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The map label for this gene is tas [H]

Identifier: 86610348

GI number: 86610348

Start: 3028128

End: 3029168

Strand: Direct

Name: tas [H]

Synonym: CYB_2928

Alternate gene names: 86610348

Gene position: 3028128-3029168 (Clockwise)

Preceding gene: 86610347

Following gene: 86610349

Centisome position: 99.39

GC content: 61.67

Gene sequence:

>1041_bases
ATGCGCTACCGCCAGCTTGGCCACAGCCCTTTGCAAGTTTCCGAGATCTGCCTGGGCACCATGACCTTTGGGCAGCAGAA
TACTTTGTCTGAGGCTTTCGAACAGCTCGACTACGCGGTGGAGCACGGGATCAACTTCATCGATACCGCCGAGATGTACC
CGGTGCCGGCGCGGGCGGAAACCCAGGGATCCACCGAGCGCTACATCGGCGAGTGGCTACAACACCAACCGCGGCATCGC
CTGATCCTGGCCACCAAGATCACCGGCCCTGGTCGGCCCTGGCATTGGATTCGCGGCGGATCCCTGTCCATCACCCGCGA
CAACCTCAAGCAGGCGGTGGCCGATAGCCTCAAACGCCTGAAGACCGACTACATCGACCTCTACCAGATCCACTGGCCGG
ATCGCTACGTGCCCCTGTTTGGGGGCGTTGCCTACGATCCCAGCCAGGAGCGGCCCACCGTTCCCATTGCCGAGCAGTTG
CAGGCTCTGGCGGAATTGGTGCAAGAGGGTCTCATTCGCTACATCGGCCTGAGCAACGAAACCCCTTGGGGGGTGAGCAA
GTTCTGCCAGGTGGCCGAGCAACTGGGGTTGCCCAAGGTGGTCTCGATTCAGAATGCCTACAGCCTCATCAACCGCACGT
TTGAAATGGGCCTGGCGGAAGTCTGCCGCCACGAGCAGGTGGGCTTGCTGGCCTACAGCCCGCTCGGATTTGGGCTGCTG
ACGGGCAAATATCTGGGGGGGGTGAAGCCGCCGGGATCCCGTTTGGCCTTGTTTGAAGGCTTTGGCCAGCGGTACCGCAA
GCCCAATGTGGAAGAAGCGGTGGCTGCCTATGTGCAAATTGCCCGCCGGCACGGTCTGACACCGGCCCAGTTGGCTTTGG
CCTTTGTGCGCAGCCGCTGGTTTGTCACCAGCACCATCATTGGGGCCACCAGCCTGACCCAACTCAAAGAGAACCTCAGT
TGCCTGGATGTGGAGCTGTCCCCGCAGATCCTGGCGGAGATCGAAGCGGTTCACCAGCGCTACCCCAATCCTGCCCCCTG
A

Upstream 100 bases:

>100_bases
GAAATAGGAACGGGGGCATAGCGGGGGATCCCGTAGGCCGACAGGTTTTGGGCACAATGGGGACTGGCGCGCTGTCTAGG
GTTGGAGACGGAGATTCCCC

Downstream 100 bases:

>100_bases
AAGGTTGGCGAAACCGGTGGCCAGACAGAACTTTTCAGAAGGTTTCCTCGTCTGGGTGTGCGGTTTGGATCATCCTCTCC
TACACTTCTGTCCGGCCAAC

Product: aldo/keto reductase Tas

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MRYRQLGHSPLQVSEICLGTMTFGQQNTLSEAFEQLDYAVEHGINFIDTAEMYPVPARAETQGSTERYIGEWLQHQPRHR
LILATKITGPGRPWHWIRGGSLSITRDNLKQAVADSLKRLKTDYIDLYQIHWPDRYVPLFGGVAYDPSQERPTVPIAEQL
QALAELVQEGLIRYIGLSNETPWGVSKFCQVAEQLGLPKVVSIQNAYSLINRTFEMGLAEVCRHEQVGLLAYSPLGFGLL
TGKYLGGVKPPGSRLALFEGFGQRYRKPNVEEAVAAYVQIARRHGLTPAQLALAFVRSRWFVTSTIIGATSLTQLKENLS
CLDVELSPQILAEIEAVHQRYPNPAP

Sequences:

>Translated_346_residues
MRYRQLGHSPLQVSEICLGTMTFGQQNTLSEAFEQLDYAVEHGINFIDTAEMYPVPARAETQGSTERYIGEWLQHQPRHR
LILATKITGPGRPWHWIRGGSLSITRDNLKQAVADSLKRLKTDYIDLYQIHWPDRYVPLFGGVAYDPSQERPTVPIAEQL
QALAELVQEGLIRYIGLSNETPWGVSKFCQVAEQLGLPKVVSIQNAYSLINRTFEMGLAEVCRHEQVGLLAYSPLGFGLL
TGKYLGGVKPPGSRLALFEGFGQRYRKPNVEEAVAAYVQIARRHGLTPAQLALAFVRSRWFVTSTIIGATSLTQLKENLS
CLDVELSPQILAEIEAVHQRYPNPAP
>Mature_346_residues
MRYRQLGHSPLQVSEICLGTMTFGQQNTLSEAFEQLDYAVEHGINFIDTAEMYPVPARAETQGSTERYIGEWLQHQPRHR
LILATKITGPGRPWHWIRGGSLSITRDNLKQAVADSLKRLKTDYIDLYQIHWPDRYVPLFGGVAYDPSQERPTVPIAEQL
QALAELVQEGLIRYIGLSNETPWGVSKFCQVAEQLGLPKVVSIQNAYSLINRTFEMGLAEVCRHEQVGLLAYSPLGFGLL
TGKYLGGVKPPGSRLALFEGFGQRYRKPNVEEAVAAYVQIARRHGLTPAQLALAFVRSRWFVTSTIIGATSLTQLKENLS
CLDVELSPQILAEIEAVHQRYPNPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=354, Percent_Identity=30.5084745762712, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI4504825, Length=352, Percent_Identity=30.3977272727273, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI27436971, Length=358, Percent_Identity=31.0055865921788, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI27436964, Length=355, Percent_Identity=28.7323943661972, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI27436962, Length=355, Percent_Identity=28.7323943661972, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI27436966, Length=355, Percent_Identity=28.4507042253521, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI41327764, Length=350, Percent_Identity=27.7142857142857, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI41152114, Length=257, Percent_Identity=29.5719844357977, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI223718702, Length=344, Percent_Identity=27.906976744186, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=55.6195965417867, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI87081735, Length=356, Percent_Identity=31.4606741573034, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788070, Length=344, Percent_Identity=30.2325581395349, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789375, Length=346, Percent_Identity=30.9248554913295, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788081, Length=309, Percent_Identity=28.8025889967638, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787674, Length=335, Percent_Identity=25.3731343283582, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786400, Length=320, Percent_Identity=26.875, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI212645785, Length=344, Percent_Identity=24.7093023255814, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319958, Length=314, Percent_Identity=28.6624203821656, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6323998, Length=338, Percent_Identity=28.9940828402367, Blast_Score=116, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6319951, Length=343, Percent_Identity=26.8221574344023, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6322615, Length=266, Percent_Identity=26.3157894736842, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6325169, Length=353, Percent_Identity=24.0793201133144, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321052, Length=146, Percent_Identity=34.9315068493151, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646159, Length=235, Percent_Identity=29.7872340425532, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646155, Length=335, Percent_Identity=26.5671641791045, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38755; Mature: 38755

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYRQLGHSPLQVSEICLGTMTFGQQNTLSEAFEQLDYAVEHGINFIDTAEMYPVPARAE
CCCHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC
TQGSTERYIGEWLQHQPRHRLILATKITGPGRPWHWIRGGSLSITRDNLKQAVADSLKRL
CCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEECCCEEEEHHHHHHHHHHHHHHH
KTDYIDLYQIHWPDRYVPLFGGVAYDPSQERPTVPIAEQLQALAELVQEGLIRYIGLSNE
HHHHHEEEEEECCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
TPWGVSKFCQVAEQLGLPKVVSIQNAYSLINRTFEMGLAEVCRHEQVGLLAYSPLGFGLL
CCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHH
TGKYLGGVKPPGSRLALFEGFGQRYRKPNVEEAVAAYVQIARRHGLTPAQLALAFVRSRW
HHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FVTSTIIGATSLTQLKENLSCLDVELSPQILAEIEAVHQRYPNPAP
HHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRYRQLGHSPLQVSEICLGTMTFGQQNTLSEAFEQLDYAVEHGINFIDTAEMYPVPARAE
CCCHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC
TQGSTERYIGEWLQHQPRHRLILATKITGPGRPWHWIRGGSLSITRDNLKQAVADSLKRL
CCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEECCCEEEEHHHHHHHHHHHHHHH
KTDYIDLYQIHWPDRYVPLFGGVAYDPSQERPTVPIAEQLQALAELVQEGLIRYIGLSNE
HHHHHEEEEEECCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
TPWGVSKFCQVAEQLGLPKVVSIQNAYSLINRTFEMGLAEVCRHEQVGLLAYSPLGFGLL
CCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHH
TGKYLGGVKPPGSRLALFEGFGQRYRKPNVEEAVAAYVQIARRHGLTPAQLALAFVRSRW
HHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FVTSTIIGATSLTQLKENLSCLDVELSPQILAEIEAVHQRYPNPAP
HHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]