Click here to switch to the map view.

The map label for this gene is cobN [H]

Identifier: 86607803

GI number: 86607803

Start: 317061

End: 319277

Strand: Reverse

Name: cobN [H]

Synonym: CYB_0304

Alternate gene names: 86607803

Gene position: 319277-317061 (Counterclockwise)

Preceding gene: 86607804

Following gene: 86607802

Centisome position: 10.48

GC content: 61.84

Gene sequence:

>2217_bases
ATGCACCGAATAGCTGCTTTGCCAGGGGGATGGGATCCTTCCCAATCCGGCGTCATTTTCTTGGAGCAGGATCCCGCTCC
CATCGTTATCCTTTCGGCAGCCGATACGGATCTCACGGCCTTGAGCGCAGCCCTGCGCCTGTTGCCCGGCGATTTTCCGG
CGGTGCGGGCGGCCAATTTGTTGCAGTTGCAACAGCCCCTAAGCCTGGATGACTATGCCGAGAGGGTGCTGCGGCGGGCG
CAGGTGGTGCTCCTTCGCCTGTTGGGGGGAAGGGCCTACTGGAGCTATGGCCTGGAGGTAGCCAAGCAGGTGGCCGCCGA
GGAGGGATCCACCCTGATCGTCATTCCTGGGGACGATCGCCCCGACTGGGATTTGGTGAGCCATTCCACTGTGCCCCTGG
CGGTGGCGGATCGGGTGTGGCGGTACTGGCTGGAGGGGGGAGCGGAGAATGTGGCTGCCTGTCTGCTGTTGCTGGCTAGG
GAGTTCCTAGGGGGCCAATATTCGGCGCCGGATCCACAAGGGTTGCCTCGTCTTGGGATCTACCAACCTCCCGTAGCCTC
GCCGACGGATCCCCAAGCTCCCAAGGTGGGGATTTTGCTCTACCGAGCCCATGTTCTGGCGGGGAACATAGAGCCGGTGG
ATCAATTGGCAAAAGCCTTGGTGGAGCGGGGGCTGCAGCCTCTGTGCCTTTACACCTACAGCCTTCAAGATCCCGACTTG
CCCCAGGCCATTCGGGATCACTTTGGCAGCCAGATTGACCTGTTGCTCAACACCACCAGTTTTTCGCTGGCGCGGTTGGA
CAGCCACCAGCCCGATGTAAGCCTGTGGCAGGAATTGGATGTGCCCGTTTTGCAGGTAATCCTTAGCAGCGGATCCCGCC
AGAGCTGGGAGGACTCCACGCGAGGACTGGGAGCGCGGGATCTGGCCATGAATGTGGCTTTGCCGGAGGTGGATGGGCGC
ATCATCAGCCGCGCCGTTTCCTTCAAGGCGGTTCAACAGCGGGATCCCCACTTGCAAACGGAGGTGGTGGCCTATGCGGC
TGTGCCGGATCGGGTGGAGTTTGTAGCCGATTTGGCGGCCAACTGGGTGAAACTGCGGCGCACCCCTGCCAACCAGCGCC
GTCTGGCTCTGATTTTGGCCAACTACCCCAGCCGGGACGGGCGGCTGGCCAATGGGGTAGGGTTGGATACACCGGCAAGC
TGCGTGGAGATTCTCAAGGTCCTGGCGGAATCCAGCTACCGGGTGGGGCCCCTGCCGCAGACAGGAGATGAGCTCATCCG
CTGGCTCACCCAGGGCCAAACCTATGACCCGCTGGGATCCCTGCGCCCCGCTCGCCAATGGCTTTCTGCTGCCCTTTATC
GAGAGTGGTTTGCCCGCTTGCCTGAGCCCATCCAGACCGACCTCGTCCGGCAGTGGGGGGATCCGCCCTCTCGAGATATT
CCCGTGGTGGGACTGCAGTTAGGGCAGGTGTTTGTAGGCATTCAGCCCCCGCGAGGCTATGACCGGGATCCGTCCTTGAA
CTACCACGCCCCGGATCTGGTGCCCCCCCACGAGTACCTGGCTTTTTACCTGTGGCTGCGGCAGGTCTTCGCCGTTCAAG
CGGTGGTGCATGTGGGCAAGCACGGCAACCTGGAATGGCTGCCCGGCAAGGGATCCGCCCTTTCCGCCACCTGCTACCCG
GAGATGGCCCTGGGGCCGCTGCCCCACTTCTACCCCTTCATTGTCAACGATCCGGGAGAGGGATCCCAGGCCAAGCGGCG
AGCCCAGGCAGTGATTATCGACCACCTCACCCCGCCCCTTACTCGTGCTGAGCTGTACGGCCCCCTGGCGGACTTGGAAC
GGTTGATGGATGAGTACGTGCAGGCCCAACAGTTGGATCCCAGTCGTTGTCCCCTGATTCGCGCCCAGATTCAGGAGCTG
GTTCGAGCCGAGCATCTAGACCAGCAGTTCAACTTGGAAAAAGAAGAAGATTGGAATCGCCTGGATGGCTATCTCTGCGA
GCTAAAAGAATCTCAGATTCGCGATGGGCTGCACATCTTTGGTCGAATCCCTGCCGGTGAGCAGCTTGTTGATCTGGTGG
TAGCCCTGGCCCGCTACCCTGGCCACGGGCAACTGGGGATTACTCAGGCCATTGCCCGCGATTGGGGATGGGACTGGGAT
CCCTTGACCGCCGACCTGACAGATCCTTGGCCAGAGGGATCCCCGAACTCGCCGTAA

Upstream 100 bases:

>100_bases
CGGGAGCCCTTCCTGACCAGTTGAGCGCTGGGAGCTGGGGTGCTTCTGTGCTTCAAGTACAGTCGCTAAGCCTGAGCTTC
CTTCCCTTGGGAGAGCGGCC

Downstream 100 bases:

>100_bases
CCCAAGCCAAGCGTTTTATTTTCCTCTCTCAGGGAGCAAGGAAGAATCTTAAGAGTAAGTTGATCGGGATCCCTCATCAA
CTCCTCTGTTGGAACAATGG

Product: CobN/magnesium chelatase domain-containing protein

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobN [H]

Number of amino acids: Translated: 738; Mature: 738

Protein sequence:

>738_residues
MHRIAALPGGWDPSQSGVIFLEQDPAPIVILSAADTDLTALSAALRLLPGDFPAVRAANLLQLQQPLSLDDYAERVLRRA
QVVLLRLLGGRAYWSYGLEVAKQVAAEEGSTLIVIPGDDRPDWDLVSHSTVPLAVADRVWRYWLEGGAENVAACLLLLAR
EFLGGQYSAPDPQGLPRLGIYQPPVASPTDPQAPKVGILLYRAHVLAGNIEPVDQLAKALVERGLQPLCLYTYSLQDPDL
PQAIRDHFGSQIDLLLNTTSFSLARLDSHQPDVSLWQELDVPVLQVILSSGSRQSWEDSTRGLGARDLAMNVALPEVDGR
IISRAVSFKAVQQRDPHLQTEVVAYAAVPDRVEFVADLAANWVKLRRTPANQRRLALILANYPSRDGRLANGVGLDTPAS
CVEILKVLAESSYRVGPLPQTGDELIRWLTQGQTYDPLGSLRPARQWLSAALYREWFARLPEPIQTDLVRQWGDPPSRDI
PVVGLQLGQVFVGIQPPRGYDRDPSLNYHAPDLVPPHEYLAFYLWLRQVFAVQAVVHVGKHGNLEWLPGKGSALSATCYP
EMALGPLPHFYPFIVNDPGEGSQAKRRAQAVIIDHLTPPLTRAELYGPLADLERLMDEYVQAQQLDPSRCPLIRAQIQEL
VRAEHLDQQFNLEKEEDWNRLDGYLCELKESQIRDGLHIFGRIPAGEQLVDLVVALARYPGHGQLGITQAIARDWGWDWD
PLTADLTDPWPEGSPNSP

Sequences:

>Translated_738_residues
MHRIAALPGGWDPSQSGVIFLEQDPAPIVILSAADTDLTALSAALRLLPGDFPAVRAANLLQLQQPLSLDDYAERVLRRA
QVVLLRLLGGRAYWSYGLEVAKQVAAEEGSTLIVIPGDDRPDWDLVSHSTVPLAVADRVWRYWLEGGAENVAACLLLLAR
EFLGGQYSAPDPQGLPRLGIYQPPVASPTDPQAPKVGILLYRAHVLAGNIEPVDQLAKALVERGLQPLCLYTYSLQDPDL
PQAIRDHFGSQIDLLLNTTSFSLARLDSHQPDVSLWQELDVPVLQVILSSGSRQSWEDSTRGLGARDLAMNVALPEVDGR
IISRAVSFKAVQQRDPHLQTEVVAYAAVPDRVEFVADLAANWVKLRRTPANQRRLALILANYPSRDGRLANGVGLDTPAS
CVEILKVLAESSYRVGPLPQTGDELIRWLTQGQTYDPLGSLRPARQWLSAALYREWFARLPEPIQTDLVRQWGDPPSRDI
PVVGLQLGQVFVGIQPPRGYDRDPSLNYHAPDLVPPHEYLAFYLWLRQVFAVQAVVHVGKHGNLEWLPGKGSALSATCYP
EMALGPLPHFYPFIVNDPGEGSQAKRRAQAVIIDHLTPPLTRAELYGPLADLERLMDEYVQAQQLDPSRCPLIRAQIQEL
VRAEHLDQQFNLEKEEDWNRLDGYLCELKESQIRDGLHIFGRIPAGEQLVDLVVALARYPGHGQLGITQAIARDWGWDWD
PLTADLTDPWPEGSPNSP
>Mature_738_residues
MHRIAALPGGWDPSQSGVIFLEQDPAPIVILSAADTDLTALSAALRLLPGDFPAVRAANLLQLQQPLSLDDYAERVLRRA
QVVLLRLLGGRAYWSYGLEVAKQVAAEEGSTLIVIPGDDRPDWDLVSHSTVPLAVADRVWRYWLEGGAENVAACLLLLAR
EFLGGQYSAPDPQGLPRLGIYQPPVASPTDPQAPKVGILLYRAHVLAGNIEPVDQLAKALVERGLQPLCLYTYSLQDPDL
PQAIRDHFGSQIDLLLNTTSFSLARLDSHQPDVSLWQELDVPVLQVILSSGSRQSWEDSTRGLGARDLAMNVALPEVDGR
IISRAVSFKAVQQRDPHLQTEVVAYAAVPDRVEFVADLAANWVKLRRTPANQRRLALILANYPSRDGRLANGVGLDTPAS
CVEILKVLAESSYRVGPLPQTGDELIRWLTQGQTYDPLGSLRPARQWLSAALYREWFARLPEPIQTDLVRQWGDPPSRDI
PVVGLQLGQVFVGIQPPRGYDRDPSLNYHAPDLVPPHEYLAFYLWLRQVFAVQAVVHVGKHGNLEWLPGKGSALSATCYP
EMALGPLPHFYPFIVNDPGEGSQAKRRAQAVIIDHLTPPLTRAELYGPLADLERLMDEYVQAQQLDPSRCPLIRAQIQEL
VRAEHLDQQFNLEKEEDWNRLDGYLCELKESQIRDGLHIFGRIPAGEQLVDLVVALARYPGHGQLGITQAIARDWGWDWD
PLTADLTDPWPEGSPNSP

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG1429

COG function: function code H; Cobalamin biosynthesis protein CobN and related Mg-chelatases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobN family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011953
- InterPro:   IPR003672 [H]

Pfam domain/function: PF02514 CobN-Mg_chel [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 81760; Mature: 81760

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRIAALPGGWDPSQSGVIFLEQDPAPIVILSAADTDLTALSAALRLLPGDFPAVRAANL
CCCEECCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHH
LQLQQPLSLDDYAERVLRRAQVVLLRLLGGRAYWSYGLEVAKQVAAEEGSTLIVIPGDDR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
PDWDLVSHSTVPLAVADRVWRYWLEGGAENVAACLLLLAREFLGGQYSAPDPQGLPRLGI
CCCCHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
YQPPVASPTDPQAPKVGILLYRAHVLAGNIEPVDQLAKALVERGLQPLCLYTYSLQDPDL
CCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCC
PQAIRDHFGSQIDLLLNTTSFSLARLDSHQPDVSLWQELDVPVLQVILSSGSRQSWEDST
HHHHHHHCCCEEEEEEECCCHHHHHCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCHHH
RGLGARDLAMNVALPEVDGRIISRAVSFKAVQQRDPHLQTEVVAYAAVPDRVEFVADLAA
CCCCHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHEEEECCCHHHHHHHHHHH
NWVKLRRTPANQRRLALILANYPSRDGRLANGVGLDTPASCVEILKVLAESSYRVGPLPQ
HHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
TGDELIRWLTQGQTYDPLGSLRPARQWLSAALYREWFARLPEPIQTDLVRQWGDPPSRDI
CHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
PVVGLQLGQVFVGIQPPRGYDRDPSLNYHAPDLVPPHEYLAFYLWLRQVFAVQAVVHVGK
CEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
HGNLEWLPGKGSALSATCYPEMALGPLPHFYPFIVNDPGEGSQAKRRAQAVIIDHLTPPL
CCCEEEECCCCCEEEEECCCCHHCCCCCCCCCEEECCCCCCHHHHHHHHHHEECCCCCCH
TRAELYGPLADLERLMDEYVQAQQLDPSRCPLIRAQIQELVRAEHLDQQFNLEKEEDWNR
HHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LDGYLCELKESQIRDGLHIFGRIPAGEQLVDLVVALARYPGHGQLGITQAIARDWGWDWD
HHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
PLTADLTDPWPEGSPNSP
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHRIAALPGGWDPSQSGVIFLEQDPAPIVILSAADTDLTALSAALRLLPGDFPAVRAANL
CCCEECCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHH
LQLQQPLSLDDYAERVLRRAQVVLLRLLGGRAYWSYGLEVAKQVAAEEGSTLIVIPGDDR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
PDWDLVSHSTVPLAVADRVWRYWLEGGAENVAACLLLLAREFLGGQYSAPDPQGLPRLGI
CCCCHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
YQPPVASPTDPQAPKVGILLYRAHVLAGNIEPVDQLAKALVERGLQPLCLYTYSLQDPDL
CCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCC
PQAIRDHFGSQIDLLLNTTSFSLARLDSHQPDVSLWQELDVPVLQVILSSGSRQSWEDST
HHHHHHHCCCEEEEEEECCCHHHHHCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCHHH
RGLGARDLAMNVALPEVDGRIISRAVSFKAVQQRDPHLQTEVVAYAAVPDRVEFVADLAA
CCCCHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHEEEECCCHHHHHHHHHHH
NWVKLRRTPANQRRLALILANYPSRDGRLANGVGLDTPASCVEILKVLAESSYRVGPLPQ
HHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
TGDELIRWLTQGQTYDPLGSLRPARQWLSAALYREWFARLPEPIQTDLVRQWGDPPSRDI
CHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
PVVGLQLGQVFVGIQPPRGYDRDPSLNYHAPDLVPPHEYLAFYLWLRQVFAVQAVVHVGK
CEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
HGNLEWLPGKGSALSATCYPEMALGPLPHFYPFIVNDPGEGSQAKRRAQAVIIDHLTPPL
CCCEEEECCCCCEEEEECCCCHHCCCCCCCCCEEECCCCCCHHHHHHHHHHEECCCCCCH
TRAELYGPLADLERLMDEYVQAQQLDPSRCPLIRAQIQELVRAEHLDQQFNLEKEEDWNR
HHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LDGYLCELKESQIRDGLHIFGRIPAGEQLVDLVVALARYPGHGQLGITQAIARDWGWDWD
HHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
PLTADLTDPWPEGSPNSP
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]