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The map label for this gene is gap-2 [H]

Identifier: 86609164

GI number: 86609164

Start: 1788665

End: 1789684

Strand: Direct

Name: gap-2 [H]

Synonym: CYB_1704

Alternate gene names: 86609164

Gene position: 1788665-1789684 (Clockwise)

Preceding gene: 86609163

Following gene: 86609166

Centisome position: 58.71

GC content: 58.63

Gene sequence:

>1020_bases
GTGGTTAGGGTAGCCATCAACGGGTTTGGTCGCATTGGTCGCAACTTTTTGCGCTGTTGGCTGGGTCGCTCCCAGTCCAA
CCTGGACATTGTTGCCATCAACGACACCTCAGATGCTCGCACGGCTGCCCACCTGCTCAAGTACGATTCCATCCTTGGGC
CGTTGCAGGGAGCAGACGTTGAGCCTGCAGAAAACGGTTTGGTGGTGAACGGCAAGCATATCTATGCCGTTTCCGACCGC
AACCCCAGCAACCTGCCCTGGAAAGAGTGGAAGGTGGATCTTGTTATTGAAGCTACAGGTGTTTTTGTCGACTACCAGGG
TGCCTCTAAGCACATAGAAGCGGGGGCCAAAAAGGTGGTGATCACCGCCCCGGCCAAGGGGGGAGACATTCCCACGTTTG
TCTACGGTGTTAATCAACACACCTACGACCCGGTGCGGCACAACATTGTCAGCAACGCCAGCTGCACCACCAACTGCCTT
GCCCCGATCATCAAGGTGTTGCTGGACAAGTTCGGCGTCCTCCGTGCCACCATGACCACCACCCACAGTTACACCGGCGA
CCAGCGGATCTTAGATGGTGGTCACCGCGATCTGCGGCGGGCCCGGGCAGCAGCATTGAGCATGGTGCCCACCACCACGG
GGGCTGCCAAGGCGGTGGCTTTGGTGATCCCGGAGCTGAAAGGCAAGCTGAATGGGGTGGCGGTACGGGTTCCCACGCCC
AATGTGTCTCTGGTGGACTTGGTGGTGCAAACAGAGCGGCGCGTGATTGCCGAGGAGGTAAACGCTGCCCTGAAGGAAGC
CTCGGAAACCACGATGAAAGGGATCATCGCCTACTCGGATATTCCCTTGGTCTCCATCGACTACCGCGGCCACGACTGCT
CGGCCATTGTGGATGCGGAGATGACCAGTGTGCTGGATGGGGATCTGGTCAAGGTCATGGCTTGGTACGACAACGAGTGG
GGCTACTCCCAGCGGGTGTTGGACTTGGCGGAATACATGGCCGCTCACTGGGTGGAGTAG

Upstream 100 bases:

>100_bases
CCCTTGGATCCCAAATTTTGTCTTCAGAATGTTCAGGGGTTGCGATATCATGTGCTAGGCAGCAGCCCCCAAGAGATTTC
AAGCAGCGAGGTCAGGAGCA

Downstream 100 bases:

>100_bases
GCTGCTTCGGTTGGCAACCCTCTTCTGTTCCCCATTATTCCCCCATCGAGAACTGGGCAAAAACCTGCCAGCGCTTGCCG
TCGTGGAGGAGAAGCGTCAA

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MVRVAINGFGRIGRNFLRCWLGRSQSNLDIVAINDTSDARTAAHLLKYDSILGPLQGADVEPAENGLVVNGKHIYAVSDR
NPSNLPWKEWKVDLVIEATGVFVDYQGASKHIEAGAKKVVITAPAKGGDIPTFVYGVNQHTYDPVRHNIVSNASCTTNCL
APIIKVLLDKFGVLRATMTTTHSYTGDQRILDGGHRDLRRARAAALSMVPTTTGAAKAVALVIPELKGKLNGVAVRVPTP
NVSLVDLVVQTERRVIAEEVNAALKEASETTMKGIIAYSDIPLVSIDYRGHDCSAIVDAEMTSVLDGDLVKVMAWYDNEW
GYSQRVLDLAEYMAAHWVE

Sequences:

>Translated_339_residues
MVRVAINGFGRIGRNFLRCWLGRSQSNLDIVAINDTSDARTAAHLLKYDSILGPLQGADVEPAENGLVVNGKHIYAVSDR
NPSNLPWKEWKVDLVIEATGVFVDYQGASKHIEAGAKKVVITAPAKGGDIPTFVYGVNQHTYDPVRHNIVSNASCTTNCL
APIIKVLLDKFGVLRATMTTTHSYTGDQRILDGGHRDLRRARAAALSMVPTTTGAAKAVALVIPELKGKLNGVAVRVPTP
NVSLVDLVVQTERRVIAEEVNAALKEASETTMKGIIAYSDIPLVSIDYRGHDCSAIVDAEMTSVLDGDLVKVMAWYDNEW
GYSQRVLDLAEYMAAHWVE
>Mature_339_residues
MVRVAINGFGRIGRNFLRCWLGRSQSNLDIVAINDTSDARTAAHLLKYDSILGPLQGADVEPAENGLVVNGKHIYAVSDR
NPSNLPWKEWKVDLVIEATGVFVDYQGASKHIEAGAKKVVITAPAKGGDIPTFVYGVNQHTYDPVRHNIVSNASCTTNCL
APIIKVLLDKFGVLRATMTTTHSYTGDQRILDGGHRDLRRARAAALSMVPTTTGAAKAVALVIPELKGKLNGVAVRVPTP
NVSLVDLVVQTERRVIAEEVNAALKEASETTMKGIIAYSDIPLVSIDYRGHDCSAIVDAEMTSVLDGDLVKVMAWYDNEW
GYSQRVLDLAEYMAAHWVE

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=46.3855421686747, Blast_Score=290, Evalue=2e-78,
Organism=Homo sapiens, GI7669492, Length=337, Percent_Identity=44.8071216617211, Blast_Score=278, Evalue=4e-75,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=49.1017964071856, Blast_Score=320, Evalue=8e-89,
Organism=Escherichia coli, GI1789295, Length=337, Percent_Identity=44.213649851632, Blast_Score=274, Evalue=6e-75,
Organism=Caenorhabditis elegans, GI17534677, Length=340, Percent_Identity=44.7058823529412, Blast_Score=271, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=43.620178041543, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=43.620178041543, Blast_Score=269, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17534679, Length=340, Percent_Identity=44.1176470588235, Blast_Score=269, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=47.6190476190476, Blast_Score=306, Evalue=4e-84,
Organism=Saccharomyces cerevisiae, GI6321631, Length=338, Percent_Identity=48.5207100591716, Blast_Score=303, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6322468, Length=336, Percent_Identity=47.3214285714286, Blast_Score=299, Evalue=3e-82,
Organism=Drosophila melanogaster, GI85725000, Length=336, Percent_Identity=46.4285714285714, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI22023983, Length=336, Percent_Identity=46.4285714285714, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI17933600, Length=336, Percent_Identity=45.5357142857143, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI18110149, Length=336, Percent_Identity=45.5357142857143, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI19922412, Length=334, Percent_Identity=44.0119760479042, Blast_Score=269, Evalue=2e-72,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36878; Mature: 36878

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRVAINGFGRIGRNFLRCWLGRSQSNLDIVAINDTSDARTAAHLLKYDSILGPLQGADV
CEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCC
EPAENGLVVNGKHIYAVSDRNPSNLPWKEWKVDLVIEATGVFVDYQGASKHIEAGAKKVV
CCCCCCEEECCCEEEEECCCCCCCCCHHHEEEEEEEEEEEEEEEECCCCHHHHCCCCEEE
ITAPAKGGDIPTFVYGVNQHTYDPVRHNIVSNASCTTNCLAPIIKVLLDKFGVLRATMTT
EECCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEEEE
THSYTGDQRILDGGHRDLRRARAAALSMVPTTTGAAKAVALVIPELKGKLNGVAVRVPTP
CCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCHHHEEEEEEHHHCCCCCCEEEEECCC
NVSLVDLVVQTERRVIAEEVNAALKEASETTMKGIIAYSDIPLVSIDYRGHDCSAIVDAE
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCEEEHHH
MTSVLDGDLVKVMAWYDNEWGYSQRVLDLAEYMAAHWVE
HHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVRVAINGFGRIGRNFLRCWLGRSQSNLDIVAINDTSDARTAAHLLKYDSILGPLQGADV
CEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCC
EPAENGLVVNGKHIYAVSDRNPSNLPWKEWKVDLVIEATGVFVDYQGASKHIEAGAKKVV
CCCCCCEEECCCEEEEECCCCCCCCCHHHEEEEEEEEEEEEEEEECCCCHHHHCCCCEEE
ITAPAKGGDIPTFVYGVNQHTYDPVRHNIVSNASCTTNCLAPIIKVLLDKFGVLRATMTT
EECCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEEEE
THSYTGDQRILDGGHRDLRRARAAALSMVPTTTGAAKAVALVIPELKGKLNGVAVRVPTP
CCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCHHHEEEEEEHHHCCCCCCEEEEECCC
NVSLVDLVVQTERRVIAEEVNAALKEASETTMKGIIAYSDIPLVSIDYRGHDCSAIVDAE
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCEEEHHH
MTSVLDGDLVKVMAWYDNEWGYSQRVLDLAEYMAAHWVE
HHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]