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The map label for this gene is cysS

Identifier: 86609278

GI number: 86609278

Start: 1909095

End: 1910672

Strand: Direct

Name: cysS

Synonym: CYB_1821

Alternate gene names: 86609278

Gene position: 1909095-1910672 (Clockwise)

Preceding gene: 86609273

Following gene: 86609279

Centisome position: 62.66

GC content: 55.96

Gene sequence:

>1578_bases
TTGGTTGTCTATAACACATTGACTCGCCGCAAGGAAGTGTTTCAGCCGCTGGCAGCAGGTGGATCTCAATCCGTTTCCGT
CGGCAATTCCCAGGGATCTGCAGCTCCAGTTGCGGAGGAGAAGCCCCTGGTGCGGATGTATGTCTGTGGTGTAACGGTTT
ACGACCTCTGCCACCTCGGCCATGCGCGTACCTACGTGGTTTGGGACATGGTGCGTCGCTACTTGGAGTGGCGCGGCTAC
CGAGTGAAGTATGTGCAGAATTTTACCGATGTGGACGACAAGATCCTCAAGCGGGCGTTGGAACGTGGCGAATCCATGCA
AGCGGTGGCGGAGCGCTTCATCGCCGAGTATTTCCGAGATATGGATTGCCTGAACATCAAGCGGGCCGATTTCTACCCGA
GGGCAACGCAATCGCTGCAAGCCATGTTCCAGTTGATCCAATCTTTGGAGCTCAAAGGCTTTGCCTACCGGGTACGGGAT
CCCATTCGACACCAGACCGACCAGTCTTCCCTCCTGCAAGCGGGACACCAGCCAGAGACCCCCGCCTCTGTTCAGTACTC
TGTTTACTACTCTGTCCGCAAGTTCCCGGATTACGGCCAGCTATCCGGTCGAAAACTGGAGGAGATGGAGGCGGGAGCCA
GTGGCCGGGTAGGAGAAGAAGGAGCTGAGAAACAGGATCCCTTCGACTTTGCCCTTTGGAAAGCGGCCCCCCCTTCTGAG
CCGGGGTTTGCCTCCCCTTGGGGTTGGGGGCGACCGGGCTGGCACATCGAATGTTCCGCCATGGTGCGGGAGACCCTGGG
AGATCACATCGACATTCACGCCGGCGGGGCAGATTTGATTTTCCCCCACCACGAAAATGAGCTGGCCCAATCGGAGCCAA
TCACCGGCAAGCCGATGGCCAAGTACTGGATGCACAACGGTTTTCTCAACATCAACGGCGAGAAAATGTCCAAATCTTTG
GGCAACTTCACCACCCTGCGACAGGCCCTCGCCGTCTATCACCCCATGGCCTTGCGGCTGTTTCTGTTGCAGACCCACTA
CCGTAGCCCCATAGATCTCACCGAGGCAGCCATGCAGGCGGCTAGCCGTGGCTGGGAAACCCTCCAGAAAGGGATCCACT
GTGCCCAGCACTTCTGCAAAGAAGAAAAGGGATCCCCTGATGCTGAGGCCATGCAAGCCTTTCAAGCTGCTATGGACAAT
GATTTTGGCACCCCTGAAGCGCTGGCTATCGCCTTTGAATTGGCCAAAGAACTCACCCGCGAACACAACCTGTTCACCCA
TCAAGGCCAAACCCATCTGGAGCCCCAGGCCCTCAAACAAAAAAGCGCTGCCTTGCTGGAGATTTTGGCTACTTTGGGAT
TCTGTTGGCCCTCATTCTCTGAATTCGAGGGATCCAAAGAAGCAGCTACAAATGGGGAACTTAACTTTAAAAAAATCGAG
GAGCTGATCGCGCAGCGCTCGGCAGCCCGTAAGGCGAAAAACTTTTCAGAGGCAGATCGCATTCGGGATCAGTTGAAAGC
CCTGGGCATCACCCTCATCGATCAAAAAGATGGCACCACCCGTTGGCTGCGAGAATAG

Upstream 100 bases:

>100_bases
AGCCTCATCCGATTCAAGACAAAGTGCGCCATCGTCTTTTTTTGGAAGACAAAGCCTGTTTTGCTGTAGCTGAAACTACA
AACTAGGGATACCCATGGAT

Downstream 100 bases:

