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The map label for this gene is yfhR [C]

Identifier: 86607614

GI number: 86607614

Start: 126236

End: 127117

Strand: Direct

Name: yfhR [C]

Synonym: CYB_0112

Alternate gene names: 86607614

Gene position: 126236-127117 (Clockwise)

Preceding gene: 86607613

Following gene: 86607615

Centisome position: 4.14

GC content: 57.71

Gene sequence:

>882_bases
ATGACCGTATTTGTCGATGCCTTCTCGTCAATGCCAATCCGAGACCTCTTGCAATTTCCAGTTTTGGGATCCTTCTCGTG
GCTGCGCGTGGGGCGATCTTTGCTGCTCGTCGGGCTGGTGGTGTACGGCTACCTGCTCTGGCTGGGCTGGTTTCAATCGG
AGCGAATGATCTTTTTGCCTCGTCCCGCCAGCTATCGAGATGGGGACGCCATTCTCAAGCTCACGACCTCTGATGGGCTG
CAGATTTCAGCGGTATATCTGCCCAATCCGGCTGCTGCTTATACCCTCCTCTATAGCCATGGCAACGCTGAAGACTTGGG
GGATATCCTGCCCCGCTTGGTGCACCTGCAGCAGGCTGGGTTTGCCGTCTTGGCCTACGACTACCGCGGTTACGGCACCA
GCGAAGGGATCCCTTCCGAGGCCGGCGCTTACAAAGATATCGAGGCCGCTTACACTTACCTAGTTGCCCAAGGGATCCTG
CCGGAGCAGATTTTGGTTTATGGGCGCTCGGTGGGGGGTGGGCCATCGGTTTATTTGGCAGCCCAAAAGCCGGTGGGGGG
CGTGATCCTGGAATCCACCTTCGTCACAGCCTTTCGCGTCTTAACCCGCATCCCGCTGCTGCCCTTCGATCGCTTCGATA
ACCTCAGCCGCATGGCCAAGATCAATTGCCCGCTGCTGATTTTGCACGGTACCCAGGATCGTCTAATCCCCTTCTGGCAT
GCTGAAGCCCTTTATCAAGCAGCACGGGATCCCAAACGCTTGGTGCCCATCGAGGGAGCCGATCACAACAACTTGCTGCA
GGTGGCCGGAGAGCGCTATGTCCCCATCCTGCACCAATTCGTAGCCGAGCTGGTGGATCCCCATGTCGTCTTCCCTCAGT
AG

Upstream 100 bases:

>100_bases
GAGAAAAGCCTTTGGTCGCATGTATTATTGCTCCGCAATGCTGACACGAGGACGCGACCAACGTTTTGGGTGTGAGCGCA
TTGTCCTGGTTTGAATTGAA

Downstream 100 bases:

>100_bases
CGGCTTAGGTGAGGACAATCTTAAAATCACCTGTAATCCGCTCGGAAAATCGGGGTTTATGTGGCAAGATCAAGAGGGAT
CGGGTCGAAGGATCCGGATC

Product: phospholipase/carboxylesterase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTVFVDAFSSMPIRDLLQFPVLGSFSWLRVGRSLLLVGLVVYGYLLWLGWFQSERMIFLPRPASYRDGDAILKLTTSDGL
QISAVYLPNPAAAYTLLYSHGNAEDLGDILPRLVHLQQAGFAVLAYDYRGYGTSEGIPSEAGAYKDIEAAYTYLVAQGIL
PEQILVYGRSVGGGPSVYLAAQKPVGGVILESTFVTAFRVLTRIPLLPFDRFDNLSRMAKINCPLLILHGTQDRLIPFWH
AEALYQAARDPKRLVPIEGADHNNLLQVAGERYVPILHQFVAELVDPHVVFPQ

Sequences:

>Translated_293_residues
MTVFVDAFSSMPIRDLLQFPVLGSFSWLRVGRSLLLVGLVVYGYLLWLGWFQSERMIFLPRPASYRDGDAILKLTTSDGL
QISAVYLPNPAAAYTLLYSHGNAEDLGDILPRLVHLQQAGFAVLAYDYRGYGTSEGIPSEAGAYKDIEAAYTYLVAQGIL
PEQILVYGRSVGGGPSVYLAAQKPVGGVILESTFVTAFRVLTRIPLLPFDRFDNLSRMAKINCPLLILHGTQDRLIPFWH
AEALYQAARDPKRLVPIEGADHNNLLQVAGERYVPILHQFVAELVDPHVVFPQ
>Mature_292_residues
TVFVDAFSSMPIRDLLQFPVLGSFSWLRVGRSLLLVGLVVYGYLLWLGWFQSERMIFLPRPASYRDGDAILKLTTSDGLQ
ISAVYLPNPAAAYTLLYSHGNAEDLGDILPRLVHLQQAGFAVLAYDYRGYGTSEGIPSEAGAYKDIEAAYTYLVAQGILP
EQILVYGRSVGGGPSVYLAAQKPVGGVILESTFVTAFRVLTRIPLLPFDRFDNLSRMAKINCPLLILHGTQDRLIPFWHA
EALYQAARDPKRLVPIEGADHNNLLQVAGERYVPILHQFVAELVDPHVVFPQ

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI71051600, Length=233, Percent_Identity=40.7725321888412, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI71051602, Length=231, Percent_Identity=40.6926406926407, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI194306564, Length=224, Percent_Identity=37.0535714285714, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI151301175, Length=200, Percent_Identity=39.5, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI194306562, Length=222, Percent_Identity=36.9369369369369, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI49355781, Length=255, Percent_Identity=29.4117647058824, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI32451492, Length=185, Percent_Identity=31.8918918918919, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI32528310, Length=185, Percent_Identity=31.8918918918919, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI24308097, Length=181, Percent_Identity=32.5966850828729, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI109689718, Length=181, Percent_Identity=32.5966850828729, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI226510965, Length=250, Percent_Identity=28.4, Blast_Score=104, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71988362, Length=184, Percent_Identity=37.5, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71985392, Length=221, Percent_Identity=30.7692307692308, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71997133, Length=230, Percent_Identity=30.4347826086957, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17532877, Length=195, Percent_Identity=31.7948717948718, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71985387, Length=217, Percent_Identity=30.8755760368664, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17566318, Length=190, Percent_Identity=29.4736842105263, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI25143554, Length=158, Percent_Identity=31.6455696202532, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324009, Length=226, Percent_Identity=31.4159292035398, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281362521, Length=197, Percent_Identity=41.6243654822335, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI281362519, Length=197, Percent_Identity=41.6243654822335, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI28571878, Length=197, Percent_Identity=41.6243654822335, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI17137566, Length=248, Percent_Identity=30.6451612903226, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 32492; Mature: 32361

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVFVDAFSSMPIRDLLQFPVLGSFSWLRVGRSLLLVGLVVYGYLLWLGWFQSERMIFLP
CEEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
RPASYRDGDAILKLTTSDGLQISAVYLPNPAAAYTLLYSHGNAEDLGDILPRLVHLQQAG
CCCCCCCCCEEEEEECCCCEEEEEEECCCCHHEEEEEEECCCHHHHHHHHHHHHHHHHCC
FAVLAYDYRGYGTSEGIPSEAGAYKDIEAAYTYLVAQGILPEQILVYGRSVGGGPSVYLA
EEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEE
AQKPVGGVILESTFVTAFRVLTRIPLLPFDRFDNLSRMAKINCPLLILHGTQDRLIPFWH
ECCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHCCCCCEEEEECCCCCCEEHHH
AEALYQAARDPKRLVPIEGADHNNLLQVAGERYVPILHQFVAELVDPHVVFPQ
HHHHHHHHCCCCCEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TVFVDAFSSMPIRDLLQFPVLGSFSWLRVGRSLLLVGLVVYGYLLWLGWFQSERMIFLP
EEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
RPASYRDGDAILKLTTSDGLQISAVYLPNPAAAYTLLYSHGNAEDLGDILPRLVHLQQAG
CCCCCCCCCEEEEEECCCCEEEEEEECCCCHHEEEEEEECCCHHHHHHHHHHHHHHHHCC
FAVLAYDYRGYGTSEGIPSEAGAYKDIEAAYTYLVAQGILPEQILVYGRSVGGGPSVYLA
EEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEE
AQKPVGGVILESTFVTAFRVLTRIPLLPFDRFDNLSRMAKINCPLLILHGTQDRLIPFWH
ECCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHCCCCCEEEEECCCCCCEEHHH
AEALYQAARDPKRLVPIEGADHNNLLQVAGERYVPILHQFVAELVDPHVVFPQ
HHHHHHHHCCCCCEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]