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The map label for this gene is fbp [H]

Identifier: 86606252

GI number: 86606252

Start: 1598579

End: 1599034

Strand: Reverse

Name: fbp [H]

Synonym: CYA_1589

Alternate gene names: 86606252

Gene position: 1599034-1598579 (Counterclockwise)

Preceding gene: 86606253

Following gene: 86606251

Centisome position: 54.52

GC content: 60.09

Gene sequence:

>456_bases
ATGCTGCTGCTGTTGCTGGGTTTGCTGTGGATTGGGGTGTGGGCTGGACAGCCGGCCATGGCTCTGTCGCGAGCCAAAGA
TCACCCAGCAGTTACTGTGCAATCTCAAGCCCAGCAATTTATCACCACCGAGTCGGGTCTGCAGTACTACGACCTTGTCG
AAGGTACAGGGCCTTCACCTCAGCCGGGGCAAACGGTGGTGGTGAACTACGTGGGCAAGCTGCAGGATGGCACCGTCTTC
GATAGCTCCTACAAGCGCAATCAACCTTTTACCTTCACCTACGGGGTAGGGCAGGTGATCCGTGGCTGGGAGGAAGGTCT
GGCCACCATGCGGGTGGGTGGCAAGCGGTATTTGCGCATTCCGCCGGAGTTGGCCTATGGCAGCCGCGGGGCAGGCGGGG
TGATCCCTCCCAACGCCACCCTGGACTTTGAAGTGGAGCTCCTGGCCATCCAGTAG

Upstream 100 bases:

>100_bases
GGGCAGATCGTCGAATTTGCCGAAATAGGATGAGGGGATCCCCTAAGATTGTTGGGGAGGCAAAAAGTCGGCACCGGGGG
GACGCCAACGGATGAAACAG

Downstream 100 bases:

>100_bases
ATTCAGATCTTGCAGAGACCGAATATCCAAGCGGCATTGGGCTTGTGCAGGAACTCCCTTCCCCGGAACTGTCTTCTTCT
TGGCGGCCCAGTTCTCTGGC

Product: peptidyl-prolyl cis-trans isomerase, FKBP-type

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MLLLLLGLLWIGVWAGQPAMALSRAKDHPAVTVQSQAQQFITTESGLQYYDLVEGTGPSPQPGQTVVVNYVGKLQDGTVF
DSSYKRNQPFTFTYGVGQVIRGWEEGLATMRVGGKRYLRIPPELAYGSRGAGGVIPPNATLDFEVELLAIQ

Sequences:

>Translated_151_residues
MLLLLLGLLWIGVWAGQPAMALSRAKDHPAVTVQSQAQQFITTESGLQYYDLVEGTGPSPQPGQTVVVNYVGKLQDGTVF
DSSYKRNQPFTFTYGVGQVIRGWEEGLATMRVGGKRYLRIPPELAYGSRGAGGVIPPNATLDFEVELLAIQ
>Mature_151_residues
MLLLLLGLLWIGVWAGQPAMALSRAKDHPAVTVQSQAQQFITTESGLQYYDLVEGTGPSPQPGQTVVVNYVGKLQDGTVF
DSSYKRNQPFTFTYGVGQVIRGWEEGLATMRVGGKRYLRIPPELAYGSRGAGGVIPPNATLDFEVELLAIQ

