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The map label for this gene is thyX [H]

Identifier: 86609239

GI number: 86609239

Start: 1866870

End: 1867760

Strand: Direct

Name: thyX [H]

Synonym: CYB_1781

Alternate gene names: 86609239

Gene position: 1866870-1867760 (Clockwise)

Preceding gene: 86609238

Following gene: 86609240

Centisome position: 61.28

GC content: 53.98

Gene sequence:

>891_bases
GTGGATGCTTTGTTTCAAGTTGTGGTGCTGAATCAAACCCCAGATCCAGAACGGGTCATCTACCAGGCAATGCACCAGGA
TTACAGCCCTGATTTTGTCACCTCAGAAAGCCGGATCCCGGAAAAGTATGGAGAGGCGGTGGTGCGGCATTTGCTGGAGG
GCAACCGTGGCCACTATGGGCCTCTAGAGCATCCTCAGATCACCTTTGGGGTGGGCTATTTTCCCCACGCCGTCATGCAA
CAGGCCCGTACTCATCGGGTGGGAATTTCTTTTGATGTTCAATCCTTCCGATATACAGGCCAGCAAATTGCCGATTTGGG
CAAAAAGCTCTTGTTCGCGTCAGCGGTGCGGAGCACAACCGAGACTGCTGCTCCTGTTGGCGAGACCGGCTACGGTTGCG
TCAGCGATCGCGTCAGCGGGCCGGAGGCCTATCGCGACAGCGGTGCGGAGCACATTGCGGAGCACAGTGGCGGGACGGAG
TCCTCCTTGTCTTTGCAAGAGCTGGAAACTCTGTTTTACGTTCCTGCCAGCGTCAAGGAGGGCAAAGCCAAAACCCGCCA
AGGCTGCAAGCCCATCTCCCCCGCAGCTTTGGATATCATTCTTGCGCAATATCGCAGCCAGGCCATTGCTTATTATCGCC
TGGTAGAAGAGTGCGGATTGCCCTATGAAGATGCTCGCAACATCATTGGCTACGGGATCCGACAACACTTCGTGGTCTCT
TTCAATTGCCGTAGTCTAATGCATTTTTTGGATTTACGAGCCAAAGAAGATGCTCAACGAGAAATTCAACATCTGTGTGA
ACTGATTTGGCCCCACTTTGAAGCGTGGTGTCCCCACGTGGCGGCCTGGTATCGTAAGCATCGCTGGGGAAAGGCTAGAT
TATCCCCCTAA

Upstream 100 bases:

>100_bases
GTGGAGCAGGCCAATGCCGTTGGCGTTCTCCGCTGCCAATATGATCTTAAAGGATCTCAGAATCCTAACATGCGGTGCGA
AGCACTAGGGGATGCAGCCT

Downstream 100 bases:

>100_bases
ACTTAGTTTAGATAGATATGCTCTGCTAACCCCTTCTGCGGCTAATCCTGTTTTTGATCTTTTGTTGGGTTACGGGTATG
GATCCCGAAGCTTATGAGCA

Product: thymidylate synthase, flavin-dependent

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDALFQVVVLNQTPDPERVIYQAMHQDYSPDFVTSESRIPEKYGEAVVRHLLEGNRGHYGPLEHPQITFGVGYFPHAVMQ
QARTHRVGISFDVQSFRYTGQQIADLGKKLLFASAVRSTTETAAPVGETGYGCVSDRVSGPEAYRDSGAEHIAEHSGGTE
SSLSLQELETLFYVPASVKEGKAKTRQGCKPISPAALDIILAQYRSQAIAYYRLVEECGLPYEDARNIIGYGIRQHFVVS
FNCRSLMHFLDLRAKEDAQREIQHLCELIWPHFEAWCPHVAAWYRKHRWGKARLSP

Sequences:

>Translated_296_residues
MDALFQVVVLNQTPDPERVIYQAMHQDYSPDFVTSESRIPEKYGEAVVRHLLEGNRGHYGPLEHPQITFGVGYFPHAVMQ
QARTHRVGISFDVQSFRYTGQQIADLGKKLLFASAVRSTTETAAPVGETGYGCVSDRVSGPEAYRDSGAEHIAEHSGGTE
SSLSLQELETLFYVPASVKEGKAKTRQGCKPISPAALDIILAQYRSQAIAYYRLVEECGLPYEDARNIIGYGIRQHFVVS
FNCRSLMHFLDLRAKEDAQREIQHLCELIWPHFEAWCPHVAAWYRKHRWGKARLSP
>Mature_296_residues
MDALFQVVVLNQTPDPERVIYQAMHQDYSPDFVTSESRIPEKYGEAVVRHLLEGNRGHYGPLEHPQITFGVGYFPHAVMQ
QARTHRVGISFDVQSFRYTGQQIADLGKKLLFASAVRSTTETAAPVGETGYGCVSDRVSGPEAYRDSGAEHIAEHSGGTE
SSLSLQELETLFYVPASVKEGKAKTRQGCKPISPAALDIILAQYRSQAIAYYRLVEECGLPYEDARNIIGYGIRQHFVVS
FNCRSLMHFLDLRAKEDAQREIQHLCELIWPHFEAWCPHVAAWYRKHRWGKARLSP

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 33410; Mature: 33410

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALFQVVVLNQTPDPERVIYQAMHQDYSPDFVTSESRIPEKYGEAVVRHLLEGNRGHYG
CCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
PLEHPQITFGVGYFPHAVMQQARTHRVGISFDVQSFRYTGQQIADLGKKLLFASAVRSTT
CCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETAAPVGETGYGCVSDRVSGPEAYRDSGAEHIAEHSGGTESSLSLQELETLFYVPASVKE
HHHCCCCCCCCCHHHCCCCCCHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
GKAKTRQGCKPISPAALDIILAQYRSQAIAYYRLVEECGLPYEDARNIIGYGIRQHFVVS
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHEEEE
FNCRSLMHFLDLRAKEDAQREIQHLCELIWPHFEAWCPHVAAWYRKHRWGKARLSP
ECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDALFQVVVLNQTPDPERVIYQAMHQDYSPDFVTSESRIPEKYGEAVVRHLLEGNRGHYG
CCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
PLEHPQITFGVGYFPHAVMQQARTHRVGISFDVQSFRYTGQQIADLGKKLLFASAVRSTT
CCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETAAPVGETGYGCVSDRVSGPEAYRDSGAEHIAEHSGGTESSLSLQELETLFYVPASVKE
HHHCCCCCCCCCHHHCCCCCCHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCC
GKAKTRQGCKPISPAALDIILAQYRSQAIAYYRLVEECGLPYEDARNIIGYGIRQHFVVS
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHEEEE
FNCRSLMHFLDLRAKEDAQREIQHLCELIWPHFEAWCPHVAAWYRKHRWGKARLSP
ECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11016950 [H]