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The map label for this gene is trpS [H]

Identifier: 86609660

GI number: 86609660

Start: 2322455

End: 2323450

Strand: Reverse

Name: trpS [H]

Synonym: CYB_2214

Alternate gene names: 86609660

Gene position: 2323450-2322455 (Counterclockwise)

Preceding gene: 86609664

Following gene: 86609658

Centisome position: 76.26

GC content: 57.23

Gene sequence:

>996_bases
ATGGCCAAGCCGCGCACCCTTTCTGGCATTCAGCCCTCTGGCGAACTGCATTTGGGCAATTACTTGGGGGCGATTAAGAA
TTGGGTGGCCGAGCAGGAGCACTACGAGAACTTTTTTTGCATCGTCGATCAACACGCCATCACCGTCCCTCAGGATCCCA
AGCTGCTGAGGGAGCGTACCCGTTCGCTGTTTGCCCTTTATTTGGCCTGCGGTCTCAGCCTGGAGCATTGCGTGCTATTC
GTCCAGTCCCACGTGCCTGCCCATACGGAGCTGGCCTGGCTGTTCAACACCATCACCCCCATGAACTGGGCGGAGCGCAT
GATCCAATACAAGGAGAAGAAGGAAAAACAGGGGGAGGAGACCAGCGTTGGCTTGTTCAGCTACCCGATTTTGCAGGCGG
CAGATATTTTGCTCTACCAGCCCAAGTATGTGCCGGTGGGGGAGGATCAGCGGCAGCATATTGAGCTGTGTCGGGATATT
GCCCGCCGCTTCAATGACCGTTTTGGAGAGGTGTTTCTGATCCCGGAGGCCCTGATTCGTCCGGAGGGGGCGCGGGTAAT
GAGCTTGACCGATGGTACGCGCAAGATGTCCAAGTCGGATCCCTCGGATTTCAGCCGTATTCATCTGCTGGATGACCCAG
ATACCATCCGCAAGAAGATCCAAAAATGCAAGACCGATCCCATTCGGGGCATTGCCTTTGACGATCCGGCTCGTCCCGAA
GCCCACAATTTGTTGACGATTTACATGCTCACCTCCGGCAAAAGCAAGGAGGTGGTGGCGGCTGAGTGTGCCGAGATGGG
GTGGGGGCAGTTCAAGCCCCTCCTTGCCGACAGCATCATCGCTGCCCTGGAGCCCATTCAGCAGCGCTACCGGGAACTGT
GGAGCAACCCCGACCACCTGCTCGTTCTGATACGGGAGAATGCCGCTAAGGCCCGTGCCATCGCCGAGCAAACGCTAAAA
ACGGTGAGAGAGGCTATGGGGTTCTTACCCCCCTGA

Upstream 100 bases:

>100_bases
TCCATCATGAACCAACGGGTTGCGCCTCTCTTGATATCCTGAAAAAGACTTTCCTTGCTCTTGTCCTCCGTCTTGTTGGC
GTTTGAGATCTGCTTTCCCT

Downstream 100 bases:

>100_bases
GGGATCCCTGCCCAAGCTTTGATGGGATCAGTCGGGGTTGCCATCGCGGATCTCGACGGTGCTCAAGGCGCTCACCAGCC
AGTCTAAACCCAGCTCTGAG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MAKPRTLSGIQPSGELHLGNYLGAIKNWVAEQEHYENFFCIVDQHAITVPQDPKLLRERTRSLFALYLACGLSLEHCVLF
VQSHVPAHTELAWLFNTITPMNWAERMIQYKEKKEKQGEETSVGLFSYPILQAADILLYQPKYVPVGEDQRQHIELCRDI
ARRFNDRFGEVFLIPEALIRPEGARVMSLTDGTRKMSKSDPSDFSRIHLLDDPDTIRKKIQKCKTDPIRGIAFDDPARPE
AHNLLTIYMLTSGKSKEVVAAECAEMGWGQFKPLLADSIIAALEPIQQRYRELWSNPDHLLVLIRENAAKARAIAEQTLK
TVREAMGFLPP

Sequences:

>Translated_331_residues
MAKPRTLSGIQPSGELHLGNYLGAIKNWVAEQEHYENFFCIVDQHAITVPQDPKLLRERTRSLFALYLACGLSLEHCVLF
VQSHVPAHTELAWLFNTITPMNWAERMIQYKEKKEKQGEETSVGLFSYPILQAADILLYQPKYVPVGEDQRQHIELCRDI
ARRFNDRFGEVFLIPEALIRPEGARVMSLTDGTRKMSKSDPSDFSRIHLLDDPDTIRKKIQKCKTDPIRGIAFDDPARPE
AHNLLTIYMLTSGKSKEVVAAECAEMGWGQFKPLLADSIIAALEPIQQRYRELWSNPDHLLVLIRENAAKARAIAEQTLK
TVREAMGFLPP
>Mature_330_residues
AKPRTLSGIQPSGELHLGNYLGAIKNWVAEQEHYENFFCIVDQHAITVPQDPKLLRERTRSLFALYLACGLSLEHCVLFV
QSHVPAHTELAWLFNTITPMNWAERMIQYKEKKEKQGEETSVGLFSYPILQAADILLYQPKYVPVGEDQRQHIELCRDIA
RRFNDRFGEVFLIPEALIRPEGARVMSLTDGTRKMSKSDPSDFSRIHLLDDPDTIRKKIQKCKTDPIRGIAFDDPARPEA
HNLLTIYMLTSGKSKEVVAAECAEMGWGQFKPLLADSIIAALEPIQQRYRELWSNPDHLLVLIRENAAKARAIAEQTLKT
VREAMGFLPP

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=329, Percent_Identity=40.7294832826748, Blast_Score=271, Evalue=8e-73,
Organism=Homo sapiens, GI41352700, Length=179, Percent_Identity=49.7206703910614, Blast_Score=194, Evalue=8e-50,
Organism=Escherichia coli, GI1789786, Length=333, Percent_Identity=45.945945945946, Blast_Score=298, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI71982800, Length=335, Percent_Identity=36.4179104477612, Blast_Score=206, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI71982793, Length=335, Percent_Identity=36.4179104477612, Blast_Score=204, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6320474, Length=343, Percent_Identity=37.0262390670554, Blast_Score=207, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24666151, Length=326, Percent_Identity=39.2638036809816, Blast_Score=249, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37720; Mature: 37589

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPRTLSGIQPSGELHLGNYLGAIKNWVAEQEHYENFFCIVDQHAITVPQDPKLLRERT
CCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEECCEEECCCCHHHHHHHH
RSLFALYLACGLSLEHCVLFVQSHVPAHTELAWLFNTITPMNWAERMIQYKEKKEKQGEE
HHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
TSVGLFSYPILQAADILLYQPKYVPVGEDQRQHIELCRDIARRFNDRFGEVFLIPEALIR
CCCCHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCHHHHC
PEGARVMSLTDGTRKMSKSDPSDFSRIHLLDDPDTIRKKIQKCKTDPIRGIAFDDPARPE
CCCCEEEEECCCHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
AHNLLTIYMLTSGKSKEVVAAECAEMGWGQFKPLLADSIIAALEPIQQRYRELWSNPDHL
CCCEEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LVLIRENAAKARAIAEQTLKTVREAMGFLPP
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AKPRTLSGIQPSGELHLGNYLGAIKNWVAEQEHYENFFCIVDQHAITVPQDPKLLRERT
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEECCEEECCCCHHHHHHHH
RSLFALYLACGLSLEHCVLFVQSHVPAHTELAWLFNTITPMNWAERMIQYKEKKEKQGEE
HHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
TSVGLFSYPILQAADILLYQPKYVPVGEDQRQHIELCRDIARRFNDRFGEVFLIPEALIR
CCCCHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCHHHHC
PEGARVMSLTDGTRKMSKSDPSDFSRIHLLDDPDTIRKKIQKCKTDPIRGIAFDDPARPE
CCCCEEEEECCCHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
AHNLLTIYMLTSGKSKEVVAAECAEMGWGQFKPLLADSIIAALEPIQQRYRELWSNPDHL
CCCEEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LVLIRENAAKARAIAEQTLKTVREAMGFLPP
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]