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The map label for this gene is cvrA [H]

Identifier: 86607818

GI number: 86607818

Start: 334259

End: 336613

Strand: Direct

Name: cvrA [H]

Synonym: CYB_0320

Alternate gene names: 86607818

Gene position: 334259-336613 (Clockwise)

Preceding gene: 86607817

Following gene: 86607824

Centisome position: 10.97

GC content: 60.13

Gene sequence:

>2355_bases
ATGCAAGATTCATTTGAGCTGACGATCCTGTTTACGCTAGCCCTGGTGGCTGGGATCGCTGCTCAGGTGCTGGCCAATTT
TGTCAAAGTGCCCAGCATTGTATTCCTGCTGCTGTTTGGCCTGTTGCTGGGACCAGATGGTTTGGGCTGGGTTCATCCCC
AAGTCATGGGATCCGGGCTGGAAGCGCTGGTGTCGTTGGCGGTGGCTCTGATCTTGTTTGAGGGGGGACTGAACCTGCGG
CTGCAACGTCTCAATCCGGTATCCGATAGCCTGCGCAATTTGGTTTTGTTGGGATCCCTGCTGACCCTGGTGGGGGGAGC
GGCAGCAGCTCACTATCTGGGGGAGTTTCCCTGGCGGCTGGCTTTTTTGTTTGGATCCCTGGTGGTGGTGACGGGGCCGA
CGGTGATCAACCCTATCCTGAAGCGGGTACGAGTCGATTCGGCAGTCAGCACCCTCCTGGAAGGAGAAGGGGTGCTCATC
GATCCCATCGGGGCCATTTTGGCGGTGGTGGTGCTGCAGGTGGTGCTCTCTGGCCATCCCAGTTTTCTCATGGCCTTGGA
ACAGTTGTCCAGCCGTCTGGCCATCGGGTCGGCGGTGGGAGCGCTGGGGGGCTGGCTGATGGGATCCTTCCTGCTTTGGT
CGCGGCAGTTTTTAACCGAGGAGCTGCGCAACTCGGTGGTGATGGCGGGGGCCCTGGGGGTGTTTGCCTTGGCCCAGTCG
CTGCGATCGGAGGCGGGGCTGATGGCAGTGGTGATGGCGGGCCTGGTGGTGCGGCAGAAGGCGGCCATTGCCGAGCGGGG
TGTGCGGCAGTTTCACGGCCAGTTGGTGGTGTTGGCCATCTCGGTGATCTTTATTTTGCTTACCGCCACGCTCTCCCTCA
AGGCGGTGTTTGCCCTGGGCTGGGGATCCCTGGCCACAGTGCTGTGTTTGATGCTGGTCATCCGTCCCTTGAGTGTGTGG
CTGTGTACCTGGCGCAGCGACCTGAATTGGCGGCAGAAGCTGTTTGTGGCTTGGCTGGCTCCTCGGGGCATTGTGGCGGC
TTCGGTGGCCTCCTTGTTTGCCATTCTGCTGACAGAACGGGGCATTACCGGGGGAGATGCCCTCAAGGCGCTGGTGTTTT
TGACCATCTCGGTGACGGTGACGGTACAGGGGCTGACCGCGGCTTGGGTGGCCCGTTGGCTGGGTCTGGATCAGGGCAGT
TCCACCATAATCATCGGCGATCATCCCCTCACCAACCAATTGGCCCAGTTGATGCGCTCGCTCAACCAGACGGTCGAGGT
GATCCCGTTGGTTTCTGGGTCTTCCAAAAATGGGCACGGCAGCTACAAAGCTCCCCACCCAACAGACGGTAAGGACTCCA
TCCCGCCATCCCGTAAGTCCTCCACATCCCTGTCAGGAACGCCGAAGCGTCGTCCAGCAGATGGCTTGCCCCCACAACTT
CATTCCTCTGACGGCAACGGCACCCACAAGTCTGCCCCAAGCCAGGAAGTCGGCAAGCCAGAAGCCATCCCCGGATCCCT
GCAGGAAGCTGTACTGAACGAGTCTGCTTTGTTGAAGGCCGATATCGACCATGCGGAAACTCTGTTGATCCTGACTCTGG
ATCCGCAGGTGAACTGGGCCATTGCCGAGTTGATGGTGAAACTCTCGGTTTCGGCCACCATCTGGACGGTGTTGCTGCCG
GATATGCCCATCTCAGAAGGGATCCGCACCTTGCAGCCTTCCTTCCCCCAACTGCAGCGCTGGGCCGGCTATCTGGAGGC
CAATCGGGCCGAGCTGCGCTCGATCACCCTACCCACGTTGGCAGACCTGGGCCTGCCTCTCCCTTTATCGCTACGTGACG
CTTCTGCGAATGCGGCCTCAACCCTGCCGGAGGCAGTGCGGAGCAATAGAGCTGATGTCTTGACGGCTCAAGAGTCGTTC
CCGACAGCGGTGCGGAGCGCTTTTTCAGCACCAGCGCTGCCCAATCCCTTCCTGGCCCAGATGGGACTGGAGGATCCCAC
CCTTGAACGGCTGCGGGATCAGTTTGCCTATCGAATCAAAGCCGATCTATGCCTGCCCTTGTTGTTGGTGCGCCCGCAGC
GGCTGAGGAGCGGCTCATCTCGACCGGGTCGGCTCTTCTACCTGCCTGAGCCAGACATTTGGCGACGCGGGGATCGCATC
TACTACCTGGAGCGCGTTTCCAGCCCTGTGGATGCTGGTGTTCTCTCCGCCAAAGAGCCTGATTCCCAAGAATGGGATCC
GTCCGCAGCCGTTCACACTCGCGTTCGCGACAGTGGTGCGGAGCACAACAGTGGGATAGAGTCTTTGTTGCCGCCCCAGT
ATGTTGAGGGCGTCAAGCTCCACTTTGATCTCTAA

Upstream 100 bases:

>100_bases
AACGATGGAAACAAAACGATGGAAACAATGAGAGGGTTGGCGTTCAGTAGCTGGAAAGGTAAGGGCTCCGTCCCGCTATT
GCGTTCGGTTAAGCCTCAAT

Downstream 100 bases:

>100_bases
CCAGCCAGCGGCCACTGGGGATGAGCGAGCACCCTTGCACCTGCTCAGGCCGACCCAGATAAACCCAAGCAAAGGTGCCG
CTATCCAGTTGCACCCACTG

Product: monovalent cation:proton antiporter-2 (CPA2) family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 784; Mature: 784

Protein sequence:

>784_residues
MQDSFELTILFTLALVAGIAAQVLANFVKVPSIVFLLLFGLLLGPDGLGWVHPQVMGSGLEALVSLAVALILFEGGLNLR
LQRLNPVSDSLRNLVLLGSLLTLVGGAAAAHYLGEFPWRLAFLFGSLVVVTGPTVINPILKRVRVDSAVSTLLEGEGVLI
DPIGAILAVVVLQVVLSGHPSFLMALEQLSSRLAIGSAVGALGGWLMGSFLLWSRQFLTEELRNSVVMAGALGVFALAQS
LRSEAGLMAVVMAGLVVRQKAAIAERGVRQFHGQLVVLAISVIFILLTATLSLKAVFALGWGSLATVLCLMLVIRPLSVW
LCTWRSDLNWRQKLFVAWLAPRGIVAASVASLFAILLTERGITGGDALKALVFLTISVTVTVQGLTAAWVARWLGLDQGS
STIIIGDHPLTNQLAQLMRSLNQTVEVIPLVSGSSKNGHGSYKAPHPTDGKDSIPPSRKSSTSLSGTPKRRPADGLPPQL
HSSDGNGTHKSAPSQEVGKPEAIPGSLQEAVLNESALLKADIDHAETLLILTLDPQVNWAIAELMVKLSVSATIWTVLLP
DMPISEGIRTLQPSFPQLQRWAGYLEANRAELRSITLPTLADLGLPLPLSLRDASANAASTLPEAVRSNRADVLTAQESF
PTAVRSAFSAPALPNPFLAQMGLEDPTLERLRDQFAYRIKADLCLPLLLVRPQRLRSGSSRPGRLFYLPEPDIWRRGDRI
YYLERVSSPVDAGVLSAKEPDSQEWDPSAAVHTRVRDSGAEHNSGIESLLPPQYVEGVKLHFDL

Sequences:

>Translated_784_residues
MQDSFELTILFTLALVAGIAAQVLANFVKVPSIVFLLLFGLLLGPDGLGWVHPQVMGSGLEALVSLAVALILFEGGLNLR
LQRLNPVSDSLRNLVLLGSLLTLVGGAAAAHYLGEFPWRLAFLFGSLVVVTGPTVINPILKRVRVDSAVSTLLEGEGVLI
DPIGAILAVVVLQVVLSGHPSFLMALEQLSSRLAIGSAVGALGGWLMGSFLLWSRQFLTEELRNSVVMAGALGVFALAQS
LRSEAGLMAVVMAGLVVRQKAAIAERGVRQFHGQLVVLAISVIFILLTATLSLKAVFALGWGSLATVLCLMLVIRPLSVW
LCTWRSDLNWRQKLFVAWLAPRGIVAASVASLFAILLTERGITGGDALKALVFLTISVTVTVQGLTAAWVARWLGLDQGS
STIIIGDHPLTNQLAQLMRSLNQTVEVIPLVSGSSKNGHGSYKAPHPTDGKDSIPPSRKSSTSLSGTPKRRPADGLPPQL
HSSDGNGTHKSAPSQEVGKPEAIPGSLQEAVLNESALLKADIDHAETLLILTLDPQVNWAIAELMVKLSVSATIWTVLLP
DMPISEGIRTLQPSFPQLQRWAGYLEANRAELRSITLPTLADLGLPLPLSLRDASANAASTLPEAVRSNRADVLTAQESF
PTAVRSAFSAPALPNPFLAQMGLEDPTLERLRDQFAYRIKADLCLPLLLVRPQRLRSGSSRPGRLFYLPEPDIWRRGDRI
YYLERVSSPVDAGVLSAKEPDSQEWDPSAAVHTRVRDSGAEHNSGIESLLPPQYVEGVKLHFDL
>Mature_784_residues
MQDSFELTILFTLALVAGIAAQVLANFVKVPSIVFLLLFGLLLGPDGLGWVHPQVMGSGLEALVSLAVALILFEGGLNLR
LQRLNPVSDSLRNLVLLGSLLTLVGGAAAAHYLGEFPWRLAFLFGSLVVVTGPTVINPILKRVRVDSAVSTLLEGEGVLI
DPIGAILAVVVLQVVLSGHPSFLMALEQLSSRLAIGSAVGALGGWLMGSFLLWSRQFLTEELRNSVVMAGALGVFALAQS
LRSEAGLMAVVMAGLVVRQKAAIAERGVRQFHGQLVVLAISVIFILLTATLSLKAVFALGWGSLATVLCLMLVIRPLSVW
LCTWRSDLNWRQKLFVAWLAPRGIVAASVASLFAILLTERGITGGDALKALVFLTISVTVTVQGLTAAWVARWLGLDQGS
STIIIGDHPLTNQLAQLMRSLNQTVEVIPLVSGSSKNGHGSYKAPHPTDGKDSIPPSRKSSTSLSGTPKRRPADGLPPQL
HSSDGNGTHKSAPSQEVGKPEAIPGSLQEAVLNESALLKADIDHAETLLILTLDPQVNWAIAELMVKLSVSATIWTVLLP
DMPISEGIRTLQPSFPQLQRWAGYLEANRAELRSITLPTLADLGLPLPLSLRDASANAASTLPEAVRSNRADVLTAQESF
PTAVRSAFSAPALPNPFLAQMGLEDPTLERLRDQFAYRIKADLCLPLLLVRPQRLRSGSSRPGRLFYLPEPDIWRRGDRI
YYLERVSSPVDAGVLSAKEPDSQEWDPSAAVHTRVRDSGAEHNSGIESLLPPQYVEGVKLHFDL

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018421
- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 84116; Mature: 84116

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDSFELTILFTLALVAGIAAQVLANFVKVPSIVFLLLFGLLLGPDGLGWVHPQVMGSGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
EALVSLAVALILFEGGLNLRLQRLNPVSDSLRNLVLLGSLLTLVGGAAAAHYLGEFPWRL
HHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AFLFGSLVVVTGPTVINPILKRVRVDSAVSTLLEGEGVLIDPIGAILAVVVLQVVLSGHP
HHHHHCHHEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCC
SFLMALEQLSSRLAIGSAVGALGGWLMGSFLLWSRQFLTEELRNSVVMAGALGVFALAQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHH
LRSEAGLMAVVMAGLVVRQKAAIAERGVRQFHGQLVVLAISVIFILLTATLSLKAVFALG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WGSLATVLCLMLVIRPLSVWLCTWRSDLNWRQKLFVAWLAPRGIVAASVASLFAILLTER
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
GITGGDALKALVFLTISVTVTVQGLTAAWVARWLGLDQGSSTIIIGDHPLTNQLAQLMRS
CCCCHHHHHHHHHHHEEEEEEECHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHH
LNQTVEVIPLVSGSSKNGHGSYKAPHPTDGKDSIPPSRKSSTSLSGTPKRRPADGLPPQL
HCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HSSDGNGTHKSAPSQEVGKPEAIPGSLQEAVLNESALLKADIDHAETLLILTLDPQVNWA
CCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHCCHHHEEECCCCCCEEEEEEECCCCHHH
IAELMVKLSVSATIWTVLLPDMPISEGIRTLQPSFPQLQRWAGYLEANRAELRSITLPTL
HHHHHHHHHHHHHEEEHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHCCCHHH
ADLGLPLPLSLRDASANAASTLPEAVRSNRADVLTAQESFPTAVRSAFSAPALPNPFLAQ
HHCCCCCCCEECCCCCCHHHHHHHHHHCCCCCEEECHHHCCHHHHHHHCCCCCCCHHHHH
MGLEDPTLERLRDQFAYRIKADLCLPLLLVRPQRLRSGSSRPGRLFYLPEPDIWRRGDRI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEECCCCHHHHCCCEE
YYLERVSSPVDAGVLSAKEPDSQEWDPSAAVHTRVRDSGAEHNSGIESLLPPQYVEGVKL
EEHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHCCCHHHHCCEEE
HFDL
EECC
>Mature Secondary Structure
MQDSFELTILFTLALVAGIAAQVLANFVKVPSIVFLLLFGLLLGPDGLGWVHPQVMGSGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
EALVSLAVALILFEGGLNLRLQRLNPVSDSLRNLVLLGSLLTLVGGAAAAHYLGEFPWRL
HHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AFLFGSLVVVTGPTVINPILKRVRVDSAVSTLLEGEGVLIDPIGAILAVVVLQVVLSGHP
HHHHHCHHEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCC
SFLMALEQLSSRLAIGSAVGALGGWLMGSFLLWSRQFLTEELRNSVVMAGALGVFALAQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHH
LRSEAGLMAVVMAGLVVRQKAAIAERGVRQFHGQLVVLAISVIFILLTATLSLKAVFALG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WGSLATVLCLMLVIRPLSVWLCTWRSDLNWRQKLFVAWLAPRGIVAASVASLFAILLTER
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
GITGGDALKALVFLTISVTVTVQGLTAAWVARWLGLDQGSSTIIIGDHPLTNQLAQLMRS
CCCCHHHHHHHHHHHEEEEEEECHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHH
LNQTVEVIPLVSGSSKNGHGSYKAPHPTDGKDSIPPSRKSSTSLSGTPKRRPADGLPPQL
HCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HSSDGNGTHKSAPSQEVGKPEAIPGSLQEAVLNESALLKADIDHAETLLILTLDPQVNWA
CCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHCCHHHEEECCCCCCEEEEEEECCCCHHH
IAELMVKLSVSATIWTVLLPDMPISEGIRTLQPSFPQLQRWAGYLEANRAELRSITLPTL
HHHHHHHHHHHHHEEEHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHCCCHHH
ADLGLPLPLSLRDASANAASTLPEAVRSNRADVLTAQESFPTAVRSAFSAPALPNPFLAQ
HHCCCCCCCEECCCCCCHHHHHHHHHHCCCCCEEECHHHCCHHHHHHHCCCCCCCHHHHH
MGLEDPTLERLRDQFAYRIKADLCLPLLLVRPQRLRSGSSRPGRLFYLPEPDIWRRGDRI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEECCCCHHHHCCCEE
YYLERVSSPVDAGVLSAKEPDSQEWDPSAAVHTRVRDSGAEHNSGIESLLPPQYVEGVKL
EEHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHCCCHHHHCCEEE
HFDL
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA