Click here to switch to the map view.

The map label for this gene is tadA [H]

Identifier: 86608124

GI number: 86608124

Start: 646125

End: 646640

Strand: Reverse

Name: tadA [H]

Synonym: CYB_0635

Alternate gene names: 86608124

Gene position: 646640-646125 (Counterclockwise)

Preceding gene: 86608131

Following gene: 86608123

Centisome position: 21.22

GC content: 65.89

Gene sequence:

>516_bases
ATGCTCCATTCCTCCGAGCCGCAAGGGTGGGATCTGTGGCAGCGCCACCGCGCCTGGATGCAGTTGGCCTTGCGAGAAGC
TGAGCAAGCGGGAGAAGCCGGAGAGGTTCCGGTGGCCGCTCTGGTGGTGGGGCCAGGGGAAAAGTTGCTGGCTTTGAGCA
GCAACCGGCGGGAACGGGATCGGGATCCCACGGCCCATGCGGAGATTCTGGCCCTACGGCAGGCAGGGCAGCGCTTGGGC
GATTGGCAGCTGCAGGGCTGTCGGCTGTATGTGACCCTGGAGCCCTGCCCCATGTGTGCGGGGGCAATCAGCCAATCGCG
GCTGGCCCAGGTAATCTACGGCGCCGATGATCCCAAGGCCGGAGCACTGCGCAGCGTGCTCAATTTGCCAGCTTCTGCCG
CCAGCTTCCATTGCCCGGAGGTCATCGGCGGAGTCTGCGAGGCCGAGTGTCGCCGCCTATTGCAGCAGTGGTTTTGCCGC
CGGCGCGGGATCCCCTCTGAGCCGGCTGAATCCTGA

Upstream 100 bases:

>100_bases
ACTCTTTACTTTTGGATGTTCGGGGTATGTGTGCTTACCCTAGCAAATCTTGCGGACAGAGGCAGTGCTCGAAACGCCCA
AAATGATCGGGGATCCGAGT

Downstream 100 bases:

>100_bases
CCGAGGGACTGGGGGCGGAAAATTCTGGGTTGAAGTCGTGCATCTGCAGGATGTTTTTGATACTGTCATAACGGGTTCGG
CTGGCCCTTGCCCGGGATCC

Product: cytidine and deoxycytidylate deaminase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MLHSSEPQGWDLWQRHRAWMQLALREAEQAGEAGEVPVAALVVGPGEKLLALSSNRRERDRDPTAHAEILALRQAGQRLG
DWQLQGCRLYVTLEPCPMCAGAISQSRLAQVIYGADDPKAGALRSVLNLPASAASFHCPEVIGGVCEAECRRLLQQWFCR
RRGIPSEPAES

Sequences:

>Translated_171_residues
MLHSSEPQGWDLWQRHRAWMQLALREAEQAGEAGEVPVAALVVGPGEKLLALSSNRRERDRDPTAHAEILALRQAGQRLG
DWQLQGCRLYVTLEPCPMCAGAISQSRLAQVIYGADDPKAGALRSVLNLPASAASFHCPEVIGGVCEAECRRLLQQWFCR
RRGIPSEPAES
>Mature_171_residues
MLHSSEPQGWDLWQRHRAWMQLALREAEQAGEAGEVPVAALVVGPGEKLLALSSNRRERDRDPTAHAEILALRQAGQRLG
DWQLQGCRLYVTLEPCPMCAGAISQSRLAQVIYGADDPKAGALRSVLNLPASAASFHCPEVIGGVCEAECRRLLQQWFCR
RRGIPSEPAES

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=152, Percent_Identity=32.2368421052632, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI145693172, Length=147, Percent_Identity=42.1768707482993, Blast_Score=111, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17554608, Length=98, Percent_Identity=39.7959183673469, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17541138, Length=119, Percent_Identity=34.453781512605, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555996, Length=102, Percent_Identity=37.2549019607843, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322425, Length=163, Percent_Identity=29.4478527607362, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355527, Length=155, Percent_Identity=31.6129032258064, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 18793; Mature: 18793

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHSSEPQGWDLWQRHRAWMQLALREAEQAGEAGEVPVAALVVGPGEKLLALSSNRRERD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCCCCCCC
RDPTAHAEILALRQAGQRLGDWQLQGCRLYVTLEPCPMCAGAISQSRLAQVIYGADDPKA
CCCHHHHHHHHHHHHHHHCCCCEECCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCH
GALRSVLNLPASAASFHCPEVIGGVCEAECRRLLQQWFCRRRGIPSEPAES
HHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLHSSEPQGWDLWQRHRAWMQLALREAEQAGEAGEVPVAALVVGPGEKLLALSSNRRERD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCCCCCCC
RDPTAHAEILALRQAGQRLGDWQLQGCRLYVTLEPCPMCAGAISQSRLAQVIYGADDPKA
CCCHHHHHHHHHHHHHHHCCCCEECCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCH
GALRSVLNLPASAASFHCPEVIGGVCEAECRRLLQQWFCRRRGIPSEPAES
HHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]