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The map label for this gene is gacS [H]

Identifier: 86606313

GI number: 86606313

Start: 1653665

End: 1658044

Strand: Reverse

Name: gacS [H]

Synonym: CYA_1657

Alternate gene names: 86606313

Gene position: 1658044-1653665 (Counterclockwise)

Preceding gene: 86606314

Following gene: 86606312

Centisome position: 56.54

GC content: 62.15

Gene sequence:

>4380_bases
ATGCACAGAGAGCTATGGGCGGTAGGGAAAACGGTGGGCCTGGTGGATCCCCCTGGCCTTGCCTTTTGGCTGCTGGGATC
CCTCTTCTTGGCTCTCCTGCTGCTTGGCGTCAGCCTGGGGGAAAGTCAGCTGCTTTCTGTCTTCAGAGGGATCCTGGGAT
CCCTTTCTCGAAGATTTCCCTTCCAACCTCCTAGAGGCACCCCCAGCCCAGAGGCTCGTTTTCGGGCAGCCTTGGAAGCC
AGCTTGGATGCTATTTACCTGCTGGAGGCGGTGCGGGATCCCGTTACCCGCGAGATCCTCGACTTTGTCTTTGTGGATGT
CAACGCCAAGGGGGAAGAGCTCATTTCTCTCCAGCGCCGGCAGATCATCGGCCAGCGGCTGTGCGAGCTGCTGCCCATCA
ACCGCTGGGGGGGCTTTTTTGAGAAATACAAGCGAGTGGTGGAAACCGGCATTCCTCTGGAAGAGGAGTTCCCCATTTCG
GGGCAGCCGGGCTTGAAGGCCAGCTGGATCCATCACCAAGTGGTGCCGGTGGGAGACGGGATCCTCATCACCAGCCGCGA
CATCAGCGAGCAGGTCCAGATCAAGCAAGCCCTGGAGGCAAGCGAGTTGCGCTACCGGGCCCTCTATGAGGCGATCCCGG
ATTTGATTTTCGAGATTGACCCTGAGGGGCTGATTCTCAACTGCAAGCCTTCTCCCTACGTCCCCACCCAGCATCCGCCC
GAGTTTTGTGTGGGTCGCCGCGCCCAAGACGTGTTTCCCAGCTCTTTCGGAGAGCAGTATCAGCTTTTAGCAGGGCGGGC
CCTGTCCACTCAAACGCCACAGTATCTGGAGTACGAAATGGTGCTCCCCGCCGCTGCCGCAAACGAGTCTGAGCCGGCAA
TCCGCCGCTATCAGAAGGCTTGCGTCGTTGCCTATGGCAGAGATAGAGTCTACGTTTTGGTGCGGGATATCACCAAGCGG
AAAGAGGCGGAGTTGGCCCTTAGAGAAATGGAAGCCACCCAGCGGGCCATTCTCCAAGCCATCCCCGACCTCATCCTTCG
CCTGAATAGCCAGGGCATCTGCCTGAGCTCTATTCCCGGAGGCGATGTCCATCTTTGCTGCCCAGCAGAGCGCCACTTAG
GTCGATCCCTCCAGGAGATTCTGCCGCCAGCGCTGGCCGAGCAGCGGCTTTTCTATGTTCAGCAAGCCCTGGCCACCCAA
ACCCAACAGCGCTACGAGTACAGCATTGAAGTTCAAGGGGAGGTACGCCACGAAGAAGCCCGCATTGTGCCTCTGAACAG
CCAGGAAGTCCTGGTGATCGTGCGGGATATTACAGAAGCCAAGCAGGCAGAGCTGGCCTTGAAAGCCGCTGAACAGCTGC
AGCGAGCCATTCTAGAAGCCATTCCCGACTTGATCTTCCGCCTTGATAGCCAGGGCATTTGCTTGAGCTTTATCTCGGGG
GGCGAGGTTCTTCTCTATGGCTCACCCGACACCTACGTGGGCCGATCCCTGCAGGAGCTTTTGCCACCGGAGTTGGCCGA
GCGGCGGCTTTTCTTTGTTCAGCAGGCTATAGCTACCCAGACGCGGCAGCGCTACGACCAAAGCATCGAGATTGAAGGGG
AGACCCGCCACGAAGAGGTGCGCATTGTGCCCCTCAACCCCCAAGAGGTGGTGGTGATCGTCCGCGATGTAACCGACAGG
GTGCGATCCCAGCAGGCCGTCCAGGAAAGCGAGCAGAAGTTCCGGGCTCTGTTTGAGAATGCCGCTGTGGCCATCCTCAT
CCGTCATGCCGAGACCGGCGAGATCCTGGAGGCCAACTCCCAAGCCATTGCCGCCTACGGGTTTTCCAGCCTGGAGGAGC
TGCGGGCCTTCGACGCTTGCGAGCAGTCTCCCTATCGCCGGGCTTTGCAGGGGAGGGAGTTTGCCTTGCAGCCCTACTTG
GAGCAGGCCCGCCAGCAGGGATCCGCCCGCTTTGAGTGGCAATGGCAGCGGCAGGATGGCCGAGTTGTCTGGGAAGACGT
GTTTGTGCAGCCCCTTGTCTTGCGCGGGATCCCGTGTTGGGTGTTTACCGCGGTGGACATCACTGCCCGCAAGTCGGCAG
AAGCGGAGCTGGAGCAGTTTTTCTCGGTGGCTCTGGATTTGCTTTGCATTGCCGATGCCCAAGGGTACTTTCGCCGTCTC
AACCGCGCCTGGGAGACCACCCTGGGCTATTCCCTGCAGGAGCTCCAGAGCCGACCCTTTTTGGAGTGGGTTCACCCGGA
AGATGTCCCCGCCACACAGGCCGCCATGCAGCAGCTTGTCGAAGAGAAACGGCTGGATCACTTCGTCAACCGCTACCGCA
CCCAGGACGGCAGCTATCGTTTCATCGAGTGGCGAGCCTCTTTGGCCGGATCCCTGGTCTACGCCGCCGGGCGGGACATC
ACCCTGGCCAAGCAGGCCCAAGAGCAGATGAAGGCGGCTATGGAAGCTGCCGAGGCGGCCAACCGCGCCAAGAGCGAGTT
CCTGGCCACCATCAGCCACGAGATCCGCACGCCCATCAACGCCATCATGGGCATGGCCGGCCTGTTGCTGGATACCTCTC
TCGATGCCCAGCAGCGGGATTGGGTGCAGACCATCCGCTACGGCAGCGAGGTGCTGCTCAGCCTCATCAACGACATCTTG
GATTTTTCCAAGATCGAGTCCCAGAAGCTGGAGCTGGAGGAAACGCCCTTCTCCTTGCCCCAGCTCATGGAGGAGCTCTT
GGATCTCATGGCCGCCCAGGCCCAGAGCAAAGATCTGGAGCTGGTGGCCTGGGTGGATCCGGCCCTGCCGGCCACCCTGG
TCGGGGATCCCAACCGCCTGCGCCAGATCCTGGCCAACCTCCTCAGCAACGCCATCAAGTTCACCCCCCAAGGGGAGGTG
GTGGTGACCGTCGAGGCCCAAGAGCAAGATCCCCAGGCCCAGGTGCAGTGGGTGAGCTTCCAGGTGCAGGACACCGGCAT
CGGCATCCCGCCGGAAAAGCAGGATCGCCTCTTCAAGCCCTTCAGCCAGGTGGACAGCTCCATCAGCCGCCAGTACGGCG
GCACCGGCCTGGGGCTGGCCATCAGCCAGCGCCTCTGTCAACTCATGGGCGGAACGATCTGGGTGCAAAGCCAGCCGGGT
CAGGGATCCACCTTTGGCTTCCGCATCCCCCTGAAGCTTCCGGATGCGGCCCTCTGGGCAACCCCCACCCCCGACCCAGC
TCTGGCCGGCCAGCGGGTTTTGCTGGTGGAAGACAACGCCAGCCAACGGCAACTTCTTGCGCGCCTACTGCAGTCCTGGG
GGATGCAGGTAACAGCCTGCAGCACGGTGGCGGAAGCCCAAGCCATAGCCAAGGCCCAGACTTTTGAGCTGGCCCTGGTG
GATACCAGCCTGCCCGACGGCGATGGACTGGCCCTGGCCAGGGCTCTGCAACAGGAGCAGCCCCCCCTGCGGCTTGTGCT
GCTGGTGGATCGCAGAGCCGCTTTGGCAAGCGCTGGCTCTCTTCCTGCCTTAGGTAAGCCGGTCAGGGCTTCTCAACTGC
GGGCTCTGCTGGGCCAGGAAAAAGTGCCTGCGGCTGCTTCCCACTTGAAACCCCAGCTCCCTCTGGCCAGCCGCTGCCCG
TTGCGCATCCTGGTAGCCGAAGACAACCCCGTCAACCAAAAGGTCATCCGCCTGATGCTGGAGCGGCTGGGCTATCAGCC
GGACATCGTGGCCAACGGCCTGGAAGCCCTGCAGGCGCTGCAACTGCGCGCCTACGACCTGGTCTTGATGGATCTGCACA
TGCCGGAGCTGGACGGCCTGGCCGCCACCCGCCGCATCCGCAGCGAACTTCCCCCAGAGCGCCAGCCGCGCATCCTCGCC
CTCACCGCCGATGCCTTCCTGGAAAGCCGCGCTGCTGCCGAAGCCGCCGGCGTCGATGGCTACCTGACCAAGCCCCTGCA
GCCGGCTGTGCTGGAGCGGGCCCTCCAGGAAGCTGCTCTCGATTTTGTCGGGGATCCAAAGCCAGAGCCGGCCCTGGATG
CCGCTGCCCTGGCCAGCCTGCAGAGCATGCTGGGATCCCCGGAAGACTGGCAGGAGATGATCCAAACCTACCGGCAAGAC
AGCCAGGCCCTGCTGGGATCCCTGCGCCAGGCCCTGGAGAGCCGGGATGTCCAAACCGTGGCCCAACTGGCCCACCGCCT
CAAGGGCAGCAGCAGAACCTTGGGGGCCAAGCTCTTAGCTCAACGCTGCCAGGCGCTGGAAAAGCTCGTTCGCAAGCCAT
CGGCCAACTCTGTAAACTGGGATACCATAGAGCAGGCCTTCCAGCGGTTGGAAGCCGAGTACCAGCGGGTTATCCTCGAA
TTATCGGCTAGCGCGCCAGGACCGCTTCTTTCTTCTCCAGGGGCCCATGCAGAGGCTTGA

Upstream 100 bases:

>100_bases
CATTTCCGCAAGTTAGCTGAGCTTCCTCTTTTGACCTCCAAGATAAGCTGGAAAGACTTGCTGGGATACTGTGGAAAGGG
GGTAGGAATCTCTGGGTTCT

Downstream 100 bases:

>100_bases
GAGCAACCTTTCGGCTGGATCCGTTCCTCAGACCGGAACGAGCTCTGCTGCGGCAGAGAAGCGGCCTCTCCTCCTCATTG
CCGACGATGATCCCAGCCAG

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1459; Mature: 1459

Protein sequence:

>1459_residues
MHRELWAVGKTVGLVDPPGLAFWLLGSLFLALLLLGVSLGESQLLSVFRGILGSLSRRFPFQPPRGTPSPEARFRAALEA
SLDAIYLLEAVRDPVTREILDFVFVDVNAKGEELISLQRRQIIGQRLCELLPINRWGGFFEKYKRVVETGIPLEEEFPIS
GQPGLKASWIHHQVVPVGDGILITSRDISEQVQIKQALEASELRYRALYEAIPDLIFEIDPEGLILNCKPSPYVPTQHPP
EFCVGRRAQDVFPSSFGEQYQLLAGRALSTQTPQYLEYEMVLPAAAANESEPAIRRYQKACVVAYGRDRVYVLVRDITKR
KEAELALREMEATQRAILQAIPDLILRLNSQGICLSSIPGGDVHLCCPAERHLGRSLQEILPPALAEQRLFYVQQALATQ
TQQRYEYSIEVQGEVRHEEARIVPLNSQEVLVIVRDITEAKQAELALKAAEQLQRAILEAIPDLIFRLDSQGICLSFISG
GEVLLYGSPDTYVGRSLQELLPPELAERRLFFVQQAIATQTRQRYDQSIEIEGETRHEEVRIVPLNPQEVVVIVRDVTDR
VRSQQAVQESEQKFRALFENAAVAILIRHAETGEILEANSQAIAAYGFSSLEELRAFDACEQSPYRRALQGREFALQPYL
EQARQQGSARFEWQWQRQDGRVVWEDVFVQPLVLRGIPCWVFTAVDITARKSAEAELEQFFSVALDLLCIADAQGYFRRL
NRAWETTLGYSLQELQSRPFLEWVHPEDVPATQAAMQQLVEEKRLDHFVNRYRTQDGSYRFIEWRASLAGSLVYAAGRDI
TLAKQAQEQMKAAMEAAEAANRAKSEFLATISHEIRTPINAIMGMAGLLLDTSLDAQQRDWVQTIRYGSEVLLSLINDIL
DFSKIESQKLELEETPFSLPQLMEELLDLMAAQAQSKDLELVAWVDPALPATLVGDPNRLRQILANLLSNAIKFTPQGEV
VVTVEAQEQDPQAQVQWVSFQVQDTGIGIPPEKQDRLFKPFSQVDSSISRQYGGTGLGLAISQRLCQLMGGTIWVQSQPG
QGSTFGFRIPLKLPDAALWATPTPDPALAGQRVLLVEDNASQRQLLARLLQSWGMQVTACSTVAEAQAIAKAQTFELALV
DTSLPDGDGLALARALQQEQPPLRLVLLVDRRAALASAGSLPALGKPVRASQLRALLGQEKVPAAASHLKPQLPLASRCP
LRILVAEDNPVNQKVIRLMLERLGYQPDIVANGLEALQALQLRAYDLVLMDLHMPELDGLAATRRIRSELPPERQPRILA
LTADAFLESRAAAEAAGVDGYLTKPLQPAVLERALQEAALDFVGDPKPEPALDAAALASLQSMLGSPEDWQEMIQTYRQD
SQALLGSLRQALESRDVQTVAQLAHRLKGSSRTLGAKLLAQRCQALEKLVRKPSANSVNWDTIEQAFQRLEAEYQRVILE
LSASAPGPLLSSPGAHAEA

Sequences:

>Translated_1459_residues
MHRELWAVGKTVGLVDPPGLAFWLLGSLFLALLLLGVSLGESQLLSVFRGILGSLSRRFPFQPPRGTPSPEARFRAALEA
SLDAIYLLEAVRDPVTREILDFVFVDVNAKGEELISLQRRQIIGQRLCELLPINRWGGFFEKYKRVVETGIPLEEEFPIS
GQPGLKASWIHHQVVPVGDGILITSRDISEQVQIKQALEASELRYRALYEAIPDLIFEIDPEGLILNCKPSPYVPTQHPP
EFCVGRRAQDVFPSSFGEQYQLLAGRALSTQTPQYLEYEMVLPAAAANESEPAIRRYQKACVVAYGRDRVYVLVRDITKR
KEAELALREMEATQRAILQAIPDLILRLNSQGICLSSIPGGDVHLCCPAERHLGRSLQEILPPALAEQRLFYVQQALATQ
TQQRYEYSIEVQGEVRHEEARIVPLNSQEVLVIVRDITEAKQAELALKAAEQLQRAILEAIPDLIFRLDSQGICLSFISG
GEVLLYGSPDTYVGRSLQELLPPELAERRLFFVQQAIATQTRQRYDQSIEIEGETRHEEVRIVPLNPQEVVVIVRDVTDR
VRSQQAVQESEQKFRALFENAAVAILIRHAETGEILEANSQAIAAYGFSSLEELRAFDACEQSPYRRALQGREFALQPYL
EQARQQGSARFEWQWQRQDGRVVWEDVFVQPLVLRGIPCWVFTAVDITARKSAEAELEQFFSVALDLLCIADAQGYFRRL
NRAWETTLGYSLQELQSRPFLEWVHPEDVPATQAAMQQLVEEKRLDHFVNRYRTQDGSYRFIEWRASLAGSLVYAAGRDI
TLAKQAQEQMKAAMEAAEAANRAKSEFLATISHEIRTPINAIMGMAGLLLDTSLDAQQRDWVQTIRYGSEVLLSLINDIL
DFSKIESQKLELEETPFSLPQLMEELLDLMAAQAQSKDLELVAWVDPALPATLVGDPNRLRQILANLLSNAIKFTPQGEV
VVTVEAQEQDPQAQVQWVSFQVQDTGIGIPPEKQDRLFKPFSQVDSSISRQYGGTGLGLAISQRLCQLMGGTIWVQSQPG
QGSTFGFRIPLKLPDAALWATPTPDPALAGQRVLLVEDNASQRQLLARLLQSWGMQVTACSTVAEAQAIAKAQTFELALV
DTSLPDGDGLALARALQQEQPPLRLVLLVDRRAALASAGSLPALGKPVRASQLRALLGQEKVPAAASHLKPQLPLASRCP
LRILVAEDNPVNQKVIRLMLERLGYQPDIVANGLEALQALQLRAYDLVLMDLHMPELDGLAATRRIRSELPPERQPRILA
LTADAFLESRAAAEAAGVDGYLTKPLQPAVLERALQEAALDFVGDPKPEPALDAAALASLQSMLGSPEDWQEMIQTYRQD
SQALLGSLRQALESRDVQTVAQLAHRLKGSSRTLGAKLLAQRCQALEKLVRKPSANSVNWDTIEQAFQRLEAEYQRVILE
LSASAPGPLLSSPGAHAEA
>Mature_1459_residues
MHRELWAVGKTVGLVDPPGLAFWLLGSLFLALLLLGVSLGESQLLSVFRGILGSLSRRFPFQPPRGTPSPEARFRAALEA
SLDAIYLLEAVRDPVTREILDFVFVDVNAKGEELISLQRRQIIGQRLCELLPINRWGGFFEKYKRVVETGIPLEEEFPIS
GQPGLKASWIHHQVVPVGDGILITSRDISEQVQIKQALEASELRYRALYEAIPDLIFEIDPEGLILNCKPSPYVPTQHPP
EFCVGRRAQDVFPSSFGEQYQLLAGRALSTQTPQYLEYEMVLPAAAANESEPAIRRYQKACVVAYGRDRVYVLVRDITKR
KEAELALREMEATQRAILQAIPDLILRLNSQGICLSSIPGGDVHLCCPAERHLGRSLQEILPPALAEQRLFYVQQALATQ
TQQRYEYSIEVQGEVRHEEARIVPLNSQEVLVIVRDITEAKQAELALKAAEQLQRAILEAIPDLIFRLDSQGICLSFISG
GEVLLYGSPDTYVGRSLQELLPPELAERRLFFVQQAIATQTRQRYDQSIEIEGETRHEEVRIVPLNPQEVVVIVRDVTDR
VRSQQAVQESEQKFRALFENAAVAILIRHAETGEILEANSQAIAAYGFSSLEELRAFDACEQSPYRRALQGREFALQPYL
EQARQQGSARFEWQWQRQDGRVVWEDVFVQPLVLRGIPCWVFTAVDITARKSAEAELEQFFSVALDLLCIADAQGYFRRL
NRAWETTLGYSLQELQSRPFLEWVHPEDVPATQAAMQQLVEEKRLDHFVNRYRTQDGSYRFIEWRASLAGSLVYAAGRDI
TLAKQAQEQMKAAMEAAEAANRAKSEFLATISHEIRTPINAIMGMAGLLLDTSLDAQQRDWVQTIRYGSEVLLSLINDIL
DFSKIESQKLELEETPFSLPQLMEELLDLMAAQAQSKDLELVAWVDPALPATLVGDPNRLRQILANLLSNAIKFTPQGEV
VVTVEAQEQDPQAQVQWVSFQVQDTGIGIPPEKQDRLFKPFSQVDSSISRQYGGTGLGLAISQRLCQLMGGTIWVQSQPG
QGSTFGFRIPLKLPDAALWATPTPDPALAGQRVLLVEDNASQRQLLARLLQSWGMQVTACSTVAEAQAIAKAQTFELALV
DTSLPDGDGLALARALQQEQPPLRLVLLVDRRAALASAGSLPALGKPVRASQLRALLGQEKVPAAASHLKPQLPLASRCP
LRILVAEDNPVNQKVIRLMLERLGYQPDIVANGLEALQALQLRAYDLVLMDLHMPELDGLAATRRIRSELPPERQPRILA
LTADAFLESRAAAEAAGVDGYLTKPLQPAVLERALQEAALDFVGDPKPEPALDAAALASLQSMLGSPEDWQEMIQTYRQD
SQALLGSLRQALESRDVQTVAQLAHRLKGSSRTLGAKLLAQRCQALEKLVRKPSANSVNWDTIEQAFQRLEAEYQRVILE
LSASAPGPLLSSPGAHAEA

Specific function: Forms part of a two-component regulatory system gacA/gacS(lemA). May be involved in lesion formation, swarming and in the production of extracellular protease, syringomycin and N- acyl-L-homoserine lactone (acyl-HSL). Required for pathogenicity on bean [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=643, Percent_Identity=32.0373250388802, Blast_Score=292, Evalue=9e-80,
Organism=Escherichia coli, GI145693157, Length=528, Percent_Identity=33.5227272727273, Blast_Score=253, Evalue=6e-68,
Organism=Escherichia coli, GI48994928, Length=534, Percent_Identity=34.6441947565543, Blast_Score=237, Evalue=4e-63,
Organism=Escherichia coli, GI87081816, Length=333, Percent_Identity=40.2402402402402, Blast_Score=231, Evalue=4e-61,
Organism=Escherichia coli, GI1788713, Length=471, Percent_Identity=31.2101910828025, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI1786600, Length=269, Percent_Identity=29.368029739777, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1788549, Length=355, Percent_Identity=26.7605633802817, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1786783, Length=240, Percent_Identity=32.5, Blast_Score=98, Evalue=4e-21,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=29.7413793103448, Blast_Score=95, Evalue=4e-20,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=29.957805907173, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=26.0869565217391, Blast_Score=81, Evalue=6e-16,
Organism=Escherichia coli, GI1790300, Length=252, Percent_Identity=26.984126984127, Blast_Score=80, Evalue=9e-16,
Organism=Escherichia coli, GI1786912, Length=250, Percent_Identity=27.6, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=249, Percent_Identity=28.5140562248996, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=27.0386266094421, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=118, Percent_Identity=34.7457627118644, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1790551, Length=224, Percent_Identity=30.8035714285714, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=214, Percent_Identity=27.1028037383178, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1790861, Length=236, Percent_Identity=25.8474576271186, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=77, Percent_Identity=51.9480519480519, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 162228; Mature: 162228

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRELWAVGKTVGLVDPPGLAFWLLGSLFLALLLLGVSLGESQLLSVFRGILGSLSRRFP
CCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
FQPPRGTPSPEARFRAALEASLDAIYLLEAVRDPVTREILDFVFVDVNAKGEELISLQRR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEEECCCCHHHHHHHHHH
QIIGQRLCELLPINRWGGFFEKYKRVVETGIPLEEEFPISGQPGLKASWIHHQVVPVGDG
HHHHHHHHHHCCCHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHEEEEECCCC
ILITSRDISEQVQIKQALEASELRYRALYEAIPDLIFEIDPEGLILNCKPSPYVPTQHPP
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCCCCCCCCH
EFCVGRRAQDVFPSSFGEQYQLLAGRALSTQTPQYLEYEMVLPAAAANESEPAIRRYQKA
HHHHCCCHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHH
CVVAYGRDRVYVLVRDITKRKEAELALREMEATQRAILQAIPDLILRLNSQGICLSSIPG
HEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
GDVHLCCPAERHLGRSLQEILPPALAEQRLFYVQQALATQTQQRYEYSIEVQGEVRHEEA
CCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCEECCCC
RIVPLNSQEVLVIVRDITEAKQAELALKAAEQLQRAILEAIPDLIFRLDSQGICLSFISG
EEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
GEVLLYGSPDTYVGRSLQELLPPELAERRLFFVQQAIATQTRQRYDQSIEIEGETRHEEV
CEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEE
RIVPLNPQEVVVIVRDVTDRVRSQQAVQESEQKFRALFENAAVAILIRHAETGEILEANS
EEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCEECCC
QAIAAYGFSSLEELRAFDACEQSPYRRALQGREFALQPYLEQARQQGSARFEWQWQRQDG
CEEEHHCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCC
RVVWEDVFVQPLVLRGIPCWVFTAVDITARKSAEAELEQFFSVALDLLCIADAQGYFRRL
CEEHHHHHHHHHHHCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHH
NRAWETTLGYSLQELQSRPFLEWVHPEDVPATQAAMQQLVEEKRLDHFVNRYRTQDGSYR
HHHHHHHHCCCHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FIEWRASLAGSLVYAAGRDITLAKQAQEQMKAAMEAAEAANRAKSEFLATISHEIRTPIN
EEEEHHHHHCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIMGMAGLLLDTSLDAQQRDWVQTIRYGSEVLLSLINDILDFSKIESQKLELEETPFSLP
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
QLMEELLDLMAAQAQSKDLELVAWVDPALPATLVGDPNRLRQILANLLSNAIKFTPQGEV
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHEECCCCCE
VVTVEAQEQDPQAQVQWVSFQVQDTGIGIPPEKQDRLFKPFSQVDSSISRQYGGTGLGLA
EEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCHHHH
ISQRLCQLMGGTIWVQSQPGQGSTFGFRIPLKLPDAALWATPTPDPALAGQRVLLVEDNA
HHHHHHHHHCCEEEEECCCCCCCCEEEEEEEECCCCCEECCCCCCCCCCCCEEEEEECCC
SQRQLLARLLQSWGMQVTACSTVAEAQAIAKAQTFELALVDTSLPDGDGLALARALQQEQ
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHCC
PPLRLVLLVDRRAALASAGSLPALGKPVRASQLRALLGQEKVPAAASHLKPQLPLASRCP
CCEEEEEEECCHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCC
LRILVAEDNPVNQKVIRLMLERLGYQPDIVANGLEALQALQLRAYDLVLMDLHMPELDGL
EEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHH
AATRRIRSELPPERQPRILALTADAFLESRAAAEAAGVDGYLTKPLQPAVLERALQEAAL
HHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
DFVGDPKPEPALDAAALASLQSMLGSPEDWQEMIQTYRQDSQALLGSLRQALESRDVQTV
HHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AQLAHRLKGSSRTLGAKLLAQRCQALEKLVRKPSANSVNWDTIEQAFQRLEAEYQRVILE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSASAPGPLLSSPGAHAEA
HCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHRELWAVGKTVGLVDPPGLAFWLLGSLFLALLLLGVSLGESQLLSVFRGILGSLSRRFP
CCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
FQPPRGTPSPEARFRAALEASLDAIYLLEAVRDPVTREILDFVFVDVNAKGEELISLQRR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEEECCCCHHHHHHHHHH
QIIGQRLCELLPINRWGGFFEKYKRVVETGIPLEEEFPISGQPGLKASWIHHQVVPVGDG
HHHHHHHHHHCCCHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHEEEEECCCC
ILITSRDISEQVQIKQALEASELRYRALYEAIPDLIFEIDPEGLILNCKPSPYVPTQHPP
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCCCCCCCCH
EFCVGRRAQDVFPSSFGEQYQLLAGRALSTQTPQYLEYEMVLPAAAANESEPAIRRYQKA
HHHHCCCHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHH
CVVAYGRDRVYVLVRDITKRKEAELALREMEATQRAILQAIPDLILRLNSQGICLSSIPG
HEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
GDVHLCCPAERHLGRSLQEILPPALAEQRLFYVQQALATQTQQRYEYSIEVQGEVRHEEA
CCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCEECCCC
RIVPLNSQEVLVIVRDITEAKQAELALKAAEQLQRAILEAIPDLIFRLDSQGICLSFISG
EEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
GEVLLYGSPDTYVGRSLQELLPPELAERRLFFVQQAIATQTRQRYDQSIEIEGETRHEEV
CEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEE
RIVPLNPQEVVVIVRDVTDRVRSQQAVQESEQKFRALFENAAVAILIRHAETGEILEANS
EEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCEECCC
QAIAAYGFSSLEELRAFDACEQSPYRRALQGREFALQPYLEQARQQGSARFEWQWQRQDG
CEEEHHCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCC
RVVWEDVFVQPLVLRGIPCWVFTAVDITARKSAEAELEQFFSVALDLLCIADAQGYFRRL
CEEHHHHHHHHHHHCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHH
NRAWETTLGYSLQELQSRPFLEWVHPEDVPATQAAMQQLVEEKRLDHFVNRYRTQDGSYR
HHHHHHHHCCCHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FIEWRASLAGSLVYAAGRDITLAKQAQEQMKAAMEAAEAANRAKSEFLATISHEIRTPIN
EEEEHHHHHCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIMGMAGLLLDTSLDAQQRDWVQTIRYGSEVLLSLINDILDFSKIESQKLELEETPFSLP
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
QLMEELLDLMAAQAQSKDLELVAWVDPALPATLVGDPNRLRQILANLLSNAIKFTPQGEV
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHEECCCCCE
VVTVEAQEQDPQAQVQWVSFQVQDTGIGIPPEKQDRLFKPFSQVDSSISRQYGGTGLGLA
EEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCHHHH
ISQRLCQLMGGTIWVQSQPGQGSTFGFRIPLKLPDAALWATPTPDPALAGQRVLLVEDNA
HHHHHHHHHCCEEEEECCCCCCCCEEEEEEEECCCCCEECCCCCCCCCCCCEEEEEECCC
SQRQLLARLLQSWGMQVTACSTVAEAQAIAKAQTFELALVDTSLPDGDGLALARALQQEQ
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHCC
PPLRLVLLVDRRAALASAGSLPALGKPVRASQLRALLGQEKVPAAASHLKPQLPLASRCP
CCEEEEEEECCHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCC
LRILVAEDNPVNQKVIRLMLERLGYQPDIVANGLEALQALQLRAYDLVLMDLHMPELDGL
EEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHH
AATRRIRSELPPERQPRILALTADAFLESRAAAEAAGVDGYLTKPLQPAVLERALQEAAL
HHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
DFVGDPKPEPALDAAALASLQSMLGSPEDWQEMIQTYRQDSQALLGSLRQALESRDVQTV
HHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AQLAHRLKGSSRTLGAKLLAQRCQALEKLVRKPSANSVNWDTIEQAFQRLEAEYQRVILE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSASAPGPLLSSPGAHAEA
HCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1314807 [H]