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI17149836, Length=107, Percent_Identity=52.3364485981308, Blast_Score=109, Evalue=7e-25,
Organism=Homo sapiens, GI4503725, Length=107, Percent_Identity=52.3364485981308, Blast_Score=109, Evalue=7e-25,
Organism=Homo sapiens, GI4758380, Length=92, Percent_Identity=54.3478260869565, Blast_Score=103, Evalue=4e-23,
Organism=Homo sapiens, GI206725530, Length=91, Percent_Identity=57.1428571428571, Blast_Score=102, Evalue=9e-23,
Organism=Homo sapiens, GI17149844, Length=91, Percent_Identity=57.1428571428571, Blast_Score=102, Evalue=9e-23,
Organism=Homo sapiens, GI17149842, Length=91, Percent_Identity=57.1428571428571, Blast_Score=102, Evalue=9e-23,
Organism=Homo sapiens, GI224809329, Length=126, Percent_Identity=44.4444444444444, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI224809327, Length=126, Percent_Identity=44.4444444444444, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI4758384, Length=126, Percent_Identity=44.4444444444444, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI224809331, Length=129, Percent_Identity=43.4108527131783, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI4503729, Length=99, Percent_Identity=50.5050505050505, Blast_Score=95, Evalue=2e-20,
Organism=Homo sapiens, GI4503727, Length=99, Percent_Identity=51.5151515151515, Blast_Score=93, Evalue=8e-20,
Organism=Homo sapiens, GI33469985, Length=90, Percent_Identity=46.6666666666667, Blast_Score=87, Evalue=5e-18,
Organism=Homo sapiens, GI8923659, Length=92, Percent_Identity=46.7391304347826, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI192448443, Length=90, Percent_Identity=47.7777777777778, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI206725547, Length=122, Percent_Identity=38.5245901639344, Blast_Score=78, Evalue=3e-15,
Organism=Homo sapiens, GI7706131, Length=122, Percent_Identity=39.344262295082, Blast_Score=77, Evalue=4e-15,
Organism=Homo sapiens, GI31317231, Length=123, Percent_Identity=39.0243902439024, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI150010552, Length=106, Percent_Identity=38.6792452830189, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI87082390, Length=109, Percent_Identity=55.9633027522936, Blast_Score=103, Evalue=5e-24,
Organism=Escherichia coli, GI1789745, Length=110, Percent_Identity=50.9090909090909, Blast_Score=94, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17540882, Length=98, Percent_Identity=50, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71993519, Length=107, Percent_Identity=48.5981308411215, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17561778, Length=95, Percent_Identity=45.2631578947368, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17561782, Length=90, Percent_Identity=47.7777777777778, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17506169, Length=109, Percent_Identity=34.8623853211009, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17506167, Length=109, Percent_Identity=34.8623853211009, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17561780, Length=108, Percent_Identity=36.1111111111111, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320727, Length=100, Percent_Identity=54, Blast_Score=106, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324194, Length=92, Percent_Identity=50, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323482, Length=108, Percent_Identity=44.4444444444444, Blast_Score=87, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323566, Length=108, Percent_Identity=41.6666666666667, Blast_Score=82, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24655568, Length=107, Percent_Identity=54.2056074766355, Blast_Score=116, Evalue=7e-27,
Organism=Drosophila melanogaster, GI281363946, Length=89, Percent_Identity=59.5505617977528, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17352457, Length=89, Percent_Identity=59.5505617977528, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24583150, Length=98, Percent_Identity=50, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647110, Length=111, Percent_Identity=47.7477477477478, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21356629, Length=100, Percent_Identity=54, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 16399; Mature: 16399

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLLLGLLWIGVWAGQPAMALSRAKDHPAVTVQSQAQQFITTESGLQYYDLVEGTGPSP
CHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCEEEEEECCCCCCC
QPGQTVVVNYVGKLQDGTVFDSSYKRNQPFTFTYGVGQVIRGWEEGLATMRVGGKRYLRI
CCCCEEEEEEECCCCCCEEECCCCCCCCCEEEECCHHHHHHHHHHCHHEEEECCEEEEEC
PPELAYGSRGAGGVIPPNATLDFEVELLAIQ
CCCCCCCCCCCCCCCCCCCEEEEEEEEEEEC
>Mature Secondary Structure
MLLLLLGLLWIGVWAGQPAMALSRAKDHPAVTVQSQAQQFITTESGLQYYDLVEGTGPSP
CHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCEEEEEECCCCCCC
QPGQTVVVNYVGKLQDGTVFDSSYKRNQPFTFTYGVGQVIRGWEEGLATMRVGGKRYLRI
CCCCEEEEEEECCCCCCEEECCCCCCCCCEEEECCHHHHHHHHHHCHHEEEECCEEEEEC
PPELAYGSRGAGGVIPPNATLDFEVELLAIQ
CCCCCCCCCCCCCCCCCCCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]