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The map label for this gene is 86609922

Identifier: 86609922

GI number: 86609922

Start: 2583792

End: 2584970

Strand: Direct

Name: 86609922

Synonym: CYB_2488

Alternate gene names: NA

Gene position: 2583792-2584970 (Clockwise)

Preceding gene: 86609921

Following gene: 86609923

Centisome position: 84.81

GC content: 63.53

Gene sequence:

>1179_bases
ATGCCGTTTGTGATTGCCCCGACCGACGTGGGCGTGCTGGTGCTGGGGGCGAGCCTGTTGCTTTTGGCCGGGGGTTGGGC
CTGGTGGCTGCGGCGGCAGAAGCGTGCTGCCTCCCCAGAATCTACAGCCGTTTCGCCGGCCCCGGCGGTTGACCCATCTG
CCCTTTCGGCGGAACAGGCGGCTCAACTACAGCCCTTCGAGCAGGCGGTGGGAGATCAGCCGCAGGATCCCATTGCCTGG
TACAACCGCGCCACCACCCTCGACCACCTGGGGCAAGCCCAAGCTGCCCTGGCCAGCTACGACCGCGCCCTGGAGCTGAA
GCCGGACTTCCCCGAAGCCTGGAACAACCGTGGTTCTCTGCTGGACGATCTCGGTCGCCATCAAGAAGCTCTGGCCAGCT
ATGAGCGGGCTCTGCGGCTGAAACCGGATTTTTTTGAGGCCCGCTTTAACCAGGCCAACACGCTGCGGCAATTGGGCCGC
TACGAAGAAGCCCTACGTGCCTACGAACGGGCCCTTGCCCTCAGCCCCGACAGCCCGGAAACGTGGTACCTGCACGGGCT
AACCTTAGCCTCTCTGGGACGGTGGCAGGGATCCCTAATCAGCTACGAGAAAGCCCTCGCCATCAACCCCGTCAATGCCC
AAGTTTGGCAGAGTCGGGGCCTGGCTCTGTTTCACCTAGAGCGCTACGTCGATGCTCTGGCCAGCTACGAACGAGCCCTG
CAACTGGGCTCCGAATCGGCCTCTCTCTGGGCCGGCCATGCCCTTGCCCACCACCGCCTCGGCAACCCGATGGAGGCCCT
CAACAGCTATGACCGTGCCCTGGCGCAGGATCCCAAACGCCCTCAGATCTGGGTGCAGCGCGGCCTGGTGCTGATGGACT
TGAACCTCTACGAGCTGGCCATCCAGAGTTTTGATCGGGCCCTGCAGATGGATCCCAGCAATGCCGAGGCTCACTACGCC
AAAGCCTGCTGCTACGCCTGGGAAGGCCAAGTGCCTCAGGCCCTACAAGCTTTGGAGCAAGCCCTACGCCTGGAGCCGGA
ACGCTACCGCCCCTTGCTCTCCTCTGAGCCCTATTTCGACCTCATTCGCGAGGAGCCGAGTTTTGCATCCTTTTTGGCAG
CCCTTGCCGGCACGGATCCCCCCAAGAACCCCCCGCCGCTGTCACGAACAGCCTCTTGA

Upstream 100 bases:

>100_bases
TGGCGAAAAGCGCATTGAGCTGATCTCGCCGGCAGGGCCCAGCGATCCCCTGCCGTTTTTGGTGATGATGTAGAGGCGCG
CAGAAAAGAGGAAGTGGGTC

Downstream 100 bases:

>100_bases
CGTTCTCACCTCCCAGAAGGAGAGGAGAGGCTGGAATGCACAGGCTGTTTCACCGCCAACCTGACCCAATCACCAATAAC
CACGAGAGCACGCCAACAAC

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MPFVIAPTDVGVLVLGASLLLLAGGWAWWLRRQKRAASPESTAVSPAPAVDPSALSAEQAAQLQPFEQAVGDQPQDPIAW
YNRATTLDHLGQAQAALASYDRALELKPDFPEAWNNRGSLLDDLGRHQEALASYERALRLKPDFFEARFNQANTLRQLGR
YEEALRAYERALALSPDSPETWYLHGLTLASLGRWQGSLISYEKALAINPVNAQVWQSRGLALFHLERYVDALASYERAL
QLGSESASLWAGHALAHHRLGNPMEALNSYDRALAQDPKRPQIWVQRGLVLMDLNLYELAIQSFDRALQMDPSNAEAHYA
KACCYAWEGQVPQALQALEQALRLEPERYRPLLSSEPYFDLIREEPSFASFLAALAGTDPPKNPPPLSRTAS

Sequences:

>Translated_392_residues
MPFVIAPTDVGVLVLGASLLLLAGGWAWWLRRQKRAASPESTAVSPAPAVDPSALSAEQAAQLQPFEQAVGDQPQDPIAW
YNRATTLDHLGQAQAALASYDRALELKPDFPEAWNNRGSLLDDLGRHQEALASYERALRLKPDFFEARFNQANTLRQLGR
YEEALRAYERALALSPDSPETWYLHGLTLASLGRWQGSLISYEKALAINPVNAQVWQSRGLALFHLERYVDALASYERAL
QLGSESASLWAGHALAHHRLGNPMEALNSYDRALAQDPKRPQIWVQRGLVLMDLNLYELAIQSFDRALQMDPSNAEAHYA
KACCYAWEGQVPQALQALEQALRLEPERYRPLLSSEPYFDLIREEPSFASFLAALAGTDPPKNPPPLSRTAS
>Mature_391_residues
PFVIAPTDVGVLVLGASLLLLAGGWAWWLRRQKRAASPESTAVSPAPAVDPSALSAEQAAQLQPFEQAVGDQPQDPIAWY
NRATTLDHLGQAQAALASYDRALELKPDFPEAWNNRGSLLDDLGRHQEALASYERALRLKPDFFEARFNQANTLRQLGRY
EEALRAYERALALSPDSPETWYLHGLTLASLGRWQGSLISYEKALAINPVNAQVWQSRGLALFHLERYVDALASYERALQ
LGSESASLWAGHALAHHRLGNPMEALNSYDRALAQDPKRPQIWVQRGLVLMDLNLYELAIQSFDRALQMDPSNAEAHYAK
ACCYAWEGQVPQALQALEQALRLEPERYRPLLSSEPYFDLIREEPSFASFLAALAGTDPPKNPPPLSRTAS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=286, Percent_Identity=26.5734265734266, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI32307148, Length=286, Percent_Identity=26.5734265734266, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI170784867, Length=294, Percent_Identity=25.5102040816327, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI224809432, Length=210, Percent_Identity=27.6190476190476, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI83415184, Length=269, Percent_Identity=27.1375464684015, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI301336134, Length=269, Percent_Identity=27.1375464684015, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI167466177, Length=341, Percent_Identity=21.1143695014663, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI167466175, Length=341, Percent_Identity=21.1143695014663, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI296531396, Length=175, Percent_Identity=25.7142857142857, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI118766330, Length=291, Percent_Identity=25.085910652921, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI118766328, Length=291, Percent_Identity=25.085910652921, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI310131789, Length=209, Percent_Identity=23.444976076555, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI310110582, Length=209, Percent_Identity=23.444976076555, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI310123097, Length=209, Percent_Identity=23.444976076555, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI262206280, Length=319, Percent_Identity=23.8244514106583, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI42476022, Length=233, Percent_Identity=25.3218884120172, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI301898023, Length=233, Percent_Identity=25.3218884120172, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI221219056, Length=311, Percent_Identity=24.1157556270096, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=299, Percent_Identity=25.752508361204, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI115532692, Length=269, Percent_Identity=26.7657992565056, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25147174, Length=264, Percent_Identity=23.8636363636364, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319387, Length=244, Percent_Identity=24.5901639344262, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319589, Length=289, Percent_Identity=26.643598615917, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17647755, Length=221, Percent_Identity=31.2217194570136, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24585827, Length=221, Percent_Identity=31.2217194570136, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24585829, Length=221, Percent_Identity=31.2217194570136, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24647123, Length=218, Percent_Identity=28.4403669724771, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24656717, Length=296, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18110006, Length=296, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137540, Length=231, Percent_Identity=23.8095238095238, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 43576; Mature: 43445

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFVIAPTDVGVLVLGASLLLLAGGWAWWLRRQKRAASPESTAVSPAPAVDPSALSAEQA
CCEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCHHHH
AQLQPFEQAVGDQPQDPIAWYNRATTLDHLGQAQAALASYDRALELKPDFPEAWNNRGSL
HHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCHHHCCCCCH
LDDLGRHQEALASYERALRLKPDFFEARFNQANTLRQLGRYEEALRAYERALALSPDSPE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TWYLHGLTLASLGRWQGSLISYEKALAINPVNAQVWQSRGLALFHLERYVDALASYERAL
EEEEECHHHHHHHHHCCHHHHHHHHHEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QLGSESASLWAGHALAHHRLGNPMEALNSYDRALAQDPKRPQIWVQRGLVLMDLNLYELA
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHCCEEEEECHHHHHH
IQSFDRALQMDPSNAEAHYAKACCYAWEGQVPQALQALEQALRLEPERYRPLLSSEPYFD
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHCCCCCCCCHHH
LIREEPSFASFLAALAGTDPPKNPPPLSRTAS
HHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PFVIAPTDVGVLVLGASLLLLAGGWAWWLRRQKRAASPESTAVSPAPAVDPSALSAEQA
CEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCHHHH
AQLQPFEQAVGDQPQDPIAWYNRATTLDHLGQAQAALASYDRALELKPDFPEAWNNRGSL
HHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCHHHCCCCCH
LDDLGRHQEALASYERALRLKPDFFEARFNQANTLRQLGRYEEALRAYERALALSPDSPE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TWYLHGLTLASLGRWQGSLISYEKALAINPVNAQVWQSRGLALFHLERYVDALASYERAL
EEEEECHHHHHHHHHCCHHHHHHHHHEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QLGSESASLWAGHALAHHRLGNPMEALNSYDRALAQDPKRPQIWVQRGLVLMDLNLYELA
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHCCEEEEECHHHHHH
IQSFDRALQMDPSNAEAHYAKACCYAWEGQVPQALQALEQALRLEPERYRPLLSSEPYFD
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHCCCCCCCCHHH
LIREEPSFASFLAALAGTDPPKNPPPLSRTAS
HHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]