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The map label for this gene is xseA

Identifier: 86606620

GI number: 86606620

Start: 1994055

End: 1995290

Strand: Reverse

Name: xseA

Synonym: CYA_1976

Alternate gene names: 86606620

Gene position: 1995290-1994055 (Counterclockwise)

Preceding gene: 86606627

Following gene: 86606619

Centisome position: 68.03

GC content: 67.39

Gene sequence:

>1236_bases
ATGTTGTTCAGTAAATTCAGGACTAGAGGCTTACCCCTGCTCTCGGTGGGGGGAGTGTCCGGCTACTTGAAATCGCTGCT
GGCCGGGGATCCCTACCTGGCCAGGCTGTGGGTGGTGGGAGAAGTCTCCAGTTGCCAGCGCAGCCGCAACGGCCACCTGT
TCCTGACCCTGGTGGATCCGGAAAGCGGCGACCTCCTCAAGGGGGTTGTGTGGCAAAGTCAGACTGCCCGGCTCAGCTTC
TGGCCAGAAGTGGGGCAACGGGTGCTGGCCCTGGGTCAACTTGGCATCTACAGCGGCGGCAGCTACTACCGCCTGGTTAT
CTGGCAACTGCTGCCGGCGGGCGAGGGGCTGTTGGCGTGGCGGTTTCAGCAGCTTAAGGCCCGCCTTGCCGCCGAAGGCC
TGTTCGACAACCAGCGGCCCCTGCCCACCCACCCTCAGTGTATTGCCGTCGTCAGCTCTCCCGACGCCGCTGGCTGGGGC
GATATCCGCCGCACCCTCAACCAGCGCTACCCCGGGCTGCGGGTGCTGTTTGCGCCAGCCCAGGTGCAGGGGGAGGCGGC
CCCGGAGTCGATTGTGCGGGCCATTCGCCGGGTGGAGCGGGACGGGCGGGCGGAAGTGCTGATCGTGGCCCGGGGGGGCG
GATCCGGCGAGGACTTGGCCTGCTTTAACGACGAGCGGGTGGTGCGGGCCATTGCCGAGTGCTCCATTCCGGTGGTGACC
GGGATCGGCCACCAGCGGGATGAGACCTTAGCTGACTACGCTGCTGACTATGCGGCGCACACCCCCACAGCGGCCGCCGA
GCGAGTTGTGCCCGATCTGCGGGAACTGCAGCGCCAGGCATTCCAGTTGCGCCAGCAGCTTGTCGAGCGCACCCTGCATG
CTCTGGAAAAAGCTGAACAGCGTTGGCACCACGCCCAGCGCCGCCTAGCCCAGGTGCATCCGGAGCGGCTGCTGCAGCAG
GCCCAGGAGCGCCTAGCCCAACAGCAGCAGCGCCTGGTCCAGGCCGTGCGCCACCGTCTCCAGCAGCAGCAACAGCGCCA
CCAAGCTCTCCAGCAGCACCTGCAAGCCCTCGATCCTGCCGCCGTTCTCAGGCGGGGCTATGCCCTGGTGCGCGACGAGC
GGGGATCCCTGGTCCGCAGCCACCGCCTGCCGCCCCAGACCCGGCTGAGGATACAACTGGCCTCGGGCAGCCTCTGGGCC
CGAGTGGAGGAGAGCCATGAGCCGCCGCAAACGTGA

Upstream 100 bases:

>100_bases
TATTTAGTTCCAATCGGGTACAAAAACCTAGCAACATAACTTTGGGATAGCGCGGCAGCACGCTTAATTCAGTGTGGCTA
TTTTAGTTCCGTAAGACAAT

Downstream 100 bases:

>100_bases
GGATCCCTGGCGCTACGAAGCAGCCATCGCCGAAGTGGAAAGTCTGATTGCCCAGATCGAATCGGGAGAGCTGGATCTGG
CGGAGGTGGTGGAGCGCTTC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MLFSKFRTRGLPLLSVGGVSGYLKSLLAGDPYLARLWVVGEVSSCQRSRNGHLFLTLVDPESGDLLKGVVWQSQTARLSF
WPEVGQRVLALGQLGIYSGGSYYRLVIWQLLPAGEGLLAWRFQQLKARLAAEGLFDNQRPLPTHPQCIAVVSSPDAAGWG
DIRRTLNQRYPGLRVLFAPAQVQGEAAPESIVRAIRRVERDGRAEVLIVARGGGSGEDLACFNDERVVRAIAECSIPVVT
GIGHQRDETLADYAADYAAHTPTAAAERVVPDLRELQRQAFQLRQQLVERTLHALEKAEQRWHHAQRRLAQVHPERLLQQ
AQERLAQQQQRLVQAVRHRLQQQQQRHQALQQHLQALDPAAVLRRGYALVRDERGSLVRSHRLPPQTRLRIQLASGSLWA
RVEESHEPPQT

Sequences:

>Translated_411_residues
MLFSKFRTRGLPLLSVGGVSGYLKSLLAGDPYLARLWVVGEVSSCQRSRNGHLFLTLVDPESGDLLKGVVWQSQTARLSF
WPEVGQRVLALGQLGIYSGGSYYRLVIWQLLPAGEGLLAWRFQQLKARLAAEGLFDNQRPLPTHPQCIAVVSSPDAAGWG
DIRRTLNQRYPGLRVLFAPAQVQGEAAPESIVRAIRRVERDGRAEVLIVARGGGSGEDLACFNDERVVRAIAECSIPVVT
GIGHQRDETLADYAADYAAHTPTAAAERVVPDLRELQRQAFQLRQQLVERTLHALEKAEQRWHHAQRRLAQVHPERLLQQ
AQERLAQQQQRLVQAVRHRLQQQQQRHQALQQHLQALDPAAVLRRGYALVRDERGSLVRSHRLPPQTRLRIQLASGSLWA
RVEESHEPPQT
>Mature_411_residues
MLFSKFRTRGLPLLSVGGVSGYLKSLLAGDPYLARLWVVGEVSSCQRSRNGHLFLTLVDPESGDLLKGVVWQSQTARLSF
WPEVGQRVLALGQLGIYSGGSYYRLVIWQLLPAGEGLLAWRFQQLKARLAAEGLFDNQRPLPTHPQCIAVVSSPDAAGWG
DIRRTLNQRYPGLRVLFAPAQVQGEAAPESIVRAIRRVERDGRAEVLIVARGGGSGEDLACFNDERVVRAIAECSIPVVT
GIGHQRDETLADYAADYAAHTPTAAAERVVPDLRELQRQAFQLRQQLVERTLHALEKAEQRWHHAQRRLAQVHPERLLQQ
AQERLAQQQQRLVQAVRHRLQQQQQRHQALQQHLQALDPAAVLRRGYALVRDERGSLVRSHRLPPQTRLRIQLASGSLWA
RVEESHEPPQT

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=414, Percent_Identity=34.2995169082126, Blast_Score=228, Evalue=7e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 46148; Mature: 46148

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFSKFRTRGLPLLSVGGVSGYLKSLLAGDPYLARLWVVGEVSSCQRSRNGHLFLTLVDP
CCCHHHHHCCCCEEEECCHHHHHHHHHCCCCHHEHEEEEECHHHHHHCCCCCEEEEEECC
ESGDLLKGVVWQSQTARLSFWPEVGQRVLALGQLGIYSGGSYYRLVIWQLLPAGEGLLAW
CCCCHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHH
RFQQLKARLAAEGLFDNQRPLPTHPQCIAVVSSPDAAGWGDIRRTLNQRYPGLRVLFAPA
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECC
QVQGEAAPESIVRAIRRVERDGRAEVLIVARGGGSGEDLACFNDERVVRAIAECSIPVVT
HHCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEECHHHHHHHHHHCCCCEEE
GIGHQRDETLADYAADYAAHTPTAAAERVVPDLRELQRQAFQLRQQLVERTLHALEKAEQ
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWHHAQRRLAQVHPERLLQQAQERLAQQQQRLVQAVRHRLQQQQQRHQALQQHLQALDPA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AVLRRGYALVRDERGSLVRSHRLPPQTRLRIQLASGSLWARVEESHEPPQT
HHHHCCHHHEECCCCCHHHHCCCCCCCEEEEEEECCCCEEEEHHCCCCCCC
>Mature Secondary Structure
MLFSKFRTRGLPLLSVGGVSGYLKSLLAGDPYLARLWVVGEVSSCQRSRNGHLFLTLVDP
CCCHHHHHCCCCEEEECCHHHHHHHHHCCCCHHEHEEEEECHHHHHHCCCCCEEEEEECC
ESGDLLKGVVWQSQTARLSFWPEVGQRVLALGQLGIYSGGSYYRLVIWQLLPAGEGLLAW
CCCCHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHH
RFQQLKARLAAEGLFDNQRPLPTHPQCIAVVSSPDAAGWGDIRRTLNQRYPGLRVLFAPA
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECC
QVQGEAAPESIVRAIRRVERDGRAEVLIVARGGGSGEDLACFNDERVVRAIAECSIPVVT
HHCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEECHHHHHHHHHHCCCCEEE
GIGHQRDETLADYAADYAAHTPTAAAERVVPDLRELQRQAFQLRQQLVERTLHALEKAEQ
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWHHAQRRLAQVHPERLLQQAQERLAQQQQRLVQAVRHRLQQQQQRHQALQQHLQALDPA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AVLRRGYALVRDERGSLVRSHRLPPQTRLRIQLASGSLWARVEESHEPPQT
HHHHCCHHHEECCCCCHHHHCCCCCCCEEEEEEECCCCEEEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]