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The map label for this gene is uvrC

Identifier: 86608727

GI number: 86608727

Start: 1300591

End: 1302462

Strand: Reverse

Name: uvrC

Synonym: CYB_1251

Alternate gene names: 86608727

Gene position: 1302462-1300591 (Counterclockwise)

Preceding gene: 86608734

Following gene: 86608726

Centisome position: 42.75

GC content: 55.13

Gene sequence:

>1872_bases
ATGACCGTCCCTCTGATTCACAGCCGTGACGTTCTAGAGAGCCGTCTCAAGGAGATTCCTGCTGAACCCGGCGTATATTT
AATGCGAGATGCCACGGATCAGATCCTCTATGTAGGCAAGTCCAAGAAATTGCGCTCTCGAGTGCGATCTTATTTCCGCT
TCACCAGCGACCTGTCCCCTCGCATTCAGCGCATGGTAGCTCAGGTTTGCGAGATCGAGTTTATCGTAACCGACAATGAA
AGTGAAGCTTTAGCCCTAGAAGATAACCTGATTAAAACCCATCAGCCCCCCTACAATGTTCTTCTCAAGGATGACAAAAA
GTATCCCTATTTGTGTATTACCTGGTCGGAGCCTTATCCCCAGCTTTACATCACCCGCCATCGTCGCCTTGATCGGAATC
AAGACAAATACTATGGCCCCTACACCGATGTTGGCCTGTTGCGCCATACCCTTGGGTTGGTCAAACGAATTTTTCCCTTG
CGCCAACGGCCCAAACCTCTGTACAAAGATCGCACCTGTTTGAACTACGACATTGGGCGCTGCCCCGGGGTATGCCAAGG
CTTGATCAGCCCAGAAGAGTATCGCAAAACGCTGACTCAAGTGGCCATGATCTTCCAAGGCCAGACAGATGAGCTGATCC
GAGAGCTGCAGGAGAAGATGATCCAGGCCGCCGAACAGGAAAATTACGAGGCAGCCGCACGATATCGGGATCAAATTCGC
GGTTTGGAACAATTGGGAGAATCCCAGAAGGTCTCTTTGCCTAACTCTACCGTCAGCCGTGATGCTCTGGCCTTGGCCAT
GAATGATTCACGAGCCTGCATTCAATTGTTTCAGGTGCGGGCAGGCAAGTTGGTGGGGCGGCTGGGGTTTGTGGCCGAAA
ACCGCGGTGACGACCCAGGCCTTATCTTGCAGCGGGCTTTACAAGAGCATTATCAATACTGCGATCCGGTGGAAATTCCC
TCTGAGATTTTGACCCAGTATGAATTGCCCGATCACGATTTTCTGGAGTCTTGGCTGAGTCAGAAAAAAGGCCGCAAGGT
CAGCCTTGTTGCCCCCCAACGGCAGAGCAAAGCCGAGCTGATCGAGTTGGTTGAGCGGAATGCCCAACTGGAGCTAACCC
GCACTCAGCGCTTGGCGGATCGGGATGCCGCGGCCTTGGAGCGCTTGGCAGAAGTCTTGGATTTGCCGGATGTGCCCCGC
CGTCTAGAAGCCTACGATATTTCCCACATCCAGGGATCCGATGCTGTGGCCAGTCAGGTGGTGTTTATCGATGGCCTGCC
TGCCAAACAGCACTACCGCCGCTACAAGATTCGCAACCCTGAGGTGCGCCCCGGTCACTCCGATGATTTTGCCAGCCATG
CAGAAGTGGCCCGGCGTCGCTTCAGCAAAATGACCCCTGAGGATCAGCCGGATTTGGTGCTCATCGACGGGGGCAAGGGG
CAGTTGTCGGCAGTCATGGCCGTCTTGGCGGATTTGGGGCTGGATCACCTGCCGGTGATTGCCTTGGCCAAACGAGAAGA
AGAGATCTTTCTGCCGGGGAATCCTGTGCCCTTGCGGTTGCCGGCCCAAGATCCGGCTCGCTTGTTGTTGCAACGCCTGC
GAGATGAAGCCCACCGATTTGCTCTCGCCTTTCATCGCCAGCAACGGAAAGCGCGTCAACATGCCTCTACGCTGGACGAG
ATCCCCGGCCTGGGCAAGTATCGGCAAAAGCTGCTGATGGAAGAATTTCGGTCGATTGCCCGCATTCAGGTGGCTTCAGA
AGACCAGCTGGCCCAAGTGCCCGGCATTGGCCCGAAGATTGCCCGGCAGATTTACCGCTACTTTCACCCGGAAACTCAGG
CGGAATCCCCGGAGACAGCGCAGGTGGAGTAG

Upstream 100 bases:

>100_bases
TGTCTCCACATGGGTTGGAGTCAGTGTTGCCGAGAAAAGCCATATCCTTGCTAGATTGAAGTCATGGGATCCCTGACTCT
ACCCGGTAGAACTGAACTTT

Downstream 100 bases:

>100_bases
TTGAGAATCCGCACAGGGATCCCTGCTCCCCCAGCACTCGGTGGGGTGATATCCACAGAAGCCTGAGCACCCTTCCTCGC
CCGTGATTTTACGAGATCAC

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MTVPLIHSRDVLESRLKEIPAEPGVYLMRDATDQILYVGKSKKLRSRVRSYFRFTSDLSPRIQRMVAQVCEIEFIVTDNE
SEALALEDNLIKTHQPPYNVLLKDDKKYPYLCITWSEPYPQLYITRHRRLDRNQDKYYGPYTDVGLLRHTLGLVKRIFPL
RQRPKPLYKDRTCLNYDIGRCPGVCQGLISPEEYRKTLTQVAMIFQGQTDELIRELQEKMIQAAEQENYEAAARYRDQIR
GLEQLGESQKVSLPNSTVSRDALALAMNDSRACIQLFQVRAGKLVGRLGFVAENRGDDPGLILQRALQEHYQYCDPVEIP
SEILTQYELPDHDFLESWLSQKKGRKVSLVAPQRQSKAELIELVERNAQLELTRTQRLADRDAAALERLAEVLDLPDVPR
RLEAYDISHIQGSDAVASQVVFIDGLPAKQHYRRYKIRNPEVRPGHSDDFASHAEVARRRFSKMTPEDQPDLVLIDGGKG
QLSAVMAVLADLGLDHLPVIALAKREEEIFLPGNPVPLRLPAQDPARLLLQRLRDEAHRFALAFHRQQRKARQHASTLDE
IPGLGKYRQKLLMEEFRSIARIQVASEDQLAQVPGIGPKIARQIYRYFHPETQAESPETAQVE

Sequences:

>Translated_623_residues
MTVPLIHSRDVLESRLKEIPAEPGVYLMRDATDQILYVGKSKKLRSRVRSYFRFTSDLSPRIQRMVAQVCEIEFIVTDNE
SEALALEDNLIKTHQPPYNVLLKDDKKYPYLCITWSEPYPQLYITRHRRLDRNQDKYYGPYTDVGLLRHTLGLVKRIFPL
RQRPKPLYKDRTCLNYDIGRCPGVCQGLISPEEYRKTLTQVAMIFQGQTDELIRELQEKMIQAAEQENYEAAARYRDQIR
GLEQLGESQKVSLPNSTVSRDALALAMNDSRACIQLFQVRAGKLVGRLGFVAENRGDDPGLILQRALQEHYQYCDPVEIP
SEILTQYELPDHDFLESWLSQKKGRKVSLVAPQRQSKAELIELVERNAQLELTRTQRLADRDAAALERLAEVLDLPDVPR
RLEAYDISHIQGSDAVASQVVFIDGLPAKQHYRRYKIRNPEVRPGHSDDFASHAEVARRRFSKMTPEDQPDLVLIDGGKG
QLSAVMAVLADLGLDHLPVIALAKREEEIFLPGNPVPLRLPAQDPARLLLQRLRDEAHRFALAFHRQQRKARQHASTLDE
IPGLGKYRQKLLMEEFRSIARIQVASEDQLAQVPGIGPKIARQIYRYFHPETQAESPETAQVE
>Mature_622_residues
TVPLIHSRDVLESRLKEIPAEPGVYLMRDATDQILYVGKSKKLRSRVRSYFRFTSDLSPRIQRMVAQVCEIEFIVTDNES
EALALEDNLIKTHQPPYNVLLKDDKKYPYLCITWSEPYPQLYITRHRRLDRNQDKYYGPYTDVGLLRHTLGLVKRIFPLR
QRPKPLYKDRTCLNYDIGRCPGVCQGLISPEEYRKTLTQVAMIFQGQTDELIRELQEKMIQAAEQENYEAAARYRDQIRG
LEQLGESQKVSLPNSTVSRDALALAMNDSRACIQLFQVRAGKLVGRLGFVAENRGDDPGLILQRALQEHYQYCDPVEIPS
EILTQYELPDHDFLESWLSQKKGRKVSLVAPQRQSKAELIELVERNAQLELTRTQRLADRDAAALERLAEVLDLPDVPRR
LEAYDISHIQGSDAVASQVVFIDGLPAKQHYRRYKIRNPEVRPGHSDDFASHAEVARRRFSKMTPEDQPDLVLIDGGKGQ
LSAVMAVLADLGLDHLPVIALAKREEEIFLPGNPVPLRLPAQDPARLLLQRLRDEAHRFALAFHRQQRKARQHASTLDEI
PGLGKYRQKLLMEEFRSIARIQVASEDQLAQVPGIGPKIARQIYRYFHPETQAESPETAQVE

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain

Homologues:

