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The map label for this gene is ahpC [C]

Identifier: 86609696

GI number: 86609696

Start: 2357237

End: 2357845

Strand: Reverse

Name: ahpC [C]

Synonym: CYB_2254

Alternate gene names: 86609696

Gene position: 2357845-2357237 (Counterclockwise)

Preceding gene: 86609698

Following gene: 86609694

Centisome position: 77.39

GC content: 57.14

Gene sequence:

>609_bases
ATGTCTCAGGAAGGATGCCTGCGAGTGGGGCAGCCCGCTCCCGATTTTTCGGCCACCGCCGTCTATGACATGGAATTCAA
GACGGTGAAGCTCTCCGACTACCGGGGTAAGAAGTATGTGGTGCTGTTCTTCTACCCCTTGGACTTCACCTTTGTCTGCC
CAACGGAGATCACGGCCTTTAGCGACCGCTATGACGACTTTGCCAAGCTGGATACCGAGATCCTGGGCGTCTCGGTGGAC
AGCGAATACTCTCACTTGGCCTGGATCCAGACCGACCGCAAAGCCGGAGGGGTGGGCGAGCTAAGGTATCCTCTGGTCTC
TGACCTGAAAAAGGAGATCAGCGCTGCCTACAATGTTCTGGATCCGGAGGCCGGTGTGGCGCTGCGCGGCCTGTTCATCA
TCGACAAAGAAGGGATCATCCAGCACGCCACCATTAACAACCTGGCCTTTGGCCGCAGTGTGGATGAAACCTTGCGCACC
CTGCAAGCTATCCAATACGTGCAATCTCACCCCGATGAAGTTTGCCCGGCCAACTGGCAGCCCGGCCAGAAAACCATGCA
CCCCGACCCAGTGAAATCCAAGGAGTTCTTCGCGGCGATTGCCAAGTAG

Upstream 100 bases:

>100_bases
TGGGATCCGTCGCTATCTATCGAGTTAAGGCAGAGTCATTATGAGTATGGTATGTTAGGTTTGGTTTACATTTGCACTTT
ACCGCAAGGAGCGTTGATTT

Downstream 100 bases:

>100_bases
GTTGGCCCAGATCCTGCCTCAGGGATCCCGGGCTTTTTCGGGTATGGCTCCAGCCCCGGGTGGGCTGGGGCTTTTCTTCG
CCAGGGGCAGCCCGACTCTT

Product: anti-oxidant AhpCTSA family protein

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MSQEGCLRVGQPAPDFSATAVYDMEFKTVKLSDYRGKKYVVLFFYPLDFTFVCPTEITAFSDRYDDFAKLDTEILGVSVD
SEYSHLAWIQTDRKAGGVGELRYPLVSDLKKEISAAYNVLDPEAGVALRGLFIIDKEGIIQHATINNLAFGRSVDETLRT
LQAIQYVQSHPDEVCPANWQPGQKTMHPDPVKSKEFFAAIAK

Sequences:

>Translated_202_residues
MSQEGCLRVGQPAPDFSATAVYDMEFKTVKLSDYRGKKYVVLFFYPLDFTFVCPTEITAFSDRYDDFAKLDTEILGVSVD
SEYSHLAWIQTDRKAGGVGELRYPLVSDLKKEISAAYNVLDPEAGVALRGLFIIDKEGIIQHATINNLAFGRSVDETLRT
LQAIQYVQSHPDEVCPANWQPGQKTMHPDPVKSKEFFAAIAK
>Mature_201_residues
SQEGCLRVGQPAPDFSATAVYDMEFKTVKLSDYRGKKYVVLFFYPLDFTFVCPTEITAFSDRYDDFAKLDTEILGVSVDS
EYSHLAWIQTDRKAGGVGELRYPLVSDLKKEISAAYNVLDPEAGVALRGLFIIDKEGIIQHATINNLAFGRSVDETLRTL
QAIQYVQSHPDEVCPANWQPGQKTMHPDPVKSKEFFAAIAK

Specific function: Reduces peroxides. May play an important role in eliminating peroxides generated during metabolism [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=194, Percent_Identity=60.3092783505155, Blast_Score=244, Evalue=4e-65,
Organism=Homo sapiens, GI4505591, Length=195, Percent_Identity=56.9230769230769, Blast_Score=234, Evalue=3e-62,
Organism=Homo sapiens, GI32455266, Length=195, Percent_Identity=56.9230769230769, Blast_Score=234, Evalue=3e-62,
Organism=Homo sapiens, GI32455264, Length=195, Percent_Identity=56.9230769230769, Blast_Score=234, Evalue=3e-62,
Organism=Homo sapiens, GI5802974, Length=192, Percent_Identity=56.7708333333333, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI32483377, Length=188, Percent_Identity=56.9148936170213, Blast_Score=226, Evalue=1e-59,
Organism=Homo sapiens, GI5453549, Length=190, Percent_Identity=55.7894736842105, Blast_Score=226, Evalue=1e-59,
Organism=Homo sapiens, GI33188454, Length=91, Percent_Identity=69.2307692307692, Blast_Score=131, Evalue=3e-31,
Organism=Homo sapiens, GI4758638, Length=192, Percent_Identity=28.6458333333333, Blast_Score=81, Evalue=5e-16,
Organism=Escherichia coli, GI1786822, Length=173, Percent_Identity=35.2601156069364, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32565831, Length=189, Percent_Identity=56.0846560846561, Blast_Score=218, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI193204376, Length=189, Percent_Identity=56.0846560846561, Blast_Score=218, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17554494, Length=189, Percent_Identity=50.2645502645503, Blast_Score=206, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI25153706, Length=190, Percent_Identity=26.8421052631579, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=195, Percent_Identity=50.2564102564103, Blast_Score=184, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320661, Length=189, Percent_Identity=49.2063492063492, Blast_Score=179, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6319407, Length=202, Percent_Identity=30.1980198019802, Blast_Score=102, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17738015, Length=196, Percent_Identity=59.1836734693878, Blast_Score=240, Evalue=4e-64,
Organism=Drosophila melanogaster, GI17157991, Length=190, Percent_Identity=55.7894736842105, Blast_Score=225, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24641739, Length=190, Percent_Identity=55.7894736842105, Blast_Score=225, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24656348, Length=190, Percent_Identity=55.7894736842105, Blast_Score=222, Evalue=1e-58,
Organism=Drosophila melanogaster, GI17864676, Length=190, Percent_Identity=55.7894736842105, Blast_Score=222, Evalue=1e-58,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=48.6910994764398, Blast_Score=197, Evalue=3e-51,
Organism=Drosophila melanogaster, GI17975518, Length=189, Percent_Identity=34.3915343915344, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24652434, Length=189, Percent_Identity=34.3915343915344, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24652436, Length=189, Percent_Identity=34.3915343915344, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24581278, Length=195, Percent_Identity=27.6923076923077, Blast_Score=93, Evalue=9e-20,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 22624; Mature: 22493

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQEGCLRVGQPAPDFSATAVYDMEFKTVKLSDYRGKKYVVLFFYPLDFTFVCPTEITAF
CCCCCCEECCCCCCCCCCEEEEEEEEEEEEEECCCCCEEEEEEEECCCEEEECCCHHHHH
SDRYDDFAKLDTEILGVSVDSEYSHLAWIQTDRKAGGVGELRYPLVSDLKKEISAAYNVL
HHCCHHHHHHCHHHEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCC
DPEAGVALRGLFIIDKEGIIQHATINNLAFGRSVDETLRTLQAIQYVQSHPDEVCPANWQ
CCCCCEEEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
PGQKTMHPDPVKSKEFFAAIAK
CCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SQEGCLRVGQPAPDFSATAVYDMEFKTVKLSDYRGKKYVVLFFYPLDFTFVCPTEITAF
CCCCCEECCCCCCCCCCEEEEEEEEEEEEEECCCCCEEEEEEEECCCEEEECCCHHHHH
SDRYDDFAKLDTEILGVSVDSEYSHLAWIQTDRKAGGVGELRYPLVSDLKKEISAAYNVL
HHCCHHHHHHCHHHEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCC
DPEAGVALRGLFIIDKEGIIQHATINNLAFGRSVDETLRTLQAIQYVQSHPDEVCPANWQ
CCCCCEEEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
PGQKTMHPDPVKSKEFFAAIAK
CCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]