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The map label for this gene is cobH-1 [H]

Identifier: 86607724

GI number: 86607724

Start: 234765

End: 235391

Strand: Direct

Name: cobH-1 [H]

Synonym: CYB_0225

Alternate gene names: 86607724

Gene position: 234765-235391 (Clockwise)

Preceding gene: 86607721

Following gene: 86607725

Centisome position: 7.71

GC content: 60.93

Gene sequence:

>627_bases
ATGAATGAAGCCTTCCAGGTAGACCCAATCACTGCTGCCAGCTTCCGCCAGATCGATCAAGAGATTGGCCCCCACCCCTG
GCAAGGGATCCCTTATGAGGTGGTGCGCCGCGCCATTCATGCCACTGCCGACTTTGAGCTACGGGATCGCTTTTTCTTCG
GCCCCAACGCCGTCGAACAAGCCCTGGCAGCCCTGCGGCAAAAGCGGCCTGTCGTTGTCGATGTCAGGATGGTGGCAGCT
GGGATCCAGTCAGGTCTGAAAGCCCAAGGGATCCCCCTCTACTGTGCTTTGGACTGGGTGGAGGAGCCCCGTTGGCCCGG
TCAAACCCGCGCCGCCAATGGGATGGTGAACTTGGCACGCCGCTATCCAGAAGCCCTGTTTGTCGTTGGCAATGCCCCCA
CCGCGTTGCTGGCTTTGGTGGAGGAGATTCGGGCACAGCGGGTCAAGCCGGCTTTGGTGATCGGAGTGCCGGTGGGATTT
GTGGCGGTGGAAGAGGCCAAGCAGGCGTTGGCGCAAACGGATGTTCCCCAGATTCGGGTGGAGGGCCGCAAAGGCGGATC
CCCAGTTGCTGCTGCCATTGTCAATGCCCTTCTCTTGGCAGCTCAACGGGATCCCATCCCCAACTGA

Upstream 100 bases:

>100_bases
AGACCAATCTTAGTGGTTTTCTCGGCTCGCCCAAAGCTACTTTGCTACCGGTTCTTCTTTAGGACATGCCAGCATGACTG
TGCCCCTGACTCCAGACCCA

Downstream 100 bases:

>100_bases
CTAGAATTGAAGGGATATCTTCAGACCTTTCCCATGACCCCAGAACAAGAGGAGTGGCTGATTCGCAACCTTCAGCAACA
ACAAGAACAAATCCAAGAAA

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MNEAFQVDPITAASFRQIDQEIGPHPWQGIPYEVVRRAIHATADFELRDRFFFGPNAVEQALAALRQKRPVVVDVRMVAA
GIQSGLKAQGIPLYCALDWVEEPRWPGQTRAANGMVNLARRYPEALFVVGNAPTALLALVEEIRAQRVKPALVIGVPVGF
VAVEEAKQALAQTDVPQIRVEGRKGGSPVAAAIVNALLLAAQRDPIPN

Sequences:

>Translated_208_residues
MNEAFQVDPITAASFRQIDQEIGPHPWQGIPYEVVRRAIHATADFELRDRFFFGPNAVEQALAALRQKRPVVVDVRMVAA
GIQSGLKAQGIPLYCALDWVEEPRWPGQTRAANGMVNLARRYPEALFVVGNAPTALLALVEEIRAQRVKPALVIGVPVGF
VAVEEAKQALAQTDVPQIRVEGRKGGSPVAAAIVNALLLAAQRDPIPN
>Mature_208_residues
MNEAFQVDPITAASFRQIDQEIGPHPWQGIPYEVVRRAIHATADFELRDRFFFGPNAVEQALAALRQKRPVVVDVRMVAA
GIQSGLKAQGIPLYCALDWVEEPRWPGQTRAANGMVNLARRYPEALFVVGNAPTALLALVEEIRAQRVKPALVIGVPVGF
VAVEEAKQALAQTDVPQIRVEGRKGGSPVAAAIVNALLLAAQRDPIPN

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 22612; Mature: 22612

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEAFQVDPITAASFRQIDQEIGPHPWQGIPYEVVRRAIHATADFELRDRFFFGPNAVEQ
CCCCEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHCEEEECCHHHHH
ALAALRQKRPVVVDVRMVAAGIQSGLKAQGIPLYCALDWVEEPRWPGQTRAANGMVNLAR
HHHHHHHCCCEEEEHHHHHHHHHCCCCCCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHHH
RYPEALFVVGNAPTALLALVEEIRAQRVKPALVIGVPVGFVAVEEAKQALAQTDVPQIRV
HCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEE
EGRKGGSPVAAAIVNALLLAAQRDPIPN
CCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNEAFQVDPITAASFRQIDQEIGPHPWQGIPYEVVRRAIHATADFELRDRFFFGPNAVEQ
CCCCEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHCEEEECCHHHHH
ALAALRQKRPVVVDVRMVAAGIQSGLKAQGIPLYCALDWVEEPRWPGQTRAANGMVNLAR
HHHHHHHCCCEEEEHHHHHHHHHCCCCCCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHHH
RYPEALFVVGNAPTALLALVEEIRAQRVKPALVIGVPVGFVAVEEAKQALAQTDVPQIRV
HCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEE
EGRKGGSPVAAAIVNALLLAAQRDPIPN
CCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]