Organism=Escherichia coli, GI87081999, Length=607, Percent_Identity=36.0790774299835, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1788037, Length=195, Percent_Identity=31.2820512820513, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UVRC_SYNJB (Q2JM21)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_477489.1
- ProteinModelPortal:   Q2JM21
- STRING:   Q2JM21
- GeneID:   3900985
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_1251
- TIGR:   CYB_1251
- eggNOG:   COG0322
- HOGENOM:   HBG566029
- OMA:   DVLYVGK
- PhylomeDB:   Q2JM21
- ProtClustDB:   PRK00558
- BioCyc:   SSP321332:CYB_1251-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00203
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305
- SMART:   SM00465
- SMART:   SM00278
- TIGRFAMs:   TIGR00194

Pfam domain/function: PF01541 GIY-YIG; PF00633 HHH; PF02151 UVR; PF08459 UvrC_HhH_N; SSF47781 RuvA_2_like; SSF46600 UvrB_C; SSF82771 UvrC_N

EC number: NA

Molecular weight: Translated: 71460; Mature: 71329

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS50151 UVR; PS50164 UVRC_1; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPLIHSRDVLESRLKEIPAEPGVYLMRDATDQILYVGKSKKLRSRVRSYFRFTSDLSP
CCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCH
RIQRMVAQVCEIEFIVTDNESEALALEDNLIKTHQPPYNVLLKDDKKYPYLCITWSEPYP
HHHHHHHHHHCEEEEEECCCCCEEEECCCHHHCCCCCCCEEEECCCCCCEEEEECCCCCC
QLYITRHRRLDRNQDKYYGPYTDVGLLRHTLGLVKRIFPLRQRPKPLYKDRTCLNYDIGR
CHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCC
CPGVCQGLISPEEYRKTLTQVAMIFQGQTDELIRELQEKMIQAAEQENYEAAARYRDQIR
CCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GLEQLGESQKVSLPNSTVSRDALALAMNDSRACIQLFQVRAGKLVGRLGFVAENRGDDPG
HHHHHCCCCEECCCCCHHCCHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LILQRALQEHYQYCDPVEIPSEILTQYELPDHDFLESWLSQKKGRKVSLVAPQRQSKAEL
HHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHH
IELVERNAQLELTRTQRLADRDAAALERLAEVLDLPDVPRRLEAYDISHIQGSDAVASQV
HHHHHCCCCEEEHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHEE
VFIDGLPAKQHYRRYKIRNPEVRPGHSDDFASHAEVARRRFSKMTPEDQPDLVLIDGGKG
EEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
QLSAVMAVLADLGLDHLPVIALAKREEEIFLPGNPVPLRLPAQDPARLLLQRLRDEAHRF
HHHHHHHHHHHCCCCCCCHHHEECCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHH
ALAFHRQQRKARQHASTLDEIPGLGKYRQKLLMEEFRSIARIQVASEDQLAQVPGIGPKI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHCCCCCHHH
ARQIYRYFHPETQAESPETAQVE
HHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TVPLIHSRDVLESRLKEIPAEPGVYLMRDATDQILYVGKSKKLRSRVRSYFRFTSDLSP
CCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCH
RIQRMVAQVCEIEFIVTDNESEALALEDNLIKTHQPPYNVLLKDDKKYPYLCITWSEPYP
HHHHHHHHHHCEEEEEECCCCCEEEECCCHHHCCCCCCCEEEECCCCCCEEEEECCCCCC
QLYITRHRRLDRNQDKYYGPYTDVGLLRHTLGLVKRIFPLRQRPKPLYKDRTCLNYDIGR
CHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCC
CPGVCQGLISPEEYRKTLTQVAMIFQGQTDELIRELQEKMIQAAEQENYEAAARYRDQIR
CCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GLEQLGESQKVSLPNSTVSRDALALAMNDSRACIQLFQVRAGKLVGRLGFVAENRGDDPG
HHHHHCCCCEECCCCCHHCCHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LILQRALQEHYQYCDPVEIPSEILTQYELPDHDFLESWLSQKKGRKVSLVAPQRQSKAEL
HHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHH
IELVERNAQLELTRTQRLADRDAAALERLAEVLDLPDVPRRLEAYDISHIQGSDAVASQV
HHHHHCCCCEEEHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHEE
VFIDGLPAKQHYRRYKIRNPEVRPGHSDDFASHAEVARRRFSKMTPEDQPDLVLIDGGKG
EEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
QLSAVMAVLADLGLDHLPVIALAKREEEIFLPGNPVPLRLPAQDPARLLLQRLRDEAHRF
HHHHHHHHHHHCCCCCCCHHHEECCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHH
ALAFHRQQRKARQHASTLDEIPGLGKYRQKLLMEEFRSIARIQVASEDQLAQVPGIGPKI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHCCCCCHHH
ARQIYRYFHPETQAESPETAQVE
HHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA