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The map label for this gene is eda

Identifier: 86606285

GI number: 86606285

Start: 1628283

End: 1629023

Strand: Reverse

Name: eda

Synonym: CYA_1625

Alternate gene names: 86606285

Gene position: 1629023-1628283 (Counterclockwise)

Preceding gene: 86606287

Following gene: 86606284

Centisome position: 55.55

GC content: 62.89

Gene sequence:

>741_bases
ATGGTGTTTGAGGGTTCTGAACAGAGCTTCAGAGAGGGATGGCGGCACCCCTGGCTACTCCATTTGTGGCAGCAGCCCCT
GATCGCGGTGATCCGCCTCTCGGCCAGCCCGGCCCAAGCCCTTGAGGGATCCACCCTGGCCATCCGGGCCGGGATCCGCC
ACATTGAGATCACTCCCCAAGTTCCCCGGTATCTGGAGTTGATTGCCCAACTGCGGCAAGACTACCCGCATTGCTGGGTA
GGGGTGGGCACGGTTTTAAATCGGCAGATGGCAGAGCAGGCTTGGCAGGCGGGAGCCCAATTCTATGTTTGCCCCTTTGC
GGACGAGAGCATCATCCGCTGGGGTCGGGAAGCAGGGCTGCCCATTGTGCCCGGCGCCCTCACCCCCGGCGAGATCTGGA
GGGCCTGGCAGGCCGGGGCAACGGCAGTAAAGGTGTTTCCGGCAGAAAGCCTTGGCGGATCCCGTTACCTGCGCCATCTG
CAACCGGTGCTGGGATCCCTGCCTTTGATCCCAACTGGGGGGGTTACCTTGGCCAATGCAGCAGAATATCTGCAGGCAGG
GGCCTGGGCTGTCGGCATCGCCGGGGATCTCTTCCCGGCGGAGCTTCTTTCCCAGCAAGGGGTTGATCCAGACAGTTGCC
GGCAAGAGCTGGAAAATCGGCTGCGGCAAACGCTACAACAGCTTGCCAGCCAGAGGGTCGCCGCAGCCTGGCCCGAACTT
CCGGGTGAACCCCCAGAGTAG

Upstream 100 bases:

>100_bases
CATTGTTTTACCGTCGGGCTGTTTGGTTATTTTTAATTGCAATTAAACTTAAAATCAACCCAAGCAAGGTAGAAATCGAT
GAGAGAGGGCTTTTCCACAG

Downstream 100 bases:

>100_bases
GGGGCGCGTTGACGCTCCCCGCACTTGAGTGGGGAGATGGCCGAGCACCCTGGCAGCAAACTTTGGAGGGCGCTGCCCAG
CCGCACCCCCGACATCCCTC

Product: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase

Products: NA

Alternate protein names: KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MVFEGSEQSFREGWRHPWLLHLWQQPLIAVIRLSASPAQALEGSTLAIRAGIRHIEITPQVPRYLELIAQLRQDYPHCWV
GVGTVLNRQMAEQAWQAGAQFYVCPFADESIIRWGREAGLPIVPGALTPGEIWRAWQAGATAVKVFPAESLGGSRYLRHL
QPVLGSLPLIPTGGVTLANAAEYLQAGAWAVGIAGDLFPAELLSQQGVDPDSCRQELENRLRQTLQQLASQRVAAAWPEL
PGEPPE

Sequences:

>Translated_246_residues
MVFEGSEQSFREGWRHPWLLHLWQQPLIAVIRLSASPAQALEGSTLAIRAGIRHIEITPQVPRYLELIAQLRQDYPHCWV
GVGTVLNRQMAEQAWQAGAQFYVCPFADESIIRWGREAGLPIVPGALTPGEIWRAWQAGATAVKVFPAESLGGSRYLRHL
QPVLGSLPLIPTGGVTLANAAEYLQAGAWAVGIAGDLFPAELLSQQGVDPDSCRQELENRLRQTLQQLASQRVAAAWPEL
PGEPPE
>Mature_246_residues
MVFEGSEQSFREGWRHPWLLHLWQQPLIAVIRLSASPAQALEGSTLAIRAGIRHIEITPQVPRYLELIAQLRQDYPHCWV
GVGTVLNRQMAEQAWQAGAQFYVCPFADESIIRWGREAGLPIVPGALTPGEIWRAWQAGATAVKVFPAESLGGSRYLRHL
QPVLGSLPLIPTGGVTLANAAEYLQAGAWAVGIAGDLFPAELLSQQGVDPDSCRQELENRLRQTLQQLASQRVAAAWPEL
PGEPPE

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI48994954, Length=182, Percent_Identity=32.967032967033, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1788156, Length=163, Percent_Identity=31.9018404907975, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.2.14 [H]

Molecular weight: Translated: 27047; Mature: 27047

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFEGSEQSFREGWRHPWLLHLWQQPLIAVIRLSASPAQALEGSTLAIRAGIRHIEITPQ
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEECCCEEEEECCC
VPRYLELIAQLRQDYPHCWVGVGTVLNRQMAEQAWQAGAQFYVCPFADESIIRWGREAGL
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCC
PIVPGALTPGEIWRAWQAGATAVKVFPAESLGGSRYLRHLQPVLGSLPLIPTGGVTLANA
CCCCCCCCHHHHHHHHHCCCCEEEEECCHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
AEYLQAGAWAVGIAGDLFPAELLSQQGVDPDSCRQELENRLRQTLQQLASQRVAAAWPEL
HHHHHHCCEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PGEPPE
CCCCCC
>Mature Secondary Structure
MVFEGSEQSFREGWRHPWLLHLWQQPLIAVIRLSASPAQALEGSTLAIRAGIRHIEITPQ
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEECCCEEEEECCC
VPRYLELIAQLRQDYPHCWVGVGTVLNRQMAEQAWQAGAQFYVCPFADESIIRWGREAGL
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCC
PIVPGALTPGEIWRAWQAGATAVKVFPAESLGGSRYLRHLQPVLGSLPLIPTGGVTLANA
CCCCCCCCHHHHHHHHHCCCCEEEEECCHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
AEYLQAGAWAVGIAGDLFPAELLSQQGVDPDSCRQELENRLRQTLQQLASQRVAAAWPEL
HHHHHHCCEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PGEPPE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6988426; 7161801; 974067 [H]