>100_bases
GGGTTGAGGAGCATTCCTCGGGCTCATTCAAAATGGATGTGGCTGTAACCTAGGGGCTCAGAGGGGCAAAGTGCTTCTCC
CTTCGTTTGGGTTGCTGGAA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MVVYNTLTRRKEVFQPLAAGGSQSVSVGNSQGSAAPVAEEKPLVRMYVCGVTVYDLCHLGHARTYVVWDMVRRYLEWRGY
RVKYVQNFTDVDDKILKRALERGESMQAVAERFIAEYFRDMDCLNIKRADFYPRATQSLQAMFQLIQSLELKGFAYRVRD
PIRHQTDQSSLLQAGHQPETPASVQYSVYYSVRKFPDYGQLSGRKLEEMEAGASGRVGEEGAEKQDPFDFALWKAAPPSE
PGFASPWGWGRPGWHIECSAMVRETLGDHIDIHAGGADLIFPHHENELAQSEPITGKPMAKYWMHNGFLNINGEKMSKSL
GNFTTLRQALAVYHPMALRLFLLQTHYRSPIDLTEAAMQAASRGWETLQKGIHCAQHFCKEEKGSPDAEAMQAFQAAMDN
DFGTPEALAIAFELAKELTREHNLFTHQGQTHLEPQALKQKSAALLEILATLGFCWPSFSEFEGSKEAATNGELNFKKIE
ELIAQRSAARKAKNFSEADRIRDQLKALGITLIDQKDGTTRWLRE

Sequences:

>Translated_525_residues
MVVYNTLTRRKEVFQPLAAGGSQSVSVGNSQGSAAPVAEEKPLVRMYVCGVTVYDLCHLGHARTYVVWDMVRRYLEWRGY
RVKYVQNFTDVDDKILKRALERGESMQAVAERFIAEYFRDMDCLNIKRADFYPRATQSLQAMFQLIQSLELKGFAYRVRD
PIRHQTDQSSLLQAGHQPETPASVQYSVYYSVRKFPDYGQLSGRKLEEMEAGASGRVGEEGAEKQDPFDFALWKAAPPSE
PGFASPWGWGRPGWHIECSAMVRETLGDHIDIHAGGADLIFPHHENELAQSEPITGKPMAKYWMHNGFLNINGEKMSKSL
GNFTTLRQALAVYHPMALRLFLLQTHYRSPIDLTEAAMQAASRGWETLQKGIHCAQHFCKEEKGSPDAEAMQAFQAAMDN
DFGTPEALAIAFELAKELTREHNLFTHQGQTHLEPQALKQKSAALLEILATLGFCWPSFSEFEGSKEAATNGELNFKKIE
ELIAQRSAARKAKNFSEADRIRDQLKALGITLIDQKDGTTRWLRE
>Mature_525_residues
MVVYNTLTRRKEVFQPLAAGGSQSVSVGNSQGSAAPVAEEKPLVRMYVCGVTVYDLCHLGHARTYVVWDMVRRYLEWRGY
RVKYVQNFTDVDDKILKRALERGESMQAVAERFIAEYFRDMDCLNIKRADFYPRATQSLQAMFQLIQSLELKGFAYRVRD
PIRHQTDQSSLLQAGHQPETPASVQYSVYYSVRKFPDYGQLSGRKLEEMEAGASGRVGEEGAEKQDPFDFALWKAAPPSE
PGFASPWGWGRPGWHIECSAMVRETLGDHIDIHAGGADLIFPHHENELAQSEPITGKPMAKYWMHNGFLNINGEKMSKSL
GNFTTLRQALAVYHPMALRLFLLQTHYRSPIDLTEAAMQAASRGWETLQKGIHCAQHFCKEEKGSPDAEAMQAFQAAMDN
DFGTPEALAIAFELAKELTREHNLFTHQGQTHLEPQALKQKSAALLEILATLGFCWPSFSEFEGSKEAATNGELNFKKIE
ELIAQRSAARKAKNFSEADRIRDQLKALGITLIDQKDGTTRWLRE

