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The map label for this gene is rpoC1 [H]

Identifier: 86609872

GI number: 86609872

Start: 2535851

End: 2537734

Strand: Direct

Name: rpoC1 [H]

Synonym: CYB_2437

Alternate gene names: 86609872

Gene position: 2535851-2537734 (Clockwise)

Preceding gene: 86609871

Following gene: 86609873

Centisome position: 83.23

GC content: 59.77

Gene sequence:

>1884_bases
ATGGCCAAAACAGAGCAACGCTTTGACTATGTCAAAATCGGCTTGGCTTCTCCAGAACGGATCATGGAGTGGGGCCAGCG
CACCCTGCCGAATGGTCAAGTGGTGGGGGAAGTCACCAAGCCCGAGACCATCAATTACCGCACCCTCAAGCCGGAGATGG
ATGGTCTTTTCTGTGAGCGCATCTTTGGGCCGGCCAAAGACTGGGAATGCCACTGCGGTAAGTACAAGCGAGTACGGCAT
CGGGGGATCGTCTGCGAGCGCTGTGGGGTGGAGGTGACCGAGTCGCGGGTGCGCCGCCACCGCATGGGCTACATCAAGTT
GGCCGCTCCGGTCACCCACGTTTGGTATTTGAAAGGGATCCCCAGCCACATCGCCACCCTGTTGGACATGCCGCTGCGGG
ATGTGGAGCAAGTGGTGTACTTCAACGCCTACGTAGTGGTGGATCCGGGCAATGCCCAGAATCTCTCCTACAAACAACTG
TTGACGGAGGATCAATTCCTCGAGATCGAAGATCAGATGTACGAGGAGGGATCCGAACTGCAACTGCCGGAGAACTGGGC
GATGATCGGGGCGGAGGCCATCGAGCGCCTGCTCAAGGATATCGACCTGGAAAAAGAGGCGGAGCAACTGCGGGAGGAGA
TCACCAGTGCTCGCGGCCAAAAGCGGGCGCGCCTGATCAAGCGGCTGCGGGTAATCGACAACTTCATCGCCACCGGATCC
CGTCCGGAGTGGATGGTGTTGCGGGTGCTGCCGGTGATCCCGCCGGATCTGCGCCCCATGGTGCAGTTGGATGGGGGCCG
CTTTGCCACCAGCGACCTCAACGATCTCTACCGTCGTGTGATCAACCGCAACAACCGCCTGGCCCGGCTGCAGGAGATCA
TGGCGCCGGAGATCATTGTGCGCAACGAAAAGCGCATGCTCCAGGAGGCGGTGGACGCGCTGATCGACAACGGTCGGCGG
GGGCGCGTGGTGGCGGGGGCCAACAACCGTCCCCTCAAGTCCCTCTCCGACATCATCGAAGGCAAACAGGGGCGCTTCCG
GCAAAACCTGTTGGGCAAACGGGTGGACTACTCCGGACGTTCGGTGATCGTGGTGGGGCCCAACCTGCGCATGCACCAGT
GTGGCCTGCCCAAAGAGATGGCCATCGAGCTGTTCCAGCCCTTTGTCATCCACAAATTGATCAAGCGGGGCATTGTCAAC
AACATCAAGGCTGCCAAAAAGATGATCCAGAGCAATGACCCACAGATTTGGGATGTGCTGGAAGAGGTGATCGACGGCCA
CCCCGTCTTGCTCAACCGTGCCCCCACCCTGCACCGCCTGGGGATCCAAGCTTTTGAGCCAATCCTGGTGGAGGGAAGGG
CGATTCAACTTCACCCTCTGGTTTGCCCCGCCTTCAATGCTGACTTCGACGGCGACCAGATGGCGGTGCATGTGCCCCTT
TCTCTGGAAGCTCAGGCGGAAGCTCGCCTGCTGATGCTGGCCACCAACAACATCCTCTCCCCTGCCACTGGCGCCCCTAT
CATCACCCCCAGCCAAGATATGGTGTTGGGGTGCTACTACCTGACGGCGGACAACCCCCACGCGCCAGATATTGGCGATC
GCTTCTTCGCCAGCTTGGAAGATGCTCTCATCGCCTACGACCGCGGCGCCATCGGCCTGCACAGCAAGGTCTGGGTGCGC
TACCACGGCCCGATGGAGTTGGGCAAGGGCGAAAAAGAGTCCGAGCCGCAAATTATCGAAGAAGCGGGCGGCATCCGCCT
CAAGATCACCAACTACCGCCGTATCCGCGAAGATCAAAACGGCAACGTGATCAGCCAGTACATTCGCACCACGCCGGGCC
GGATCATTTTTAACAAGACCGTGCAGGATATTTTGTCTGCGTAG

Upstream 100 bases:

>100_bases
CCCACCCCTGACGCGAACGTGACGGGGATCCCATTCAACCCACGAAGGAGGGTGGGGCTTCCCTCTCCTTTGGGTTCAGC
AAGCCAGGAGGAAAACGGCG

Downstream 100 bases:

>100_bases
TTACCCTCTGCCGTAGGACGGCTCTTCTCTCCCCTTCTCTCTAGCGAGGCATCATGAGCGAAAAAGGACGATTTTCCGCT
GGCCTGTCGCGGCAGGCTGC

Product: DNA-directed RNA polymerase subunit gamma

Products: NA

Alternate protein names: RNAP subunit gamma; RNA polymerase subunit gamma; Transcriptase subunit gamma [H]

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MAKTEQRFDYVKIGLASPERIMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCERIFGPAKDWECHCGKYKRVRH
RGIVCERCGVEVTESRVRRHRMGYIKLAAPVTHVWYLKGIPSHIATLLDMPLRDVEQVVYFNAYVVVDPGNAQNLSYKQL
LTEDQFLEIEDQMYEEGSELQLPENWAMIGAEAIERLLKDIDLEKEAEQLREEITSARGQKRARLIKRLRVIDNFIATGS
RPEWMVLRVLPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEIMAPEIIVRNEKRMLQEAVDALIDNGRR
GRVVAGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPNLRMHQCGLPKEMAIELFQPFVIHKLIKRGIVN
NIKAAKKMIQSNDPQIWDVLEEVIDGHPVLLNRAPTLHRLGIQAFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPL
SLEAQAEARLLMLATNNILSPATGAPIITPSQDMVLGCYYLTADNPHAPDIGDRFFASLEDALIAYDRGAIGLHSKVWVR
YHGPMELGKGEKESEPQIIEEAGGIRLKITNYRRIREDQNGNVISQYIRTTPGRIIFNKTVQDILSA

Sequences:

>Translated_627_residues
MAKTEQRFDYVKIGLASPERIMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCERIFGPAKDWECHCGKYKRVRH
RGIVCERCGVEVTESRVRRHRMGYIKLAAPVTHVWYLKGIPSHIATLLDMPLRDVEQVVYFNAYVVVDPGNAQNLSYKQL
LTEDQFLEIEDQMYEEGSELQLPENWAMIGAEAIERLLKDIDLEKEAEQLREEITSARGQKRARLIKRLRVIDNFIATGS
RPEWMVLRVLPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEIMAPEIIVRNEKRMLQEAVDALIDNGRR
GRVVAGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPNLRMHQCGLPKEMAIELFQPFVIHKLIKRGIVN
NIKAAKKMIQSNDPQIWDVLEEVIDGHPVLLNRAPTLHRLGIQAFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPL
SLEAQAEARLLMLATNNILSPATGAPIITPSQDMVLGCYYLTADNPHAPDIGDRFFASLEDALIAYDRGAIGLHSKVWVR
YHGPMELGKGEKESEPQIIEEAGGIRLKITNYRRIREDQNGNVISQYIRTTPGRIIFNKTVQDILSA
>Mature_626_residues
AKTEQRFDYVKIGLASPERIMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCERIFGPAKDWECHCGKYKRVRHR
GIVCERCGVEVTESRVRRHRMGYIKLAAPVTHVWYLKGIPSHIATLLDMPLRDVEQVVYFNAYVVVDPGNAQNLSYKQLL
TEDQFLEIEDQMYEEGSELQLPENWAMIGAEAIERLLKDIDLEKEAEQLREEITSARGQKRARLIKRLRVIDNFIATGSR
PEWMVLRVLPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEIMAPEIIVRNEKRMLQEAVDALIDNGRRG
RVVAGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPNLRMHQCGLPKEMAIELFQPFVIHKLIKRGIVNN
IKAAKKMIQSNDPQIWDVLEEVIDGHPVLLNRAPTLHRLGIQAFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPLS
LEAQAEARLLMLATNNILSPATGAPIITPSQDMVLGCYYLTADNPHAPDIGDRFFASLEDALIAYDRGAIGLHSKVWVRY
HGPMELGKGEKESEPQIIEEAGGIRLKITNYRRIREDQNGNVISQYIRTTPGRIIFNKTVQDILSA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=496, Percent_Identity=28.0241935483871, Blast_Score=166, Evalue=9e-41,
Organism=Homo sapiens, GI39725938, Length=324, Percent_Identity=31.4814814814815, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI103471997, Length=229, Percent_Identity=31.4410480349345, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI2367335, Length=560, Percent_Identity=64.1071428571429, Blast_Score=747, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=303, Percent_Identity=32.013201320132, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI25145495, Length=329, Percent_Identity=31.0030395136778, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6324690, Length=379, Percent_Identity=31.9261213720317, Blast_Score=151, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6320061, Length=327, Percent_Identity=33.6391437308869, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6324917, Length=305, Percent_Identity=25.2459016393443, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17530899, Length=490, Percent_Identity=26.3265306122449, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281360912, Length=223, Percent_Identity=34.9775784753363, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI17647875, Length=348, Percent_Identity=28.1609195402299, Blast_Score=110, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR012755 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 71193; Mature: 71062

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTEQRFDYVKIGLASPERIMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCER
CCCCHHCCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCHHHHHHHH
IFGPAKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVTHVWYLKGI
HCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCEEEEECCHHHHHHHCCC
PSHIATLLDMPLRDVEQVVYFNAYVVVDPGNAQNLSYKQLLTEDQFLEIEDQMYEEGSEL
HHHHHHHHHCCHHHHHHHHEEEEEEEECCCCCCCCCHHHHHCCCHHEEHHHHHHCCCCCC
QLPENWAMIGAEAIERLLKDIDLEKEAEQLREEITSARGQKRARLIKRLRVIDNFIATGS
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
RPEWMVLRVLPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEIMAPEIIV
CCCEEEEEEECCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCHHEE
RNEKRMLQEAVDALIDNGRRGRVVAGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGR
CCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCC
SVIVVGPNLRMHQCGLPKEMAIELFQPFVIHKLIKRGIVNNIKAAKKMIQSNDPQIWDVL
EEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EEVIDGHPVLLNRAPTLHRLGIQAFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPL
HHHHCCCCEEEECCCCHHHHCHHHHCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEECC
SLEAQAEARLLMLATNNILSPATGAPIITPSQDMVLGCYYLTADNPHAPDIGDRFFASLE
EECCCCCCEEEEEEECCCCCCCCCCCEECCCCCEEEEEEEEECCCCCCCCHHHHHHHHHH
DALIAYDRGAIGLHSKVWVRYHGPMELGKGEKESEPQIIEEAGGIRLKITNYRRIREDQN
HHHHEECCCCCCCCCEEEEEECCCHHCCCCCCCCCCHHHHHCCCEEEEEECCHHHHCCCC
GNVISQYIRTTPGRIIFNKTVQDILSA
CCHHHHHHHCCCCCEEEHHHHHHHHCC
>Mature Secondary Structure 
AKTEQRFDYVKIGLASPERIMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCER
CCCHHCCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCHHHHHHHH
IFGPAKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVTHVWYLKGI
HCCCCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCEEEEECCHHHHHHHCCC
PSHIATLLDMPLRDVEQVVYFNAYVVVDPGNAQNLSYKQLLTEDQFLEIEDQMYEEGSEL
HHHHHHHHHCCHHHHHHHHEEEEEEEECCCCCCCCCHHHHHCCCHHEEHHHHHHCCCCCC
QLPENWAMIGAEAIERLLKDIDLEKEAEQLREEITSARGQKRARLIKRLRVIDNFIATGS
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
RPEWMVLRVLPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEIMAPEIIV
CCCEEEEEEECCCCCCCCCEEEECCCEEECCHHHHHHHHHHCCCCHHHHHHHHHCCHHEE
RNEKRMLQEAVDALIDNGRRGRVVAGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGR
CCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCC
SVIVVGPNLRMHQCGLPKEMAIELFQPFVIHKLIKRGIVNNIKAAKKMIQSNDPQIWDVL
EEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EEVIDGHPVLLNRAPTLHRLGIQAFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPL
HHHHCCCCEEEECCCCHHHHCHHHHCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEECC
SLEAQAEARLLMLATNNILSPATGAPIITPSQDMVLGCYYLTADNPHAPDIGDRFFASLE
EECCCCCCEEEEEEECCCCCCCCCCCEECCCCCEEEEEEEEECCCCCCCCHHHHHHHHHH
DALIAYDRGAIGLHSKVWVRYHGPMELGKGEKESEPQIIEEAGGIRLKITNYRRIREDQN
HHHHEECCCCCCCCCEEEEEECCCHHCCCCCCCCCCHHHHHCCCEEEEEECCHHHHCCCC
GNVISQYIRTTPGRIIFNKTVQDILSA
CCHHHHHHHCCCCCEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA