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The map label for this gene is ziaR [H]

Identifier: 86608791

GI number: 86608791

Start: 1378426

End: 1378770

Strand: Reverse

Name: ziaR [H]

Synonym: CYB_1316

Alternate gene names: 86608791

Gene position: 1378770-1378426 (Counterclockwise)

Preceding gene: 86608792

Following gene: 86608790

Centisome position: 45.25

GC content: 56.23

Gene sequence:

>345_bases
ATGGTTTCGTTCCTGGTTGAGGTAGAGGGGAATTTGACAGATGAGCAGGTGCGGGAGGGATTCCACGCCCTCTCTGACCC
GATTCGCCTGCGCGTGCTGCAACTGCTGCAGGGGCGTGAGTTGTGTGTTTGTGATCTCTGCGAGGAGCTGAAGGTGAGCC
AATCCAAGCTCTCGTTTCACCTAAAAACCCTGCGGGATGCGAAATTGGTCAATGCTCGCCAGCAGGGGCGCTGGATTTAC
TACAGCCTCAACCCACCCGGTTTTCAGCTCCTGCAGCATTTTTTGGATAGATTGGGGCGAGCTGGCCCCGTCAAGGCCGC
AGTTCCCTGTGTGGAAGACCTCTAA

Upstream 100 bases:

>100_bases
CGAGTGAGATGCTGCCAAACTGGTTGATTGTCGCGCCTTTCCCCTGCCATCGAATCCATCAGCAGCCGCAGCGCAAAACT
CCTGCTACCCTGGTTGAATG

Downstream 100 bases:

>100_bases
GGCGAGCAGGGATCCCAAAATGTCCCTAGAAAAACTGTCGGATCCCGCCCTTGTACATTCCGAAGACGGGCTTGCTGCAA
CACAAGAAATTACAGATGTG

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MVSFLVEVEGNLTDEQVREGFHALSDPIRLRVLQLLQGRELCVCDLCEELKVSQSKLSFHLKTLRDAKLVNARQQGRWIY
YSLNPPGFQLLQHFLDRLGRAGPVKAAVPCVEDL

Sequences:

>Translated_114_residues
MVSFLVEVEGNLTDEQVREGFHALSDPIRLRVLQLLQGRELCVCDLCEELKVSQSKLSFHLKTLRDAKLVNARQQGRWIY
YSLNPPGFQLLQHFLDRLGRAGPVKAAVPCVEDL
>Mature_114_residues
MVSFLVEVEGNLTDEQVREGFHALSDPIRLRVLQLLQGRELCVCDLCEELKVSQSKLSFHLKTLRDAKLVNARQQGRWIY
YSLNPPGFQLLQHFLDRLGRAGPVKAAVPCVEDL

Specific function: Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ziaA-mediated efflux of excess zinc into the periplasm [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=66, Percent_Identity=48.4848484848485, Blast_Score=61, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12975; Mature: 12975

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSFLVEVEGNLTDEQVREGFHALSDPIRLRVLQLLQGRELCVCDLCEELKVSQSKLSFH
CCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LKTLRDAKLVNARQQGRWIYYSLNPPGFQLLQHFLDRLGRAGPVKAAVPCVEDL
HHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCHHCCHHCCC
>Mature Secondary Structure
MVSFLVEVEGNLTDEQVREGFHALSDPIRLRVLQLLQGRELCVCDLCEELKVSQSKLSFH
CCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LKTLRDAKLVNARQQGRWIYYSLNPPGFQLLQHFLDRLGRAGPVKAAVPCVEDL
HHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9724772 [H]