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI13375695, Length=556, Percent_Identity=31.294964028777, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI10835051, Length=258, Percent_Identity=36.046511627907, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI21269877, Length=258, Percent_Identity=36.046511627907, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI303304987, Length=258, Percent_Identity=36.046511627907, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI62240992, Length=258, Percent_Identity=36.046511627907, Blast_Score=160, Evalue=3e-39,
Organism=Escherichia coli, GI1786737, Length=525, Percent_Identity=41.3333333333333, Blast_Score=354, Evalue=7e-99,
Organism=Caenorhabditis elegans, GI17509795, Length=292, Percent_Identity=33.2191780821918, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17509797, Length=292, Percent_Identity=33.2191780821918, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6324082, Length=389, Percent_Identity=29.5629820051414, Blast_Score=160, Evalue=3e-40,
Organism=Drosophila melanogaster, GI19922218, Length=525, Percent_Identity=30.8571428571429, Blast_Score=198, Evalue=8e-51,
Organism=Drosophila melanogaster, GI19922364, Length=365, Percent_Identity=30.4109589041096, Blast_Score=159, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYC_SYNJB (Q2JKL2)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_478040.1
- ProteinModelPortal:   Q2JKL2
- SMR:   Q2JKL2
- STRING:   Q2JKL2
- GeneID:   3901204
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_1821
- TIGR:   CYB_1821
- eggNOG:   COG0215
- HOGENOM:   HBG327651
- OMA:   FTADAIN
- PhylomeDB:   Q2JKL2
- ProtClustDB:   PRK00260
- BioCyc:   SSP321332:CYB_1821-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00041_B
- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10890
- PRINTS:   PR00983
- SMART:   SM00840
- TIGRFAMs:   TIGR00435

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.16

Molecular weight: Translated: 59249; Mature: 59249

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 318-318

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVYNTLTRRKEVFQPLAAGGSQSVSVGNSQGSAAPVAEEKPLVRMYVCGVTVYDLCHLG
CEEEHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCC
HARTYVVWDMVRRYLEWRGYRVKYVQNFTDVDDKILKRALERGESMQAVAERFIAEYFRD
CCHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
MDCLNIKRADFYPRATQSLQAMFQLIQSLELKGFAYRVRDPIRHQTDQSSLLQAGHQPET
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHCCCHHHHHHCCCCCCC
PASVQYSVYYSVRKFPDYGQLSGRKLEEMEAGASGRVGEEGAEKQDPFDFALWKAAPPSE
CCCEEEEEEEHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
PGFASPWGWGRPGWHIECSAMVRETLGDHIDIHAGGADLIFPHHENELAQSEPITGKPMA
CCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEEECCCCCEECCCCCCHHHCCCCCCCCHHH
KYWMHNGFLNINGEKMSKSLGNFTTLRQALAVYHPMALRLFLLQTHYRSPIDLTEAAMQA
HHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ASRGWETLQKGIHCAQHFCKEEKGSPDAEAMQAFQAAMDNDFGTPEALAIAFELAKELTR
HHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EHNLFTHQGQTHLEPQALKQKSAALLEILATLGFCWPSFSEFEGSKEAATNGELNFKKIE
HCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHCCCCCCCHHHHH
ELIAQRSAARKAKNFSEADRIRDQLKALGITLIDQKDGTTRWLRE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCHHHHCC
>Mature Secondary Structure
MVVYNTLTRRKEVFQPLAAGGSQSVSVGNSQGSAAPVAEEKPLVRMYVCGVTVYDLCHLG
CEEEHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCC
HARTYVVWDMVRRYLEWRGYRVKYVQNFTDVDDKILKRALERGESMQAVAERFIAEYFRD
CCHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
MDCLNIKRADFYPRATQSLQAMFQLIQSLELKGFAYRVRDPIRHQTDQSSLLQAGHQPET
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHCCCHHHHHHCCCCCCC
PASVQYSVYYSVRKFPDYGQLSGRKLEEMEAGASGRVGEEGAEKQDPFDFALWKAAPPSE
CCCEEEEEEEHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
PGFASPWGWGRPGWHIECSAMVRETLGDHIDIHAGGADLIFPHHENELAQSEPITGKPMA
CCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEEECCCCCEECCCCCCHHHCCCCCCCCHHH
KYWMHNGFLNINGEKMSKSLGNFTTLRQALAVYHPMALRLFLLQTHYRSPIDLTEAAMQA
HHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ASRGWETLQKGIHCAQHFCKEEKGSPDAEAMQAFQAAMDNDFGTPEALAIAFELAKELTR
HHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EHNLFTHQGQTHLEPQALKQKSAALLEILATLGFCWPSFSEFEGSKEAATNGELNFKKIE
HCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHCCCCCCCHHHHH
ELIAQRSAARKAKNFSEADRIRDQLKALGITLIDQKDGTTRWLRE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA