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The map label for this gene is mre11 [H]

Identifier: 86609421

GI number: 86609421

Start: 2070304

End: 2071596

Strand: Reverse

Name: mre11 [H]

Synonym: CYB_1971

Alternate gene names: 86609421

Gene position: 2071596-2070304 (Counterclockwise)

Preceding gene: 86609422

Following gene: 86609420

Centisome position: 68.0

GC content: 59.24

Gene sequence:

>1293_bases
ATGGCCTGCTCAACCTGCACATTTTTACACCTGGCCGATGTGCATCTGGGCTATGACCGCTACGACAGCCCGGAGCGGAG
CAAGGACTTCTTTTTGGCTTTTCGGGATGTTGTCCGGCGCTATGCCATTCAGGATCCGGTGGACTTTGTGCTCATCGCCG
GAGATCTGTTCGAGCATCGGCAGATTCAGCCCGGCGTTCTCAACCAAGCCCAGATCGTCTTGCGGGAGCTGCAGCAGGCC
GGGATTCCGGTGTTGGCCATCGAGGGCAACCACGACAACCGTCCCTATGGCGTGAAAACCAGTTGGCTGAGGTACTTGGC
CGATCACGGGGAGTTGATCCTGCTGGAGCCGGAAGCAGGGGAAGAGGGCCTGGAGTTGCGTCCCTGGGCGGGTGGGCGGG
GAGGGTATCTGGATTTGCCCTGTGGGGTGCGGGTGATCGGATCCCAGTGGTACGGATCGGCAGCTCCCAGGTCGATTGAG
CAGTTGGCGGCGGCCATTCGACGGTTGCCCCCCGGCCCAGAACGGGTGGTGTTGATGTTCCACCACGGTCTAGAAGGCCA
AATTGCCCGTTACCAAGGCGCTTTGCGCTACCGGGATCTGTTGCCCTTGCGGGAGGCAGGAGTGGGCTACCTGGCCTTGG
GACACATTCACAAAAGCTATTCCGAGGGGGGGTGGATCTTCAACCCGGGATCCCTGGAGGCCAACAGCACTGCCGAATGG
GACTTCCAACGGGGGGCCTATCGCGTCCGCTGGGGAGATGGCCCACCCCAAGCGGAGTTGGTGCAGGATTACCATCAGCG
GCCCCGCCGCCGGCTCTATCTGGAGGCCAAGGGCAGAGAAACCCCCGAACAGATTGCCGCAGCAGCCATTGCCTTGGCTA
AGGGATCCCGTTTTCAGGAAAGTGAGATGGAGCCGATGGTGGAGTTGCGGCTGGTGGGACAGGTGGGGTTCGCCAAGCAT
GAGCTGGATAGCCGCGCCCTACAGTGTCAAATTCAGCAGCTTACCGGCGCCTTGCTGGTTCTGTTTCGTTTTGAGGCCAA
TACTTTAGAGCTCGGGTCGGCTGCCCTTTCCTTGGAAGAAGAGGGGCAGAGGCTACAAATCGAAGAGAAAATCTACAGGG
ATCTGCTGAGCAGCCATGCCCACTACCGCAAACGCAGTGAAGAGCTAGCGCGGCTGCTTCTGGATCTTAAAGAAAAGGTT
TTGGATGGGCAAGGAGAATCTGAAGTGTATGCTCACCTAAGGGGAGCTTTTGATGCTCCGCATCGCTGTCGCGAATGGGG
AGCAGAAGACTGA

Upstream 100 bases:

>100_bases
GGGGCGAACCCGATGATTGAGAGGAAGGGATCCCTATATCTTGGGTAGGGAACAAGATGGGTTTGCTAAACTGTGGACAA
TTTGCCGAGGTGCTCTGGGG

Downstream 100 bases:

>100_bases
TTATGCGGATCCTCTCTCTCGCTTTACAAAACTTCAAATCTCATGAGGATGCCGTCTTCACGTTTGAGCCAGGTATTAAC
GCCATTTGCGGAGAAAACGG

Product: Ser/Thr protein phosphatase family protein

Products: NA

Alternate protein names: pfMre11 [H]

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MACSTCTFLHLADVHLGYDRYDSPERSKDFFLAFRDVVRRYAIQDPVDFVLIAGDLFEHRQIQPGVLNQAQIVLRELQQA
GIPVLAIEGNHDNRPYGVKTSWLRYLADHGELILLEPEAGEEGLELRPWAGGRGGYLDLPCGVRVIGSQWYGSAAPRSIE
QLAAAIRRLPPGPERVVLMFHHGLEGQIARYQGALRYRDLLPLREAGVGYLALGHIHKSYSEGGWIFNPGSLEANSTAEW
DFQRGAYRVRWGDGPPQAELVQDYHQRPRRRLYLEAKGRETPEQIAAAAIALAKGSRFQESEMEPMVELRLVGQVGFAKH
ELDSRALQCQIQQLTGALLVLFRFEANTLELGSAALSLEEEGQRLQIEEKIYRDLLSSHAHYRKRSEELARLLLDLKEKV
LDGQGESEVYAHLRGAFDAPHRCREWGAED

Sequences:

>Translated_430_residues
MACSTCTFLHLADVHLGYDRYDSPERSKDFFLAFRDVVRRYAIQDPVDFVLIAGDLFEHRQIQPGVLNQAQIVLRELQQA
GIPVLAIEGNHDNRPYGVKTSWLRYLADHGELILLEPEAGEEGLELRPWAGGRGGYLDLPCGVRVIGSQWYGSAAPRSIE
QLAAAIRRLPPGPERVVLMFHHGLEGQIARYQGALRYRDLLPLREAGVGYLALGHIHKSYSEGGWIFNPGSLEANSTAEW
DFQRGAYRVRWGDGPPQAELVQDYHQRPRRRLYLEAKGRETPEQIAAAAIALAKGSRFQESEMEPMVELRLVGQVGFAKH
ELDSRALQCQIQQLTGALLVLFRFEANTLELGSAALSLEEEGQRLQIEEKIYRDLLSSHAHYRKRSEELARLLLDLKEKV
LDGQGESEVYAHLRGAFDAPHRCREWGAED
>Mature_429_residues
ACSTCTFLHLADVHLGYDRYDSPERSKDFFLAFRDVVRRYAIQDPVDFVLIAGDLFEHRQIQPGVLNQAQIVLRELQQAG
IPVLAIEGNHDNRPYGVKTSWLRYLADHGELILLEPEAGEEGLELRPWAGGRGGYLDLPCGVRVIGSQWYGSAAPRSIEQ
LAAAIRRLPPGPERVVLMFHHGLEGQIARYQGALRYRDLLPLREAGVGYLALGHIHKSYSEGGWIFNPGSLEANSTAEWD
FQRGAYRVRWGDGPPQAELVQDYHQRPRRRLYLEAKGRETPEQIAAAAIALAKGSRFQESEMEPMVELRLVGQVGFAKHE
LDSRALQCQIQQLTGALLVLFRFEANTLELGSAALSLEEEGQRLQIEEKIYRDLLSSHAHYRKRSEELARLLLDLKEKVL
DGQGESEVYAHLRGAFDAPHRCREWGAED

Specific function: Involved in DNA double-strand break repair (DSBR). The rad50/mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity [H]

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MRE11/RAD32 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003701
- InterPro:   IPR004843
- InterPro:   IPR004593 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 48538; Mature: 48406

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACSTCTFLHLADVHLGYDRYDSPERSKDFFLAFRDVVRRYAIQDPVDFVLIAGDLFEHR
CCCCHHHHEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHC
QIQPGVLNQAQIVLRELQQAGIPVLAIEGNHDNRPYGVKTSWLRYLADHGELILLEPEAG
CCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCC
EEGLELRPWAGGRGGYLDLPCGVRVIGSQWYGSAAPRSIEQLAAAIRRLPPGPERVVLMF
CCCCEECCCCCCCCCEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
HHGLEGQIARYQGALRYRDLLPLREAGVGYLALGHIHKSYSEGGWIFNPGSLEANSTAEW
ECCCCCHHHHHHHHHHHHHCCCHHHCCCCEEEEHHHHHHHCCCCEEECCCCCCCCCCCCC
DFQRGAYRVRWGDGPPQAELVQDYHQRPRRRLYLEAKGRETPEQIAAAAIALAKGSRFQE
HHCCCEEEEEECCCCCHHHHHHHHHHCHHHEEEEEECCCCCHHHHHHHHHHHHCCCCCCH
SEMEPMVELRLVGQVGFAKHELDSRALQCQIQQLTGALLVLFRFEANTLELGSAALSLEE
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEECCHHHCCHHH
EGQRLQIEEKIYRDLLSSHAHYRKRSEELARLLLDLKEKVLDGQGESEVYAHLRGAFDAP
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
HRCREWGAED
HHHHHCCCCC
>Mature Secondary Structure 
ACSTCTFLHLADVHLGYDRYDSPERSKDFFLAFRDVVRRYAIQDPVDFVLIAGDLFEHR
CCCHHHHEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHC
QIQPGVLNQAQIVLRELQQAGIPVLAIEGNHDNRPYGVKTSWLRYLADHGELILLEPEAG
CCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCC
EEGLELRPWAGGRGGYLDLPCGVRVIGSQWYGSAAPRSIEQLAAAIRRLPPGPERVVLMF
CCCCEECCCCCCCCCEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
HHGLEGQIARYQGALRYRDLLPLREAGVGYLALGHIHKSYSEGGWIFNPGSLEANSTAEW
ECCCCCHHHHHHHHHHHHHCCCHHHCCCCEEEEHHHHHHHCCCCEEECCCCCCCCCCCCC
DFQRGAYRVRWGDGPPQAELVQDYHQRPRRRLYLEAKGRETPEQIAAAAIALAKGSRFQE
HHCCCEEEEEECCCCCHHHHHHHHHHCHHHEEEEEECCCCCHHHHHHHHHHHHCCCCCCH
SEMEPMVELRLVGQVGFAKHELDSRALQCQIQQLTGALLVLFRFEANTLELGSAALSLEE
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEECCHHHCCHHH
EGQRLQIEEKIYRDLLSSHAHYRKRSEELARLLLDLKEKVLDGQGESEVYAHLRGAFDAP
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
HRCREWGAED
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11029422 [H]