Click here to switch to the map view.

The map label for this gene is thrS [H]

Identifier: 86608959

GI number: 86608959

Start: 1566888

End: 1568699

Strand: Reverse

Name: thrS [H]

Synonym: CYB_1492

Alternate gene names: 86608959

Gene position: 1568699-1566888 (Counterclockwise)

Preceding gene: 86608961

Following gene: 86608958

Centisome position: 51.49

GC content: 57.45

Gene sequence:

>1812_bases
ATGTCTCAGCCAGCCGAATCACCTCAGAAGGCCAACAGCACCCTCAAACTGCTGCGCACTCACGAGTCTCCCAAACTGGA
GCGCATCCGCCACACCACTTCCCATGTCCTGGCTATGGCGGTGCAAAAGCTGTTTCCCAAGGCCCAGGTGACCATCGGCC
CCACAACCGACTACGGCTTCTACTACGATTTTGACCATCCCGAGCCCTTCACGCCGGAAGATCTGGATCGCATCAAAAAA
GAGATGCAGGCAATCATCAAAAAGGGCCTGCCGGTGATCCGCGAGGAGGTGAGCCGTGAAGAGGCCAGGCGCCGCATCGA
AGCCCTCGGAGAACCCTACAAGCTGGAGATCTTAGACAGCATTCCCGAAGGGGAGGTCATCAGCATTTACCACTTGGGGA
ATGAATGGTGGGATCTCTGTGCCGGTCCCCACGTGGAAAACACCCAAGAGCTCAACCCCAAAGCTTTCGATCTGCTCAGC
GTGGCCGGCGCTTATTGGCGGGGGGATGAAACCAAGCCGCAGCTCCAACGCATCTACGGCACCGCCTGGGAAACTCCAGA
GGAGCTGAAGGAATACAAGCGGCGGCTGGAGGAGGCCAAACGGCGGGATCACCGCAAGCTGGGCAAAGAACTGGGTCTCT
TCCTGTTTTCCGATGAAGTGGGTCCGGGCTTGCCCCTTTGGACTCCGAAAGGAACTACCCTACGCTGGGTGCTGGAGGAT
TTTCTCAAGCAGGAGCAGCTCAAGCGGGGCTACCTGCCGGTGGTTACCCCTCATATTGCCCGTGTGGACTTGTTCAAGAT
CTCCGGCCACTGGCAAAAGTATCGGGAAGATATGTTTCCCATGATGGCGGAGAATGAGCAGGCGCGTGCGGCTGAACAGG
GCTTTGTCATGAAGCCGATGAACTGTCCTTTTCACATCCAAATCTATAAATCAGAGCTGAGATCCTACCGCGATTTGCCG
CTGCGCTATGCCGAGTTCGGCACCGTCTATCGCTACGAACAATCGGGGGAATTGGGGGGCTTGACCCGCGTTCGCGGCTT
TACGGTGGACGACGCCCACTTGTTCGTTCGTCCCGATCAGTTGGAAGAAGAGTTTCTCAAGGTTGTCGATCTCATTCTGG
TGGTTTTCGACAAGCTCAAACTCAAAGATTTTCGCGCCCGCCTCAGCTTCCGCGATCCCAAGTCTGACAAATATCTGGGA
TCCCCTGAGGACTGGGACAGGGCCGAGAATGCCATCCGTCGCGCTGTAGAGAAGCTCTCGATGCCTCATTTTGAAGGGAT
CGGCGAAGCAGCCTTCTATGGGCCAAAGCTGGATTTTATTTTCCGCGACGCCCTGGATCGGGAGTGGCAACTGGGCACGG
TGCAGGTGGATTACCAAAACCCACAGCGCTTTGATCTGCAATACGTAGCTGAGGACGGATCCCGGCAACGCCCGGTGATG
ATCCACCGCGCTCCCTTTGGCTCGCTGGAGCGGCTGATTGGGATCCTCATCGAAGAATACGCTGGGGATTTTCCCTTCTG
GCTGGCCCCGGAACAGGTGCGCATTTTGCCCGTTTCCGATCAGTATCTGGGCTACGCCACCCAAGTGCGGGATCAGCTGC
GAGAGCAGGGGATCCGCGTCCACATCGATGCCGACAGCGATCGTTTGCCCAAAAAAATCCGCAATGCCGAGAAGGCCCGG
ATCCCCTTCATGCTGATCGTGGGGGAACAGGAACAAGCGGCAGGAACGGTGAGCGTGCGCCAGCGCCATGGACAGGAGCT
GGGATCCCTGACGGTGGCAGACTTCCTGGATCAGGTGCAGGCGCTCAACTAG

Upstream 100 bases:

>100_bases
GGCAAACAGGGGAATTGATTAGCTGGGGATCCCTGCCGCTCTCGCCCCAGCCTAAGATAGGGACACAGTATTTGATTTGT
TTGTTTCAAAGTAGGTTCCG

Downstream 100 bases:

>100_bases
CCGGTTGCGGCAATGGAGGGCAGTGGAGTTTTCAGAACTTGAGGATCCCAGATGCCGGGGAGCTCAAGAAAGGGCCTGAA
TGTCCCTTTCTAAAGAAAAG

Product: threonyl-tRNA synthetase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MSQPAESPQKANSTLKLLRTHESPKLERIRHTTSHVLAMAVQKLFPKAQVTIGPTTDYGFYYDFDHPEPFTPEDLDRIKK
EMQAIIKKGLPVIREEVSREEARRRIEALGEPYKLEILDSIPEGEVISIYHLGNEWWDLCAGPHVENTQELNPKAFDLLS
VAGAYWRGDETKPQLQRIYGTAWETPEELKEYKRRLEEAKRRDHRKLGKELGLFLFSDEVGPGLPLWTPKGTTLRWVLED
FLKQEQLKRGYLPVVTPHIARVDLFKISGHWQKYREDMFPMMAENEQARAAEQGFVMKPMNCPFHIQIYKSELRSYRDLP
LRYAEFGTVYRYEQSGELGGLTRVRGFTVDDAHLFVRPDQLEEEFLKVVDLILVVFDKLKLKDFRARLSFRDPKSDKYLG
SPEDWDRAENAIRRAVEKLSMPHFEGIGEAAFYGPKLDFIFRDALDREWQLGTVQVDYQNPQRFDLQYVAEDGSRQRPVM
IHRAPFGSLERLIGILIEEYAGDFPFWLAPEQVRILPVSDQYLGYATQVRDQLREQGIRVHIDADSDRLPKKIRNAEKAR
IPFMLIVGEQEQAAGTVSVRQRHGQELGSLTVADFLDQVQALN

Sequences:

>Translated_603_residues
MSQPAESPQKANSTLKLLRTHESPKLERIRHTTSHVLAMAVQKLFPKAQVTIGPTTDYGFYYDFDHPEPFTPEDLDRIKK
EMQAIIKKGLPVIREEVSREEARRRIEALGEPYKLEILDSIPEGEVISIYHLGNEWWDLCAGPHVENTQELNPKAFDLLS
VAGAYWRGDETKPQLQRIYGTAWETPEELKEYKRRLEEAKRRDHRKLGKELGLFLFSDEVGPGLPLWTPKGTTLRWVLED
FLKQEQLKRGYLPVVTPHIARVDLFKISGHWQKYREDMFPMMAENEQARAAEQGFVMKPMNCPFHIQIYKSELRSYRDLP
LRYAEFGTVYRYEQSGELGGLTRVRGFTVDDAHLFVRPDQLEEEFLKVVDLILVVFDKLKLKDFRARLSFRDPKSDKYLG
SPEDWDRAENAIRRAVEKLSMPHFEGIGEAAFYGPKLDFIFRDALDREWQLGTVQVDYQNPQRFDLQYVAEDGSRQRPVM
IHRAPFGSLERLIGILIEEYAGDFPFWLAPEQVRILPVSDQYLGYATQVRDQLREQGIRVHIDADSDRLPKKIRNAEKAR
IPFMLIVGEQEQAAGTVSVRQRHGQELGSLTVADFLDQVQALN
>Mature_602_residues
SQPAESPQKANSTLKLLRTHESPKLERIRHTTSHVLAMAVQKLFPKAQVTIGPTTDYGFYYDFDHPEPFTPEDLDRIKKE
MQAIIKKGLPVIREEVSREEARRRIEALGEPYKLEILDSIPEGEVISIYHLGNEWWDLCAGPHVENTQELNPKAFDLLSV
AGAYWRGDETKPQLQRIYGTAWETPEELKEYKRRLEEAKRRDHRKLGKELGLFLFSDEVGPGLPLWTPKGTTLRWVLEDF
LKQEQLKRGYLPVVTPHIARVDLFKISGHWQKYREDMFPMMAENEQARAAEQGFVMKPMNCPFHIQIYKSELRSYRDLPL
RYAEFGTVYRYEQSGELGGLTRVRGFTVDDAHLFVRPDQLEEEFLKVVDLILVVFDKLKLKDFRARLSFRDPKSDKYLGS
PEDWDRAENAIRRAVEKLSMPHFEGIGEAAFYGPKLDFIFRDALDREWQLGTVQVDYQNPQRFDLQYVAEDGSRQRPVMI
HRAPFGSLERLIGILIEEYAGDFPFWLAPEQVRILPVSDQYLGYATQVRDQLREQGIRVHIDADSDRLPKKIRNAEKARI
PFMLIVGEQEQAAGTVSVRQRHGQELGSLTVADFLDQVQALN

Specific function: Thrs Is Also A Translational Repressor Protein, It Controls The Translation Of Its Own Gene By Binding To Its mRNA. [C]

