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The map label for this gene is ahpC [C]

Identifier: 86607615

GI number: 86607615

Start: 127262

End: 127912

Strand: Direct

Name: ahpC [C]

Synonym: CYB_0113

Alternate gene names: 86607615

Gene position: 127262-127912 (Clockwise)

Preceding gene: 86607614

Following gene: 86607618

Centisome position: 4.18

GC content: 54.84

Gene sequence:

>651_bases
ATGTCTCTCCGACTTGGCGATACTGCTCCCAATTTCACGCAAAAGTCTACCCACGGCGAAATCGATTTCTACTCTTGGGC
CGGGGATAGCTGGGTGGTGTTGTTCTCTCACCCCGCCGACTACACGCCGGTCTGCACCACAGAGCTGGGCACCGTTGCCA
AGCTGATGCCCGAATTTGAAAAGCGGGGTGTGAAGGTGATCGCCCTCAGTGTGGACGATGTGGACTCCCACGTCGGCTGG
GTAAAAGACATCGAGGAAACCCAGAACGCCACTTTGACCTATCCCATTTTGGCAGATGCAGACCGCAAGGTCTCTCAGCT
CTACGGCATGTTGGATCAAACCAACCTCAATCAAGAAGGGCTGCCCCTGACGGTGCGCTCGGTGTTCGTTATTGATCCCA
ATAAGAAGATCCGCCTCATTCTCACCTACCCAGCCAGCACGGGCCGCAACTTCGACGAGCTCCTACGGGTGATCGATGCC
CTACAGCTGACGGATAAGTACAATGTCGTCACCCCTGCCGACTGGAAAGACGGTGACGATGTCATCATTCCGCCTTCGCT
GAAAGATCCGGAAGTGCTGAAAGAGAAGTTCCCAAAAGGCTACAAGGAAATTAAGCCCTATTTGCGGGTCGCCCCTCAGC
CCAACAAGTAG

Upstream 100 bases:

>100_bases
GAAAATCGGGGTTTATGTGGCAAGATCAAGAGGGATCGGGTCGAAGGATCCGGATCCCTGTCTCACCGGATTGAACCCTT
TTACGGAGGATCAAGAGCGT

Downstream 100 bases:

>100_bases
AAGTCTCAGCAATCGAACCTACTTTCGGCTGATCCCTTCTCTGCCGAAGCTGCGCTCCCCTCGATTTGGATCCCCGACCA
GGGGATCCTTTTTTATTTCA

Product: anti-oxidant AhpCTSA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSLRLGDTAPNFTQKSTHGEIDFYSWAGDSWVVLFSHPADYTPVCTTELGTVAKLMPEFEKRGVKVIALSVDDVDSHVGW
VKDIEETQNATLTYPILADADRKVSQLYGMLDQTNLNQEGLPLTVRSVFVIDPNKKIRLILTYPASTGRNFDELLRVIDA
LQLTDKYNVVTPADWKDGDDVIIPPSLKDPEVLKEKFPKGYKEIKPYLRVAPQPNK

Sequences:

>Translated_216_residues
MSLRLGDTAPNFTQKSTHGEIDFYSWAGDSWVVLFSHPADYTPVCTTELGTVAKLMPEFEKRGVKVIALSVDDVDSHVGW
VKDIEETQNATLTYPILADADRKVSQLYGMLDQTNLNQEGLPLTVRSVFVIDPNKKIRLILTYPASTGRNFDELLRVIDA
LQLTDKYNVVTPADWKDGDDVIIPPSLKDPEVLKEKFPKGYKEIKPYLRVAPQPNK
>Mature_215_residues
SLRLGDTAPNFTQKSTHGEIDFYSWAGDSWVVLFSHPADYTPVCTTELGTVAKLMPEFEKRGVKVIALSVDDVDSHVGWV
KDIEETQNATLTYPILADADRKVSQLYGMLDQTNLNQEGLPLTVRSVFVIDPNKKIRLILTYPASTGRNFDELLRVIDAL
QLTDKYNVVTPADWKDGDDVIIPPSLKDPEVLKEKFPKGYKEIKPYLRVAPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=222, Percent_Identity=52.7027027027027, Blast_Score=229, Evalue=1e-60,
Organism=Homo sapiens, GI32189392, Length=186, Percent_Identity=34.9462365591398, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI4505591, Length=199, Percent_Identity=32.6633165829146, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI32455266, Length=199, Percent_Identity=32.6633165829146, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI32455264, Length=199, Percent_Identity=32.6633165829146, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI5453549, Length=155, Percent_Identity=32.9032258064516, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI5802974, Length=170, Percent_Identity=32.9411764705882, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI32483377, Length=170, Percent_Identity=32.9411764705882, Blast_Score=91, Evalue=9e-19,
Organism=Escherichia coli, GI1786822, Length=155, Percent_Identity=34.1935483870968, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25153706, Length=222, Percent_Identity=42.3423423423423, Blast_Score=185, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI193204376, Length=196, Percent_Identity=33.6734693877551, Blast_Score=106, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI32565831, Length=196, Percent_Identity=33.6734693877551, Blast_Score=106, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17554494, Length=155, Percent_Identity=34.8387096774194, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319407, Length=211, Percent_Identity=58.2938388625592, Blast_Score=234, Evalue=7e-63,
Organism=Saccharomyces cerevisiae, GI6323613, Length=189, Percent_Identity=32.2751322751323, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320661, Length=171, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=54.7945205479452, Blast_Score=248, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24652436, Length=206, Percent_Identity=50.9708737864078, Blast_Score=206, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24652434, Length=206, Percent_Identity=50.4854368932039, Blast_Score=205, Evalue=2e-53,
Organism=Drosophila melanogaster, GI17975518, Length=206, Percent_Identity=50.4854368932039, Blast_Score=204, Evalue=3e-53,
Organism=Drosophila melanogaster, GI17157991, Length=168, Percent_Identity=35.1190476190476, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24641739, Length=168, Percent_Identity=35.1190476190476, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI21357347, Length=197, Percent_Identity=31.4720812182741, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17738015, Length=204, Percent_Identity=32.3529411764706, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24656348, Length=170, Percent_Identity=34.1176470588235, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI17864676, Length=170, Percent_Identity=34.1176470588235, Blast_Score=94, Evalue=7e-20,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24294; Mature: 24163

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRLGDTAPNFTQKSTHGEIDFYSWAGDSWVVLFSHPADYTPVCTTELGTVAKLMPEFE
CCEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
KRGVKVIALSVDDVDSHVGWVKDIEETQNATLTYPILADADRKVSQLYGMLDQTNLNQEG
HCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
LPLTVRSVFVIDPNKKIRLILTYPASTGRNFDELLRVIDALQLTDKYNVVTPADWKDGDD
CCEEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCC
VIIPPSLKDPEVLKEKFPKGYKEIKPYLRVAPQPNK
EEECCCCCCHHHHHHHCCCCHHHHCHHEECCCCCCC
>Mature Secondary Structure 
SLRLGDTAPNFTQKSTHGEIDFYSWAGDSWVVLFSHPADYTPVCTTELGTVAKLMPEFE
CEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
KRGVKVIALSVDDVDSHVGWVKDIEETQNATLTYPILADADRKVSQLYGMLDQTNLNQEG
HCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
LPLTVRSVFVIDPNKKIRLILTYPASTGRNFDELLRVIDALQLTDKYNVVTPADWKDGDD
CCEEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCC
VIIPPSLKDPEVLKEKFPKGYKEIKPYLRVAPQPNK
EEECCCCCCHHHHHHHCCCCHHHHCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]