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The map label for this gene is 86747482

Identifier: 86747482

GI number: 86747482

Start: 398221

End: 399282

Strand: Direct

Name: 86747482

Synonym: RPB_0356

Alternate gene names: NA

Gene position: 398221-399282 (Clockwise)

Preceding gene: 86747481

Following gene: 86747485

Centisome position: 7.47

GC content: 69.59

Gene sequence:

>1062_bases
ATGAACCCGATCTCGCGCCGAACGTTGCTGGCGAGCCTCGCCGCCCTCGCCGCCACGGCCGGGCTTTCCTCGTTCTGGGT
TTCCCGCATGACCTCCTACAAAGGCCCGATCACCGATCATTTCGACGGCGAGCGCTTCTTCGATCGCGACGGCGCGGCGC
CGAAGGGGTGGCTCGACGTGCTGCGCTGGCGCTTCACCACCAAGCCGGCCAAATGGCCGGACTGGGCGCCGAGCCCGTTC
GCCGACACCCCGCCGCCGCGCGTCGAAGGCGCCAGGGCGCGGCTGAGTTTCGTCGGTCATGCGAGCTGGCTGATTCAGAC
CGGCGGGCTCAATATCCTGGTCGATCCGGTGTGGTCGGAGCGGGTGTCGCCGGTCAGCTTCGCCGGCCCCAAGCGGCACA
ACGATCCCGGCATCGCGTTCGACAAGCTGCCCAAGATCGACATCGTGCTGGTGTCGCACGGCCACTACGATCACCTCGAC
CTGGCGACGCTGTCGCGGCTCGCCGCGCAGCATGCACCGCGGGTGATCACGCCGCTCGGCAACGATCTGACGATGGCTTC
GCACGACAGCGCGATCCGCGCCGAGGCCTATGACTGGCGCGACCGCGTCGAGCTCGGGCCCGGCGTCGCCGTGACGCTGG
TGCCGACCCGGCACTGGACCGCGCGCGGCCCGTTCGACCGCAATCGCGCGCTGTGGGCGTCGTTCGTCCTGGAGACGCCG
GCCGGCAGGATCTACGTCGTCTGCGATTCCGGCTATGGCGACGGCCGGCACTTCCGTAACGTCCGCGAGGCGCACGCGCC
GCTGCGGCTGGCGATCCTGCCGATCGGCGCCTATGCGCCGCGCTGGTTCATGAAGGACCAGCACATGAACCCCGCCGACG
CCGTGATGGCGCTGGCGGATTGCGGCGCCCGGCAGGCGCTGGCGAACCATCACGGCACCTTCCAGCTCACCGACGAGGCG
ATCGATGCGCCGGAGCTGGAACTGTATGCGGCGCTCGACGCCGCTGCGGTGCCGCGCGAGCGCTTTCCGGTGCTGAAGCC
GGGGCAGGTTTTCGAAATCTGA

Upstream 100 bases:

>100_bases
CTCGAACTGGCGCAACGCGAGCGAATCGAGCTGGCGACGCTCGACAAGGCGCTGGCGCGCGCGGCGAAGTCCGAAGACGT
CGCGCTGATCGCATGAGCCG

Downstream 100 bases:

>100_bases
CGGAAATTCGATTGCACTGGGCGAGGGATACGCTCTCGTCATTGCGAGGAGCACCCGGATCGGCGCTCCGCGCCGTCCGA
GCACAGGCTCCGCGACGAAG

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MNPISRRTLLASLAALAATAGLSSFWVSRMTSYKGPITDHFDGERFFDRDGAAPKGWLDVLRWRFTTKPAKWPDWAPSPF
ADTPPPRVEGARARLSFVGHASWLIQTGGLNILVDPVWSERVSPVSFAGPKRHNDPGIAFDKLPKIDIVLVSHGHYDHLD
LATLSRLAAQHAPRVITPLGNDLTMASHDSAIRAEAYDWRDRVELGPGVAVTLVPTRHWTARGPFDRNRALWASFVLETP
AGRIYVVCDSGYGDGRHFRNVREAHAPLRLAILPIGAYAPRWFMKDQHMNPADAVMALADCGARQALANHHGTFQLTDEA
IDAPELELYAALDAAAVPRERFPVLKPGQVFEI

Sequences:

>Translated_353_residues
MNPISRRTLLASLAALAATAGLSSFWVSRMTSYKGPITDHFDGERFFDRDGAAPKGWLDVLRWRFTTKPAKWPDWAPSPF
ADTPPPRVEGARARLSFVGHASWLIQTGGLNILVDPVWSERVSPVSFAGPKRHNDPGIAFDKLPKIDIVLVSHGHYDHLD
LATLSRLAAQHAPRVITPLGNDLTMASHDSAIRAEAYDWRDRVELGPGVAVTLVPTRHWTARGPFDRNRALWASFVLETP
AGRIYVVCDSGYGDGRHFRNVREAHAPLRLAILPIGAYAPRWFMKDQHMNPADAVMALADCGARQALANHHGTFQLTDEA
IDAPELELYAALDAAAVPRERFPVLKPGQVFEI
>Mature_353_residues
MNPISRRTLLASLAALAATAGLSSFWVSRMTSYKGPITDHFDGERFFDRDGAAPKGWLDVLRWRFTTKPAKWPDWAPSPF
ADTPPPRVEGARARLSFVGHASWLIQTGGLNILVDPVWSERVSPVSFAGPKRHNDPGIAFDKLPKIDIVLVSHGHYDHLD
LATLSRLAAQHAPRVITPLGNDLTMASHDSAIRAEAYDWRDRVELGPGVAVTLVPTRHWTARGPFDRNRALWASFVLETP
AGRIYVVCDSGYGDGRHFRNVREAHAPLRLAILPIGAYAPRWFMKDQHMNPADAVMALADCGARQALANHHGTFQLTDEA
IDAPELELYAALDAAAVPRERFPVLKPGQVFEI

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=277, Percent_Identity=35.0180505415162, Blast_Score=161, Evalue=7e-40,
Organism=Homo sapiens, GI170932481, Length=277, Percent_Identity=35.0180505415162, Blast_Score=161, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17543100, Length=269, Percent_Identity=33.457249070632, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17543102, Length=269, Percent_Identity=33.457249070632, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI25148824, Length=269, Percent_Identity=33.457249070632, Blast_Score=158, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17543104, Length=268, Percent_Identity=33.2089552238806, Blast_Score=147, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6325154, Length=245, Percent_Identity=31.0204081632653, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 39022; Mature: 39022

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPISRRTLLASLAALAATAGLSSFWVSRMTSYKGPITDHFDGERFFDRDGAAPKGWLDV
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCHHHHHH
LRWRFTTKPAKWPDWAPSPFADTPPPRVEGARARLSFVGHASWLIQTGGLNILVDPVWSE
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEECEEEEEEECCCEEEECCCHHC
RVSPVSFAGPKRHNDPGIAFDKLPKIDIVLVSHGHYDHLDLATLSRLAAQHAPRVITPLG
CCCCCCCCCCCCCCCCCCCHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCC
NDLTMASHDSAIRAEAYDWRDRVELGPGVAVTLVPTRHWTARGPFDRNRALWASFVLETP
CCEEECCCCCHHEHHHCCCHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHEEHHHEECC
AGRIYVVCDSGYGDGRHFRNVREAHAPLRLAILPIGAYAPRWFMKDQHMNPADAVMALAD
CCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHCCCCCCCHHHHHHHHHH
CGARQALANHHGTFQLTDEAIDAPELELYAALDAAAVPRERFPVLKPGQVFEI
CCHHHHHHHCCCEEEECHHHCCCCCEEEEEHHHHHHCCHHHCCCCCCCCEECC
>Mature Secondary Structure
MNPISRRTLLASLAALAATAGLSSFWVSRMTSYKGPITDHFDGERFFDRDGAAPKGWLDV
CCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCHHHHHH
LRWRFTTKPAKWPDWAPSPFADTPPPRVEGARARLSFVGHASWLIQTGGLNILVDPVWSE
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEECEEEEEEECCCEEEECCCHHC
RVSPVSFAGPKRHNDPGIAFDKLPKIDIVLVSHGHYDHLDLATLSRLAAQHAPRVITPLG
CCCCCCCCCCCCCCCCCCCHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCC
NDLTMASHDSAIRAEAYDWRDRVELGPGVAVTLVPTRHWTARGPFDRNRALWASFVLETP
CCEEECCCCCHHEHHHCCCHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHEEHHHEECC
AGRIYVVCDSGYGDGRHFRNVREAHAPLRLAILPIGAYAPRWFMKDQHMNPADAVMALAD
CCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHCCCCCCCHHHHHHHHHH
CGARQALANHHGTFQLTDEAIDAPELELYAALDAAAVPRERFPVLKPGQVFEI
CCHHHHHHHCCCEEEECHHHCCCCCEEEEEHHHHHHCCHHHCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]