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The map label for this gene is dnaA [H]

Identifier: 86607504

GI number: 86607504

Start: 64

End: 1467

Strand: Direct

Name: dnaA [H]

Synonym: CYB_0001

Alternate gene names: 86607504

Gene position: 64-1467 (Clockwise)

Preceding gene: NA

Following gene: 86607505

Centisome position: 0.0

GC content: 56.62

Gene sequence:

>1404_bases
GTGGATATTTCCCTGGATCAGCTCTGGGATGAAGCCCTGTGTCATCTGCAGGTGCAGCTCAGCCGCCCAACCTTTGAGGC
TTGGATCAAAACGGCGCGGGCTGAATCGTTGGTGGACAACCGCCTCACCATCTGTACCCCCAGCGAATGGGCGCGGGGCT
GGCTGCAAAAGCACTACGCCTCCACCATCACCGAGGTGGTGCAGCGGGTAGCCGGGATCCCTTTGCAGGTGGAGTTTTCC
GTTTCCCCCCACGCTTCTGTCGAGGCAGAACCCCCTTCAAGGGCGATTTCCCCAACATCGGGCAGAGCCGGCAGCTTACC
TGCCTCCACCACCCTAGGACTGGAAGTCGGCGGCAGCCTGCCCATGCGGGCGCCGGATCTCAACCCCAAGTATTCCTTCT
CGCGGTTTGTGGTTGGCCCCAACAACCGCATGGCTCACGCTGCAGCTCTGGCTGTGGCCGACAAGCCTGGGCGCGCCTAC
AACCCCCTGTTTCTCTGCGGTGGGGTGGGTCTAGGCAAAACCCACCTGATGCAGGCCATTGGCCACTACCAGCTAGAGGC
AAATCCACAGGCCAAAGTCTTTTACGTGTCCACCGAACGGTTTACCAACGATTTAATCGATGCCATCCGGCGAGACAGCA
TGCAGTCTTTCCGGGAGCACTATCGGGATGTGGATATTTTATTGGTGGATGACGTTCAATTTATCGAAGGCAAAGAGTAC
ACCCAAGAGGAGTTTTTTCACACCTTTAATACGCTGCACGAGTCCGGCAAGCAGATTGTGCTGGCCGCCGACCGATCTCC
TCATCTGATCCCGCGTCTGCAGGAGCGGCTTTGTTCTCGTTTCTCCATGGGTTTGATTGCGGAAATTCAATCGCCGGATA
TCGAAACCCGCATGGCCATTCTCAAGAAGAAAGCCGAGTATGAGGGAATGAACTTGCCCGCCGACGTGATCGAGTACATT
GCCACCACCTACACCAGCAACATCCGCGAGCTGGAAGGTGCCCTGATCCGCGCCGTCGCCTATGTTTCCATTTCTGGCTT
GCCGATGAGCGTGGAGACGATTCAGCCCATCCTCAATCCCCCCAGCGAGCCGAAAGAGATCACCGCCGACATGATTACCG
ATGTGGTCTGTGAAGAATTCGGCATCGACCGAGACAGTTTACTGGGATCCTCCCGCAAGCGCGACATCAGCCAAGCACGG
CAAATTGCCATGTTCTTGATGCGCCACTACACCAACCTCAGCCTGCCCAAAATTGGCGACTACTTTGGGGGAAAAGATCA
CACCACCGTCCTCTATAGCTGTGAAAAGGTCAGTCAGCTACAGCGGCAAAGTCTGCAATTTGAACGGCAACTGCAAAAAT
TGGTCGAGCGCTTGCGGGTGGTTGCCAACAGCCGGAGCAGCTAG

Upstream 100 bases:

>100_bases
ACCCCGCGCCGAGCAGTTAAATTGGGAATCCCGAAGCTCCTGTCGAGGAAGCCGCCGCTGTTTCCTCTGGGCTTCTGCTG
TGTCGCTCTGAGTGTGTGGT

Downstream 100 bases:

>100_bases
GCTTTCTGTTGTCGCTGGGCCGTCTTTGAGGTGTTGTTGCCGCGCTGTGGAGCACCTCCAGCCTTGCCCGTCTGCGTGGA
GAATCCCTCGGAAAGCGGCT

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MDISLDQLWDEALCHLQVQLSRPTFEAWIKTARAESLVDNRLTICTPSEWARGWLQKHYASTITEVVQRVAGIPLQVEFS
VSPHASVEAEPPSRAISPTSGRAGSLPASTTLGLEVGGSLPMRAPDLNPKYSFSRFVVGPNNRMAHAAALAVADKPGRAY
NPLFLCGGVGLGKTHLMQAIGHYQLEANPQAKVFYVSTERFTNDLIDAIRRDSMQSFREHYRDVDILLVDDVQFIEGKEY
TQEEFFHTFNTLHESGKQIVLAADRSPHLIPRLQERLCSRFSMGLIAEIQSPDIETRMAILKKKAEYEGMNLPADVIEYI
ATTYTSNIRELEGALIRAVAYVSISGLPMSVETIQPILNPPSEPKEITADMITDVVCEEFGIDRDSLLGSSRKRDISQAR
QIAMFLMRHYTNLSLPKIGDYFGGKDHTTVLYSCEKVSQLQRQSLQFERQLQKLVERLRVVANSRSS

Sequences:

>Translated_467_residues
MDISLDQLWDEALCHLQVQLSRPTFEAWIKTARAESLVDNRLTICTPSEWARGWLQKHYASTITEVVQRVAGIPLQVEFS
VSPHASVEAEPPSRAISPTSGRAGSLPASTTLGLEVGGSLPMRAPDLNPKYSFSRFVVGPNNRMAHAAALAVADKPGRAY
NPLFLCGGVGLGKTHLMQAIGHYQLEANPQAKVFYVSTERFTNDLIDAIRRDSMQSFREHYRDVDILLVDDVQFIEGKEY
TQEEFFHTFNTLHESGKQIVLAADRSPHLIPRLQERLCSRFSMGLIAEIQSPDIETRMAILKKKAEYEGMNLPADVIEYI
ATTYTSNIRELEGALIRAVAYVSISGLPMSVETIQPILNPPSEPKEITADMITDVVCEEFGIDRDSLLGSSRKRDISQAR
QIAMFLMRHYTNLSLPKIGDYFGGKDHTTVLYSCEKVSQLQRQSLQFERQLQKLVERLRVVANSRSS
>Mature_467_residues
MDISLDQLWDEALCHLQVQLSRPTFEAWIKTARAESLVDNRLTICTPSEWARGWLQKHYASTITEVVQRVAGIPLQVEFS
VSPHASVEAEPPSRAISPTSGRAGSLPASTTLGLEVGGSLPMRAPDLNPKYSFSRFVVGPNNRMAHAAALAVADKPGRAY
NPLFLCGGVGLGKTHLMQAIGHYQLEANPQAKVFYVSTERFTNDLIDAIRRDSMQSFREHYRDVDILLVDDVQFIEGKEY
TQEEFFHTFNTLHESGKQIVLAADRSPHLIPRLQERLCSRFSMGLIAEIQSPDIETRMAILKKKAEYEGMNLPADVIEYI
ATTYTSNIRELEGALIRAVAYVSISGLPMSVETIQPILNPPSEPKEITADMITDVVCEEFGIDRDSLLGSSRKRDISQAR
QIAMFLMRHYTNLSLPKIGDYFGGKDHTTVLYSCEKVSQLQRQSLQFERQLQKLVERLRVVANSRSS

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=471, Percent_Identity=39.4904458598726, Blast_Score=339, Evalue=2e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 52328; Mature: 52328

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISLDQLWDEALCHLQVQLSRPTFEAWIKTARAESLVDNRLTICTPSEWARGWLQKHYA
CCCCHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHH
STITEVVQRVAGIPLQVEFSVSPHASVEAEPPSRAISPTSGRAGSLPASTTLGLEVGGSL
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECEEECCCC
PMRAPDLNPKYSFSRFVVGPNNRMAHAAALAVADKPGRAYNPLFLCGGVGLGKTHLMQAI
CCCCCCCCCCCCCEEEEECCCCCHHHHHHEEEECCCCCCCCCEEEECCCCCCHHHHHHHH
GHYQLEANPQAKVFYVSTERFTNDLIDAIRRDSMQSFREHYRDVDILLVDDVQFIEGKEY
HCCEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCH
TQEEFFHTFNTLHESGKQIVLAADRSPHLIPRLQERLCSRFSMGLIAEIQSPDIETRMAI
HHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHEECCCCCHHHHHHH
LKKKAEYEGMNLPADVIEYIATTYTSNIRELEGALIRAVAYVSISGLPMSVETIQPILNP
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHCCC
PSEPKEITADMITDVVCEEFGIDRDSLLGSSRKRDISQARQIAMFLMRHYTNLSLPKIGD
CCCHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
YFGGKDHTTVLYSCEKVSQLQRQSLQFERQLQKLVERLRVVANSRSS
HCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDISLDQLWDEALCHLQVQLSRPTFEAWIKTARAESLVDNRLTICTPSEWARGWLQKHYA
CCCCHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHH
STITEVVQRVAGIPLQVEFSVSPHASVEAEPPSRAISPTSGRAGSLPASTTLGLEVGGSL
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECEEECCCC
PMRAPDLNPKYSFSRFVVGPNNRMAHAAALAVADKPGRAYNPLFLCGGVGLGKTHLMQAI
CCCCCCCCCCCCCEEEEECCCCCHHHHHHEEEECCCCCCCCCEEEECCCCCCHHHHHHHH
GHYQLEANPQAKVFYVSTERFTNDLIDAIRRDSMQSFREHYRDVDILLVDDVQFIEGKEY
HCCEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCH
TQEEFFHTFNTLHESGKQIVLAADRSPHLIPRLQERLCSRFSMGLIAEIQSPDIETRMAI
HHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHEECCCCCHHHHHHH
LKKKAEYEGMNLPADVIEYIATTYTSNIRELEGALIRAVAYVSISGLPMSVETIQPILNP
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHCCC
PSEPKEITADMITDVVCEEFGIDRDSLLGSSRKRDISQARQIAMFLMRHYTNLSLPKIGD
CCCHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
YFGGKDHTTVLYSCEKVSQLQRQSLQFERQLQKLVERLRVVANSRSS
HCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA