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The map label for this gene is asd [H]

Identifier: 86747464

GI number: 86747464

Start: 383425

End: 384459

Strand: Direct

Name: asd [H]

Synonym: RPB_0338

Alternate gene names: 86747464

Gene position: 383425-384459 (Clockwise)

Preceding gene: 86747461

Following gene: 86747465

Centisome position: 7.19

GC content: 63.29

Gene sequence:

>1035_bases
ATGGGTTACAAAGTCGCGGTAGTGGGTGCGACCGGCAATGTCGGGCGCGAAATGCTCGCCATTCTGGACGAGCGCAAGTT
CCCGGCGGACGAGGTGGTGGCGCTGGCGTCGCGCCGCTCGATCGGCGTCGAGGTCAGCTACGGCGACAGGACCCTGAAAT
GCAAGGCGCTGGAGCACTACGATTTCAGCGACATCGACATCTGCCTGATGTCGGCCGGCGGCGCCGTGTCGAAGGAATGG
TCGCCGAAGATCGGCGCGCAGGGCGCGGTGGTGATCGACAATTCCAGCGCCTGGCGGATGGACCCGGACGTGCCGCTGAT
CGTGCCCGAAGTGAACGCCGCGGCCGCCGCGGGCTTCACCAAGAAGAACATCATCGCCAATCCGAACTGCTCGACCGCGC
AGCTCGTGGTGGCGCTGAAGCCGCTGCACGACAAGGCGAAGATCACCCGCGTGGTGGTGTCGACCTATCAGTCGGTGTCG
GGCGCCGGCAAAGAGGGCATGGACGAACTGTTCTCGCAGACCAAGGCCGTCTACACCAATCAGGAACTGATCAATAAGAA
GTTCCCGAAGCGGATCGCCTTCAACGTGATCCCCGAGATCGACGTCTTCATGGAGGACGGCTACACCAAGGAAGAGTGGA
AGATGATGGTCGAGACCAAGAAGATTCTCGATCCCGCCATCAAGCTCTCGGCCACCTGCGTGCGGGTGCCGGTGTTCGTC
GGCCATTCCGAAGCGGTCAATATCGAGTTCGAGAACCCGATCTCCGCCGACGAGGCCCGCGACATCCTGCGCAGCGCGCC
GGGTTGCCTGGTGATCGACAAGCAGGAGCCGGGCGGCTACGTCACGCCGTATGAAGCCGCCGGCGAGGACGCGACCTATA
TCAGCCGCATCCGCACCGACCCGACCGTCGACAACGGCCTGGTGCTGTGGTGCGTCTCGGACAATCTGCGCAAGGGCGCG
GCGCTGAACGCGATCCAGATCGCCGAAGTGCTGATCAACCGCAAGCTGATCACCGCGAAGAAGAAAGCGGCGTAG

Upstream 100 bases:

>100_bases
CAGGTATCAAGTTGTGTCGGCCGCGTTTCTCGCATAGAAGCGCTGACTTCTCCTTGCTGCGGCGCGCCGCGGCGGAGCAA
ATTCCTTCGGAGAGTGAACG

Downstream 100 bases:

>100_bases
TCGCCGGCCGGATCTGCTCCGTCATCCTGAGGTGCCGCCGCGCAGCGGCGGCCTCGAAGGATGGGCCGCACACGCTGCAG
CCGTCGCCGCATCCTTCGAG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGYKVAVVGATGNVGREMLAILDERKFPADEVVALASRRSIGVEVSYGDRTLKCKALEHYDFSDIDICLMSAGGAVSKEW
SPKIGAQGAVVIDNSSAWRMDPDVPLIVPEVNAAAAAGFTKKNIIANPNCSTAQLVVALKPLHDKAKITRVVVSTYQSVS
GAGKEGMDELFSQTKAVYTNQELINKKFPKRIAFNVIPEIDVFMEDGYTKEEWKMMVETKKILDPAIKLSATCVRVPVFV
GHSEAVNIEFENPISADEARDILRSAPGCLVIDKQEPGGYVTPYEAAGEDATYISRIRTDPTVDNGLVLWCVSDNLRKGA
ALNAIQIAEVLINRKLITAKKKAA

Sequences:

>Translated_344_residues
MGYKVAVVGATGNVGREMLAILDERKFPADEVVALASRRSIGVEVSYGDRTLKCKALEHYDFSDIDICLMSAGGAVSKEW
SPKIGAQGAVVIDNSSAWRMDPDVPLIVPEVNAAAAAGFTKKNIIANPNCSTAQLVVALKPLHDKAKITRVVVSTYQSVS
GAGKEGMDELFSQTKAVYTNQELINKKFPKRIAFNVIPEIDVFMEDGYTKEEWKMMVETKKILDPAIKLSATCVRVPVFV
GHSEAVNIEFENPISADEARDILRSAPGCLVIDKQEPGGYVTPYEAAGEDATYISRIRTDPTVDNGLVLWCVSDNLRKGA
ALNAIQIAEVLINRKLITAKKKAA
>Mature_343_residues
GYKVAVVGATGNVGREMLAILDERKFPADEVVALASRRSIGVEVSYGDRTLKCKALEHYDFSDIDICLMSAGGAVSKEWS
PKIGAQGAVVIDNSSAWRMDPDVPLIVPEVNAAAAAGFTKKNIIANPNCSTAQLVVALKPLHDKAKITRVVVSTYQSVSG
AGKEGMDELFSQTKAVYTNQELINKKFPKRIAFNVIPEIDVFMEDGYTKEEWKMMVETKKILDPAIKLSATCVRVPVFVG
HSEAVNIEFENPISADEARDILRSAPGCLVIDKQEPGGYVTPYEAAGEDATYISRIRTDPTVDNGLVLWCVSDNLRKGAA
LNAIQIAEVLINRKLITAKKKAA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=337, Percent_Identity=33.8278931750742, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI1789841, Length=355, Percent_Identity=27.0422535211268, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320362, Length=403, Percent_Identity=31.5136476426799, Blast_Score=100, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37347; Mature: 37216

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYKVAVVGATGNVGREMLAILDERKFPADEVVALASRRSIGVEVSYGDRTLKCKALEHY
CCEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEEECCC
DFSDIDICLMSAGGAVSKEWSPKIGAQGAVVIDNSSAWRMDPDVPLIVPEVNAAAAAGFT
CCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCEEEECCCCHHHCCCC
KKNIIANPNCSTAQLVVALKPLHDKAKITRVVVSTYQSVSGAGKEGMDELFSQTKAVYTN
CCCEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
QELINKKFPKRIAFNVIPEIDVFMEDGYTKEEWKMMVETKKILDPAIKLSATCVRVPVFV
HHHHHHHCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCHHHHHEEEEEEEEEEE
GHSEAVNIEFENPISADEARDILRSAPGCLVIDKQEPGGYVTPYEAAGEDATYISRIRTD
CCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCEECCCCCCCCCHHHHHHHCCC
PTVDNGLVLWCVSDNLRKGAALNAIQIAEVLINRKLITAKKKAA
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCHHEECCCCCC
>Mature Secondary Structure 
GYKVAVVGATGNVGREMLAILDERKFPADEVVALASRRSIGVEVSYGDRTLKCKALEHY
CEEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEEECCC
DFSDIDICLMSAGGAVSKEWSPKIGAQGAVVIDNSSAWRMDPDVPLIVPEVNAAAAAGFT
CCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCEEEECCCCHHHCCCC
KKNIIANPNCSTAQLVVALKPLHDKAKITRVVVSTYQSVSGAGKEGMDELFSQTKAVYTN
CCCEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
QELINKKFPKRIAFNVIPEIDVFMEDGYTKEEWKMMVETKKILDPAIKLSATCVRVPVFV
HHHHHHHCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCHHHHHEEEEEEEEEEE
GHSEAVNIEFENPISADEARDILRSAPGCLVIDKQEPGGYVTPYEAAGEDATYISRIRTD
CCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCEECCCCCCCCCHHHHHHHCCC
PTVDNGLVLWCVSDNLRKGAALNAIQIAEVLINRKLITAKKKAA
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]