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The map label for this gene is ppiA [C]

Identifier: 86606728

GI number: 86606728

Start: 2105977

End: 2107104

Strand: Reverse

Name: ppiA [C]

Synonym: CYA_2088

Alternate gene names: 86606728

Gene position: 2107104-2105977 (Counterclockwise)

Preceding gene: 86606729

Following gene: 86606723

Centisome position: 71.85

GC content: 62.59

Gene sequence:

>1128_bases
ATGACACAGCGTGCCCAGCAGGGATCCGCAGTTGGCAGCAATCGGTGGGAGTGGGGAAGAAGATCACTCCGGCTGGTCTT
AGCGGCTGTGTTGCTTTGGACGATTTGGCTGGGTGGGATCCCGGCCCTGGCGCTGCCGCAAGGGGATGCCATTACGGATC
CGCGAACCCTCTTGCGGCGGGCGCTGCCCATCCAAGACAGTCGGATCTGGGAAATTGACGAGTCCATCACCAAAATCGAG
GCCGACCTGAAGTACAACCGCTGGTCGGCGGTGCGGGGGGATGTGCGCCAGGTGGAGCGGCTCCTGGATCGCTATGCGGA
TCCCCTGCTGGCGGAGTTGCCCCCCGAGCAGGCTGCCGCCGCCTCTGAAGCAATAGCCGCCCTACGCCAGGAGTTGCAGC
TCATCAGCCAGGCCACGGAGCGCAAATCCAAGGGCAAGGAGGAAGCCCGCGCCGCCTACGACCGCCTCATAGACGACTTG
GGATCCCTGGAGAACAACTGGGTGGGGGCCTTCCCCTACGAGGTACCTGATGAGTACGCCGACAAGCCGCAGCTCCTGGG
CCGGGCAGAAGTGGAGCTGAACACCACCGCCGGGCGCATGGTGATCACCCTGGATGGCTATAGTGCTCCAATAACTGCTG
GCAACTTCGCTGACCTAGTGCAGCGGGGCTTCTACGATGGCCTGACCTTTGACCGAGTGGAGAAATTCTTCCTAGTGCAA
GCTGGAGATCCCCCTGGCCCTGCCGACGGCTATGTGGATCCGGCCACCGGCAGAGTCCGCACCATCCCCATGGAGATCCG
GGTCAAGGGTGAGGTAATGCCCCGCTACGGCCAAACCTTCGATCAACTGGGCCTGTGGGATGTGGAGCCGGCCCTGCCCT
TTGCTGCCGAAGGGACGGTGGCCATGGCCCGCTATCCCGAGGATCCCAACAGCGCCTCTTCTCAGTTCTTTATCTTTATG
GCCGAGCCGGATCTCACTCCCGCCGGCCTCAACCTCATGGATGGCCGCTACGCCGTGTTCGGCTATGTTACCGAGGGCAC
CGAGGTGCTGCGCAAGATCAAGCTGGGGGATCAGATCCTGAGCGCCCGGCTGATCTCAGGCCAAGAAAATCTCAGGAATG
GGGCGTAG

Upstream 100 bases:

>100_bases
TGAAGGCGACTTCACCCCCCTCTTTCGCAGCAACGCTTGCCGCCAGCAACGCTAGAATGCCAGGCTGAGAGCAAAAGCAG
TGTCGGCAACGGGTGAAGAC

Downstream 100 bases:

>100_bases
GGATTTTGCATCACTATCTCCTACCTTTGCCCTTTTGAGTGGCTAGAAGGCGCGGCTGAGGGCAGTTCCCGGGCCCTGAA
ACGCCAGCCAAGAGATCAGA

Product: peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Products: NA

Alternate protein names: Putative thylakoid lumen PPIase; Putative thylakoid lumen rotamase [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTQRAQQGSAVGSNRWEWGRRSLRLVLAAVLLWTIWLGGIPALALPQGDAITDPRTLLRRALPIQDSRIWEIDESITKIE
ADLKYNRWSAVRGDVRQVERLLDRYADPLLAELPPEQAAAASEAIAALRQELQLISQATERKSKGKEEARAAYDRLIDDL
GSLENNWVGAFPYEVPDEYADKPQLLGRAEVELNTTAGRMVITLDGYSAPITAGNFADLVQRGFYDGLTFDRVEKFFLVQ
AGDPPGPADGYVDPATGRVRTIPMEIRVKGEVMPRYGQTFDQLGLWDVEPALPFAAEGTVAMARYPEDPNSASSQFFIFM
AEPDLTPAGLNLMDGRYAVFGYVTEGTEVLRKIKLGDQILSARLISGQENLRNGA

Sequences:

>Translated_375_residues
MTQRAQQGSAVGSNRWEWGRRSLRLVLAAVLLWTIWLGGIPALALPQGDAITDPRTLLRRALPIQDSRIWEIDESITKIE
ADLKYNRWSAVRGDVRQVERLLDRYADPLLAELPPEQAAAASEAIAALRQELQLISQATERKSKGKEEARAAYDRLIDDL
GSLENNWVGAFPYEVPDEYADKPQLLGRAEVELNTTAGRMVITLDGYSAPITAGNFADLVQRGFYDGLTFDRVEKFFLVQ
AGDPPGPADGYVDPATGRVRTIPMEIRVKGEVMPRYGQTFDQLGLWDVEPALPFAAEGTVAMARYPEDPNSASSQFFIFM
AEPDLTPAGLNLMDGRYAVFGYVTEGTEVLRKIKLGDQILSARLISGQENLRNGA
>Mature_374_residues
TQRAQQGSAVGSNRWEWGRRSLRLVLAAVLLWTIWLGGIPALALPQGDAITDPRTLLRRALPIQDSRIWEIDESITKIEA
DLKYNRWSAVRGDVRQVERLLDRYADPLLAELPPEQAAAASEAIAALRQELQLISQATERKSKGKEEARAAYDRLIDDLG
SLENNWVGAFPYEVPDEYADKPQLLGRAEVELNTTAGRMVITLDGYSAPITAGNFADLVQRGFYDGLTFDRVEKFFLVQA
GDPPGPADGYVDPATGRVRTIPMEIRVKGEVMPRYGQTFDQLGLWDVEPALPFAAEGTVAMARYPEDPNSASSQFFIFMA
EPDLTPAGLNLMDGRYAVFGYVTEGTEVLRKIKLGDQILSARLISGQENLRNGA

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Required for the assembly and stabilization of PSII [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Cellular thylakoid lumen (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706339, Length=166, Percent_Identity=31.3253012048193, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17506311, Length=164, Percent_Identity=31.7073170731707, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17539496, Length=160, Percent_Identity=30.625, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17986117, Length=165, Percent_Identity=30.3030303030303, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR002130
- InterPro:   IPR023222 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 41513; Mature: 41382

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRAQQGSAVGSNRWEWGRRSLRLVLAAVLLWTIWLGGIPALALPQGDAITDPRTLLRR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHH
ALPIQDSRIWEIDESITKIEADLKYNRWSAVRGDVRQVERLLDRYADPLLAELPPEQAAA
HCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHH
ASEAIAALRQELQLISQATERKSKGKEEARAAYDRLIDDLGSLENNWVGAFPYEVPDEYA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHC
DKPQLLGRAEVELNTTAGRMVITLDGYSAPITAGNFADLVQRGFYDGLTFDRVEKFFLVQ
CCCHHCCCEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHCEEEEEE
AGDPPGPADGYVDPATGRVRTIPMEIRVKGEVMPRYGQTFDQLGLWDVEPALPFAAEGTV
CCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCHHHHCCCEECCCCCCCCCCCCE
AMARYPEDPNSASSQFFIFMAEPDLTPAGLNLMDGRYAVFGYVTEGTEVLRKIKLGDQIL
EEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHH
SARLISGQENLRNGA
HHHHHCCHHHHCCCC
>Mature Secondary Structure 
TQRAQQGSAVGSNRWEWGRRSLRLVLAAVLLWTIWLGGIPALALPQGDAITDPRTLLRR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHH
ALPIQDSRIWEIDESITKIEADLKYNRWSAVRGDVRQVERLLDRYADPLLAELPPEQAAA
HCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHH
ASEAIAALRQELQLISQATERKSKGKEEARAAYDRLIDDLGSLENNWVGAFPYEVPDEYA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHC
DKPQLLGRAEVELNTTAGRMVITLDGYSAPITAGNFADLVQRGFYDGLTFDRVEKFFLVQ
CCCHHCCCEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHCEEEEEE
AGDPPGPADGYVDPATGRVRTIPMEIRVKGEVMPRYGQTFDQLGLWDVEPALPFAAEGTV
CCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCHHHHCCCEECCCCCCCCCCCCE
AMARYPEDPNSASSQFFIFMAEPDLTPAGLNLMDGRYAVFGYVTEGTEVLRKIKLGDQIL
EEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHH
SARLISGQENLRNGA
HHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]