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The map label for this gene is yciC [H]

Identifier: 86608647

GI number: 86608647

Start: 1208687

End: 1209706

Strand: Reverse

Name: yciC [H]

Synonym: CYB_1171

Alternate gene names: 86608647

Gene position: 1209706-1208687 (Counterclockwise)

Preceding gene: 86608648

Following gene: 86608646

Centisome position: 39.71

GC content: 55.0

Gene sequence:

>1020_bases
GTGCCTAAGCGAGGCTTACCTGTCACCATCATCACAGGTTTTTTGGGCAGTGGGAAAACCACCCTTCTCAACCACATCCT
CAACAACCAGAAAGGGATGCGCACAGCGGTGCTGGTCAACGAGTTCGGCGAGATCAGCATCGATGCGGAACTGATCGTCT
CCAGCGAAGAAGACTTGGTGGAGTTGAACAACGGCTGCATTTGCTGCACCATCCGAGATGACATCGCCGAGAGTGTTTTG
CGGCTGATGGAACGCTCTGACCACATCGACTACTTGGTGGTGGAGACCACGGGATTGGCCGATCCCTTGCCGGTGGCCCT
CACCTTTTTGGGGCCAGAATTGCGAGATCTGACGCGGCTAGACTCGATTATCACCCTGGTAGATGCCACCAACTTTGCCC
CCGATCTGTTCAACAGCAACGTGGCCTACAGCCAAATTGCCTATGGGGATGTGATTCTCCTCAACAAAATCGATTTGGTC
GAGGAAGCCGAGATCGAGCGTCTGGAAAAACGCATCCGCGAGATCAAAGAAGATGCCCGCATTTTGCGCACCGTCAACAG
CGCAGTTCCCCTGGAGCTAATCTTGGATACCGATTTGTTTCAGGCCAGTTCCTTGCCCCAAGAAGAAGCCCATGATCACG
ACAGTCACGACCACCATGACCATGAGCACGATCATGACCACCACCACTCCCATCACAGCCACATCGAGGCCGACGGCTTT
AACTCCCTAGCCTTTGAGAGCGATCAGCCCTTCTCTTTGGATGCTTTCCAAAATTTTCTCAACGAGTTGCCCGATGCAGT
CTTTCGTGCCAAAGGGGTGTTGTGGTTCGAGGAAAGCCCAGAGCGACATATCTTTCACCTCAGCGGTCGGCGCTATACCC
TCAGCAGCGATGAGTGGCCTCGCCAGCCCAAAAACCAGTTGGTGCTCATCGGTCAGCGCCTCGATACAGCCCAGCTGCGG
AAAAAACTCCAAGCCTGTCTTGCCCGCCCGGCCACGCGGGGTCAAGGGTTTGGTCGCTGA

Upstream 100 bases:

>100_bases
GAGAGGTTCACCCGGCCTCAGGGGACAAGGGCAATGAGGGTAAAGTGGAAGAGTTCCCTCTATATCGGATCGCTGCCACT
CTATGACCGCAACCATCGAA

Downstream 100 bases:

>100_bases
ATCAGGACTTGGCGGCAGTCCAGGCTAAAGAAAGTCGGGCTACATTCCAGCACCCTCGATCATAAACCCCTGAGGTGATG
GCGCACCCTCCATGTCCGAC

Product: cobalamin biosynthesis protein CobW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MPKRGLPVTIITGFLGSGKTTLLNHILNNQKGMRTAVLVNEFGEISIDAELIVSSEEDLVELNNGCICCTIRDDIAESVL
RLMERSDHIDYLVVETTGLADPLPVALTFLGPELRDLTRLDSIITLVDATNFAPDLFNSNVAYSQIAYGDVILLNKIDLV
EEAEIERLEKRIREIKEDARILRTVNSAVPLELILDTDLFQASSLPQEEAHDHDSHDHHDHEHDHDHHHSHHSHIEADGF
NSLAFESDQPFSLDAFQNFLNELPDAVFRAKGVLWFEESPERHIFHLSGRRYTLSSDEWPRQPKNQLVLIGQRLDTAQLR
KKLQACLARPATRGQGFGR

Sequences:

>Translated_339_residues
MPKRGLPVTIITGFLGSGKTTLLNHILNNQKGMRTAVLVNEFGEISIDAELIVSSEEDLVELNNGCICCTIRDDIAESVL
RLMERSDHIDYLVVETTGLADPLPVALTFLGPELRDLTRLDSIITLVDATNFAPDLFNSNVAYSQIAYGDVILLNKIDLV
EEAEIERLEKRIREIKEDARILRTVNSAVPLELILDTDLFQASSLPQEEAHDHDSHDHHDHEHDHDHHHSHHSHIEADGF
NSLAFESDQPFSLDAFQNFLNELPDAVFRAKGVLWFEESPERHIFHLSGRRYTLSSDEWPRQPKNQLVLIGQRLDTAQLR
KKLQACLARPATRGQGFGR
>Mature_338_residues
PKRGLPVTIITGFLGSGKTTLLNHILNNQKGMRTAVLVNEFGEISIDAELIVSSEEDLVELNNGCICCTIRDDIAESVLR
LMERSDHIDYLVVETTGLADPLPVALTFLGPELRDLTRLDSIITLVDATNFAPDLFNSNVAYSQIAYGDVILLNKIDLVE
EAEIERLEKRIREIKEDARILRTVNSAVPLELILDTDLFQASSLPQEEAHDHDSHDHHDHEHDHDHHHSHHSHIEADGFN
SLAFESDQPFSLDAFQNFLNELPDAVFRAKGVLWFEESPERHIFHLSGRRYTLSSDEWPRQPKNQLVLIGQRLDTAQLRK
KLQACLARPATRGQGFGR

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=232, Percent_Identity=42.2413793103448, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI33469141, Length=231, Percent_Identity=41.5584415584416, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI223941779, Length=201, Percent_Identity=44.2786069651741, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI148727351, Length=350, Percent_Identity=35.1428571428571, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI146231952, Length=232, Percent_Identity=40.948275862069, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI223941776, Length=234, Percent_Identity=39.7435897435897, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI119120938, Length=130, Percent_Identity=46.1538461538462, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI87082430, Length=329, Percent_Identity=33.434650455927, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1788499, Length=281, Percent_Identity=28.4697508896797, Blast_Score=89, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324356, Length=220, Percent_Identity=34.0909090909091, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 38296; Mature: 38164

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKRGLPVTIITGFLGSGKTTLLNHILNNQKGMRTAVLVNEFGEISIDAELIVSSEEDLV
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEECCEEEECCCHHHH
ELNNGCICCTIRDDIAESVLRLMERSDHIDYLVVETTGLADPLPVALTFLGPELRDLTRL
HHCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCHHHHHHHH
DSIITLVDATNFAPDLFNSNVAYSQIAYGDVILLNKIDLVEEAEIERLEKRIREIKEDAR
HHHHHHHHCCCCCHHHHCCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
ILRTVNSAVPLELILDTDLFQASSLPQEEAHDHDSHDHHDHEHDHDHHHSHHSHIEADGF
HHHHHHCCCCEEEEECCCHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSLAFESDQPFSLDAFQNFLNELPDAVFRAKGVLWFEESPERHIFHLSGRRYTLSSDEWP
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCEEECCCCCCC
RQPKNQLVLIGQRLDTAQLRKKLQACLARPATRGQGFGR
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PKRGLPVTIITGFLGSGKTTLLNHILNNQKGMRTAVLVNEFGEISIDAELIVSSEEDLV
CCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEECCEEEECCCHHHH
ELNNGCICCTIRDDIAESVLRLMERSDHIDYLVVETTGLADPLPVALTFLGPELRDLTRL
HHCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCHHHHHHHH
DSIITLVDATNFAPDLFNSNVAYSQIAYGDVILLNKIDLVEEAEIERLEKRIREIKEDAR
HHHHHHHHCCCCCHHHHCCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
ILRTVNSAVPLELILDTDLFQASSLPQEEAHDHDSHDHHDHEHDHDHHHSHHSHIEADGF
HHHHHHCCCCEEEEECCCHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSLAFESDQPFSLDAFQNFLNELPDAVFRAKGVLWFEESPERHIFHLSGRRYTLSSDEWP
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCEEECCCCCCC
RQPKNQLVLIGQRLDTAQLRKKLQACLARPATRGQGFGR
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]