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The map label for this gene is ppnK [H]

Identifier: 86609817

GI number: 86609817

Start: 2483164

End: 2484087

Strand: Direct

Name: ppnK [H]

Synonym: CYB_2378

Alternate gene names: 86609817

Gene position: 2483164-2484087 (Clockwise)

Preceding gene: 86609816

Following gene: 86609821

Centisome position: 81.5

GC content: 60.39

Gene sequence:

>924_bases
ATGACCAAGCCCAAAGCCGGGATCCTCTACAACGACGCCAAACCCGCCGCCAAACGCAGCAGCGAAACCCTAGCCCGCTG
GTTTCAGGAGCAGGGCTGGGAAGTCTGTGTGGCCCCCAACTGGGGCGGTATCCTCGGTTATGCCAAGCCCGACAGCCCCA
TCTGCCTGACCAAAGTAGATAGCCTGGCCCCGGCTGGATTTGATCAAACCATGAAGTTTGCGGTGGTGTTGGGGGGAGAT
GGCACCGTCTTGGCAGCAGCACGGCAACTGGCCCCCAAAGGGATCCCCTTGTTGGCGGTGAATACGGGCCATCTGGGCTT
TCTGACGGAGACCTACCTTCCTCACCTAGAAGAGGCAGCCAGTGCCGCCATTGCCGGGGAATACACCCTGGATCGCCGCA
GCATGTTGCTGGTGCAAGCCTACCGAGGGCAAGAATTGCGCTGGGAGGTCTTGAGCTTAAACGAGATGGTGCTGCACCGC
GAGCCTTTGACCAGCATGTGCCACTTCGAGATCACCATCGGGGATCACTCACCTCTGGATGTGGCTGCCGACGGAGTCAT
CTTGGCTACTCCCACCGGCTCGACGGCCTATGCCCTCTCGGCGGGTGGGCCGGTGATCACACCGGGGGTGCCGGTTTTGC
AGCTGATTCCCATCTGCCCCCATTCCATGGCGTCGCGGGCCTTGGTCTTCCCCGATTCGGAGGAGGTATGGATTAGCCCC
GTTACCCCTCAGCCACTGGTTTTGGTGGTAGATGGAAATGCCGGCTGCTACATCATGCCGGAAGACCAGATTCGGGTGGT
ACGTGCCCCCTATTGGACAGATTTGATGCGCCTGCGCCGACCGGAATTTTTCCGGGTTATGCGAGAGAAGTTGGGGTGGG
GACTGCCCCACGCTTCCAAGCCCACGTCGGTGGAGTTGCCTTAA

Upstream 100 bases:

>100_bases
CAGCGAAGTCTGCTGGCAGAAATTGTGGAATGGATCACCTGGCCAGCAGAGGGGCCTGCAGAACTGATAGAGTTTTGGCA
CCTCTGCCTTCCCATTGCCC

Downstream 100 bases:

>100_bases
CTTTGCCGAGGCAGGACAAGCCATAGCTGCAAAATGGCCAATGCCCTTAACAACTCCACCCCTCTGTCGCTATGATGGTT
AGGCTCGGAAGCGGATGTGG

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 1 [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTKPKAGILYNDAKPAAKRSSETLARWFQEQGWEVCVAPNWGGILGYAKPDSPICLTKVDSLAPAGFDQTMKFAVVLGGD
GTVLAAARQLAPKGIPLLAVNTGHLGFLTETYLPHLEEAASAAIAGEYTLDRRSMLLVQAYRGQELRWEVLSLNEMVLHR
EPLTSMCHFEITIGDHSPLDVAADGVILATPTGSTAYALSAGGPVITPGVPVLQLIPICPHSMASRALVFPDSEEVWISP
VTPQPLVLVVDGNAGCYIMPEDQIRVVRAPYWTDLMRLRRPEFFRVMREKLGWGLPHASKPTSVELP

Sequences:

>Translated_307_residues
MTKPKAGILYNDAKPAAKRSSETLARWFQEQGWEVCVAPNWGGILGYAKPDSPICLTKVDSLAPAGFDQTMKFAVVLGGD
GTVLAAARQLAPKGIPLLAVNTGHLGFLTETYLPHLEEAASAAIAGEYTLDRRSMLLVQAYRGQELRWEVLSLNEMVLHR
EPLTSMCHFEITIGDHSPLDVAADGVILATPTGSTAYALSAGGPVITPGVPVLQLIPICPHSMASRALVFPDSEEVWISP
VTPQPLVLVVDGNAGCYIMPEDQIRVVRAPYWTDLMRLRRPEFFRVMREKLGWGLPHASKPTSVELP
>Mature_306_residues
TKPKAGILYNDAKPAAKRSSETLARWFQEQGWEVCVAPNWGGILGYAKPDSPICLTKVDSLAPAGFDQTMKFAVVLGGDG
TVLAAARQLAPKGIPLLAVNTGHLGFLTETYLPHLEEAASAAIAGEYTLDRRSMLLVQAYRGQELRWEVLSLNEMVLHRE
PLTSMCHFEITIGDHSPLDVAADGVILATPTGSTAYALSAGGPVITPGVPVLQLIPICPHSMASRALVFPDSEEVWISPV
TPQPLVLVVDGNAGCYIMPEDQIRVVRAPYWTDLMRLRRPEFFRVMREKLGWGLPHASKPTSVELP

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=257, Percent_Identity=29.9610894941634, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI1788968, Length=288, Percent_Identity=31.5972222222222, Blast_Score=149, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320794, Length=251, Percent_Identity=30.2788844621514, Blast_Score=116, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6322509, Length=251, Percent_Identity=32.6693227091633, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6325068, Length=181, Percent_Identity=34.2541436464088, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI28573830, Length=221, Percent_Identity=32.1266968325792, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573828, Length=221, Percent_Identity=32.1266968325792, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI161077047, Length=221, Percent_Identity=32.1266968325792, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573832, Length=221, Percent_Identity=32.1266968325792, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573826, Length=221, Percent_Identity=32.1266968325792, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20129957, Length=246, Percent_Identity=30.0813008130081, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281363321, Length=246, Percent_Identity=30.0813008130081, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653422, Length=246, Percent_Identity=30.0813008130081, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281363323, Length=246, Percent_Identity=30.0813008130081, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653424, Length=246, Percent_Identity=30.0813008130081, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 33375; Mature: 33244

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPKAGILYNDAKPAAKRSSETLARWFQEQGWEVCVAPNWGGILGYAKPDSPICLTKVD
CCCCCCCEEECCCCCHHHCCHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCCEEEEECC
SLAPAGFDQTMKFAVVLGGDGTVLAAARQLAPKGIPLLAVNTGHLGFLTETYLPHLEEAA
CCCCCCCCCCEEEEEEECCCCCEEHHHHHCCCCCCEEEEEECCCCEEHHHHHHHHHHHHH
SAAIAGEYTLDRRSMLLVQAYRGQELRWEVLSLNEMVLHREPLTSMCHFEITIGDHSPLD
HHHCCCCEEECCHHEEEEEECCCCCEEEEEEEHHHHHHCCCCCCCEEEEEEEECCCCCCC
VAADGVILATPTGSTAYALSAGGPVITPGVPVLQLIPICPHSMASRALVFPDSEEVWISP
EECCCEEEECCCCCCEEEEECCCCEECCCCCHHHEECCCCHHHHCCEEECCCCCCEEEEC
VTPQPLVLVVDGNAGCYIMPEDQIRVVRAPYWTDLMRLRRPEFFRVMREKLGWGLPHASK
CCCCCEEEEEECCCCEEEECCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
PTSVELP
CCEECCC
>Mature Secondary Structure 
TKPKAGILYNDAKPAAKRSSETLARWFQEQGWEVCVAPNWGGILGYAKPDSPICLTKVD
CCCCCCEEECCCCCHHHCCHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCCEEEEECC
SLAPAGFDQTMKFAVVLGGDGTVLAAARQLAPKGIPLLAVNTGHLGFLTETYLPHLEEAA
CCCCCCCCCCEEEEEEECCCCCEEHHHHHCCCCCCEEEEEECCCCEEHHHHHHHHHHHHH
SAAIAGEYTLDRRSMLLVQAYRGQELRWEVLSLNEMVLHREPLTSMCHFEITIGDHSPLD
HHHCCCCEEECCHHEEEEEECCCCCEEEEEEEHHHHHHCCCCCCCEEEEEEEECCCCCCC
VAADGVILATPTGSTAYALSAGGPVITPGVPVLQLIPICPHSMASRALVFPDSEEVWISP
EECCCEEEECCCCCCEEEEECCCCEECCCCCHHHEECCCCHHHHCCEEECCCCCCEEEEC
VTPQPLVLVVDGNAGCYIMPEDQIRVVRAPYWTDLMRLRRPEFFRVMREKLGWGLPHASK
CCCCCEEEEEECCCCEEEECCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
PTSVELP
CCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA