSARRTAHGVSKAENANMQQRVAESTAEVAAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHH
RLLENICERFDQAMVADQGPMSASDRVQFRWDAAYVVELSRRAIDRVFAASGAHGVYEGS
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PVYRAYRDINTACHHAVIDFDTVSGLRGQIALLGDIGENPRSVPLA
HHHHHHHHHHHHHHHHEEEHHHHCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA