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The map label for this gene is ag45 [H]

Identifier: 86609359

GI number: 86609359

Start: 1988656

End: 1989891

Strand: Direct

Name: ag45 [H]

Synonym: CYB_1903

Alternate gene names: 86609359

Gene position: 1988656-1989891 (Clockwise)

Preceding gene: 86609357

Following gene: 86609360

Centisome position: 65.27

GC content: 59.63

Gene sequence:

>1236_bases
GTGCAGGGGCTGTCTTGGTTGGTGTTGGGTTTGAGCTATGTCGGGTTGGGACTGGGATCCCTGCCTAGGTTGCGTATGAA
CCGGGCCACCATCGCCCTGGTGGGATCCGCCCTGTTGATTGGCTTGGGGACCTTGTCGCTACGGCAGGCTTGGGAAGCCA
TTGACCCGACCACGATTGTGTTTCTCCTGAGCATGATGGTGGTAAATGCCAGCTTGTCCTATGGGGGGGCTTTTCAGTTG
GCTTTGCTGGGCTTGATTCGGGTGAGCCGCAGCCCCTTTGGTCTGTTGATCATGCTGGTGTTCGGCAGCGGGCTGCTCTC
GGCTTTCCTGCTCAACGACACGCTGGCGCTGGTATTCACCCCCCTAACTTTGCAAGTCACAACGGTGTTGGGGTTAAACC
CGATCCCCTACCTGCTGGGCTTGGCGGCAGCCACCAACCTGGGATCCGTCGCCACCCTGAGCGGCAACCCGCAGAATATC
CTGATCGGCTCCTTCTCTGGGATCGGCTACCTGGAGTTTGCTGCCCAGATGACCCCCATTGCCGTGGTGGGGCTGCTGCT
GGAAGTGGGGTTGCTGTGGCTGTACTACCCTGAGGTGCGCTCGTTGAAACCCTTTGCTCGGGTGCCTTGGCTGCCGCTGC
GGCTCTACCCGCCCCTGTTGCGCAAGAGCGTGGTGATTACGGGGGGGCTGTTTGTGGCCTTTGTAGCCGGACTTCCCTTG
GCAGAATCGGCCTTGGTGGCGGCAGCCCTGTTGTTGATTACCCGCAGGCTGAAGCCGGAGCGATTTTTGGGGCAGGTGGA
CTGGAATCTGCTGGTGATGTTTTCCGGGCTATTTATCCTGACGCGGGCAACGGGAGAGCTGGTAACTGTTTGGGGGATGA
GCTTGGGATCCTTGGCAGAGAGTCTGGCGGGATCCCCTCTTGCCCTGCTGAGTAGTGTGGCCGTTTTATCCAACCTCATC
TCCAATGTGCCGGCGGTGCTGTTGCTGCAATCGTTCCTGCCTCGGCAGGAGACCACCGCTTGGCTGTTGCTGGCTGCCGG
CTCCACTTTGGCGGGCAATTTGACTCTATTTGGGGCGGTGGCCAATCTGATCACGGTTGAGGCAGCGGCCAAAAAAGGCT
ACGTGCTCTCGTTTGGGGAACATCTGCGCTTTGGCCTGCCCCTCACTCTCCTAACCCTGGGGTTCAGTGGGTTGTGGCTG
TGCCAGCCTTTCCTGTCTTCTCCACCGCTCAGATGA

Upstream 100 bases:

>100_bases
TTCATTGAGTATCGGGAATGTTGGGCCTGTTTCAACTCCAGCCTTTGCCATTGGCTGAACCCATCAGGGATCCTGAAAGA
AGTGCGGGAGGGATCGGGGG

Downstream 100 bases:

>100_bases
CCTCTGTCGAGGGATCCAGTGGGGCTGTGACTGGCTTGTCGGGATCCCTGTGTATGATGGGAAAAAGAGTTTAAGAAACG
TAACGTGTCTTCTCCGCTAT

Product: arsenite-antimonite (ArsAB) efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MQGLSWLVLGLSYVGLGLGSLPRLRMNRATIALVGSALLIGLGTLSLRQAWEAIDPTTIVFLLSMMVVNASLSYGGAFQL
ALLGLIRVSRSPFGLLIMLVFGSGLLSAFLLNDTLALVFTPLTLQVTTVLGLNPIPYLLGLAAATNLGSVATLSGNPQNI
LIGSFSGIGYLEFAAQMTPIAVVGLLLEVGLLWLYYPEVRSLKPFARVPWLPLRLYPPLLRKSVVITGGLFVAFVAGLPL
AESALVAAALLLITRRLKPERFLGQVDWNLLVMFSGLFILTRATGELVTVWGMSLGSLAESLAGSPLALLSSVAVLSNLI
SNVPAVLLLQSFLPRQETTAWLLLAAGSTLAGNLTLFGAVANLITVEAAAKKGYVLSFGEHLRFGLPLTLLTLGFSGLWL
CQPFLSSPPLR

Sequences:

>Translated_411_residues
MQGLSWLVLGLSYVGLGLGSLPRLRMNRATIALVGSALLIGLGTLSLRQAWEAIDPTTIVFLLSMMVVNASLSYGGAFQL
ALLGLIRVSRSPFGLLIMLVFGSGLLSAFLLNDTLALVFTPLTLQVTTVLGLNPIPYLLGLAAATNLGSVATLSGNPQNI
LIGSFSGIGYLEFAAQMTPIAVVGLLLEVGLLWLYYPEVRSLKPFARVPWLPLRLYPPLLRKSVVITGGLFVAFVAGLPL
AESALVAAALLLITRRLKPERFLGQVDWNLLVMFSGLFILTRATGELVTVWGMSLGSLAESLAGSPLALLSSVAVLSNLI
SNVPAVLLLQSFLPRQETTAWLLLAAGSTLAGNLTLFGAVANLITVEAAAKKGYVLSFGEHLRFGLPLTLLTLGFSGLWL
CQPFLSSPPLR
>Mature_411_residues
MQGLSWLVLGLSYVGLGLGSLPRLRMNRATIALVGSALLIGLGTLSLRQAWEAIDPTTIVFLLSMMVVNASLSYGGAFQL
ALLGLIRVSRSPFGLLIMLVFGSGLLSAFLLNDTLALVFTPLTLQVTTVLGLNPIPYLLGLAAATNLGSVATLSGNPQNI
LIGSFSGIGYLEFAAQMTPIAVVGLLLEVGLLWLYYPEVRSLKPFARVPWLPLRLYPPLLRKSVVITGGLFVAFVAGLPL
AESALVAAALLLITRRLKPERFLGQVDWNLLVMFSGLFILTRATGELVTVWGMSLGSLAESLAGSPLALLSSVAVLSNLI
SNVPAVLLLQSFLPRQETTAWLLLAAGSTLAGNLTLFGAVANLITVEAAAKKGYVLSFGEHLRFGLPLTLLTLGFSGLWL
CQPFLSSPPLR

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Homo sapiens, GI157266326, Length=138, Percent_Identity=36.231884057971, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787039, Length=350, Percent_Identity=30, Blast_Score=93, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24581759, Length=167, Percent_Identity=32.3353293413174, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28574683, Length=167, Percent_Identity=32.3353293413174, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28574681, Length=167, Percent_Identity=32.3353293413174, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28574685, Length=167, Percent_Identity=32.3353293413174, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28574678, Length=167, Percent_Identity=32.3353293413174, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19920704, Length=167, Percent_Identity=32.3353293413174, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 43564; Mature: 43564

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGLSWLVLGLSYVGLGLGSLPRLRMNRATIALVGSALLIGLGTLSLRQAWEAIDPTTIV
CCCHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
FLLSMMVVNASLSYGGAFQLALLGLIRVSRSPFGLLIMLVFGSGLLSAFLLNDTLALVFT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHEE
PLTLQVTTVLGLNPIPYLLGLAAATNLGSVATLSGNPQNILIGSFSGIGYLEFAAQMTPI
CHHEEEEHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHH
AVVGLLLEVGLLWLYYPEVRSLKPFARVPWLPLRLYPPLLRKSVVITGGLFVAFVAGLPL
HHHHHHHHHHHHHHCCCHHHCCCCHHHCCCCCHHCCCHHHHCCCEEECHHHHHHHHCCCC
AESALVAAALLLITRRLKPERFLGQVDWNLLVMFSGLFILTRATGELVTVWGMSLGSLAE
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHEEECCCCEEEECCCCHHHHHH
SLAGSPLALLSSVAVLSNLISNVPAVLLLQSFLPRQETTAWLLLAAGSTLAGNLTLFGAV
HHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHH
ANLITVEAAAKKGYVLSFGEHLRFGLPLTLLTLGFSGLWLCQPFLSSPPLR
HHHHHHHHHHCCCEEEECCCHHHCCCCHHHHHHCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQGLSWLVLGLSYVGLGLGSLPRLRMNRATIALVGSALLIGLGTLSLRQAWEAIDPTTIV
CCCHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
FLLSMMVVNASLSYGGAFQLALLGLIRVSRSPFGLLIMLVFGSGLLSAFLLNDTLALVFT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHEE
PLTLQVTTVLGLNPIPYLLGLAAATNLGSVATLSGNPQNILIGSFSGIGYLEFAAQMTPI
CHHEEEEHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHH
AVVGLLLEVGLLWLYYPEVRSLKPFARVPWLPLRLYPPLLRKSVVITGGLFVAFVAGLPL
HHHHHHHHHHHHHHCCCHHHCCCCHHHCCCCCHHCCCHHHHCCCEEECHHHHHHHHCCCC
AESALVAAALLLITRRLKPERFLGQVDWNLLVMFSGLFILTRATGELVTVWGMSLGSLAE
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHEEECCCCEEEECCCCHHHHHH
SLAGSPLALLSSVAVLSNLISNVPAVLLLQSFLPRQETTAWLLLAAGSTLAGNLTLFGAV
HHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHH
ANLITVEAAAKKGYVLSFGEHLRFGLPLTLLTLGFSGLWLCQPFLSSPPLR
HHHHHHHHHHCCCEEEECCCHHHCCCCHHHHHHCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]