COG id: COG0441

COG function: function code J; Threonyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI38202255, Length=598, Percent_Identity=37.6254180602007, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI38570111, Length=598, Percent_Identity=36.9565217391304, Blast_Score=394, Evalue=1e-109,
Organism=Homo sapiens, GI20070344, Length=600, Percent_Identity=38, Blast_Score=380, Evalue=1e-105,
Organism=Escherichia coli, GI1788013, Length=590, Percent_Identity=42.0338983050847, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1786392, Length=169, Percent_Identity=26.6272189349112, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71984184, Length=595, Percent_Identity=36.3025210084034, Blast_Score=403, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71984192, Length=595, Percent_Identity=36.3025210084034, Blast_Score=402, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6322112, Length=614, Percent_Identity=37.6221498371335, Blast_Score=397, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6322654, Length=401, Percent_Identity=34.1645885286783, Blast_Score=246, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24583842, Length=595, Percent_Identity=38.4873949579832, Blast_Score=428, Evalue=1e-120,
Organism=Drosophila melanogaster, GI28574141, Length=595, Percent_Identity=38.4873949579832, Blast_Score=428, Evalue=1e-120,
Organism=Drosophila melanogaster, GI24583839, Length=595, Percent_Identity=38.4873949579832, Blast_Score=428, Evalue=1e-120,

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 69942; Mature: 69810

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPAESPQKANSTLKLLRTHESPKLERIRHTTSHVLAMAVQKLFPKAQVTIGPTTDYGF
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCE
YYDFDHPEPFTPEDLDRIKKEMQAIIKKGLPVIREEVSREEARRRIEALGEPYKLEILDS
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
IPEGEVISIYHLGNEWWDLCAGPHVENTQELNPKAFDLLSVAGAYWRGDETKPQLQRIYG
CCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHC
TAWETPEELKEYKRRLEEAKRRDHRKLGKELGLFLFSDEVGPGLPLWTPKGTTLRWVLED
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHH
FLKQEQLKRGYLPVVTPHIARVDLFKISGHWQKYREDMFPMMAENEQARAAEQGFVMKPM
HHHHHHHHCCCCCCCCCCHHEEEEEEECCHHHHHHHHHCCHHCCCCHHHHHHCCCEECCC
NCPFHIQIYKSELRSYRDLPLRYAEFGTVYRYEQSGELGGLTRVRGFTVDDAHLFVRPDQ
CCCEEEEEEHHHHHHHHCCCCHHHHHCCEEEECCCCCCCCCCEECCEEECCCEEEECCHH
LEEEFLKVVDLILVVFDKLKLKDFRARLSFRDPKSDKYLGSPEDWDRAENAIRRAVEKLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
MPHFEGIGEAAFYGPKLDFIFRDALDREWQLGTVQVDYQNPQRFDLQYVAEDGSRQRPVM
CCCCCCCCCHHHCCCCHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEEEECCCCCCCCEE
IHRAPFGSLERLIGILIEEYAGDFPFWLAPEQVRILPVSDQYLGYATQVRDQLREQGIRV
EEECCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCCEE
HIDADSDRLPKKIRNAEKARIPFMLIVGEQEQAAGTVSVRQRHGQELGSLTVADFLDQVQ
EEECCCCHHHHHHCCCHHHCCCEEEEECCCHHHCCHHHHHHHHHHHHHCCHHHHHHHHHH
ALN
CCC
>Mature Secondary Structure 
SQPAESPQKANSTLKLLRTHESPKLERIRHTTSHVLAMAVQKLFPKAQVTIGPTTDYGF
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCE
YYDFDHPEPFTPEDLDRIKKEMQAIIKKGLPVIREEVSREEARRRIEALGEPYKLEILDS
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
IPEGEVISIYHLGNEWWDLCAGPHVENTQELNPKAFDLLSVAGAYWRGDETKPQLQRIYG
CCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHC
TAWETPEELKEYKRRLEEAKRRDHRKLGKELGLFLFSDEVGPGLPLWTPKGTTLRWVLED
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHH
FLKQEQLKRGYLPVVTPHIARVDLFKISGHWQKYREDMFPMMAENEQARAAEQGFVMKPM
HHHHHHHHCCCCCCCCCCHHEEEEEEECCHHHHHHHHHCCHHCCCCHHHHHHCCCEECCC
NCPFHIQIYKSELRSYRDLPLRYAEFGTVYRYEQSGELGGLTRVRGFTVDDAHLFVRPDQ
CCCEEEEEEHHHHHHHHCCCCHHHHHCCEEEECCCCCCCCCCEECCEEECCCEEEECCHH
LEEEFLKVVDLILVVFDKLKLKDFRARLSFRDPKSDKYLGSPEDWDRAENAIRRAVEKLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
MPHFEGIGEAAFYGPKLDFIFRDALDREWQLGTVQVDYQNPQRFDLQYVAEDGSRQRPVM
CCCCCCCCCHHHCCCCHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEEEECCCCCCCCEE
IHRAPFGSLERLIGILIEEYAGDFPFWLAPEQVRILPVSDQYLGYATQVRDQLREQGIRV
EEECCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCCEE
HIDADSDRLPKKIRNAEKARIPFMLIVGEQEQAAGTVSVRQRHGQELGSLTVADFLDQVQ
EEECCCCHHHHHHCCCHHHCCCEEEEECCCHHHCCHHHHHHHHHHHHHCCHHHHHHHHHH
ALN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA