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The map label for this gene is atpB

Identifier: 86606759

GI number: 86606759

Start: 2134252

End: 2134998

Strand: Reverse

Name: atpB

Synonym: CYA_2119

Alternate gene names: 86606759

Gene position: 2134998-2134252 (Counterclockwise)

Preceding gene: 86606760

Following gene: 86606758

Centisome position: 72.8

GC content: 54.89

Gene sequence:

>747_bases
ATGAACCTGTTCTTCTCCGCTCCTCCTCTGGTAGCAGAACTTGAGGTTGGTCATCACCTTTACTGGCACCTGGGCAAATT
TACGGTTCACGGGCAAGTTTTGATTGCCAGTTGGATTGCCATCGCCCTGATCTTGACCGTGGTGCTGTTGGGGACTCGTC
AACTGCAGCGGGAGCCCGCTGGTCTGCAAAACTTTATCGAGTACACCCTGGAGTTTGTCCAAAGCATTGCCCGTGCCCAG
ATTGGTGAGAAAAACTTCCGGCCCTGGGTGCCCTACGTTGGCACCTTGTTCCTGTTTATTTTTGTCTCCAACTGGATGGG
CAATCTCTTCCCCTGGAAGTTGATTCCCCTGCCGGAAGGAGAGCTGGCCTCTCCCACCAACGACATCAACACCACCGCCG
GCTTGGCGCTGCTCACCAGCGTCATGTATTTCGTGGCCGGTATCAGCAAGCGAGGGCTGTCTTACTTTAAGAAGTACATC
GAGCCCACGCCAGTTCTGTTGCCCATCAACGTCCTGGAAGACTTCACCAAGCCCCTCTCCCTGAGTTTCCGTCTGTTCGG
CAACATCTTGGCAGAAGAGCTGGTGATTGCGGTGTTGGTGTTGCTGGTGCCGTTGTTGATCCCGGTGCCGGTGATGATCC
TATTTCTGTTTACGGGGGCCATTCAGGCTTTGATCTTCTCCACCCTCTCGGCCGCTTACATTGGAGAGGCGCTGGAAGGT
CATGGGGGTGGGGATCACCACGATTGA

Upstream 100 bases:

>100_bases
AGATTTTGCCCATTTTCTTGGGGTTCATGACCTACAAGGTCACCCTGCTGATTTATCTTGTTCAGACCTTGACCCGTTTA
TCTTCTTCTGCGTGATGCTC

Downstream 100 bases:

>100_bases
CCTGCGGAGGGAAGGTGGGGACTTCTACTCAGTTCAACGCCCCCTCTCCTTCAAAGGTCGTCGCAAGGGATCCCTTCTCT
GGTAAGGTTTGTTGGGGCCG

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNLFFSAPPLVAELEVGHHLYWHLGKFTVHGQVLIASWIAIALILTVVLLGTRQLQREPAGLQNFIEYTLEFVQSIARAQ
IGEKNFRPWVPYVGTLFLFIFVSNWMGNLFPWKLIPLPEGELASPTNDINTTAGLALLTSVMYFVAGISKRGLSYFKKYI
EPTPVLLPINVLEDFTKPLSLSFRLFGNILAEELVIAVLVLLVPLLIPVPVMILFLFTGAIQALIFSTLSAAYIGEALEG
HGGGDHHD

Sequences:

>Translated_248_residues
MNLFFSAPPLVAELEVGHHLYWHLGKFTVHGQVLIASWIAIALILTVVLLGTRQLQREPAGLQNFIEYTLEFVQSIARAQ
IGEKNFRPWVPYVGTLFLFIFVSNWMGNLFPWKLIPLPEGELASPTNDINTTAGLALLTSVMYFVAGISKRGLSYFKKYI
EPTPVLLPINVLEDFTKPLSLSFRLFGNILAEELVIAVLVLLVPLLIPVPVMILFLFTGAIQALIFSTLSAAYIGEALEG
HGGGDHHD
>Mature_248_residues
MNLFFSAPPLVAELEVGHHLYWHLGKFTVHGQVLIASWIAIALILTVVLLGTRQLQREPAGLQNFIEYTLEFVQSIARAQ
IGEKNFRPWVPYVGTLFLFIFVSNWMGNLFPWKLIPLPEGELASPTNDINTTAGLALLTSVMYFVAGISKRGLSYFKKYI
EPTPVLLPINVLEDFTKPLSLSFRLFGNILAEELVIAVLVLLVPLLIPVPVMILFLFTGAIQALIFSTLSAAYIGEALEG
HGGGDHHD

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=203, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_SYNJA (Q2JSV5)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_475522.1
- ProteinModelPortal:   Q2JSV5
- STRING:   Q2JSV5
- GeneID:   3899108
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_2119
- TIGR:   CYA_2119
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   LHGQVFL
- ProtClustDB:   PRK05815
- BioCyc:   SSP321327:CYA_2119-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 27485; Mature: 27485

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x156e7a2c)-; HASH(0x163ce2ec)-; HASH(0x165be6e0)-; HASH(0x15f29bf0)-; HASH(0x15dcbcfc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFFSAPPLVAELEVGHHLYWHLGKFTVHGQVLIASWIAIALILTVVLLGTRQLQREPA
CCCCCCCCCHHHHHHHCHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLQNFIEYTLEFVQSIARAQIGEKNFRPWVPYVGTLFLFIFVSNWMGNLFPWKLIPLPEG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCC
ELASPTNDINTTAGLALLTSVMYFVAGISKRGLSYFKKYIEPTPVLLPINVLEDFTKPLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCHHHH
LSFRLFGNILAEELVIAVLVLLVPLLIPVPVMILFLFTGAIQALIFSTLSAAYIGEALEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HGGGDHHD
CCCCCCCH
>Mature Secondary Structure
MNLFFSAPPLVAELEVGHHLYWHLGKFTVHGQVLIASWIAIALILTVVLLGTRQLQREPA
CCCCCCCCCHHHHHHHCHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLQNFIEYTLEFVQSIARAQIGEKNFRPWVPYVGTLFLFIFVSNWMGNLFPWKLIPLPEG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCC
ELASPTNDINTTAGLALLTSVMYFVAGISKRGLSYFKKYIEPTPVLLPINVLEDFTKPLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCHHHH
LSFRLFGNILAEELVIAVLVLLVPLLIPVPVMILFLFTGAIQALIFSTLSAAYIGEALEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HGGGDHHD
CCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA