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The map label for this gene is qor [H]

Identifier: 86747222

GI number: 86747222

Start: 102027

End: 103001

Strand: Direct

Name: qor [H]

Synonym: RPB_0095

Alternate gene names: 86747222

Gene position: 102027-103001 (Clockwise)

Preceding gene: 86747215

Following gene: 86747224

Centisome position: 1.91

GC content: 66.05

Gene sequence:

>975_bases
ATGAAGGCGATACTCTGCCAGCAATATTGCGGTCCCGACGATCTCGTTCTCACCGAGGTCCCCGATCCGGTCGCCGGCCC
CGGCGAAGCGGTGATCGCGATCAAGGCGGCGGCGCTGAACTTCTTCGACATCCTGATGATTCAGGGCAAGTACCAGATCA
AACCGCCGTTTCCGTTCTCGCCGGGCGCTGAAGTCGCGGGCGTGATCGAGAGCATCGGCGAAGGCGTCACCGATCTGAAA
GTCGGCGACCGCGTGGTGGCGTCCTGCGGCCACAACGGCGCCCGCGAGAAGATCGCGCTTCCGGCCTCGGCGATCATCAA
GATCCCGGACAATCTCGACTACGACCGCGCCGCGGGCATCATCATCATCTACGGCACGGCGCTGCATGCGCTGGACGATC
GCGCCAGCCCGAAGCCGGGCGAAACGCTGGCCGTGCTCGGCGCCGCCGGCGGCACCGGGCTTGCGGCCTGCGAGCTCGGC
AAGCTGATGGGCCTCAAGGTGATCGCCTGCGCCTCGTCGGACGAGAAGCTGGAATTCGCCAAACAGCACGGCGCCGAGCT
GACGCTGAACTACGCCAAGGAAGATCTGAAAGAAGGCCTGAAGAAGCTGACCGGCGGCAAGGGCGTCGACATCATCTTCG
ATCCGGTCGGCGGCACGTACGCCGAAGCCGCCTTGCGCTCGATCGCGTGGGAAGGCCGCTTCCTGGTGATCGGCTTCGCC
GCGGGCGACATCCCGAAAATGCCGCTCAACCTCGCGCTGCTCAAGGGCTGCGACATCCGCGGCGTGTTCTGGGGCGCCTG
GACCAGGATCAACCCGGCCAAGCACCGCGCCAATCTGGAAAAGCTGGTGCAGTGGGCCGCCGAGGGCAAGATCTCCTCGC
ATGTCGACCGCACCTTCCCGCTGGCGCAGACCGCCGACGCCCTCAACGTCCTCGGCGGCCGCCAGGCGATGGGCAAGGTG
ATCCTGCATCCCTGA

Upstream 100 bases:

>100_bases
CGGGGACGTCATTGCGCGCGGCGCGGGCCGAATCCGATTGTCCGTCGCGGCCAAATCCGGCAAGAACGCCCGACAACCAG
AAACCTCCAAGGGTGGATTC

Downstream 100 bases:

>100_bases
GAATGAGAGACTGTGTCCCGGACAAGCGGCAGCGCGTCAGCGCTGCGGCGCAGATCCGGGACCCCGATCTGCCACCGAAA
TAACCGGGGCCCGGATCAGC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKAILCQQYCGPDDLVLTEVPDPVAGPGEAVIAIKAAALNFFDILMIQGKYQIKPPFPFSPGAEVAGVIESIGEGVTDLK
VGDRVVASCGHNGAREKIALPASAIIKIPDNLDYDRAAGIIIIYGTALHALDDRASPKPGETLAVLGAAGGTGLAACELG
KLMGLKVIACASSDEKLEFAKQHGAELTLNYAKEDLKEGLKKLTGGKGVDIIFDPVGGTYAEAALRSIAWEGRFLVIGFA
AGDIPKMPLNLALLKGCDIRGVFWGAWTRINPAKHRANLEKLVQWAAEGKISSHVDRTFPLAQTADALNVLGGRQAMGKV
ILHP

Sequences:

>Translated_324_residues
MKAILCQQYCGPDDLVLTEVPDPVAGPGEAVIAIKAAALNFFDILMIQGKYQIKPPFPFSPGAEVAGVIESIGEGVTDLK
VGDRVVASCGHNGAREKIALPASAIIKIPDNLDYDRAAGIIIIYGTALHALDDRASPKPGETLAVLGAAGGTGLAACELG
KLMGLKVIACASSDEKLEFAKQHGAELTLNYAKEDLKEGLKKLTGGKGVDIIFDPVGGTYAEAALRSIAWEGRFLVIGFA
AGDIPKMPLNLALLKGCDIRGVFWGAWTRINPAKHRANLEKLVQWAAEGKISSHVDRTFPLAQTADALNVLGGRQAMGKV
ILHP
>Mature_324_residues
MKAILCQQYCGPDDLVLTEVPDPVAGPGEAVIAIKAAALNFFDILMIQGKYQIKPPFPFSPGAEVAGVIESIGEGVTDLK
VGDRVVASCGHNGAREKIALPASAIIKIPDNLDYDRAAGIIIIYGTALHALDDRASPKPGETLAVLGAAGGTGLAACELG
KLMGLKVIACASSDEKLEFAKQHGAELTLNYAKEDLKEGLKKLTGGKGVDIIFDPVGGTYAEAALRSIAWEGRFLVIGFA
AGDIPKMPLNLALLKGCDIRGVFWGAWTRINPAKHRANLEKLVQWAAEGKISSHVDRTFPLAQTADALNVLGGRQAMGKV
ILHP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=325, Percent_Identity=32, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI13236495, Length=325, Percent_Identity=32, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI18379349, Length=318, Percent_Identity=28.9308176100629, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=28.6144578313253, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=28.6144578313253, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI194239676, Length=211, Percent_Identity=34.1232227488152, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI24308257, Length=350, Percent_Identity=25.4285714285714, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI41872631, Length=306, Percent_Identity=27.1241830065359, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI28557745, Length=292, Percent_Identity=27.7397260273973, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI197927207, Length=196, Percent_Identity=30.6122448979592, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI67078404, Length=286, Percent_Identity=24.8251748251748, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI67078406, Length=282, Percent_Identity=25.177304964539, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI47519420, Length=338, Percent_Identity=25.7396449704142, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1790485, Length=328, Percent_Identity=30.4878048780488, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790045, Length=278, Percent_Identity=27.6978417266187, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI226510941, Length=327, Percent_Identity=26.9113149847095, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081918, Length=296, Percent_Identity=26.0135135135135, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787863, Length=347, Percent_Identity=25.9365994236311, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789651, Length=230, Percent_Identity=26.5217391304348, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=238, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17536829, Length=286, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI133901710, Length=215, Percent_Identity=30.6976744186047, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI133901712, Length=215, Percent_Identity=30.6976744186047, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319520, Length=328, Percent_Identity=29.5731707317073, Blast_Score=132, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6323729, Length=344, Percent_Identity=22.3837209302326, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24581345, Length=259, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19920632, Length=297, Percent_Identity=22.5589225589226, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI221330659, Length=297, Percent_Identity=22.5589225589226, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34110; Mature: 34110

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAILCQQYCGPDDLVLTEVPDPVAGPGEAVIAIKAAALNFFDILMIQGKYQIKPPFPFS
CCCEEEHHCCCCCCEEEECCCCCCCCCCCEEEEEEEHHHCEEEEEEEECCEEECCCCCCC
PGAEVAGVIESIGEGVTDLKVGDRVVASCGHNGAREKIALPASAIIKIPDNLDYDRAAGI
CCHHHHHHHHHHCCCCCCHHHCHHHHHHCCCCCCCCEEECCCHHEEECCCCCCCCHHCCE
IIIYGTALHALDDRASPKPGETLAVLGAAGGTGLAACELGKLMGLKVIACASSDEKLEFA
EEEECCHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCEEEEEECCCCHHHHHH
KQHGAELTLNYAKEDLKEGLKKLTGGKGVDIIFDPVGGTYAEAALRSIAWEGRFLVIGFA
HHCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEEEE
AGDIPKMPLNLALLKGCDIRGVFWGAWTRINPAKHRANLEKLVQWAAEGKISSHVDRTFP
CCCCCCCCCEEEEECCCCCCEEEEECCEECCHHHHHHHHHHHHHHHHCCCHHHHHHCCCC
LAQTADALNVLGGRQAMGKVILHP
CHHHHHHHHHHCCHHHHCCEECCC
>Mature Secondary Structure
MKAILCQQYCGPDDLVLTEVPDPVAGPGEAVIAIKAAALNFFDILMIQGKYQIKPPFPFS
CCCEEEHHCCCCCCEEEECCCCCCCCCCCEEEEEEEHHHCEEEEEEEECCEEECCCCCCC
PGAEVAGVIESIGEGVTDLKVGDRVVASCGHNGAREKIALPASAIIKIPDNLDYDRAAGI
CCHHHHHHHHHHCCCCCCHHHCHHHHHHCCCCCCCCEEECCCHHEEECCCCCCCCHHCCE
IIIYGTALHALDDRASPKPGETLAVLGAAGGTGLAACELGKLMGLKVIACASSDEKLEFA
EEEECCHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCEEEEEECCCCHHHHHH
KQHGAELTLNYAKEDLKEGLKKLTGGKGVDIIFDPVGGTYAEAALRSIAWEGRFLVIGFA
HHCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEEEE
AGDIPKMPLNLALLKGCDIRGVFWGAWTRINPAKHRANLEKLVQWAAEGKISSHVDRTFP
CCCCCCCCCEEEEECCCCCCEEEEECCEECCHHHHHHHHHHHHHHHHCCCHHHHHHCCCC
LAQTADALNVLGGRQAMGKVILHP
CHHHHHHHHHHCCHHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]